Increased expression and activity of heme oxygenase-2 in pregnant rat aorta is not involved in attenuated vasopressin-induced contraction

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 372, Issue 3, 2005, Pages 220-227

  Katoue, Maram G ^a   Khan, Islam ^a   Oriowo, Mabayoje A ^a  

^a KUWAIT UNIVERSITY   (Kuwait)

Author keywords

Heme Oxygenase; Pregnancy; Vascular Reactivity; Vasopressin

Indexed keywords

ARGIPRESSIN; HEME OXYGENASE; HEME OXYGENASE 1; HEME OXYGENASE 2; HEME OXYGENASE INHIBITOR; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; NORADRENALIN; PROTOPORPHYRIN TIN; VASOPRESSIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA; AORTA CONSTRICTION; ARTICLE; BLOOD VESSEL REACTIVITY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; NONHUMAN; PREGNANCY; PROTEIN EXPRESSION; RAT; VASCULAR RING; WESTERN BLOTTING;

ANIMALS; AORTA; ENZYME INHIBITORS; FEMALE; HEME OXYGENASE (DECYCLIZING); MUSCLE CONTRACTION; MUSCLE, SMOOTH, VASCULAR; NG-NITROARGININE METHYL ESTER; POTASSIUM CHLORIDE; PREGNANCY; RATS; RATS, WISTAR; VASOCONSTRICTOR AGENTS; VASOPRESSINS;

EID: 27944480919     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00210-005-0018-1     Document Type: Article

References (51)

1. Abraham NG, Lin JH, Schwartzman ML, Levere RD, Shibahara S (1988) The physiological significance of heme oxygenase. Int J Biochem 20:543-558
2. Acevedo CH, Ahmed A (1998) Hemeoxygenase-1 inhibits human myometrial contractility via carbon monoxide and is upregulated by progesterone during pregnancy. J Clin Invest 101:949-955
3. Allen R, Castro L, Arora C, Krakow D, Huang S, Platt L (1994) Endothelium-derived relaxing factor inhibition and the pressor response to norepinephrine in the pregnant rat. Obstet Gynecol 83:92-96
4. Bainbridge SA, Farley AE, McLaughlin BE, Graham CH, Marks GS, Nakatsu K, Brien JF, Smith GN (2002) Carbon monoxide decreases perfusion pressure in isolated human placenta. Placenta 23:563-569
5. Barber A, Robson SC, Lyall F (1999) Hemoxygenase and nitric oxide synthase do not maintain human uterine quiescence during pregnancy. Am J Pathol 155:831-840
6. Barber A, Robson SC, Myatt L, Bulmer JN, Lyall F (2001) Heme oxygenase expression in human placenta and placental bed: reduced expression of placenta endothelial HO-2 in preeclampsia and fetal growth restriction. FASEB J 15:1158-1168
7. Bobadilla LRA, Perez-Alvarez V, Bracho Valdes I, Lopez-Sanchez P (2005) Effect of pregnancy on the roles of nitric oxide and prostaglandins in 5-HT-induced contractions in rat isolated thoracic and abdominal aorta. Clin Exp Pharmacol Physiol 32:202-209
8. Cadorette C, Sicotte B, Brochu M, St-Louis J (2000) Effects of potassium channel modulators on myotropic responses of aortic rings of pregnant rats. Am. J. Physiol. 278:H567-H576
9. Caudill TK, Resta TC, Kanagy NL, Walker BR (1998) Role of endothelial carbon monoxide in attenuated vasoreactivity following chronic hypoxia. Am. J. Physiol 275:R1025-R1030
10. Choi AM, Alam J (1996) Heme oxygenase-1: function, regulation and implication of a novel stress-inducible protein in oxidant-induced lung injury. Am J Respir Cell Mol Biol 15:9-19
11. Christodoulides N, Durante W, Kroll MH, Schafer AI (1995) Vascular smooth muscle cell heme oxygenases generate guanylyl cyclase-stimulatory carbon monoxide. Circulation 91:2306-2309
12. Chu ZM, Beilin LJ (1993) Mechanisms of vasodilatation in pregnancy: studies of the role of prostaglandins and nitric oxide in changes of vascular reactivity in the in situ blood perfused mesentery of pregnant rats. Br J Pharmacol 109:322-329
13. Coelho EB, Ballejo G, Salgado MC (1997) Nitric oxide blunts sympathetic response of pregnant normotensive and hypertensive rat arteries. Hypertension 30:585-588
14. Durante W, Schafe AI (1998) Carbon monoxide and vascular cell function. Int J Mol Med 2:255-262
15. Furchgott RF, Jothianandan D (1991) Endothelium-dependent and -independent vasodilation involving cyclic GMP: relaxation induced by nitric oxide, carbon monoxide and light. Blood Vessels 28:52-61
16. Gaine SP, Booth G, Otterbein L, Flavahan NA, Choi AM (1999) Weiner CM. Induction of heme oxygenase-1 with hemoglobin depresses vasoreactivity in rat aorta. J Vasc Res 36:114-119
17. Goetz RM, Morano I, Calovini T, Studer R, Holtz J (1994) Increased expression of endothelial constitutive nitric oxide synthase in rat aorta during pregnancy. Biochem Biophys Res Commun 205:905-910
18. Gonzales RJ, Walker BR (2002) Role of CO in attenuated vasoconstrictor reactivity of mesenteric resistance arteries after chronic hypoxia. Am J Physiol 282:H30-H37
19. Govindaraju V, Teoh H, Hamid Q, Cernacek P, Ward ME (2005) Interaction between endothelial heme oxygenase-2 and endothelin-1 in altered aortic reactivity after hypoxia in rats. Am J Physiol 288:H962-970
20. Hermsteiner M, Zoltan DR, Kunzel W (2001) The vasoconstrictor response of uterine and mesenteric resistance arteries is differentially altered in the course of pregnancy. Eur J Obstet Gynecol Reprod Biol 100:29-35
21. Jain V, Vedernikov VP, Saade GR, Chwalisz K, Garfield RE (1998) Effect of gestational age on in-vitro responses of pregnant rat aorta. Human Reprod 13:214-219
22. Khalil RA, Crews JK, Novak J, Kassab S, Granger JP (1998) Enhanced vascular reactivity during inhibition of nitric oxide synthesis in pregnant rats. Hypertension 31:1065-1069
23. Kozma F, Johnson RA, Zhang F, Yu C, Tong X, Nasjletti A (1999) Contribution of endogenous carbon monoxide to regulation of diameter in resistance vessels. Am J Physiol 276:R1087-R1094
24. Liu H, Song D, Lee SS (2001) Role of heme oxygenase-carbon monoxide pathway in pathogenesis of cirrhotic cardiomyopathy in the rat. Am J Physiol 280:G68-G74
25. Lyall F, Barber A, Myatt L, Bulmer JN, Robson SC (2000) Hemeoxygenase expression in human placenta and placental bed implies a role in regulation of trophoblast invasion and placental function. FASEB J 14:208-219
26. Maines MD (1988) Heme oxygenase: function, multiplicity, regulatory mechanisms, and clinical applications. FASEB J 2:2557-2568
27. Massicotte G, St-Louis J, Parent A, Schiffrin EL (1987) Decreased in vitro responses to vasoconstrictors during gestation in normotensive and spontaneously hypertensive rats. Can J Physiol Pharmacol 65:2466-2471
28. Massicotte G, Coderre L, Chiasson JL, Thibault G, Schiffrin EL, St-Louis J (1990) Regulation of ANG II and AVP receptors in isolated hepatocytes of pregnant rats. Am J Physiol 258:E597-E605
29. McCoubrey WK Jr, Huang TJ, Maines MD (1997) Isolation and characterization of a cDNA from the rat brain that encodes hemoprotein heme oxygenase-3. Eur J Biochem 247:725-732
30. McLaughlin BE, Lash GE, Smith GN, Marks GS, Nakatsu K, Graha CH, Brien JF (2003) Heme oxygenase expression in selected regions of term human placenta. Exp Biol Med 228:564-567
31. McLaughlin MK, Keve TM (1986) Pregnancy-induced changes in resistance blood vessels. Am J Obstet Gynecol 155:1296-1299
32. McLean M, Bowman M, Clifton V, Smith R, Grossman AB (2000) Expression of the heme oxygenase-carbon monoxide signalling system in human placenta. J Clin Endocrinol Metab 85:2345-2349
33. Molnar M, Hertelendy F (1992) N-omega-nitro-L-arginine, an inhibitor of nitric oxide synthesis, increases blood pressure in rats and reverses the pregnancy-induced refractoriness to vasopressor agents. Am J Obstet Gynecol 166:1560-1567
34. Nathan L, Cuevas J, Chaudhuri G (1995) The role of nitric oxide in the altered vascular reactivity of pregnancy in the rat. Br J Pharmacol 114:955-960
35. Nelson SH, Steinsland OS, Wang Y, Yallampalli C, Dong YL, Sanchez JM (2000) Increased nitric oxide synthase activity and expression in the human uterine artery during pregnancy. Circ Res 87:406-411
36. Paller MS (1984) Mechanism of decreased pressor responsiveness to ANG II, NE, and vasopressin in pregnant rats. Am J Physiol 247:H100-H108
37. Parent A, Schiffrin EL, St-Louis J (1990) Role of the endothelium in adrenergic responses of mesenteric artery rings of pregnant rats. Am J Obstet Gynecol 163:229-234
38. Parent A, Schiffrin EL, St-Louis J (1991) Receptors for Arg8-vasopressin, angiotensin II, and atrial natriuretic peptide in the mesenteric vasculature of pregnant rats. Can J Physiol Pharmacol 69:137-144
39. Ralevic V, Burnstock G (1996) Mesenteric arterial function in the rat in pregnancy: role of sympathetic and sensory-motor perivascular nerves, endothelium, smooth muscle, nitric oxide and prostaglandins. Br J Pharmacol 117:1463-1470
40. Rattan S, Al Haj R, De Godoy MA (2004) Mechanism of internal anal sphincter relaxation by CORM-1, authentic CO, and NANC nerve stimulation. Am J Physiol 287:G605-G611
41. Roy B, Sicotte B, Brochu M, St-Louis J (1999) Modulation of calcium mobilization in aortic rings of pregnant rats: contribution of extracellular calcium and of voltage-operated calcium channels. Biol Reprod 60:979-988
42. Sacerdoti D, Abraham NG, Oyekan AO, Yang L, Gatta A, McGiff JC (2004) Role of the heme oxygenases in abnormalities of the mesenteric circulation in cirrhotic rats. J Pharmacol Exp Ther 308:636-643
43. Samb A, Taille C, Almolki A, Megret J, Staddon JM, Aubier M, Boczkowski J (2002) Heme oxygenase modulates oxidant-signaled airway smooth muscle contractility: role of bilirubin. Am J Physiol 283:L596-L603
44. Sammut LA, Forestt R, Clark JE, Exon DJ, Vesely MJ, Sarathchandra P, Green CJ, Motterlini R (1998) Carbon monoxide is a major contributor to the regulation of vascular tone in aortas expressing high levels of heme oxygenase-1. Br J Pharmacol 125:1437-1444
45. Sladek SM, Magness RR, Conrad KP (1997) Nitric oxide and pregnancy. Am J Physiol 272:R441-R463
46. St-Louis J, Sicotte B (1992) Prostaglandin- or endothelium-mediated vasodilation is not involved in the blunted responses of blood vessels to vasoconstrictors in pregnant rats. Am J Obstet Gynecol 166:684-692
47. St-Louis J, Pare H, Roy B, Brochu M (1995) Decreased response to vasopressin in the mesenteric resistance arteries of pregnant rats: effects of nifedipine and Bay K 8644. J Soc Gynecol Investig 2:516-522
48. Wang R (1998) Resurgence of carbon monoxide: an endogenous gaseous vasorelaxing factor. Can J Physiol Pharmacol 76:1-15
49. Wang R, Wang Z, Wu L (1997) Carbon monoxide-induced vasorelaxation and the underlying mechanisms. Br J Pharmacol 121:927-934
50. Yet SF, Pellacani A, Patterson C, Tan L, Folta SC, Foster L, Lee WS, Hsieh CM, Perrella MA (1997) Induction of heme oxygenase-1 expression in vascular smooth muscle cells. A link to endotoxic shock. J Biol Chem 272:4295-4301
51. Zakhary R, Gaine SP, Dinerman JL, Ruat M, Flavahan NA, Snyder SH (1996) Heme oxygenase 2: endothelial and neuronal localization and role in endothelium-dependent relaxation. Proc Natl Acad Sci U S A 93:795-798