-
1
-
-
0025376378
-
Monoclonal antibodies to individual tyrosine phosphorylated protein substrates of oncogene-encoded tyrosine kinases
-
Kanner SB, Reynolds AB, Vines RR and Parsons JT: Monoclonal antibodies to individual tyrosine phosphorylated protein substrates of oncogene-encoded tyrosine kinases. Proc Natl Acad Sci USA 87: 3328-3332, 1992.
-
(1992)
Proc Natl Acad Sci USA
, vol.87
, pp. 3328-3332
-
-
Kanner, S.B.1
Reynolds, A.B.2
Vines, R.R.3
Parsons, J.T.4
-
2
-
-
0026612521
-
Pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions
-
Schaller MD, Borgman CA, Cob BS, Vines RR, Reynold ABs and Parsons JT: Pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions. Proc Natl Acad Sci (USA) 59: 5192-5196, 1992.
-
(1992)
Proc Natl Acad Sci (USA)
, vol.59
, pp. 5192-5196
-
-
Schaller, M.D.1
Borgman, C.A.2
Cob, B.S.3
Vines, R.R.4
Reynold, A.B.S.5
Parsons, J.T.6
-
3
-
-
0038048222
-
FAK regulates biological processes important for the pathogenesis of cancer
-
Gabarra-Nieko V, Schaller MD and Dunty JM: FAK regulates biological processes important for the pathogenesis of cancer. Cancer Metastasis Rev 22: 359-374, 2003.
-
(2003)
Cancer Metastasis Rev
, vol.22
, pp. 359-374
-
-
Gabarra-Nieko, V.1
Schaller, M.D.2
Dunty, J.M.3
-
4
-
-
0027428367
-
Identification of sequences required for the efficient localization of the focal adhesion kinase, pp125FAK, to cellular focal adhesions
-
Hildebrand JD, Schaller MD and Parsons JT: Identification of sequences required for the efficient localization of the focal adhesion kinase, pp125FAK, to cellular focal adhesions. J Cell Biol 123: 993-1005, 1993.
-
(1993)
J Cell Biol
, vol.123
, pp. 993-1005
-
-
Hildebrand, J.D.1
Schaller, M.D.2
Parsons, J.T.3
-
5
-
-
0027439594
-
Autonomous expression of a non catalytic domain of focal adhesion-associated protein tyrosine kinase pp125FAK
-
Schaller MD, Borgman CA and Parsons JT: Autonomous expression of a non catalytic domain of focal adhesion-associated protein tyrosine kinase pp125FAK. Mol Cell Biol 13: 785-791, 1993.
-
(1993)
Mol Cell Biol
, vol.13
, pp. 785-791
-
-
Schaller, M.D.1
Borgman, C.A.2
Parsons, J.T.3
-
6
-
-
0029971297
-
A mechanism for regulation of the adhesion-associated protein tyrosine kinase pp125FAK
-
Richardson A and Parsons JT: A mechanism for regulation of the adhesion-associated protein tyrosine kinase pp125FAK. Nature 380: 538-540, 1996.
-
(1996)
Nature
, vol.380
, pp. 538-540
-
-
Richardson, A.1
Parsons, J.T.2
-
7
-
-
0031750715
-
Focal adhesion kinase expression in oral cancers
-
Kornberg LJ: Focal adhesion kinase expression in oral cancers. Head Neck 20: 634-639, 1998.
-
(1998)
Head Neck
, vol.20
, pp. 634-639
-
-
Kornberg, L.J.1
-
8
-
-
0029039421
-
Overexpression of the focal adhesion kinase (p125fak) in invasive human tumors
-
Owens LV, Xu LH, Craven RJ, Dent GA, Weiner TM, Kornberg LJ, Lui ET and Cance WG: Overexpression of the focal adhesion kinase (p125fak) in invasive human tumors. Cancer Res 55: 2752-2755, 1995.
-
(1995)
Cancer Res
, vol.55
, pp. 2752-2755
-
-
Owens, L.V.1
Xu, L.H.2
Craven, R.J.3
Dent, G.A.4
Weiner, T.M.5
Kornberg, L.J.6
Lui, E.T.7
Cance, W.G.8
-
9
-
-
0033570076
-
Over expression of focal adhesion kinase, a protein tyrosine kinase, in ovarian carcinoma
-
Judson PL, He X, Cance WG and Van LEL: Over expression of focal adhesion kinase, a protein tyrosine kinase, in ovarian carcinoma. Cancer 86: 1551-1556, 1999.
-
(1999)
Cancer
, vol.86
, pp. 1551-1556
-
-
Judson, P.L.1
He, X.2
Cance, W.G.3
Van, L.E.L.4
-
10
-
-
0029795243
-
Focal adhesion kinase (pp125FAK) expression, activation and association with paxillin and p50csk in human metastatic prostate carcinoma
-
Tremblay L, Hauck W, Aprikian AG, Begin LR, Chapelaine A and Chevalier S: Focal adhesion kinase (pp125FAK) expression, activation and association with paxillin and p50csk in human metastatic prostate carcinoma. Int J Cancer 68: 164-171, 1996.
-
(1996)
Int J Cancer
, vol.68
, pp. 164-171
-
-
Tremblay, L.1
Hauck, W.2
Aprikian, A.G.3
Begin, L.R.4
Chapelaine, A.5
Chevalier, S.6
-
11
-
-
0036570357
-
Focal adhesion kinase enhances signaling through the Shc/extracellular signal-regulated kinase pathway in anaplastic astrocytoma tumor biopsy samples
-
Hecker TP, Grammer JR, Gillespie GY and Stewert J Jr: Focal adhesion kinase enhances signaling through the Shc/extracellular signal-regulated kinase pathway in anaplastic astrocytoma tumor biopsy samples. Cancer Res 62: 2699-707, 2002.
-
(2002)
Cancer Res
, vol.62
, pp. 2699-2707
-
-
Hecker, T.P.1
Grammer, J.R.2
Gillespie, G.Y.3
Stewert Jr., J.4
-
12
-
-
0034044795
-
Imunohistochemical analyses of focal adhesion kinase expression in benign and malignant human breast and colon tissues: Correlation with preinvasive and invasive phenotypes
-
Cance WG, Harris JE, Iacocca MV, Roche E, Yang X, Chang J, Simpkins S and Xu L: Imunohistochemical analyses of focal adhesion kinase expression in benign and malignant human breast and colon tissues: correlation with preinvasive and invasive phenotypes. Clin Cancer Res 6: 2417-2423, 2000.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 2417-2423
-
-
Cance, W.G.1
Harris, J.E.2
Iacocca, M.V.3
Roche, E.4
Yang, X.5
Chang, J.6
Simpkins, S.7
Xu, L.8
-
13
-
-
0037233708
-
The effects of inducible overexpression of FAK-related non-kinase (FRNK) on a transformed epithelial cell line
-
Kornberg LJ and Fleigel J: The effects of inducible overexpression of FAK-related non-kinase (FRNK) on a transformed epithelial cell line. Anticancer Res 23: 91-97, 2003.
-
(2003)
Anticancer Res
, vol.23
, pp. 91-97
-
-
Kornberg, L.J.1
Fleigel, J.2
-
14
-
-
0035099413
-
Use of Hoechst 33342 staining to detect apoptotic changes in bovine mononuclear phagocytes infected with Mycobacterium avium subsp. Paratuberculosi
-
Allen S, Sotos J, Sylte MJ and Czuprynski CJ: Use of Hoechst 33342 staining to detect apoptotic changes in bovine mononuclear phagocytes infected with Mycobacterium avium subsp. Paratuberculosi. Clin Diagn Lab Immunol 8: 460-464, 2001.
-
(2001)
Clin Diagn Lab Immunol
, vol.8
, pp. 460-464
-
-
Allen, S.1
Sotos, J.2
Sylte, M.J.3
Czuprynski, C.J.4
-
15
-
-
0032547796
-
Extracellular matrix survival signals transduced by focal adhesion kinase suppress p53-mediated apoptosis
-
Ilic D, Almeida EAC, Schlaepfer DD, Dazin P, Aizawa S and Damsky CH: Extracellular matrix survival signals transduced by focal adhesion kinase suppress p53-mediated apoptosis. J Cell Biol 143: 547-560, 1998.
-
(1998)
J Cell Biol
, vol.143
, pp. 547-560
-
-
Ilic, D.1
Almeida, E.A.C.2
Schlaepfer, D.D.3
Dazin, P.4
Aizawa, S.5
Damsky, C.H.6
-
16
-
-
2942568482
-
Induction chemotherapy to weekly paclitaxel concurrent with curative radiotherapy in stage IV (M0) unresectable head and neck squamous cell carcinoma: A dose escalation study
-
Pergolizzi S, Adamo V, Ferraro G, Sergi C, Santacaterina A, Romeo A, Zanghi C, Rosswello R and Settineri N: Induction chemotherapy to weekly paclitaxel concurrent with curative radiotherapy in stage IV (M0) unresectable head and neck squamous cell carcinoma: a dose escalation study. J Chemother 16: 201-205, 2004.
-
(2004)
J Chemother
, vol.16
, pp. 201-205
-
-
Pergolizzi, S.1
Adamo, V.2
Ferraro, G.3
Sergi, C.4
Santacaterina, A.5
Romeo, A.6
Zanghi, C.7
Rosswello, R.8
Settineri, N.9
-
17
-
-
0037276592
-
Results of phase I-II trial of concomitant hyperfractionated radiation and oral etoposide (VP-16) in patients with unresectable squamous cell carcinoma of the head and neck
-
Khafif A, Canfield VA, Syzek EJ and Medina JE: Results of phase I-II trial of concomitant hyperfractionated radiation and oral etoposide (VP-16) in patients with unresectable squamous cell carcinoma of the head and neck. Am J Otolaryngol 24: 1-5, 2003.
-
(2003)
Am J Otolaryngol
, vol.24
, pp. 1-5
-
-
Khafif, A.1
Canfield, V.A.2
Syzek, E.J.3
Medina, J.E.4
-
18
-
-
0041369959
-
FAK overexpression is correlated with tumor invasiveness and lymph node metastasis in esophageal squamous cell carcinoma
-
Miyazaki T, Kato H, Nakajima M et al: FAK overexpression is correlated with tumor invasiveness and lymph node metastasis in esophageal squamous cell carcinoma. Br J Cancer 89: 140-145, 2003.
-
(2003)
Br J Cancer
, vol.89
, pp. 140-145
-
-
Miyazaki, T.1
Kato, H.2
Nakajima, M.3
-
19
-
-
3442887394
-
Expression of focal adhesion kinase in laryngeal carcinoma
-
Yu F, Dong Y, Jiao J, Zhang H, Li X and Liang Z: Expression of focal adhesion kinase in laryngeal carcinoma. Lin Chuang Er Bi Yan Hou Ke Za Zhi 18: 149-151, 2004.
-
(2004)
Lin Chuang Er Bi Yan Hou Ke Za Zhi
, vol.18
, pp. 149-151
-
-
Yu, F.1
Dong, Y.2
Jiao, J.3
Zhang, H.4
Li, X.5
Liang, Z.6
-
20
-
-
3442890219
-
Focal adhesion kinase is overexpressed in hepatocellular carcinoma and can be served as an independent prognostic indicator
-
Fujii T, Koshikawa K, Nomoto S et al: Focal adhesion kinase is overexpressed in hepatocellular carcinoma and can be served as an independent prognostic indicator. J Hepatol 41: 104-111, 2004.
-
(2004)
J Hepatol
, vol.41
, pp. 104-111
-
-
Fujii, T.1
Koshikawa, K.2
Nomoto, S.3
-
21
-
-
2342539841
-
Expression of focal adhesion kinase in acute myeloid leukemia is associated with enhanced blast migration, increased cellularity, and poor prognosis
-
Recher C, Ysebaert L, Beyne-Rauzy O et al: Expression of focal adhesion kinase in acute myeloid leukemia is associated with enhanced blast migration, increased cellularity, and poor prognosis. Cancer Res 64: 3191-3197, 2004.
-
(2004)
Cancer Res
, vol.64
, pp. 3191-3197
-
-
Recher, C.1
Ysebaert, L.2
Beyne-Rauzy, O.3
-
22
-
-
0141672910
-
Focal adhesion kinase expression is not a prognostic predictor in colon adenocarcinoma patients
-
Theocharis SE, Kouraklis GP, Kakisis JD et al: Focal adhesion kinase expression is not a prognostic predictor in colon adenocarcinoma patients. Eur J Surg Oncol 29: 571-574, 2004.
-
(2004)
Eur J Surg Oncol
, vol.29
, pp. 571-574
-
-
Theocharis, S.E.1
Kouraklis, G.P.2
Kakisis, J.D.3
-
23
-
-
10644280092
-
Specific deletion of focal adhesion kinase suppresses tumor formation and blocks malignant progression
-
McLean GW, Komiyama NH, Serrels B, Asano H, Reynolds L, Conti F et al: Specific deletion of focal adhesion kinase suppresses tumor formation and blocks malignant progression. Genes Develop 18: 2998-3003, 2004.
-
(2004)
Genes Develop
, vol.18
, pp. 2998-3003
-
-
McLean, G.W.1
Komiyama, N.H.2
Serrels, B.3
Asano, H.4
Reynolds, L.5
Conti, F.6
-
24
-
-
0032443850
-
The COOH-terminal domain of the focal adhesion kinase induces loss of adhesion and cell death in human tumor cells
-
Xu LH, Yang X, Craven RJ and Cance WG: The COOH-terminal domain of the focal adhesion kinase induces loss of adhesion and cell death in human tumor cells. Cell Growth Diff 9: 999-10005, 1998.
-
(1998)
Cell Growth Diff
, vol.9
, pp. 999-10005
-
-
Xu, L.H.1
Yang, X.2
Craven, R.J.3
Cance, W.G.4
-
25
-
-
0035826165
-
Alterations in the focal adhesion kinase/Src signal transduction pathway correlate with increased migratory capacity of prostate carcinoma cells
-
Slack JK, Adams RB, Rovin JD et al: Alterations in the focal adhesion kinase/Src signal transduction pathway correlate with increased migratory capacity of prostate carcinoma cells. Oncogene 20: 1152-1163, 2001.
-
(2001)
Oncogene
, vol.20
, pp. 1152-1163
-
-
Slack, J.K.1
Adams, R.B.2
Rovin, J.D.3
-
26
-
-
0035423156
-
PTEN-independent induction of caspase-mediated cell death and reduced invasion by the focal adhesion targeting domain (FAT) in human astrocytic brain tumors, which highly express focal adhesion kinase (FAK)
-
Jones G, Machado J, Tolnay M et al: PTEN-independent induction of caspase-mediated cell death and reduced invasion by the focal adhesion targeting domain (FAT) in human astrocytic brain tumors, which highly express focal adhesion kinase (FAK). Cancer Res 61: 5688-5691, 2001.
-
(2001)
Cancer Res
, vol.61
, pp. 5688-5691
-
-
Jones, G.1
Machado, J.2
Tolnay, M.3
-
27
-
-
0032031062
-
Both focal adhesion kinase and c-ras are required for the enhanced matrix metalloproteinase 9 secretion by fibronectin in ovarian cancer cells
-
Shibata K, Kikkawa F, Nawa A et al: Both focal adhesion kinase and c-ras are required for the enhanced matrix metalloproteinase 9 secretion by fibronectin in ovarian cancer cells. Cancer Res 58: 900-903, 1998.
-
(1998)
Cancer Res
, vol.58
, pp. 900-903
-
-
Shibata, K.1
Kikkawa, F.2
Nawa, A.3
-
28
-
-
0242493171
-
RNA interference targeting focal adhesion kinase enhances pancreatic adenocarcinoma gemcitabine chemosensitivity
-
Duxbury MS, Ito H, Benoit E, Zinner MJ, Ashley SW and Whang EE: RNA interference targeting focal adhesion kinase enhances pancreatic adenocarcinoma gemcitabine chemosensitivity. Biochem Biophys Res Commun 311: 786-792, 2003.
-
(2003)
Biochem Biophys Res Commun
, vol.311
, pp. 786-792
-
-
Duxbury, M.S.1
Ito, H.2
Benoit, E.3
Zinner, M.J.4
Ashley, S.W.5
Whang, E.E.6
-
29
-
-
0035965234
-
Suppression of chemically induced apoptosis but not necrosis of renal proximal tubular epithelial (LLC-PK1) cells by focal adhesion kinase (FAK)
-
Van Water B, Houtepen F, Huigsloot M et al: Suppression of chemically induced apoptosis but not necrosis of renal proximal tubular epithelial (LLC-PK1) cells by focal adhesion kinase (FAK). J Biol Chem 276: 36183-36193, 2001.
-
(2001)
J Biol Chem
, vol.276
, pp. 36183-36193
-
-
Van Water, B.1
Houtepen, F.2
Huigsloot, M.3
-
30
-
-
0038125759
-
Inhibition of focal adhesion kinase by antisense oligonucleotides enhances the sensitivity of breast cancer cells to camptothecins
-
Satoh TH, Surmacz TA, Nyormoi O and Whitacre CM: Inhibition of focal adhesion kinase by antisense oligonucleotides enhances the sensitivity of breast cancer cells to camptothecins. Biocell 27: 47-55, 2003.
-
(2003)
Biocell
, vol.27
, pp. 47-55
-
-
Satoh, T.H.1
Surmacz, T.A.2
Nyormoi, O.3
Whitacre, C.M.4
-
31
-
-
0034730632
-
The focal adhesion kinase suppresses transformation-associated, anchorage-independent apoptosis in human breast cancer cells
-
Xu L-H, Yang X, Bradham CA, Brenner DA, Baldwin AS, Craven RJ and Cance WG: The focal adhesion kinase suppresses transformation-associated, anchorage-independent apoptosis in human breast cancer cells. J Biol Chem 275: 30597-306, 2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 30597-31306
-
-
Xu, L.-H.1
Yang, X.2
Bradham, C.A.3
Brenner, D.A.4
Baldwin, A.S.5
Craven, R.J.6
Cance, W.G.7
-
32
-
-
0027991315
-
Inactivation of the p53 gene by either mutation or HPV infection is extremely frequent in human oral squamous cell carcinoma cell lines
-
Min BM, Baek JH, Shin KH, Gujuluva CN, Cherrick HM and Park NH: Inactivation of the p53 gene by either mutation or HPV infection is extremely frequent in human oral squamous cell carcinoma cell lines. Eur J Cancer B Oral Oncol 5: 338-345, 1994.
-
(1994)
Eur J Cancer B Oral Oncol
, vol.5
, pp. 338-345
-
-
Min, B.M.1
Baek, J.H.2
Shin, K.H.3
Gujuluva, C.N.4
Cherrick, H.M.5
Park, N.H.6
-
33
-
-
0037945210
-
Paclitaxel increases p21 synthesis and accumulation of its AKT-phosphorylated form in the cytoplasm of cancer cells
-
Heiliez C, Baricault L, Barboule N and Valett A: Paclitaxel increases p21 synthesis and accumulation of its AKT-phosphorylated form in the cytoplasm of cancer cells. Oncogene 22: 3260-3268, 2003.
-
(2003)
Oncogene
, vol.22
, pp. 3260-3268
-
-
Heiliez, C.1
Baricault, L.2
Barboule, N.3
Valett, A.4
|