Synthesis and antibacterial activity of 9-substituted minocycline derivatives

Bioorganic and Medicinal Chemistry Letters

Volumn 16, Issue 2, 2006, Pages 400-403

  Sum, Phaik Eng ^a   Ross, Adma T ^a   Petersen, Peter J ^a   Testa, Raymond T ^a  

^a WYETH RESEARCH   (United States)

Author keywords

Antibiotic; Novel tetracyclines; Resistant bacteria

Indexed keywords

ANTIINFECTIVE AGENT; MINOCYCLINE; MINOCYCLINE DERIVATIVE; SULFONAMIDE; TETRACYCLINE; TETRACYCLINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL STRAIN; CONTROLLED STUDY; DRUG SYNTHESIS; GRAM POSITIVE BACTERIUM; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; SEVERE ACUTE RESPIRATORY SYNDROME; STRUCTURE ACTIVITY RELATION; SUBSTITUTION REACTION;

ANTI-BACTERIAL AGENTS; DRUG DESIGN; GRAM-POSITIVE BACTERIA; MINOCYCLINE; MOLECULAR STRUCTURE; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

BACTERIA (MICROORGANISMS); POSIBACTERIA;

EID: 27944459153     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.09.078     Document Type: Article

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