Facile addition of alkynes to aza-aromatic systems: A new protocol for the preparation of 2-alkynyl-1,2-dihydroquinolines

Tetrahedron Letters

Volumn 46, Issue 51, 2005, Pages 8905-8908

  Yadav, J S ^a   Reddy, B V S ^a   Sreenivas, M ^a   Sathaiah, K ^a  

^a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

Author keywords

2 Alkynyl quinolines; Alkynylation; Aza aromatic compounds

Indexed keywords

ALKYNE; AROMATIC COMPOUND; COPPER IODIDE; HETEROCYCLIC COMPOUND; IODINE DERIVATIVE; ISOQUINOLINE DERIVATIVE; PYRIDINE DERIVATIVE; QUINOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; STEREOCHEMISTRY; SYNTHESIS;

EID: 27944492440     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2005.10.101     Document Type: Article

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15. 4, and concentrated in vacuo. The product was purified by column chromatography on silica gel (Merck, 100-200 mesh, ethyl acetate-hexane, 2:8) to afford 2-alkynyl-1,2-dihydroquinoline.
16. 2Na: 290.1156. Found: 290.1146.