Fluorine-substituted dihydrobicyclomycins: Synthesis and biochemical and biological properties

Bioorganic and Medicinal Chemistry

Volumn 14, Issue 1, 2006, Pages 41-61

  Park, Boon Saeng ^a   Widger, William ^b   Kohn, Harold ^a  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b University of Houston   (United States)

Author keywords

Bicyclomycins; Bond moment; Fluorine substitution; Inhibitory activity

Indexed keywords

5A (2 FLUOROBENZYLSULFANYL)DIHYDROBICYCLOMYCIN; 5A (2,3,4,5,6 PENTAFLUOROBENZYLSULFANYL)DIHYDROBICYCLOMYCIN; 5A (2,3,5,6 TETRAFLUOROBENZYLSULFANYL)DIHYDROBICYCLOMYCIN; 5A (2,3,6 TRIFLUOROBENZYLSULFANYL)DIHYDROBICYCLOMYCIN; 5A (2,4 DIFLUOROBENZYLSULFANYL)DIHYDROBICYCLOMYCIN; 5A (2,5 BISTRIFLUOROMETHYLBENZYLSULFANYL)DIHYDROBICYCLOMYCIN; 5A (3 CHLOROBENZYLSULFANYL)DIHYDROBICYCLOMYCIN; 5A (3 CYANOBENZYLSULFANYL)DIHYDROBICYCLOMYCIN; 5A (3 FLUOROBENZYLSULFANYL)DIHYDROBICYCLOMYCIN; 5A (3 METHOXYBENZYLSULFANYL)DIHYDROBICYCLOMYCIN; 5A (3 NITROBENZYLSULFANYL)DIHYDROBICYCLOMYCIN; 5A (3,4 DIFLUOROBENZYLSULFANYL)DIHYDROBICYCLOMYCIN; 5A (3,4,5 TRIFLUOROBENZYLSULFANYL)DIHYDROBICYCLOMYCIN; 5A (3,5 DIFLUOROBENZYLSULFANYL)DIHYDROBICYCLOMYCIN; 5A (4 FLUOROBENZYLSULFANYL)DIHYDROBICYCLOMYCIN; 5A (4 TRIFLUOROMETHYLBENZYLSULFANYL)DIHYDROBICYCLOMYCIN; 5A (BENZYLSULFANYL)DIHYDROBICYCLOMYCIN; ADENOSINE TRIPHOSPHATASE; BICOZAMYCIN DERIVATIVE; DIHYDROBICYCLOMYCIN DERIVATIVE; FLUORINE; RHO FACTOR; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL BOND; CONTROLLED STUDY; DRUG ACTIVITY; DRUG SYNTHESIS; ENZYME ACTIVITY; ESCHERICHIA COLI; IN VITRO STUDY; NONHUMAN; SUBSTITUTION REACTION;

BICYCLO COMPOUNDS, HETEROCYCLIC; FLUORINE; MAGNETIC RESONANCE SPECTROSCOPY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTROSCOPY, FOURIER TRANSFORM INFRARED;

ESCHERICHIA COLI;

EID: 27744586928     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2005.07.075     Document Type: Article

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