Inhibitory effects of digoxin and ouabain on aldosterone synthesis in human adrenocortical NCI-H295 cells

Journal of Cellular Physiology

Volumn 205, Issue 3, 2005, Pages 393-401

  Kau, Mei Mei ^a   Kan, Shu Fen ^b   Wang, Jiing Rong ^a   Wang, Paulus S ^b  

^a NATIONAL TAIPEI UNIVERSITY OF NURSING AND HEALTH SCIENCES   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

22 HYDROXYCHOLESTEROL; ALDOSTERONE; ALDOSTERONE SYNTHASE; ANGIOTENSIN; CALCIUM ION; CHOLESTEROL MONOOXYGENASE (SIDE CHAIN CLEAVING); CORTICOSTERONE; CORTODOXONE; CYTOCHROME P450; DIGOXIN; HYDROCORTISONE; LACTATE DEHYDROGENASE; MESSENGER RNA; OUABAIN; PREGNENOLONE; STEROID 11BETA MONOOXYGENASE; STEROIDOGENIC ACUTE REGULATORY PROTEIN;

ADRENAL CORTEX CELL; ALDOSTERONE RELEASE; ARTICLE; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CELL STRAIN; CELL STRAIN NCI H295; CONTROLLED STUDY; CULTURE MEDIUM; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME IMMUNOASSAY; ENZYME KINETICS; ENZYME REPRESSION; ENZYME SUBSTRATE; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; HYDROCORTISONE RELEASE; IC 50; MITOCHONDRION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIOIMMUNOASSAY; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STEROID METABOLISM; STEROID RELEASE; STEROIDOGENESIS; WESTERN BLOTTING;

ADRENAL CORTEX NEOPLASMS; ALDOSTERONE; ALDOSTERONE ANTAGONISTS; ALDOSTERONE SYNTHASE; CALCIUM CHANNEL BLOCKERS; CELL LINE, TUMOR; CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME; CYTOCHROME P-450 ENZYME SYSTEM; DIGOXIN; ENZYME INHIBITORS; HUMANS; HYDROCORTISONE; OUABAIN; PHOSPHOPROTEINS; RNA, MESSENGER; STEROID HYDROXYLASES;

STROPHANTHUS GRATUS;

EID: 27744561682     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcp.20415     Document Type: Article

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