Significance and prognostic value of lysosomal enzyme activities measured in surgically operated adenocarcinomas of the gatroesophageal junction and squamous cell carcinomas of the lower third of esophagus

World Journal of Gastroenterology

Volumn 11, Issue 37, 2005, Pages 5751-5756

  Altorjay, Aaron ^a   Paal, Balazs ^a   Sohar, Nicolette ^b   Kiss, Janos ^c   Szanto, Imre ^c   Sohar, Istvan ^b  

^a St George University Teaching Hospital   (Hungary)

^b RUTGERS UNIVERSITY   (United States)

^c NATIONAL MEDICAL CENTER   (Hungary)

Author keywords

Cardiac adenocarcinomas; Esophageal squamous cell carcinoma; Lysosomal enzymes; Prognostic value; Siewert classification

Indexed keywords

ALPHA GLUCOSIDASE; ALPHA MANNOSIDASE; BETA GALACTOSIDASE; BETA GLUCURONIDASE; BETA N ACETYLHEXOSAMINIDASE; CATHEPSIN B; CATHEPSIN H; CATHEPSIN L; DIPEPTIDYL PEPTIDASE I; LYSOSOME ENZYME; PROTEINASE; THIMET OLIGOPEPTIDASE; TRIPEPTIDYL PEPTIDASE I; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CANCER ADJUVANT THERAPY; CANCER CLASSIFICATION; CANCER STAGING; CANCER SURVIVAL; CELL DIFFERENTIATION; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION FUNCTION; CYTOSOL; DATA ANALYSIS; DEATH; ENZYME ACTIVITY; ESOPHAGEAL ADENOCARCINOMA; ESOPHAGEAL SQUAMOUS CELL CARCINOMA; ESOPHAGUS RESECTION; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; LOWER ESOPHAGUS SPHINCTER; LYMPH NODE METASTASIS; MALE; POSTOPERATIVE PERIOD; PREOPERATIVE EVALUATION; PROGNOSIS; STOMACH MUCOSA; SURVIVAL RATE; TUMOR LOCALIZATION;

EID: 27944511047     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v11.i37.5751     Document Type: Article

References (38)

1. Locke GR, Talley NJ, Carpenter HA, Harmsen WS, Zinsmeister AR, Melton LJ. Changes in the site- and histology-specific incidence of gastric cancer during a 50-year period. Gastroenterology 1995; 109: 1750-1756
2. Antonioli DA, Goldman H. Changes in the location and type of gastric adenocarcinoma. Cancer 1982; 50: 775-781
3. Siewert JR, Feith M, Werner M, Stein HJ. Adenocarcinoma of the esophagogastric junction. Results of surgical therapy based on anatomical/topographic classification in 1.002 consecutive patients. Ann Surg 2000; 232: 353-361
4. Clark GWB, Smyrk TC, Burdiles P, Hoeft SF, Peters JH, Kiyabu M. Is Barrett's metaplasia the source of adenocarcinomas of the cardia? Arch Surg 1994; 129: 609-614
5. Hirai T, Kuwahar M, Yoshida K, Osaki A, Toge T. The prognostic significance of p53, p21 (Wafl, Cipl), and cyclin D1 protein expression in esophageal cancer patients. Anticancer Res 1999; 19: 4587-4591
6. Wang LS, Chow KC, Chi KH, Liu CC, Li WY, Chiu JH. Prognosis of esophageal squamous cell carcinoma: analysis of clinicopathological and biological factors. Am J Gastroenterol 1999; 94: 1933-1940
7. Zafirellis K, Dolan K, Fountolakis A, Dexter SPL, Martin IG, Sue-Ling HM. Multivariate analysis of clinical, operative and pathologic features of esophagal cancer: who needs adjuvant therapy? Dis Esoph 2002; 15: 155-159
8. Shinohara M, Aoki T, Sato S, Takagi Y, Osaka Y, Koyanagi Y. Cell cycle-regulated factors in esophageal cancer. Dis Esoph 2002; 15: 149-154
9. Shimada H, Nabeya Y, Okazumi S, Matsubara H, Miyazawa Y, Shihratori T, Hayashi H, Aoki T, Sugaya M, Guniji Y, Kobayashi S, Ochiai T. Prognostic value of preoperative serum immunosuppressive acidic protein in patients with esophageal squamous cell carcinoma. Dis Esoph 2003; 16: 102-106
10. Mullins DE, Rohrlich ST. The role of proteinases in cellular invasiveness. Biochim Biophys Acta 1983; 695: 177-214
11. Sloane BF, Hohn KV. Cysteine proteinases and metastasis. Cancer Metastasis Rev 1984; 3: 249-263
12. Duffy MJ, Ogrady P. Plasminogen activator and cancer. Eur J Cancer Clin Oncol 1984; 20: 577-582
13. Sleat DE, Sohar I, Lackland H, Majercak J, Lobel P. Rat brain contains high levels of mannose-6-phosphorylated glycoproteins including lysosomal enzymes and palmitoyl-protein thioesterase, an enzyme implicated in infantile neuronal lipofuscinosis. J Biol Chem 1996; 271: 19191-19198
14. Sleat DE, Sohar I, Pullarkat PS, Lobel P, Pullarkat RK. Specific alterations in levels of marmose 6-phosphorylated glycoproteins in different neuronal ceroid lipofuscinoses. Biochem J 1998; 334: 547-551
15. Sohar I, Lin L, Lobel P. Enzyme-based diagnosis of late infantile neuronal ceroid lipofuscinosis: comparison of tripeptidyl peptidase I and pepstatin-insensitive protease assays. Clin Chem 2000; 46: 1005-1008
16. Blot WJ, Devesa SS, Kneller RW, Fraumeni JF Jr. Rising incidence of adenocarcinoma of the esophagus and gastric cardia. JAMA 1991; 265: 1287-1289
17. Siewert JR, Feith M, Werner M, Stein HJ. Adenocarcinoma of the esophagogastric junction. Results of surgical therapy based on anatomical/topographic classification in 1.002 consecutive patients. Ann Surg 2000; 232: 353-361
18. Okabayashi T, Gotoda T, Kondo H, Inui T, Ono H, Saito D. Early carcinoma of the gastric cardia in Japan. Is it different from that in the West? Cancer 2000; 89: 2555-2559
19. Appelman HD, Kalish RJ, Clancy PE, Orringer MB. Distinguishing features of adenocarcinoma in Barrett's esophagus and in the gastric cardia. In: Speckler S J, Goyal RK, eds. Barrett's esophagus: pathophysiology, diagnosis and management. New York: Elsevier Science Publishing Co Inc 1985
20. Parsonnet J, Freidman GD, Vandersteen DP, Chang Y, Vogelman JH, Orentreich N. Helicobacter pylori infection and the risk of gastric carcinoma. N Engl J Med 1991; 325: 1127-1131
21. Forman D, Newell DG, Fullerton F, Yarnell JWG, Stacey AR, Wald N. Association between infection with Helicobacter pylori and risk of gastric cancer. Evidence from a prospective investigation. Br Med J 1991; 302: 1302-1305
22. Boyer MJ, Tannock IF. Lysosomes, lysosomal enzymes and cancer. Adv Cancer Res 1993; 60: 269-291
23. Liotta LA, Stetler-Stevenson WG. Metalloproteinases and cancer invasion. Semin Ancer Biol 1990; 1: 99-106
24. Koblinski JE, Ahram M, Sloane BF. Unraveling the role of proteases in cancer. Clin Chim Acta 2000; 291: 113-135
25. Premzl A, Puizdar V, Zavasnik-Bergant V, Kopitar-Jerala N, Lah TT, Katunuma N. Invasion of ras-transformed breast epithelial cells depends on the proteolytic activity of cysteine and aspartic proteinases. Biol Chem 2001; 382: 853-857
26. Levicar N, Nutall RK, Lah TT. Proteases in brain tumour progression. Acta Neurochir 2003; 145: 825-838
27. Yan S, Sloane BF. Molecular regulation of human cathepsin B: Implication in pathologies. Biol Chem 2003; 384: 845-854
28. Turk V, Turk B, Guncar G, Turk D, Kos J. Lysosomal cathepsins: structure, role in antigen processing and presentation, and cancer. Adv Enzyme Reg 2002; 42: 285-303
29. Lah TT, Kos J. Cysteine proteinases in cancer progression and their clinical relevance for prognosis. Biol Chem 1998; 379: 125-130
30. Lah TT, Cercek M, Blejec A, Kos J, Gorodetsky E, Somers R, Daskal I. Cathepsin B, a prognostic indicator in lymph node-negative breast carcinoma patients: comparison with cathpesin D, cathepsin L, and other clinical indicators. Clin Cancer Res 2000; 6: 578-584
31. Ledakis P, Tester WT, Rosenberg N, Romero-Fischmann D, Daskal I, Lah TT. Cathepsin D, B, and L in malignant human lung tissue. Clin Cancer Res 1996; 2: 561-568
32. Gardett EA, Reed MW, Brown NJ. Proteolysis in colorectal cancer. Mol Pathol 1999; 52: 140-145
33. Khan A, Krishna M, Baker SP, Banner BF. Cathepsin B and tumor associated laminin expression in the progression of colorectal adenoma to carcinoma. Mol Pathol 1998; 11: 704-708
34. Gil-Martin E, Rodriguez-Berrocal FJ, Paez de la Cadena M, Fernandez-Briera A. N-acetyl-beta hexosaminidase activity and isoenzymes in human gastric adenocarcinoma. Oncology 1999; 56: 142-154
35. Chung SM, Kawai K. Protease activities in gastric cancer tissues. Clin Chim Acta 1990; 189: 205-210
36. Yamamoto H, Adachi Y, Itoh F, Iku S, Matsuno K, Kusano M, Arimura Y, Endo T, Hinoda Y, Hosokawa M, Imai K. Association of matrilysin expression with recurrence and poor prognosis in human esophageal squamous cell carcinoma. Cancer Res 1999; 59: 3313-3316
37. Hughes SJ, Glover TW, Zhu XX, Kuick R, Thoraval D, Orringer MB. A novel amplicon at 8p22-23 results in overexpression of cathepsin B in esophagealadenocarcinoma. Proc Natl Acad Sci USA 1998; 95: 12410-12415
38. Izutani R, Asano S, Imano M, Kato M, Ohyanagi H, Chihara J. Are adenocarcinomas of the cardia resistant as gastric cancers to quinone anti-cancer drugs and radiation therapy? In: Giuli R, eds. The esophagogastric junction. Paris: John Libbey Eurotext 1998: 1244-1249