Prenatal exposure to pesticides: Analysis of human placental acetylcholinesterase, glutathione S-transferase and catalase as biomarkers of effect

Biomarkers

Volumn 10, Issue 5, 2005, Pages 376-389

  Souza, M S ^a,b   Magnarelli, G G ^a   Rovedatti, M G ^a   Santa Cruz, S ^c   de D'Angelo, A M Pechen ^a,b  

^a UNIVERSIDAD NACIONAL DEL COMAHUE   (Argentina)

^b Facultad de Ciencias Naturales e Instituto M Lillo   (Argentina)

^c Hospital Zona Cinco Saltos   (Argentina)

Author keywords

Acetylcholinesterase; Catalase; Glutathione S transferase; Intrauterine exposure; Organophosphorus pesticides; Placenta biomarkers

Indexed keywords

ACETYLCHOLINESTERASE; BIOLOGICAL MARKER; CARBAMATE PESTICIDE; CATALASE; GLUTATHIONE TRANSFERASE; ORGANOPHOSPHATE PESTICIDE; PESTICIDE; PLACENTA ENZYME;

ADULT; ARGENTINA; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; EARLY DIAGNOSIS; ENVIRONMENTAL EXPOSURE; ENZYME ACTIVITY; ENZYME ANALYSIS; FEMALE; HEAD CIRCUMFERENCE; HEALTH PROGRAM; HEALTH SURVEY; HUMAN; HUMAN TISSUE; MEDICAL INFORMATION; NEWBORN; PERINATAL CARE; POPULATION RESEARCH; PREGNANCY; PRENATAL EXPOSURE; PUBLIC HOSPITAL; SELF REPORT;

ACETYLCHOLINESTERASE; ADULT; ARGENTINA; BIOLOGICAL MARKERS; CATALASE; COHORT STUDIES; ENVIRONMENTAL EXPOSURE; FEMALE; GLUTATHIONE TRANSFERASE; HUMANS; MATERNAL EXPOSURE; PESTICIDES; PLACENTA; PREGNANCY;

EID: 28244437774     PISSN: 1354750X     EISSN: 13665804     Source Type: Journal    
DOI: 10.1080/13547500500272614     Document Type: Article

References (60)

1. Abu-Qare AW, Abou-Donia MB. 2001. Inhibition and recovery of maternal and foetal cholinesterase enzyme activity following a single cutaneous dose of methyl parathion and diazinon alone and in combination, in pregnant rats. Journal of Applied Toxicology 21:307-316.
2. Agrawal D, Sultana P, Gupta GS. 1991. Oxidative damage and changes in the glutathione redox system in erythrocytes from rats treated with hexachlorocyclohexane. Food Chemistry and Toxicology 29:459-462.
3. Beers RF, Sizer IW. 1952. A spectrophotometric method for measuring the breakdown of hydrogen peroxide by catalase. Journal of Biological Chemistry 195:133-140.
4. Benjaminov OE, Hoffer U, Aiteman J, Urbach S, Brandes JM. 1992. Parathion transfer and acetylcholinesterase activity in vivo and in-vitro perfused term human placenta. Veterinary and Human Toxicology 1:10-12.
5. Berkowitz GS, Wetmur JG, Birman-Deych E, Obel J, Lapinski RH, Godbold JH, Holzman IR, Wolff MS. 2004. In utero pesticide exposure, maternal paraoxonase activity, and head circumference. Environmental Health Perspectives 112:388-391.
6. Chan RYY, Adatia FA, Krupa AM, Jasmin BJ. 1998. Increased expression of Acetylcholinesterase T and R transcripts during hematopoietic differentiation is accompanied by parallel elevation in the levels of their respective molecular forms. Journal of Biological Chemistry 273:9727-9733.
7. Cooper GS, Martin SA, Longnecker MP, Sandler DP, Germolec DR. 2004. Associations between plasma DDE levels and immunologic measures in African-American farmers in North Carolina. Environmental Health Perspectives 112:1080-1085.
8. Costa L. 1998. Biochemical and molecular neurotoxicity: relevance to biomarkers development, neurotoxicity testing and risk assessment. Toxicology Letters 102-103:417-421.
9. Deutsch VR, Dic M, Perry C, Grisaru D, Hemo Y, Hadari D, Grant A, Eldor A, Soreq H. 2002. The stress-associated acetylcholinesterase variant AChE-R is expressed in human CD34+ hematopoietic progenitors and its C-terminal peptide ARP promotes their proliferation. Experimental Hematology 30:1153-1161.
10. Dyer SM, Cattani M, Pisaniello DL, Williams FM, Edwards JW. 2001. Peripheral cholinesterase inhibition by occupational chlorpyrifos exposure in Australian termicide applicators. Toxicology 169:177-185.
11. Ellman G, Courtney D, Valentino A, Feathersstone R. 1960. A new and rapid colorimetric determination of acetylcholinesterase activity. Biochemistry and Pharmacology 7:88-95.
12. Eskenazi B, Bradman A, Gastorin R. 1999. Exposure of children to organophosphate pesticides: their potential adverse health effects. Environmental Health Perspectives 107:409-419.
13. Eskenazi B, Harley K, Bradman A, Weltzien E, Jewell NP, Barr D, Furlong CE, Holland NT. 2004. Association of in utero organophosphate pesticide exposure and foetal growth and length of in agricultural population. Environmental Health Perspectives 10:1116-1124.
14. Falcón M, Oliva J, Osuna E, Barba A, Luna A. 2004. HCH and DDT residues in human placentas in Murcia (Spain). Toxicology 195:203-208.
15. Fenske RA, Kissel JC, Chensheng L, Kalman DA, Simcox NJ, Allen EH, Keifer MC. 2000. Biologically based pesticide dose estimates for children in an agricultural community. Environmental Health Perspectives 108:515-520.
16. Flower K, Hoppin JA, Lynch CF, Blair A, Knott C, Shore D. L. 2004. Cancer risk and parental pesticide application in children of agricultural health study participants. Environmental Health Perspectives 112:631-635.
17. Gil F, Pla A. 2001. Biomarkers as biological indicators of xenobiotic exposure - review. Journal of Applied Toxicology 21:245-255.
18. Gladen BC, Shkiryak-Nyzhnyk ZA, Chyslovsk N, Zadorozhnaja TD, Little R. 2003. Persistent organoclorine compounds and birth weight. Annals of Epidemiology 13:151-157.
19. Grisaru D, Sternfeld M, Eldor A, Glick D, Soreq H. 1999. Structural roles of acetylcholinesterase variants in biology and pathology. European Journal of Biochemistry 264:672-686.
20. Gude NM, Roberts CT, Kalionis B, King RG. 2004. Growth and function of the normal human placenta. Thrombosis Research 14:397-407.
21. Guillette EA, Meza MM, Aquilar MG, Soto AD, Garcia IE. 1998. An anthropological approach to evaluation of preschool children exposed to pesticides in Mexico. Environmental Health Perspectives 106:347-353.
22. Habig WH, Pabst CS, Jacoby WB. 1974. Glutathione S-transferases: the first enzymatic step in mercapturic acid formation. Journal of Biological Chemistry 249:7130-7139.
23. Haggarty P, Allstaff S, Hoad G, Ashton J, Abramovich DR. 2002. Placental nutrient transfer capacity and foetal growth. Placenta 23:86-92.
24. Hura C, Leanca L, Rusu L, Hura BA. 1999. Risk assessment of pollution with pesticides in food in the Eastern Romania area (1996-1997). Toxicology Letters 107:103-107.
25. Inkson CA, Brabbs AC, Grewal TS, Skerry TM, Genever PG. 2004. Characterization of acetylcholinesterase expression and secretion during osteoblast differentiation. Bone 35:819-827.
26. Iwata H, Tanabe S, Sakai N, Tatsukawa R. 1993. Distribution of persistent organochlorines in the oceanic air and surface seawater and the role of ocean on their global transport and fate. Environmental Science and Technology 27:1080-1098.
27. Jacobson JL, Jacobson SW. 1996. Dose-response in perinatal exposure to polychlorinated biphenyls (PCBs): the Michigan and North Carolina cohort studies. Toxicology and Industrial Health 12:435-444.
28. John S, Kale M, Rathone N, Bhatnagar D. 2001. Protective effect of vitamin E in dimethoate and malathion induced oxidative stress in rat erythrocytes. Journal of Nutritional Biochemistry 12:500-504.
29. Kamel F, Hoppin JA. 2004. Association of pesticide exposure with neurologic dysfunction and disease. Environmental Health Perspectives 112:950-958.
30. Kaufer D, Friedman A, Seidman S, Soreq H. 1998. Acute stress facilities long-lasting changes in cholinergic gene expression. Nature 393:373-377.
31. Kaufer D, Friedman A, Seidman S, Soreq H. 1999. Anticholinesterases induce multigenic transcriptional feedback response suppressing cholinengic neurotransmission. Chemico-Biological Interactions 119:349-360.
32. Lagueux JP, Pereg D, Ayotte P, Dewailly E, Poirier GG. 1999. Cytochrome P450 CYP1A1 enzyme activity and DNA adduct in placenta of women environmentally exposed to organochlorines. Environmental Research 80:369-382.
33. Levario Carrillo M, Feria Velasco A, De Celis L, Ramos Martínez E, Córdova Fierro L, Solís F. 2001. Parathion, a cholinesterase-inhibiting pesticide induced changes in tertiary villi of placenta of women exposed: a scanning electron microscopy study. Gynecology and Obstetric Investigations 52:269-275.
34. Lindley AA, Benson JE, Grimes C, Cole III TM, Herman AA. 1999. The relationship in neonates between clinically measured head circumference and brain volume estimated from head CT-scans. Early Human Development 56:17-29.
35. Loewy M, Kirs V, Caravajal G, Venturino A, Pechen de D'Angelo AM. 1999. Groundwater contamination by azinphos methyl in the Northern Patagonic Region (Argentina). Science of the Total Environment 225:211-218.
36. Loewy RM, Carvajal LG, Pechen de D'Angelo AM. 2003. Effect of pesticide use in fruit production orchards on shallow ground water. Journal of Environment Science and Health B38:317-325.
37. Lowry OH, Rosenbrough NJ, Farr AL, Randall RJ. 1951. Protein measurement with the Folin phenol reagent. Journal of Biological Chemistry 193:265-275.
38. Mansour SA. 2004. Pesticide exposure - Egyptian scene. Toxicology 198:91-115.
39. Martínez Montero E, Romanos Lezcano A, Praena Crespo M, Repetto Jiménez M, Martínez Ruiz D. 1993. Compuestos organoclorados: niveles sanguíneos en madres, recién nacidos, lactantes, en leche materna y de fórmula. Estudios en la provincia de Huelva. Anales Españoles de Pediatría 39:46-52.
40. Myllynen P, Pasanen M, Pelkonen O. 2005. Human placenta: a human organ for developmental toxicology research and biomonitoring. Placenta 26:361-371.
41. Nguyen N, Savitz DA, Thorp JM. 2004. Risk factors for preterm birth in Vietnam. International Journal of Gynecology and Obstetrics 86:70-78.
42. Patinkin D, Lev-Lehman E, Zacut H, Eckstein F, Soreq H. 1994. Antisense inhibition of butyrylcholinesterase gene expression predicts adverse hematopoietic consequences to cholinesterase inhibitors. Cellular and Molecular Neurobiology 14:459-473.
43. Peña Llopis S, Ferrando MD, Peña JB. 2003. Fish tolerance to organophosphate-induced oxidative stress is dependent on the glutathione metabolism and enhanced by N-acetylcysteine. Aquatic Toxicology 65:337-360.
44. Perera FP, Rauh V, Tsai W, Kinney P, Camann D, Barr D. 2003. Effects of transplacental exposure to environmental pollutants on birth outcomes in a multiethnic population. Environmental Health Perspectives 111:201-206.
45. Perera FP, Rauh V, Whyatt RM, Tsai W, Bernet JT, Tu Y, Andrews H, Ramirez J, Qu L, Tang D. 2004. Molecular evidence of an interaction between prenatal environmental exposures and birth outcomes in multiethnic population. Environmental Health Perspectives 112:626-630.
46. Pope CN. 1999. Organophosphorus pesticides: do they all have the same mechanism of toxicity? Journal of Toxicology and Environment Health B. 2:161-181.
47. Qanungo S, Sen A, Mukherjea M. 1999. Antioxidant status and lipid peroxidation in human feto-placental unit. Clinica at Chimica Acta 287:1-12.
48. Quandt SA, Doran AM, Rao P, Hoppin JA, Snively BM, Arcury TA. 2004. Reporting pesticide assessment results to farmworker families: development, implementation, and evaluation of a risk communication strategy. Environmental Health Perspectives 112:636-642.
49. Raijmarkers MTM, Bruggerman SWM, Steegers WHM, Peters L. 2002. Distribution of components of glutathion detoxification system across the human placenta after uncomplicated vaginal deliveries. Placenta 23:490-496.
50. Rama Sastry BV. 1997. Human placental cholinergic system. Biochemistry and Pharmacology 53:1577-1586.
51. Rama Sastry BV. 1999. Techniques to study human placental transport. Advanced Drug Delivery Reviews 38:17-39.
52. Rovedatti G, Magnarelli G, Sánchez S, De Rosso E, Pechén de D'Angelo AM. 2004. Exposición laboral crónica a plaguicidas organofosforados: efecto en los niveles de hormonas esteroideas, colinesterasas y parámetros hematopoyéticos. XXIV Jornadas de ATA y III Jornadas Rioplatenses, Buenos Aires 23-25 September.
53. Souza MS, Magnarelli de Potas G, Pechen de D'Angelo AM. 2004. Organophosphorus and organochlorine pesticides affect human placental phosphoinositides metabolism and PI-4 kinase activity. Journal of Biochemistry and Molecular Toxicology 18:30-36.
54. Stoll C, Alembik Y, Dott B, Roth MP. 2003. Study of placenta of children born with congenital malformations. Annales de génétique 46:1-5.
55. Voss G, Sachsse K. 1970. Red cell and plasma cholinesterase activities in microsamples of human and animal blood determined simultaneously by a modified acetylcholine/DTNB procedure. Toxicology and Applied Pharmacology 16:764-772.
56. Waliszewski SM, Aguirre A, Infanzón R, Síliceo J. 2000. Carry-over of persistent organochlorine pesticides through placenta to fetus. Salud publica de México 42:384-390.
57. Walker B, Jr, Nidiry J. 2002. Current concepts: organophosphate toxicity. Inhalation Toxicology 14:975-990.
58. Whyatt RM, Rauh V, Barr DB, Camann DE, Andrews HF, Garfinkel R, Hoepner LA, Diaz D, Dietrich J, Reyes A, et al. 2004. Prenatal insecticide exposures and birth weight and length among an urban minority cohort. Environmental Health Perspectives 112:1125-1131.
59. Willis WO, De Peyster A, Molgaard CA, Walker C, MacKendrick T. 1993. Pregnancy outcome among women exposed to pesticides through work or residence in an agricultural area. Journal of Occupational Medicine 35:943-949.
60. Woods JR. 2001. Reactive oxygen species and preterm premature rupture of membranes. Placenta 22:s38-44.