Molecular basis of dystrobrevin interaction with kinesin heavy chain: Structural determinants of their binding

Journal of Molecular Biology

Volumn 354, Issue 4, 2005, Pages 872-882

  Ceccarini, Marina ^a   Torreri, Paola ^a   Lombardi, Dario Giuseppe ^a   Macchia, Gianfranco ^a   Macioce, Pompeo ^a   Petrucci, Tamara C ^a  

^a ISTITUTO SUPERIORE DI SANITÀ   (Italy)

Author keywords

Binding assay; Dystrobrevin; Kinesin; Structural domains; Surface plasmon resonance

Indexed keywords

ADAPTOR PROTEIN; BETA DYSTROBREVIN; DYSTROBREVIN; ISOPROTEIN; KINESIN; MOLECULAR MOTOR; SCAFFOLD PROTEIN; UNCLASSIFIED DRUG;

ALPHA CHAIN; ARTICLE; BETA CHAIN; BINDING AFFINITY; BINDING SITE; COMPARATIVE STUDY; HEAVY CHAIN; IN VITRO STUDY; INTERMETHOD COMPARISON; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DETERMINATION; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTEIN TERTIARY STRUCTURE; PROTEIN VARIANT; QUANTITATIVE ANALYSIS; REGULATORY MECHANISM; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; SURFACE PLASMON RESONANCE;

EID: 28444441244     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2005.09.069     Document Type: Article

References (53)

1. D.J. Blake, A. Weir, S.E. Newey, and K.E. Davies Function and genetics of dystrophin and dystrophin-related proteins in muscle Physiol. Rev. 82 2002 291 329
2. M. Durbeej, and K.P. Campbell Muscular dystrophies involving the dystrophin-glycoprotein complex: an overview of current mouse models Curr. Opin. Genet. Dev. 12 2002 349 361
3. T.A. Rando The dystrophin-glycoprotein complex, cellular signaling, and the regulation of cell survival in the muscular dystrophies Muscle Nerve 24 2001 1575 1594
4. R.M. Grady, R.W. Grange, K.S. Lau, M.M. Maimone, M.C. Nichol, J.T. Stull, and J.R. Sanes Role for alpha-dystrobrevin in the pathogenesis of dystrophin-dependent muscular dystrophies Nature Cell Biol. 1 1999 215 220
5. H.J. Ambrose, D.J. Blake, R.A. Nawrotzki, and K.E. Davies Genomic organization of the mouse dystrobrevin gene: comparative analysis with the dystrophin gene Genomics 39 1997 359 369
6. M.F. Peters, K.F. O'Brien, H.M. Sadoulet-Puccio, L.M. Kunkel, M.E. Adams, and S.C. Froehner beta-dystrobrevin, a new member of the dystrophin family. Identification, cloning, and protein associations J. Biol. Chem. 272 1997 31561 31569
7. D.J. Blake, R. Nawrotzki, N.Y. Loh, D.C. Gorecki, and K.E. Davies beta-dystrobrevin, a member of the dystrophin-related protein family Proc. Natl Acad. Sci. USA 95 1998 241 246
8. C. Carr, G.D. Fischbach, and J.B. Cohen A novel 87,000-Mr protein associated with acetylcholine receptors in Torpedo electric organ and vertebrate skeletal muscle J. Cell Biol. 109 1989 1753 1764
9. K.R. Wagner, J.B. Cohen, and R.L. Huganir The 87 K postsynaptic membrane protein from Torpedo is a protein-tyrosine kinase substrate homologous to dystrophin Neuron 10 1993 511 522
10. S. Balasubramanian, E.T. Fung, and R.L. Huganir Characterization of the tyrosine phosphorylation and distribution of dystrobrevin isoforms FEBS Letters 432 1998 133 140
11. H.M. Sadoulet-Puccio, M. Rajala, and L.M. Kunkel Dystrobrevin and dystrophin: an interaction through coiled-coil motifs Proc. Natl Acad. Sci. USA 94 1997 12413 12418
12. M. Yoshida, H. Hama, M. Ishikawa-Sakurai, M. Imamura, Y. Mizuno, and K. Araishi Biochemical evidence for association of dystrobrevin with the sarcoglycan-sarcospan complex as a basis for understanding sarcoglycanopathy Hum. Mol. Genet. 9 2000 1033 1040
13. S.E. Newey, M.A. Benson, C.P. Ponting, K.E. Davies, and D.J. Blake Alternative splicing of dystrobrevin regulates the stoichiometry of syntrophin binding to the dystrophin protein complex Curr. Biol. 10 2000 1295 1298
14. M.E. Adams, H.A. Mueller, and S.C. Froehner In vivo requirement of the alpha-syntrophin PDZ domain for the sarcolemmal localization of nNOS and aquaporin-4 J. Cell Biol. 155 2001 113 122
15. J.W. Liu, Y. Wakayama, M. Inoue, S. Shibuya, H. Kojima, T. Jimi, and H. Oniki Immunocytochemical studies of aquaporin 4 in the skeletal muscle of mdx mouse J. Neurol. Sci. 164 1999 24 28
16. C. Lumeng, S. Phelps, G.E. Crawford, P.D. Walden, K. Barald, and J.S. Chamberlain Interactions between beta 2-syntrophin and a family of microtubule-associated serine/threonine kinases Nature Neurosci. 2 1999 611 617
17. S.H. Gee, R. Madhavan, S.R. Levinson, J.H. Caldwell, R. Sealock, and S.C. Froehner Interaction of muscle and brain sodium channels with multiple members of the syntrophin family of dystrophin-associated proteins J. Neurosci. 18 1998 128 137
18. N.C. Connors, M.E. Adams, S.C. Froehner, and P. Kofuji The potassium channel Kir4.1 associates with the dystrophin glycoprotein complex via alpha-syntrophin in glia J. Biol. Chem. 279 2004 28387 28392
19. S.E. Newey, E.V. Howman, C.P. Ponting, M.A. Benson, R. Nawrotzki, and N.Y. Loh Syncoilin, a novel member of the intermediate filament superfamily that interacts with alpha-dystrobrevin in skeletal muscle J. Biol. Chem. 276 2001 6645 6655
20. Y. Mizuno, T.G. Thompson, J.R. Guyon, H.G. Lidov, M. Brosius, and M. Imamura Desmuslin, an intermediate filament protein that interacts with alpha-dystrobrevin and desmin Proc. Natl Acad. Sci. USA 98 2001 6156 6161
21. D.E. Albrecht, and S.C. Froehner DAMAGE, a novel alpha-dystrobrevin- associated MAGE protein in dystrophin complexes J. Biol. Chem. 279 2004 7014 7023
22. D.J. Blake, and E. Martin-Rendon Intermediate filaments and the function of the dystrophin-protein complex Trends Cardiovasc. Med. 12 2002 224 228
23. M.A. Benson, S.E. Newey, E. Martin-Rendon, R. Hawkes, and D.J. Blake Dysbindin, a novel coiled-coil-containing protein that interacts with the dystrobrevins in muscle and brain J. Biol. Chem. 276 2001 24232 24241
24. W. Li, Q. Zhang, N. Oiso, E.K. Novak, R. Gautam, and E.P. O'Brien Hermansky-Pudlak syndrome type 7 (HPS-7) results from mutant dysbindin, a member of the biogenesis of lysosome-related organelles complex 1 (BLOC-1) Nature Genet. 35 2003 84 89
25. T. Numakawa, Y. Yagasaki, T. Ishimoto, T. Okada, T. Suzuki, and N. Iwata Evidence of novel neuronal functions of dysbindin, a susceptibility gene for schizophrenia Hum. Mol. Genet. 13 2002 2699 2708
26. R.E. Straub, Y. Jiang, C.J. MacLean, Y. Ma, B.T. Webb, and M.V. Myakishev Genetic variation in the 6p22.3 gene DTNBP1, the human ortholog of the mouse dysbindin gene, is associated with schizophrenia Am. J. Hum. Genet. 71 2002 337 348
27. M.J. Owen, N.M. Williams, and M.C. O'Donovan Dysbindin-1 and schizophrenia: from genetics to neuropathology J. Clin. Invest. 113 2004 1255 1257
28. K. Talbot, W.L. Eidem, C.L. Tinsley, M.A. Benson, E.W. Thompson, and R.J. Smith Dysbindin-1 is reduced in intrinsic, glutamatergic terminals of the hippocampal formation in schizophrenia J. Clin. Invest. 113 2004 1353 1363
29. P. Macioce, G. Gambara, M. Bernassola, L. Gaddini, P. Torreri, and G. Macchia Beta-dystrobrevin interacts directly with kinesin heavy chain in brain J. Cell Sci. 116 2003 4847 4856
30. A. Ferreira, J. Niclas, R.D. Vale, G. Banker, and K.S. Kosik Suppression of kinesin expression in cultured hippocampal neurons using antisense oligonucleotides J. Cell Biol. 117 1992 595 606
31. G. Morfini, G. Szebenyi, H. Brown, H.C. Pant, G. Pigino, and S. DeBoer A novel CDK5-dependent pathway for regulating GSK3 activity and kinesin-driven motility in neurons EMBO J. 23 2004 2235 2245
32. C.H. Kim, and J.E. Lisman A labile component of AMPA receptor-mediated synaptic transmission is dependent on microtubule motors, actin, and N-ethylmaleimide-sensitive factor J. Neurosci. 21 2001 4188 4194
33. M. Setou, D.H. Seog, Y. Tanaka, Y. Kanai, Y. Takei, M. Kawagishi, and N. Hirokawa Glutamate-receptor-interacting protein GRIP1 directly steers kinesin to dendrites Nature 417 2002 83 87
34. K. Brickley, M.J. Smith, M. Beck, and F.A. Stephenson GRIF-1 and OIP106, members of a novel gene family of coiled-coil domain proteins: association in vivo and in vitro with kinesin J. Biol. Chem. 280 2005 14723 14732
35. Y. Kanai, N. Dohmae, and N. Hirokawa Kinesin transports RNA: isolation and characterization of an RNA-transporting granule Neuron 43 2004 513 525
36. M.L. Zaccaria, F. Di Tommaso, A. Brancaccio, P. Paggi, and T.C. Petrucci Dystroglycan distribution in adult mouse brain: a light and electron microscopy study Neuroscience 104 2001 311 324
37. S. Marchand, F. Stetzkowski-Marden, and J. Cartaud Differential targeting of components of the dystrophin complex to the postsynaptic membrane Eur. J. Neurosci. 13 2001 221 229
38. N. Hirokawa, and R. Takemura Molecular motors in neuronal development, intracellular transport and diseases Curr. Opin. Neurobiol. 14 2004 564 573
39. M. Beck, K. Brickley, H.L. Wilkinson, S. Sharma, M. Smith, and P.L. Chazot Identification, molecular cloning, and characterization of a novel GABAA receptor-associated protein, GRIF-1 J. Biol. Chem. 277 2002 30079 30090
40. H. Ueda, T. Baba, N. Terada, Y. Kato, Y. Fujii, and I. Takayama Immunolocalization of dystrobrevin in the astrocytic endfeet and endothelial cells in the rat cerebellum Neurosci. Letters 283 2000 121 124
41. M.A. Benson, S.E. Newey, E. Martin-Rendon, R. Hawkes, and D.J. Blake Dysbindin, a novel coiled-coil-containing protein that interacts with the dystrobrevins in muscle and brain J. Biol. Chem. 276 2001 24232 24241
42. M. Ceccarini, P. Macioce, B. Panetta, and T.C. Petrucci Expression of dystrophin-associated proteins during neuronal differentiation of P19 embryonal carcinoma cells Neuromuscul. Disord. 12 2002 36 48
43. N.Y. Loh, H.J. Ambrose, L.M. Guay-Woodford, S. DasGupta, R.A. Nawrotzki, D.J. Blake, and K.E. Davies Genomic organization and refined mapping of the mouse beta-dystrobrevin gene Mamm. Genome. 9 1998 857 862
44. C. Xia, A. Rahman, Z. Yang, and L.S. Goldstein Chromosomal localization reveals three kinesin heavy chain genes in mouse Genomics 52 1998 209 213
45. J. Niclas, F. Navone, N. Hom-Booher, and R.D. Vale Cloning and localization of a conventional kinesin motor expressed exclusively in neurons Neuron 12 1994 1059 1072
46. H.J. Lee, Y. Yan, G. Marriott, and R.M. Corn Quantitative functional analysis of protein complexes on surfaces J. Physiol. 563 2005 61 71
47. E. Solomaha, F.L. Szeto, M.A. Yousef, and H.C. Palfrey Kinetics of Src homology 3 domain association with the proline-rich domain of dynamins: specificity, occlusion, and the effects of phosphorylation J. Biol. Chem. 280 2005 23147 23156
48. M. Ishikawa-Sakurai, M. Yoshida, M. Imamura, K.E. Davies, and E. Ozawa ZZ domain is essentially required for the physiological binding of dystrophin and utrophin to beta-dystroglycan Hum. Mol. Genet. 13 2004 693 702
49. N.Y. Loh, D. Nebenius-Oosthuizen, D.J. Blake, A.J. Smith, and K.E. Davies Role of beta-dystrobrevin in nonmuscle dystrophin-associated protein complex-like complexes in kidney and liver Mol. Cell. Biol. 21 2001 7442 7448
50. G.E. Crawford, J.A. Faulkner, R.H. Crosbie, K.P. Campbell, S.C. Froehner, and J.S. Chamberlain Assembly of the dystrophin-associated protein complex does not require the dystrophin COOH-terminal domain J. Cell Biol. 150 2000 1399 1410
51. D.J. Blake, R. Nawrotzki, M.F. Peters, S.C. Froehner, and K.E. Davies Isoform diversity of dystrobrevin, the murine 87-kDa postsynaptic protein J. Biol. Chem. 271 1996 7802 7810
52. G. Rosa, M. Ceccarini, M. Cavaldesi, M. Zini, and T.C. Petrucci Localization of the dystrophin binding site at the carboxyl terminus of β-dystroglycan Biochem. Biophys. Res. Commun. 223 1996 272 277
53. K. Russo, E. Di Stasio, G. Macchia, G. Rosa, A. Brancaccio, and T.C. Petrucci Characterization of the beta-dystroglycan-growth factor receptor 2 (Grb2) interaction Biochem. Biophys. Res. Commun. 274 2000 93 98