Composition of pH-sensitive triad in C-lobe of human serum transferrin. Comparison to sequences of ovotransferrin and lactoferrin provides insight into functional differences in iron release

Biochemistry

Volumn 44, Issue 47, 2005, Pages 15451-15460

  Halbrooks, Peter J ^a   Giannetti, Anthony M ^b,d   Klein, Joshua S ^b   Björkman, Pamela J ^b   Larouche, Julia R ^a   Smith, Valerie C ^c   MacGillivray, Ross T A ^c   Everse, Stephen J ^a   Mason, Anne B ^a,e  

^a UNIVERSITY OF VERMONT   (United States)

^b CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^d ROCHE BIOSCIENCE   (United States)

^e B402 Given Building ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BLOOD; CELLS; IRON; PH EFFECTS;

FERRIC IRON; GLYCOPROTEINS; IRON RELEASE RATE; IRON TRANSPORT PROTEINS;

PROTEINS;

AMINO ACID DERIVATIVE; ARGININE; ASPARTIC ACID; CELL SURFACE RECEPTOR; FERRIC ION; GLYCOPROTEIN; IRON; LACTOFERRIN; LYSINE DERIVATIVE; OVOTRANSFERRIN; POTASSIUM CHLORIDE; TRANSFERRIN;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; BINDING SITE; CARBOXY TERMINAL SEQUENCE; COMPARATIVE STUDY; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; ENDOCYTOSIS; GENE MUTATION; GEOMETRY; INTERNALIZATION; IRON KINETICS; IRON TRANSPORT; MOLECULAR MODEL; PH; PRIORITY JOURNAL; PROTEIN FAMILY; RECEPTOR BINDING; TITRIMETRY; TRANSFERRIN BLOOD LEVEL; WILD TYPE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; CONALBUMIN; HUMANS; HYDROGEN-ION CONCENTRATION; IRON; LACTOFERRIN; PROTEIN STRUCTURE, TERTIARY; SEQUENCE ALIGNMENT; TRANSFERRIN;

EID: 28244493040     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0518693     Document Type: Article

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