Strain-specific expression of microglial keratan sulfate proteoglycans in the normal rat central nervous system: Inverse correlation with constitutive expression of major histocompatibility complex class II antigens

GLIA

Volumn 18, Issue 3, 1996, Pages 255-260

  Jander, Sebastian ^a   Stoll, Guido ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

Experimental autoimmune encephalomyelitis; Susceptibility

Indexed keywords

KERATAN SULFATE; MONOCLONAL ANTIBODY; PROTEOGLYCAN;

ANIMAL; ARTICLE; BROWN NORWAY RAT; CYTOLOGY; FISCHER 344 RAT; LEWIS RAT; MAJOR HISTOCOMPATIBILITY COMPLEX; METABOLISM; MICROGLIA; NERVOUS SYSTEM; PHYSIOLOGY; POLYACRYLAMIDE GEL ELECTROPHORESIS; RAT; SPECIES DIFFERENCE; SPINAL CORD; WESTERN BLOTTING;

ANIMALS; ANTIBODIES, MONOCLONAL; BLOTTING, WESTERN; ELECTROPHORESIS, POLYACRYLAMIDE GEL; KERATAN SULFATE; MAJOR HISTOCOMPATIBILITY COMPLEX; MICROGLIA; NERVOUS SYSTEM; PROTEOGLYCANS; RATS; RATS, INBRED BN; RATS, INBRED F344; RATS, INBRED LEW; SPECIES SPECIFICITY; SPINAL CORD;

EID: 0030293038     PISSN: 08941491     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-1136(199611)18:3<255::AID-GLIA9>3.0.CO;2-Y     Document Type: Article

References (24)

1. Bertolotto, A., Caterson, B., Canavese, G., Migheli, A., and Schiffer, D. (1993) Monoclonal antibodies to keratan sulfate immunolocalize ramified microglia in paraffin and cryostat sections of rat brain. J. Histochem. Cytochem., 41:481-487.
2. Bö, L., Mörk, S., Kong, P.A., Nyland, H., Pardo, C.A., and Trapp, B.D. (1994) Detection of MHC class-II-antigens on macrophages and microglia, but not astrocytes and endothelia in active multiple sclerosis lesions. J. Neuroimmunol., 51:135-146.
3. Chung, I.Y., Norris, J.G., and Benveniste, E.N. (1991) Differential tumor necrosis factor α expression by astrocytes from experimental allergic encephalomyelitis-susceptible and -resistant rat strains. J. Exp. Med., 173:801-811.
4. + T cells compared. J. Immunol., 154:4309-4321.
5. Frei, K., Siepl, C., Groscurth, P., Bodmer, S., Schwerdel, C., and Fontana, A. (1987) Antigen presentation and tumor cytotoxicity by interferon-gamma-treated microglial cells. Eur. J. Immunol., 17: 1271-1278.
6. Gasser, D.L., Palm, J., and Gonatas, N.K. (1975) Genetic control of susceptibility to experimental allergic encephalomyelitis and the Ag-B locus of rats. J. Immunol., 115:431-433.
7. Happ, M.P., Wettstein, P., Dietzschold, B., and Heber-Katz, E. (1988) Genetic control of the development of experimental allergic encephalomyelitis in rats: Separation of MHC and non-MHC gene effects. J. Immunol., 141:1489-1494.
8. Hickey, W.F., Vass, K., and Lassman, H. (1992) Bone marrow-derived elements in the central nervous system: An immunohistochemical and ultrastructural survey of rat chimeras. J. Neuropathol. Exp. Neurol., 51:246-256.
9. Jander, S. and Stoll, G. (1996) Downregulation of microglial keratan sulfate proteoglycans coincident with lymphomonocytic infiltration of the rat central nervous system. Am. J. Pathol., 148:71-78.
10. Källén, B. (1982) Rats highly susceptible to experimental autoimmune encephalomyelitis obtained by crossing rats from strains with low susceptibility. J. Immunogenet., 9:335-342.
11. Ling, E.A. and Wong, W.C. (1993) The origin and nature of ramified and amoeboid microglia: A historical review and current concepts. Glia, 7:9-18.
12. Liu, W., Brosnan, C.F., Dickson, D.W., and Lee, S.C. (1994) Macrophage colony-stimulating factor mediates astrocyte-induced microglial ramification in human fetal central nervous system culture. Am. J. Pathol. 145:48-53.
13. Lortat-Jacob, H. and Grimaud, J.-A. (1991) Interferon-gamma binds to heparan sulfate by a cluster of amino acids located in the C-terminal part of the molecule. FEBS Lett., 280:152-154.
14. Lopez-Casillas, F., Wrana, J.L., and Massagué, J. (1993) Betaglycan presents ligand to the TGFβ signaling receptor. Cell, 73:1435-1444.
15. Mason, D.W., MacPhee, I.A.M., and Antoni, F. (1990) The role of the neuroendocrine system in determining genetic susceptibility to experimental allergic encephalomyelitis in the rat. Immunology, 70:1-5.
16. Perry, V.H. and Gordon, S. (1988) Macrophages and microglia in the nervous system. Trends Neurosci., 11:273-277.
17. Renno, T., Krakowski, M., Piccirillo, C., Lin, Y.-Y., and Owens. T. (1995) TNF-α expression by resident microglia and infiltrating leukocytes in the central nervous system of mice with experimental allergic encephalomyelitis: Regulation by Th1 cytokines. J. Immunol, 154:944-953.
18. Ruoslahti, E. and Yamaguchi, Y. (1991) Proteoglycans as modulators of growth factor activities. Cell, 64:867-869.
19. Sedgwick, J.D., Schwendner, S., Gregersen, R., Dorries, R., and Ter Meulen, V (1993) Resident macrophages (ramified microglia) of the adult brown Norway rat central nervous system are constitutively major histocompatibility complex class II positive. J. Exp. Med., 177:1145-1152.
20. Sievers, J., Parwaresch, R., and Wottge, H.-U. (1995) Blood monocytes and spleen macrophages differentiate into microglia-like cells on monolayers of astrocytes: Morphology. Glia, 12:245-258.
21. Stepaniak, J.A., Gould, K.E., Sun, D., and Swanborg, R.H. (1995) A comparative study of experimental autoimmune encephalomyelitis in Lewis and DA rats. J. Immunol., 155:2762-2769.
22. Stoll, G., Trapp, B.D., and Griffin, J.W. (1989) Macrophage function during wallerian degeneration of rat optic nerve: Clearance of degenerating myelin and Ia expression. J. Neurosci., 9:2327-2335.
23. Streit, W.J., Graeber, M.B., and Kreutzberg, G.W. (1988) Functional plasticity of microglia: A review. Glia, 1:301-307.
24. Tanaka, Y, Adams, D.H., Hubscher, S., Hirano, H., Siebenlist, U., and Shaw, S. (1993) T-cell adhesion induced by proteoglycan-immobilized cytokine MIP-1β. Nature, 361:79-82.