Ionic Basis of Tonic Firing in Spinal Substantia Gelatinosa Neurons of Rat

Journal of Neurophysiology

Volumn 91, Issue 2, 2004, Pages 646-655

  Melnick, Igor V ^a   Santos, Sónia F A ^a   Szokol, Karolina ^b   Szûcs, Péter ^b   Safronov, Boris V ^a  

^a UNIVERSITY OF PORTO   (Portugal)

^b UNIVERSITY OF DEBRECEN   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

APAMIN; BIOCYTIN; CALCIUM ACTIVATED POTASSIUM CHANNEL; VOLTAGE GATED POTASSIUM CHANNEL; VOLTAGE GATED SODIUM CHANNEL;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALCIUM CURRENT; CONTROLLED STUDY; ION CONDUCTANCE; MEMBRANE DEPOLARIZATION; MEMBRANE STEADY POTENTIAL; NERVE CELL; NERVE EXCITABILITY; NONHUMAN; PATCH CLAMP; POTASSIUM CURRENT; PRIORITY JOURNAL; RAT; SPINAL CORD; SUBSTANTIA GELATINOSA; TONICALLY FIRING NEURON;

ACTION POTENTIALS; ANIMALS; NEURONS; OSMOLAR CONCENTRATION; POTASSIUM CHANNELS; RATS; SODIUM CHANNELS; SUBSTANTIA GELATINOSA;

EID: 0842327882     PISSN: 00223077     EISSN: None     Source Type: Journal    
DOI: 10.1152/jn.00883.2003     Document Type: Article

References (46)

1. Alessandri-Haber N, Paillart C, Arsac C, Gola M, Couraud F, and Crest M. Specific distribution of sodium channels in axons of rat embryo spinal motoneurones. J Physiol 518: 203-214, 1999.
2. Barrett EF and Barrett JN. Separation of two voltage-sensitive potassium currents, and demonstration of a tetrodotoxin-resistant calcium current in frog motoneurones. J Physiol 255: 737-774, 1976.
3. Barrett JN and Crill WE. Specific membrane properties of cat motoneurones. J Physiol 239: 301-324, 1974.
4. Bentley GN and Gent JP. Electrophysiological properties of substantia gelatinosa neurones in a novel adult spinal slice preparation. J Neurosci Methods 53: 157-162, 1994.
5. Brown AG. Organization in the Spinal Cord. Berlin: Springer-Verlag, 1981.
6. Cervero F. Dorsal horn neurones and their sensory inputs. In: Spinal Afferent Processing, edited by TL Yaksh. New York: Plenum, 1987, p. 197-216.
7. Chery N, Yu XH, and De Konink Y. Visualization of lamina I of the dorsal horn in live adult rat spinal cord slices. J Neurosci Methods 96: 133-142, 2000.
8. Dodge FA and Cooley JW. Action potential of motoneuron. IBM J Res Dev 17: 219-229, 1973.
9. Dubois J-M. Evidence for the existence of three types of potassium channels in the frog Ranvier node membrane. J Physiol 318: 297-316, 1981.
10. Eckert R. Nerve cells and signals. In: Animal Physiology, edited by R Eckert and D Randall. San Francisco, CA: Freeman, 1978, p. 148-192.
11. Eckert WA, McNaughton KK, and Light AR. Morphology and axonal arborization of rat spinal inner lamina II neurons hyperpolarized by μ-opioid-selective agonists. J Comp Neurol 458: 240-256, 2003.
12. Edwards FA, Konnerth A, Sakmann B, and Takahashi T. A thin slice preparation for patch clamp recordings from neurones of the mammalian central nervous system. Pflügers Arch 414: 600-612, 1989.
13. Gobel S. Golgi studies of the neurons in layer II of the dorsal horn of the medulla (trigeminal nucleus caudalis). J Comp Neurol 180: 395-414, 1978.
14. Gobel S, Falls WM, Bennet GJ, Abdelmoumene M, Hayashi H, and Humphrey E. An EM analysis of the synaptic connections of horseradish peroxidase-filled stalked cells and islet cells in the Substantia Gelatinosa of adult cat spinal cord. J Comp Neurol 194: 781-807, 1980.
15. Grudt TJ and Perl ER. Correlations between neuronal morphology and electrophysiological features in the rodent superficial dorsal horn. J Physiol 540: 189-207, 2002.
16. Hines ML. Neuron: a program for simulation of nerve equation. In: Neural Systems: Analysis and Modeling, edited by FH Eeckman. Boston, MA: Kluwer, 1993, p. 127-136.
17. Hines ML and Carnevale NT. The NEURON simulation environment. Neural Comput 9: 1179-1209, 1997.
18. LaMotte C. Distribution of the tract of lissauer and the dorsal root fibers in the primate spinal cord. J Comp Neurol 172: 529-561, 1977.
19. Light AR and Perl ER. Differential termination of large-diameter and small-diameter primary afferent fibers in the spinal dorsal gray matter as indicated by labelling with horse-radish peroxidase. Neurosci Lett 6: 59-63, 1977.
20. Lopez-Garcia JA and King AE. Membrane properties of physiologically classified rat dorsal horn neurons in vitro: correlation with cutaneous sensory afferent input. Eur J Neurosci 6: 998-1007, 1994.
21. + channel gating between fast-spiking interneurones and principal neurones of rat hippocampus. J Physiol 505: 593-603, 1997.
22. Nishimura Y, Schwindt PC, and Crill WE. Electrical properties of facial motoneurons in brainstem slices from guinea pig. Brain Res 502: 127-142, 1989.
23. Olschewski A, Hempelmann G, Vogel W, and Safronov BV. Suppression of potassium conductance by droperidol has influence on excitability of spinal sensory neurons. Anesthesiology 94: 280-289, 2001.
24. Prescott SA and De Koninck Y. Four cell types with distinctive membrane properties and morphologies in lamina I of the spinal dorsal horn of the adult rat. J Physiol 539: 817-836, 2002.
25. Rall W. Branching dendritic trees and motoneuron membrane resistivity. Exp Neurol 1: 491-527, 1959.
26. Rall W. Time constants and electrotonic length of membrane cylinders and neurons. Biophys J 9: 1483-1508, 1969.
27. Rethelyi M. Preterminal and terminal axon arborizations in the substantia gelatinosa of cat's spinal cord. J Comp Neurol 172: 511-521, 1977.
28. Ruscheweyh R and Sandkuhler J. Lamina-specific membrane and discharge properties of rat spinal dorsal horn neurones in vitro. J Physiol 541: 231-244, 2002.
29. + channels in spinal dorsal horn neurones: role of the soma, axon and dendrites in spike generation. Prog Neurobiol 59: 217-241, 1999a.
30. + channels and their functions in small dorsal root ganglion neurones of rat. J Physiol 493: 393-408, 1996.
31. + channels in the somata of rat motoneurones. J Physiol 487: 91-106, 1995.
32. + channel on soma and processes of dorsal horn neurones of rat spinal cord. J Physiol 503: 371-385, 1997.
33. Safronov BV, Wolff M, and Vogel W. Axonal expression of sodium channels in rat spinal neurones during postnatal development. J Physiol 514: 729-734, 1999b.
34. Sather W, Dieudonné S, MacDonald JF, and Ascher P. Activation and desensitization of N-methyl-D-aspartate receptors in nucleated outside-out patches from mouse neurones. J Physiol 450: 643-672, 1992.
35. Savic N, Pedarzani P, and Sciancalepore M. Medium afterhyperpolarization and firing pattern modulation in interneurons of stratum radiatum in the CA3 hippocampal region. J Neurophysiol 85: 1986-1997, 2001.
36. Schwindt PC, Spain WJ, Foehring RC, Stafstrom CE, Chubb MC, and Crill WE. Multiple potassium conductances and their functions in neurons from cat sensorimotor cortex in vitro. J Neurophysiol 59: 424-449, 1988.
37. Smith MR, Nelson AB, and Lac S. Regulation of firing response gain by calcium-dependent mechanisms in vestibular nucleus neurons. J Neurophysiol 87: 2031-2042, 2002.
38. Stühmer W, Ruppersberg JP, Schröter KH, Sakmann B, Stocker M, Giese KP, Perschke A, Baumann A, and Pongs O. Molecular basis of functional diversity of voltage-gated potassium channels in mammalian brain. EMBO J 8: 3235-3244, 1989.
39. Sugiura Y, Lee CL, and Perl ER. Central projections of identified, unmyelinated (C) afferent fibers innervating mammalian skin. Science 234: 358-361, 1986.
40. Thomson AM, West DC, and Headley PM. Membrane characteristics and synaptic responsiveness of superficial dorsal horn neurons in a slice preparation of adult rat spinal cord. Eur J Neurosci 1: 479-488, 1989.
41. Thurbon D, Luscher HR, Hofstetter T, and Redman SJ. Passive electrical properties of ventral horn neurons in rat spinal cord slices. J Neurophysiol 80: 2485-2502, 1998.
42. Todd AJ. Electron microscope study of Golgi-stained cell in lamina II of the rat spinal dorsal horn. J Comp Neurol 275: 145-157, 1988.
43. Viana F, Bayliss DA, and Berger AJ. Multiple potassium conductances and their role in action potential repolarization and repetitive firing behavior of neonatal rat hypoglossal motoneurons. J Neurophysiol 69: 2150-2163, 1993.
44. Willis WD and Coggeshall RE. Sensory Mechanisms of the Spinal Cord. New York: Plenum, 1991.
45. + channels in soma, axon and dendrites of rat spinal neurones: ffunctional role of the soma in generation of action potentials. J Physiol 509: 767-776, 1998.
46. Yoshimura M and Jessell TM. Membrane properties of rat substantia gelatinosa neurons in vitro. J Neurophysiol 62: 109-118, 1989.