Improved synthesis of tert-butanesulfinamide suitable for large-scale production

Organic Letters

Volumn 5, Issue 8, 2003, Pages 1317-1320

  Weix, Daniel J ^a   Ellman, Jonathan A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETONE; ALCOHOL DERIVATIVE; SOLVENT; SULFINAMIDE; TERT BUTANESULFINAMIDE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; OXIDATION; SCALE UP; SYNTHESIS;

EID: 0141628885     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol034254b     Document Type: Article

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32. Crystallized from 5 mL of hexanes/g of sulfinamide.
33. Crystallization from 10 mL of hexanes/g of sulfinamide provides enantiopure material (minor enantiomer not detectable) in 60% overall yield.