The synthesis and directed ortho-lithiation of 4-tert-butylsulfinyl[2.2] paracyclophane

Organic and Biomolecular Chemistry

Volumn 3, Issue 21, 2005, Pages 3873-3876

  Hitchcock, Peter B ^a   Rowlands, Gareth J ^a   Seacome, Richard J ^a  

^a UNIVERSITY OF SUSSEX   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DERIVATIVES; SYNTHESIS (CHEMICAL);

DIASTEREOMERS; ORTHO-LITHIATION; PARACYCLOPHANE DERIVATIVES;

ISOMERS;

EID: 27844446508     PISSN: 14770520     EISSN: None     Source Type: Journal    
DOI: 10.1039/b509994c     Document Type: Article

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29. 2, but at present the yield is not satisfactory; trapping the anion with benzaldehyde gives a 1:1 mixture of diastereoiso-mers in 30% yield. We are currently attempting to optimise this reaction.