Intrahospital transport of critically ill ventilated patients: A risk factor for ventilator-associated pneumonia - A matched cohort study

Critical Care Medicine

Volumn 33, Issue 11, 2005, Pages 2471-2478

  Bercault, Nicolas ^a   Wolf, Manuel ^a   Runge, Isabelle ^a   Fleury, Jean Christian ^a   Boulain, Thierry ^a  

^a CENTRE HOSPITALIER RÉGIONAL D ORLÉANS   (France)

Author keywords

Conditional logistic regression; Cox model; Intensive care unit; Intrahospital transport; Matched cohort study; Ventilator associated pneumonia

Indexed keywords

ADULT; ARTICLE; ARTIFICIAL VENTILATION; BRONCHOSCOPY; COHORT ANALYSIS; COMPARATIVE STUDY; CONFIDENCE INTERVAL; CONTROLLED STUDY; CRITICAL ILLNESS; DEATH; ENTERIC FEEDING; FEMALE; HOSPITAL PERSONNEL; HUMAN; INTENSIVE CARE UNIT; INTUBATION; LOGISTIC REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MALE; MORTALITY; MULTIVARIATE ANALYSIS; PATIENT TRANSPORT; PRIORITY JOURNAL; PROBABILITY; RADIODIAGNOSIS; RISK ASSESSMENT; RISK FACTOR; STATISTICAL MODEL; STATISTICAL SIGNIFICANCE; SURGICAL TECHNIQUE; TREATMENT INDICATION; VENTILATOR ASSOCIATED PNEUMONIA;

EID: 27944495186     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.CCM.0000185644.54646.65     Document Type: Article

References (43)

1. Vincent JL, Bihari DJ, Suter PM, et al: The prevalence of nosocomial infection in intensive care units in Europe. JAMA 1995; 274:639-644
2. Chastre J, Fagon JY: Ventilator-associated pneumonia. Am J Respir Crit Care Med 2002; 165:867-903
3. Bowton DL: Nosocomial pneumonia in the ICU-year 2000 and beyond. Chest 1999; 115(Suppl 3):28S-33S
4. Bercault N, Boulain T: Mortality rate attributable to ventilator-associated nosocomial pneumonia in an adult intensive care unit: A prospective case-control study. Crit Care Med 2001; 29:2303-2394
5. Singh N, Falestiny MN, Rogers P, et al: Pulmonary infiltrates in the surgical ICU. Chest 1998; 114:1129-1136
6. Cunnion KM, Weber DJ, Broadhead WE, et al: Risk factors for nosocomial pneumonia: Comparing adult critical care population. Am J Respir Crit Care Med 1996; 153:158-162
7. Torres A, Gatell JM, Aznar E, et al: Re-intubation increases the risk of nosocomial pneumonia in patients needing mechanical ventilation. Am J Respir Crit Care Med 1995; 152:137-141
8. Cook DJ, Walter SD, Cook RJ, et al: Incidence of and risk factors for ventilation associated pneumonia in critically ill patients. Ann Intern Med 1998; 129:433-440
9. Kollef MH: Ventilator-associated pneumonia. JAMA 1993; 270:1965-1970
10. Apostolopoulou E, Bakakos P, Katostaras T, et al: Incidence and risk factors for ventilator-associated pneumonia in 4 multidisciplinary intensive care unit in Athens, Greece. Respir Care 2003; 48:681-688
11. Rello J, Ausina V, Castella J, et al: Nosocomial respiratory tract infections in multiple trauma patients. Chest 1992; 102:525-529
12. Chevret S, Hemmer M, Carlet J, et al: Incidence and risk factors of pneumonia acquired in intensive care unit. Intensive Care Med 1993; 19:256-264
13. Rello J, Ollendorf DA, Oster G, et al: Epidemiology and outcomes of ventilator-associated pneumonia in a large US database. Chest 2002; 122:2115-2121
14. Girou E, Stephan F, Novara A, et al: Risk factors and outcome of nosocomial infections: Result of a matched case-control study of ICU patients. Am J Respir Crit Care Med 1998; 157:1151-1158
15. Szem JW, Hydo LJ, Fischer E, et al: High-risk intrahospital transport of critically ill patients: Safety and outcome of the necessary "road trip." Crit Care Med 1995; 23:1660-1666
16. Waydas C, Schneck G, Duswald KH: Deterioration of respiratory function after intrahospital transport of critically ill surgical patients. Intensive Care Med 1995; 21:784-789
17. Marx G, Vangerow B, Hecker H, et al: Predictors of respiratory function deterioration after transfer of critically ill patients. Intensive Care Med 1998; 24:1157-1162
18. Rello J, Sonora R, Jubert P, et al: Pneumonia in intubated patients: The role of respiratory airway care. Am J Respir Crit Care Med 1996; 154:111-115
19. Drakulovic MB, Torres A, Bauer TT, et al: Supine body position as a risk factor for nosocomial pneumonia in mechanically ventilated patients: A randomised trial. Lancet 1999; 354:1851-1858
20. Kollef MH, Von Hartz B, Prentice D, et al: Patient transport from intensive care increases the risk of developing ventilator-associated pneumonia. Chest 1997; 112:765-773
21. Dupont WD: Power calculations for matched case-control studies. Biometrics 1988; 44:1157-1168
22. Le Gall JR, Lemeshow S, Saulnier F: A new simplified acute physiology score (SAPS II) based on a European/North American multicenter study. JAMA 1993; 270:2957-2963
23. Bernard GR, Artigas A, Brigham KL, et al: The American-European Consensus Conference on ARDS: Definitions, mechanisms, relevant outcomes, and clinical trial coordination. Am J Respir Crit Care Med 1994; 149:818-824
24. Bone RC, Balk RA, Cerra FB, et al: ACCP/SCCM consensus conference: Definition for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Chest 1992; 101:1644-1655
25. Torres A, El-Ebiary M, Padro L, et al: Validation of different techniques for the diagnostic of ventilator-associated pneumonia. Comparison with immediate postmortem biopsy. Am J Respir Crit Care Med 1994; 149: 324-331
26. Carli P, Adnet P, d'Athis F, et al: Recommandations de la Société Française d'Anesthésie et de Réanimation concernant les transports médicalisés intrahospitaliers. Available at: http:// www.sfar.org. Accessed February 1994
27. De Irala-Estévez J, Martinez-Concha D, Diaz-Molina C, et al: Comparison of different methodological approaches to identify risk factors of nosocomial infection in intensive care unit. Intensive Care Med 2001; 27:1254-1262
28. Knaus WA, Draper EA, Wagner DP, et al: Prognosis in acute organ-system failure. Ann Surg 1985; 202:685-693
29. Garau J, Gomez L: Pseudomonas aeruginosa pneumonia. Curr Opin Infect Dis 2003; 16:135-143
30. Knaus WA, Zimmerman JE, Wagner DP, et al: APACHE, Acute Physiology and Chronic Health Evaluation: A physiologically based classification system. Crit Care Med 1981; 9:591-597
31. MacCabe WR, Jackson GG: Gram negative bacteremia, Clinical, laboratory, and therapeutic observation. Arch Intern Med 1962; 110:856-864
32. Hosmer DW, Lemeshow S: Applied Logistic Regression. New York, Wiley, 1989, p 82-134
33. Wunderink RG, Maychall CG, Gibert C: Methodology for clinical investigation of ventilator-associated pneumonia. Chest 1992; 102(Suppl 1):580-588
34. Kaplan E, Meier P: Nonparametric estimate from incomplete observations. J Am Stat Assoc 1958; 53:457-481
35. Cox DR: Regression models and life tables. JR Stat Soc B 1972; 34:187-220
36. Arozullah AM, Khuri SF, Henderson WG, et al: Development and validation of a multifactorial risk index for predicting postoperative pneumonia after major noncardiac surgery. Ann Intern Med 2001; 135:847-857
37. Thompson WD: Statistical analysis of case control studies. Epidemiol Rev 1994; 16:33-50
38. Concato J, Feinstein AR, Holford TR: The risk of determining risk with multivariate models. Ann Intern Med 1993; 118:201-210
39. Chevret S: Logistic or Cox model to identify risk factors of nosocomial infection: Still a controversial issue. Intensive Care Med 2001; 27:1559-1560
40. Leffondre K, Abrahamowicz M, Siemiatycki J: Evaluation of Cox's model and logistic regression for matched case-control date with time-dependent covariates: A simulation study. Stat Med 2003; 22:3781-3794
41. Zanetta G, Robert D, Ghérin C: Evaluation of ventilators used during transport of ICU patients - A bench study. Intensive Care Med 2002; 28:443-451
42. Estes RJ, Meduri GU: The pathogenesis of ventilator-associated pneumonia: I. Mechanisms of bacterial transcolonization and airway inoculation. Intensive Care Med 1995; 21:365-383
43. Prats E, Dorca J, Pujol M, et al: Effects of antibiotics on protected specimen brush sampling in ventilator-associated pneumonia. Eur Respir J 2002; 19:944-951