Physicochemical characterization, in vitro dissolution behavior, and pharmacodynamic studies of Rofecoxib-cyclodextrin inclusion compounds. Preparation and properties of rofecoxib hydroxypropyl β-cyclodextrin inclusion complex: A technical note

AAPS PharmSciTech

Volumn 6, Issue 1, 2005, Pages

  Baboota, Sanjula ^a   Dhaliwal, Mona ^a   Kohli, Kanchan ^a  

^a HAMDARD UNIVERSITY   (India)

Author keywords

Anti inflammatory; HP CD; In vitro dissolution; Inclusion complexes; Rofecoxib; Ulcerogenic activity

Indexed keywords

2 HYDROXYPROPYL BETA CYCLODEXTRIN; CARBOXYMETHYLCELLULOSE; ROFECOXIB;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DRUG DETERMINATION; DRUG FORMULATION; DRUG MIXTURE; DRUG SOLUBILITY; DRUG SYNTHESIS; INFRARED SPECTROSCOPY; MALE; NONHUMAN; PHARMACODYNAMICS; PHYSICAL CHEMISTRY; RAT; SCANNING ELECTRON MICROSCOPY; SPRAY DRYING; STOMACH ULCER; TABLET; X RAY DIFFRACTION;

ANIMALS; BETA-CYCLODEXTRINS; CHEMISTRY, PHARMACEUTICAL; CHEMISTRY, PHYSICAL; LACTONES; MALE; RATS; RATS, WISTAR; SOLUBILITY; STOMACH ULCER; SULFONES; TECHNOLOGY, PHARMACEUTICAL;

EID: 27744607293     PISSN: 15309932     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/pt060114     Document Type: Article

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