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Bioorganic and Medicinal Chemistry

Volumn 14, Issue 1, 2006, Pages 77-82

Design of multifunctional peptides expressing both antimicrobial activity and shiga toxin neutralization activity

(5) Yamada, Yoshinao a,b Miura, Yoshiko a Sakaki, Akio a Yoshida, Tetsuhiko b Kobayashi, Kazukiyo a

a NAGOYA UNIVERSITY (Japan)

b Base Technology Center (Japan)

Author keywords

Antibacterial; Drug design; Peptides; Shiga toxins

Indexed keywords

ANTIINFECTIVE AGENT; ARGINYLISOLEUCYLARGINYLLYSYLLYSYLLEUCYLARGININE; HYBRID PROTEIN; PEPTIDE DERIVATIVE; PROLYLARGINYLARGINYLARGINYLLYSINE; PROLYLLYSYLLYSYLLYSYLARGINYLLYSYLVALINE; SHIGA TOXIN; TRYPTOPHYLHISTIDYLTRYPTOPHYLLARGINYLISOLEUCYLARGINYLLYSYLLYSYLLEUCYL ARGININE; TRYPTOPHYLHISTIDYLTRYPTOPHYLTHREONYLTRYPTOPHYLLEUCINE; TRYPTOPHYLHISTIDYLTRYPTOPHYLTHREONYLTRYPTOPHYLLEUCYLARGINYLISOLEUCYL ARGINYLLYSYLLYSYLLEUCYLARGININE; TRYPTOPHYLHISTIDYLTRYPTOPHYLTHREONYLTRYPTOPHYLLEUCYLPROLYLARGINYLARGINYL ARGINYLLYSINE; TRYPTOPHYLHISTIDYLTRYPTOPHYLTHREONYLTRYPTOPHYLLEUCYLPROLYLLYSYLLYSYLLYSYL ARGINYLLYSYLVALINE; UNCLASSIFIED DRUG;

ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIOLYSIS; CELL LINE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOTOXICITY; DRUG BINDING; DRUG DESIGN; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; HUMAN; HUMAN CELL; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; SURVIVAL RATE;

AMINO ACID SEQUENCE; ANTI-BACTERIAL AGENTS; DRUG DESIGN; HELA CELLS; HUMANS; MICROBIAL SENSITIVITY TESTS; PEPTIDES; SHIGA TOXIN; SURFACE PLASMON RESONANCE;

NEGIBACTERIA; POSIBACTERIA;

EID: 27744600137 PISSN: 09680896 EISSN: None Source Type: Journal
DOI: 10.1016/j.bmc.2005.07.052 Document Type: Article

Times cited : (15)

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