Cariporide in cardiac resuscitation - Does it really make a difference?

Critical Care Medicine

Volumn 33, Issue 11, 2005, Pages 2707-2708

  Laudi, Sven ^a   Zung, Vu Tran ^a   Steudel, Wolfgang ^a  

^a UNIVERSITY OF COLORADO   (United States)

Author keywords

Cariporide; Epinephrine; Pigs; Protein; Resuscitation; Sodium hydrogen exchanger; Ventricular fibrillation

Indexed keywords

ADRENALIN; CARIPORIDE;

CHI SQUARE DISTRIBUTION; CIRCULATION; COMPARATIVE STUDY; EDITORIAL; ELECTRIC SHOCK; HEART ARREST; HEART VENTRICLE FIBRILLATION; HEART VENTRICLE TACHYCARDIA; NONHUMAN; OXYGENATION; PRIORITY JOURNAL; REPERFUSION INJURY; RESUSCITATION;

EID: 27944442391     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.CCM.0000186885.52950.79     Document Type: Editorial

References (8)

1. Part 6: Advanced Cardiovascular Life Support: Section 8: Postresuscitation Care. Resuscitation 2000; 46:195
2. Ayoub IM, Kolarova J, Kantola RL, et al: Cariporide minimizes adverse myocardial effects of epinephrine during resuscitation from ventricular fibrillation. Crit Care Med 2005; 33:2599-2605
3. Karmazyn M, Gan XT, Humphreys RA, et al: The myocardial Na(+)-H(+) exchange: structure, regulation, and its role in heart disease. Circ Res 1999; 85:777-786
4. Zhong JQ, Dorian P: Epinephrine and vasopressin during cardiopulmonary resuscitation. Resuscitation 2005; 66:263-269
5. Haist JV, Hirst CN, Karmazyn M: Effective protection by NHE-1 inhibition in ischemic and reperfused heart under preconditioning blockade. Am J Physiol Heart Circ Physiol 2003; 284:H798-H803
6. White RD: New concepts in transthoracic defibrillation. Emerg Med Clin North Am 2002; 20:785-807
7. Karagueuzian HS, Chen PS: Cellular mechanism of reentry induced by a strong electrical stimulus: Implications for fibrillation and defibrillation. Cardiovasc Res 2001; 50:251-262
8. Rosner BA: Fundamentals of Biostatistics. Sixth Edition. Pacific Grove, CA, Duxbury, 2005