Partially assembled K99 fimbriae are required for protection

Infection and Immunity

Volumn 73, Issue 11, 2005, Pages 7274-7280

  Ascón, Miguel A ^b   Ochoa Repáraz, Javier ^a   Walters, Nancy ^a   Pascual, David W ^a  

^a MONTANA STATE UNIVERSITY   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; EPITOPE; ESCHERICHIA COLI ENTEROTOXIN; GAMMA INTERFERON; IMMUNOGLOBULIN A ANTIBODY; IMMUNOGLOBULIN G1 ANTIBODY; INTERLEUKIN 10; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; SALMONELLOSIS VACCINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY TITER; ANTIGEN EXPRESSION; ARTICLE; BACTERIAL OUTER MEMBRANE; BACTERIAL VIRULENCE; CYTOKINE PRODUCTION; ELECTRON MICROSCOPY; ENZYME LINKED IMMUNOSORBENT ASSAY; ESCHERICHIA COLI; FIMBRIA; IMMUNIZATION; MOUSE; NEWBORN; NONHUMAN; PLASMID; PRIORITY JOURNAL; T LYMPHOCYTE; TH2 CELL;

ANIMALS; ANIMALS, NEWBORN; ANTIBODIES, BACTERIAL; ANTIGENS, SURFACE; BACTERIAL TOXINS; COLOSTRUM; FECES; FEMALE; FIMBRIAE PROTEINS; FIMBRIAE, BACTERIAL; GENE EXPRESSION REGULATION, BACTERIAL; IMMUNITY, MUCOSAL; MALE; MICE; MICE, INBRED BALB C; MUTATION; PROTEIN TRANSPORT; SALMONELLA INFECTIONS; SALMONELLA VACCINES; TH2 CELLS; VACCINATION;

EID: 27744601980     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.73.11.7274-7280.2005     Document Type: Article

References (56)

1. Ascón, M. A., D. M. Hone, N. Walters, and D. W. Pascual. 1998. Oral immunization with a Salmonella typhimurium vaccine vector expressing recombinant enterotoxigenic Escherichia coli K99 fimbriae elicits elevated antibody titers for protective immunity. Infect. Immun. 66:5470-5476.
2. Bayer, M., K. Bischof, R. Noiges, and G. Koraimann. 2000. Subcellular localization and processing of the lytic transglycosylase of the conjugative plasmid R1. FEBS Lett. 466:389-393.
3. Black, R. E. 1992. Epidemiology of diarrhoeal disease: implications for control by vaccines. Vaccine 11:100-106.
4. Chatfield, S. N., I. G. Charles, A. J. Makoff, M. D. Oxer, G. Dougan, D. Pickard, D. Slater, and N. F. Fairweather. 1992. Use of the nirB promoter to direct the stable expression of heterologous antigens in Salmonella oral vaccine strains: development of a single-dose oral tetanus vaccine. Biotechnology (N.Y.) 10:888-892.
5. Clements, J. D., and R. A. Finkelstein. 1978. Demonstration of shared and unique immunologic determinants in enterotoxins from Vibrio cholerae and Escherichia coli. Infect. Immun. 22:709-713.
6. Collinson, S. K., L. Emody, K. H. Muller, T. J. Trust, and W. W. Kay. 1991. Purification and characterization of thin, aggregative fimbriae from Salmonella enteritidis. J. Bacteriol. 173:4773-4781.
7. + T cells. J. Exp. Med. 182:1591-1616.
8. Curtiss, R. III, R. M. Goldschmidt, N. B. Fletchall, and S. M. Kelly. 1998. A virulent Salmonella typhimurium "cya"crp oral vaccine strains expressing a streptococcal colonization and virulence antigen. Vaccine 6:155-160.
9. Daniels, N. A., J. Neimann, A. Karpati, U. D. Parashar, K. D. Greene, J. G. Wells, A. Srivastava, R. V. Tauxe, E. D. Mintz, and R. Quick. 2000. Traveler's diarrhea at sea: three outbreaks of waterborne enterotoxigenic Escherichia coli on cruise ships. J. Infect. Dis. 181:1491-1495.
10. Duchet-Suchaux, M. 1990. Protective antigens against enterotoxigenic Escherichia coli O101:K99, F41 in the infant mouse diarrhea model. Infect. Immun. 56:1364-1370.
11. Duchet-Suchaux, M., C. Le Maitre, and A. Bertin. 1990. Differences in susceptibility of inbred and outbred infant mice to enterotoxigenic Escherichia coli of bovine, porcine and human origin. J. Med. Microbiol. 31:185-190.
12. Edelman, R., R. G. Russell, G. Losonsky, B. D. Tall, C. O. Tacket, M. M. Levine, and D. H. Lewis. 1993. Immunization of rabbits with enterotoxigenic E. coli colonization factor antigen (CFA/I) encapsulated in biodegradable microspheres of poly (lactide-co-glycolide). Vaccine 11:155-158.
13. Evans, D. G., D. Y. Graham, D. J. Evans, and A. Opekun. 1984. Administration of purified colonization factor antigens (CFA/I, CFA/II) of enterotoxigenic Escherichia coli to volunteers. Gastroenterology 87:934-940.
14. Fahnert, B., J. Veijola, G. Roel, M. K. Karkkainen, A. Railo, O. Destree, S. Vainio, and P. Neubauer. 2004. Murine Wnt-1 with an internal c-myc tag recombinantly produced in Escherichia coli can induce intracellular signaling of the canonical Wnt pathway in eukaryotic cells. J. Biol. Chem. 279:47520-47527.
15. Filip, C., G. Fletcher, J. L. Wulff, and C. F. Earhart. 1973. Solubilization of the cytoplasmic membrane of Escherichia coli by the ionic detergent sodium-lauryl sarcosinate. J. Bacteriol. 115:717-722.
16. Franchini, G., M. Robert-Guroff, J. Tartaglia, A. Aggarwal, A. Abimiku, J. Benson, P. Markham, K. Limbach, G. Hurteau, and J. Fullen. 1995. Highly attenuated HIV type 2 recombinant poxviruses, but not HIV-2 recombinant Salmonella vaccines, induced long-lasting protection in rhesus macaques. AIDS Res. Hum. Retroviruses 11:909-920.
17. Galan, J. E., K. Nakayama, and R. Curtiss III. 1990. Cloning and characterization of the asd gene of Salmonella typhimurium: use in stable maintenance of recombinant plasmids in Salmonella vaccine strains. Gene 94:29-35.
18. Gentschev, I., I. Glaser, W. Goebel, D. J. McKeever, A. Musoke, and V. T. Heussler. 1998. Delivery of the p67 sporozotite antigen of Theileria parva by using recombinant Salmonella dublin: secretion of the product enhances specific antibody response in cattle. Infect. Immun. 66:2060-2064.
19. Haddad, D., S. Liljeqvist, S. Kumar, M. Hansson, S. Stahl, H. Perlmann, P. Perlmann, and K. Berzins. 1995. Surface display compared to periplasmic expression of a malarial antigen in Salmonella typhimurium and its implication for immunogenicity. FEMS Immunol. Med. Microbiol. 12:175-186.
20. Harboe, M., A. S. Malin, H. S. Dockrell, H. G. Wiker, G. Ulvund, A. Holm, M. C. Jorgensen, and P. Andersen. 1998. B-cell epitopes and quantification of the ESAT-6 protein of Mycobacterium tuberculosis. Infect. Immun. 66: 717-723.
21. + T helper cell phenotype development in a T cell receptor-αβ-transgenic model. J. Exp. Med. 182:1579-1584.
22. Inoue, O. J., J. H. Lee, and R. E. Isaacson. 1993. Transcriptional organization of the Escherichia coli pilus adhesion K99. Mol. Microbiol. 10:607-613.
23. Jiang, Z. D., J. J. Mathewson, C. D. Ericsson, A. M. Svennerholm, C. Pulido, and H. L. DuPont. 2000. Characterization of enterotoxigenic Escherichia coli strains in patients with travelers' diarrhea acquired in Guadalajara, Mexico, 1992-1997. J. Infect. Dis. 181:779-782.
24. Kang, H. Y., and R. Curtiss III. 2003. Immune responses dependent on antigen location in recombinant attenuated Salmonella typhimurium vaccines following oral immunization. FEMS Immunol. Med. Microbiol. 37:99-104.
25. Kang, H. Y., J. Srinivasan, and R. Curtiss III. 2002. Immune responses to recombinant pneumococcal PspA antigen delivered by live attenuated Salmonella enterica serovar typhimurium vaccine. Infect. Immun. 70:1739-1749.
26. Lee, J. H., and R. E. Isaacson. 1995. Expression of the gene cluster associated with the Escherichia coli pilus adhesin K99. Infect. Immun. 63:4143-4149.
27. Levine, M. M., J. A. Giron, and F. R. Noriega. 1994. Fimbrial vaccines, p. 255-270. In P. Klemm, (ed.), Fimbriae: adhesins, biogenics, genetics, and vaccines. CRC Press, Boca Raton, Fla.
28. Levine, M. M., J. G. Morris, G. Losonsky, E. C. Boedeker, and B. Rowe. 1986. Fimbriae (pili) adhesins as vaccine, p. 143-145. In D. L. Lark, S. Normark, B. E. Uhlin, and H. Wolf-Watz, (ed.), Protein-carbohydrate interactions in biological systems: molecular biology of microbial pathogenicity. Academic Press, London, England.
29. Liljeqvist, S., D. Haddad, K. Berzins, M. Uhlen, and S. Stahl. 1996. A novel expression system for Salmonella typhimurium allowing high production levels, product secretion and efficient recovery. Biochem. Biophys. Res. Commun. 218:356-359.
30. Moon, H. W. 1990. Colonization factor antigens of enterotoxigenic Escherichia coli in animals. Curr. Top. Microbiol. Immunol. 151:147-167.
31. Moon, H. W., and T. O. Bunn. 1993. Vaccines for preparing enterotoxigenic Escherichia coli infections in farm animals. Vaccine 11:213-219.
32. Murray, J. S., J. P. Kasselman, and T. Schountz. 1995. High-density presentation of an immunodominant minimal peptide on B cells is MHC-linked to Th1-like immunity. Cell. Immunol. 166:9-15.
33. Nagy, B. 1980. Vaccination of cows with a K99 extract to protect newborn calves against experimental enterotoxic colibacillosis. Infect. Immun. 27:21-24.
34. Nagy, B., and P. Z. Fekete. 1999. Enterotoxigenic Escherichia coli (ETEC) in farm animals. Vet. Res. 30:259-284.
35. Nardelli-Haeflinger, D., J.-P. Kraehenbuhl, R. Curtiss III, F. Schodel, A. Potts, S. Kelly, and P. de Grandi. 1996. Oral and rectal immunization of adult female volunteers with a recombinant attenuated Salmonella typhi vaccine strain. Infect. Immun. 64:5219-5224.
36. Nayak, A. R., S. A. Tinge, R. C. Tart, L. S. McDaniel, D. E. Briles, and R. Curtiss III. 1998. A live recombinant avirulent oral Salmonella vaccine expressing pneumococcal surface protein A induce protective responses against Streptococcus pneumoniae. Infect. Immun. 66:3744-3751.
37. + Th2 cells producing IL-6 and IL-10 are associated with mucosal immunoglobulin A responses. Infect. Immun. 64:1516-1525.
38. Pascual, D. W., D. M. Hone, S. Hall, F. W. van Ginkel, M. Yamamoto, N. Walters, K. Fujihashi, R. J. Powell, S. Wu, J. L. VanCott, H. Kiyono, and J. R. McGhee. 1999. Expression of recombinant enterotoxigenic Escherichia coli colonization factor antigen I by Salmonella typhimurium elicits a biphasic T helper cell response. Infect. Immun. 67:6249-6256.
39. Pascual, D. W., M. D. White, T. Larson, and N. Walters. 2001. Impaired mucosal immunity in L-selectin-deficient mice orally immunized with Salmonella vaccine vector. J. Immunol. 167:407-415.
40. Reid, R. H., E. C. Boedeker, C. E. McQueen, D. Davis, L. Y. Tseng, J. Kodak, K. Sau, C. L. Wilhelmsen, R. Nellore, P. Dalal, and H. R. Bhagat. 1993. Preclinical evaluation of microencapsulated CFA/II oral vaccine against enterotoxigenic E. coli. Vaccine 11:159-167.
41. Savarino, S. J., E. R. Hall, S. Bassily, F. M. Brown, F. Youssef, T. F. Wierzba, L. Peruski, N. A. El-Masry, M. Safwat, M. Rao, H. El Mohamady, R. Abu-Elyazeed, A. Naflcy, A. M. Svennerholm, M. Jertborn, Y. J. Lee, and J. D. Clemens. 1999. Oral, inactivated, whole cell enterotoxigenic Escherichia coli plus cholera toxin B subunit vaccine: results of the initial evaluation in children. PRIDE Study Group. J. Infect. Dis. 179:107-114.
42. Sehr, P., K. Zumback, and M. Pawlita. 2001. A generic capture ELISA for recombinant proteins fused to glutathione S-transferase: validation for HPV serology. J. Immunol. Methods 253:153-162.
43. Schmidt, M., E. P. Kelley, L. Y. Tseng, and E. C. Boedeker. 1985. Towards an oral E. coli pilus vaccine for travelers' diarrhea: susceptibility to proteolytic digestion. Gastroenterology 88:A1575-A1582.
44. Schountz, T., J. P. Kasselman, F. A. Martinson, L. Brown, and J. S. Murray. 1996. MHC genotype controls the capacity of ligand density to switch T helper (Th)-1/Th-2 priming in vivo. J. Immunol. 157:3893-3901.
45. Shen, H., J. F. Miller, X. Fan, D. Kolwyck, R. Ahmed, and J. T. Harty. 1998. Compartmentalization of bacterial antigens: differential effects on priming of CD8 T cells and protective immunity. Cell 92:535-545.
46. Spangler, B. D. 1992. Structure and function of cholera toxin and the related Escherichia coli heat-labile enterotoxin. Microbiol. Rev. 56:622-647.
47. Strindelius, L., L. D. Wikingsson, and I. Sjoholm. 2002. Extracellular antigens from Salmonella enteritidis induce effective immune response in mice after oral vaccination. Infect. Immun. 70:1434-1442.
48. Tacket, C. O., M. B. Sztein, S. S. Wasserman, G. Losonsky, K. L. Kotloff, T. L. Wyant, J. P. Nataro, R. Edelman, J. Perry, P. Bedford, D. Brown, S. Chatfield, G. Dougan, and M. M. Levine. 2000. Phase 2 clinical trial of attenuated Salmonella enterica serovar Typhi oral live vector vaccine CVD 908-htrA in U.S. volunteers. Infect. Immun. 68:1196-1201.
49. Titball, R. W., A. M. Howells, P.C. F. Oyston, and E. D. Williamson. 1997. Expression of Yersinia pestis capsular antigen (F1 antigen) on the surface of an aroA mutant of Salmonella typhimurium induces high levels of protection against plague. Infect. Immun. 65:1926-1930.
50. VanCott, J. L., S. N. Chatfield, M. Roberts, D. M. Hone, E. L. Hohmann, D. W. Pascual, M. Yamamoto, H. Kiyono, and J. R. McGhee. 1998. Regulation of host immune responses by modification of Salmonella virulence genes. Nat. Med. 4:1247-1252.
51. VanCott, J. L., H. F. Staats, D. W. Pascual, M. Roberts, S. N. Chatfield, M. Yamamoto, M. Coste, P. B. Carter, H. Kiyono, and J. R. McGhee. 1996. Regulation of mucosal and systemic antibody responses by T helper cell subsets, macrophages, and derived cytokines following oral immunization with live recombinant Salmonella. J. Immunol. 156:1504-1514.
52. Weinstein, D. L., B. L. O'Neill, D. M. Hone, and E. S. Metcalf. 1998. Differential early interactions between Salmonella enterica serovar typhi and two other pathogenic Salmonella serovars with intestinal epithelial cells. Infect. Immun. 66:2310-2318.
53. Wu, S., D. W. Pascual, G. K. Lewis, and D. M. Hone. 1997. Induction of mucosal and systemic responses against human immunodeficiency virus type 1 glycoprotein 120 in mice after oral immunization with a single dose of a Salmonella-HIV vector. AIDS Res. Hum. Retroviruses 13:1187-1194.
54. Wu, S., D. W. Pascual, J. L. VanCott, J. R. McGhee, D. R. Maneval, Jr., M. M. Levine, and D. M. Hone. 1995. Immune responses to novel Escherichia coli and Salmonella typhimurium vectors that express colonization factor antigen I (CFA/I) of enterotoxigenic E. coli in the absence of the CFA/I positive regulator cfaR. Infect. Immun. 63:4933-4938.
55. Yamamoto, S., H. Kiyono, M. Yamamoto, K. Imaoka, K. Fujihashi, F. W. van Ginkel, M. Noda, Y. Takeda, and J. R. McGhee. 1997. A nontoxic mutant of cholera toxin elicits Th2-type responses for enhanced mucosal immunity. Proc. Natl. Acad. Sci. USA 94:5267-5272.
56. -) vaccine expressing a major leishmanial surface protein (gp63) preferentially induces T helper 1 cells and protective immunity against leishmaniasis. J. Immunol. 145:2281-2285.