Combined analysis of polymorphisms in angiotensinogen and adducin genes and their effects on hypertension in a Japanese sample: The Shigaraki study

Hypertension Research

Volumn 28, Issue 8, 2005, Pages 645-650

  Tamaki, Shinji ^d   Nakamura, Yasuyuki ^a   Tabara, Yasuharu ^b   Okamura, Tomonori ^c   Kita, Yoshikuni ^c   Kodawaki, Takashi ^c   Tsujita, Yasuyuki ^c   Horie, Minoru ^c   Miki, Tetsuro ^b   Ueshima, Hirotsugu ^c  

^a KYOTO WOMEN'S UNIVERSITY   (Japan)

^b EHIME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c SHIGA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

^d Kohka Public Hospital   (Japan)

Author keywords

Adducin Gly460Trp polymorphism; Angiotensinogen M235T polymorphism; Hypertension; Lifestyle

Indexed keywords

ADDUCIN; ANGIOTENSINOGEN; GLYCINE; THREONINE; TRYPTOPHAN;

ADULT; AGED; ALCOHOL CONSUMPTION; ARTICLE; BLOOD PRESSURE MEASUREMENT; BODY MASS; CARDIOVASCULAR RISK; CONFIDENCE INTERVAL; CORRELATION ANALYSIS; DIASTOLIC BLOOD PRESSURE; FAMILY HISTORY; FEMALE; GENE INTERACTION; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC RISK; HOMOZYGOSITY; HUMAN; HYPERTENSION; JAPAN; LIFESTYLE; MAJOR CLINICAL STUDY; MALE; MEDICAL EXAMINATION; MULTIPLE REGRESSION; POPULATION RESEARCH; REGRESSION ANALYSIS; RISK ASSESSMENT; RISK FACTOR; SALT INTAKE; SYSTOLIC BLOOD PRESSURE;

ADULT; AGED; ANGIOTENSINOGEN; BLOOD PRESSURE; CALMODULIN-BINDING PROTEINS; FEMALE; GENOTYPE; HOMOZYGOTE; HUMANS; HYPERTENSION; JAPAN; LIFE STYLE; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; ODDS RATIO; POLYMORPHISM, GENETIC; QUESTIONNAIRES; REGRESSION ANALYSIS; SODIUM CHLORIDE, DIETARY;

EID: 27744544930     PISSN: 09169636     EISSN: 13484214     Source Type: Journal    
DOI: 10.1291/hypres.28.645     Document Type: Article

References (22)

1. Kunz R, Kreutz R, Beige J, Distler A, Sharma AM: Association between the angiotensinogen 235T-variant and essential hypertension in whites: a systematic review and methodological appraisal. Hypertension 1997; 30: 1331-1337.
2. Katsuya T, Ishikawa K, Sugimoto K, Rakugi H, Ogihara T: Salt sensitivity of Japanese from the viewpoint of gene polymorphism. Hypertens Res 2003; 26: 521-525.
3. Hunt SC, Geleijnse JM, Wu LL, Witteman JC, Williams RR, Grobbee DE: Enhanced blood pressure response to mild sodium reduction in subjects with the 235T variant of the angiotensinogen gene. Am J Hypertens 1999; 12: 460-466.
4. Schorr U, Blaschke K, Beige J, Distler A, Sharma AM: Angiotensinogen M235T variant and salt sensitivity in young normotensive Caucasians. J Hypertens 1999; 17: 475-479.
5. Beeks E, Janssen RG, Kroon AA, et al: Association between the alpha-adducin Gly460Trp polymorphism and systolic blood pressure in familial combined hyperlipidemia. Am J Hypertens 2001; 14: 1185-1190.
6. Cusi D, Barlassina C, Azzani T, et al: Polymorphisms of alpha-adducin and salt sensitivity in patients with essential hypertension. Lancet 1997; 10; 349: 1353-1357.
7. Tamaki S, Iwai N, Tsujita Y, Nakamura Y, Kinoshita M: Polymorphism of alpha-adducin in Japanese patients with essential hypertension. Hypertens Res 1998; 21: 29-32.
8. Yamagishi K, Iso H, Tanigawa T, Cui R, Kudo M, Shimamoto T: Alpha-adducin G460W polymorphism, urinary sodium excretion, and blood pressure in community-based samples. Am J Hypertens 2004; 17: 385-390.
9. Nakamura Y, Amamoto K, Tamaki S, et al: Genetic variation in aldehyde dehydrogenase 2 and the effect of alcohol consumption on cholesterol levels. Atherosclerosis 2002; 164: 171-177.
10. m mitochondrial acetaldehyde dehydrogenase genotypes with blood pressure level and the prevalence of hypertension in a general population Hypertens Res 2002; 25: 857-864.
11. Tamaki S, Nakamura Y, Tsujita Y, et al: Polymorphism of the angiotensin converting enzyme gene and blood pressure in a Japanese general population (the Shigaraki Study). Hypertens Res 2002; 25: 843-848.
12. Bennett CL, Schrader AP, Morris BJ: Cross-sectional analysis of Met235→Thr variant of angiotensinogen gene in severe, Familial Hypertension. Biochem Biophys Res Commun 1993; 197: 833-839.
13. Sugimoto K, Hozawa A, Katsuya T, et al: alpha-Adducin Gly460Trp polymorphism is associated with low renin hypertension in younger subjects in the Ohasama study. J Hypertens 2002; 20: 1779-1784.
14. Luft FC, Miller JZ, Weinberger MH, Christian JC, Skrabal F: Genetic influences on the response to dietary salt reduction, acute salt loading, or salt depletion in humans. J Cardiovasc Pharmacol 1988; 12: S49-S55.
15. Miller JZ, Weinberger MH, Christian JC, Daugherty SA: Familial resemblance in the blood pressure response to sodium restriction. Am J Epidemiol 1987; 126: 822-830.
16. Hunt SC, Cook NR, Oberman A, et al: Angiotensinogen genotype, sodium reduction, weight loss, and prevention of hypertension. Trials of hypertension prevention, Phase II. Hypertension 1998; 32: 393-401.
17. Beeks E, Kessels AG, Kroon AA, Van der Klauw MM, De Leeuw PW: Genetic predisposition to salt-sensitivity: a systematic review. J Hypertens 2004; 22: 1243-1249.
18. Province MA, Arnett DK, Hunt SC, et al, for the Hyper-GEN Group: Association between the alpha-adducin gene and hypertension in the HyperGen Study. Am J Hypertens 2000; 13: 710-718.
19. Larson N, Hutchinson R, Boerwinkle E: Lack of association of 3 functional gene variants with hypertension in African Americans. Hypertension 2000; 35: 1297-1300.
20. Matsubara M, Sato T, Nishimura T, et al: CYP11B2 polymorphisms and home blood pressure in a population-based cohort in Japanese: the Ohasama study. Hypertens Res 2004; 27: 1-6.
21. Shioji K, Kokubo Y, Mannami T, et al: Association between hypertension and the alpha-adducin, beta1-adrenoreceptor, and G-protein beta3 subunit genes in the Japanese population; the Suita study. Hypertens Res 2004; 27: 31-37.
22. Tanaka T, Okamura T, Miura K, et al: A simple method to estimate populational 24-h urinary sodium and potassium excretion using a casual urine specimen. J Hum Hypertens 2002; 16: 97-103.