Angiotensinogen M235T variant and salt sensitivity in young normotensive caucasians

Journal of Hypertension

Volumn 17, Issue 4, 1999, Pages 475-479

  Schorr, Ulrike ^a   Blaschke, Klaus ^a   Beige, Joachim ^a   Distler, Armin ^a   Sharma, Arya M ^a,b  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

Diet; Genetics; Hypertension; Salt sensitivity; Sodium restricted

Indexed keywords

ANGIOTENSINOGEN; SODIUM CHLORIDE;

ADULT; ARTICLE; BLOOD LEVEL; BLOOD PRESSURE; FAMILY HISTORY; GENOTYPE; HUMAN; HUMAN EXPERIMENT; HYPERTENSION; MALE; NORMAL HUMAN; POINT MUTATION; PRIORITY JOURNAL; SODIUM RESTRICTION;

EID: 0033033215     PISSN: 02636352     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004872-199917040-00004     Document Type: Article

References (35)

1. 1 Sealey J, Laragh JH. The renin-angiotensin-aldosterone system for normal regulation of blood pressure and sodium and potassium homeostasis. In: Laragh JH, Brenner BM (editors): Hypertension: pathophysiology, diagnosis and management. New York: Raven; 1990. pp 1287-1318.
2. 2 Inoue I, Nakajima T, Williams CS, Quackenbush J, Puryear R, Powers M, et al. A nucleotide substitution in the promoter of human angiotensinogen is associated with essential hypertension and affects basal transcription in vitro. J Clin Invest 1997; 99:1786-1797.
3. 3 Jeunemaitre X, Soubrier F, Kotelevtsev YV, Lifton RP, Williams CS, Charru A, et al. Molecular basis of human hypertension: role of angiotensinogen. Cell 1992; 71:169-180.
4. 4 Schunkert H, Hense HW, Gimenez-Roqueplo AP, Stieber J, Keil U, Riegger GAJ, et al. The angiotensinogen T235 variant and the use of antihypertensive drugs in a population-based cohort. Hypertension 1997; 29:628-633.
5. 5 Jeunemaitre X, Charru A, Chatellier G, Dumont C, Sassano P, Soubrier F, et al. M235T variant of the human angiotensinogen gene in unselected hypertensive patients. J Hypertens 1993; 11 (Suppl 5):S80-S81.
6. 6 Hata A, Namikawa C, Sasaki M, Sato K, Nakamura T, Tamura K, et al. Angiotensinogen as a risk factor for essential hypertension in Japan. J Clin Invest 1994; 93:1285-1287.
7. 7 Iwai N, Shimoike H, Ohmichi N, Kinoshita M. Angiotensinogen gene and blood pressure in the Japanese population. Hypertension 1995; 25:688-693.
8. 8 Hopkins PN, Lifton RP, Hollenberg NK, Jeunemaitre X, Hallouin MC, Skuppin J, et al. Blunted renal vascular response to angiotensin II is associated with a common variant of the angiotensinogen gene and obesity. J Hypertens 1996; 14:199-207.
9. 9 Weinberger MH. Salt sensitive human hypertension. Endocr Res 1991; 17:43-51.
10. 10 Weinberger MH. Salt sensitivity of blood pressure in humans. Hypertension 1996; 27:481-490.
11. 11 Sharma AM. Salt sensitivity as a phenotype for genetic studies of human hypertension. Nephrol Dial Transplant 1996; 11:927-929.
12. 12 Sharma AM, Schattenfroh S, Thiede HM, Oelkers W, Distler A. Effects of sodium salts on pressor reactivity in salt-sensitive men. Hypertension 1992; 19:541-548.
13. 13 Schorr U, Turan S, Distler A, Sharma AM. Relationship between ambulatory and resting blood pressure responses to dietary salt restriction in normotensive men. J Hypertens 1997; 15:845-849.
14. 14 Intersalt: an international study of electrolyte excretion and blood pressure. Results for 24 hour urinary sodium and potassium excretion. Intersalt Cooperative Research Group. BMJ 1988; 297:319-328.
15. 15 Sharma AM, Schorr U, Cetto C, Distler A. Dietary versus intravenous salt loading for the assessment of salt sensitivity in normotensive men. Am J Hypertens 1994; 7:1070-1075.
16. 16 Sharma AM, Cetto C, Schorr U, Spies K-P, Distler A. Renal acid-base excretion in normotensive salt-sensitive humans. Hypertension 1993; 22:884-890.
17. 17 Sharma AM, Schorr U, Distler A. Insulin resistance in young salt-sensitive normotensive subjects. Hypertension 1993; 21:273-279.
18. 18 Skrabal F, Herholz H, Neumayr M, Hamberger L, Ledochowski M, Sporer H, et al. Salt sensitivity in humans is linked to enhanced sympathetic responsiveness and to enhanced proximal tubular reabsorption. Hypertension 1984; 6:152-158.
19. 19 Skrabal F, Kotanko P, Meister B, Doll P, Gruber G. Up-regulation of alpha 2 adrenoceptors and down-regulation of beta 2 adrenoceptors by high-salt diet in normotensive men: enhanced up-regulation of operative (alpha 2 : beta 2) adrenoceptor ratio predicts salt sensitivity. J Hypertens 1986; 4 (Suppl 9):S196-S199.
20. 20 Blümel A, Oelkers W. Measurement of human plasma renin substrate concentration by angiotensin I radioimmunoassay: a discussion of methodical problems. Z Klin Chem Klin Biochem 1974; 12:453-458.
21. 21 Schorr U, Blaschke K, Turan S, Distler A, Sharma AM. Relationship between angiotensinogen, leptin, and blood pressure in young normotensive men. J Hypertens 1998; 16:1475-1480.
22. 22 Beige J, Zilch O, Hohenbleicher H, Ringel J, Kunz R, Distler A, et al. Genetic variants of the renin - angiotensin system and ambulatory blood pressure in essential hypertension. J Hypertens 1997; 15:503-508.
23. 23 Kunz R, Kreutz R, Beige J, Distler A, Sharma AM. Association between the angiotensinogen 235T-variant and essential hypertension in whites: a systematic review and methodological appraisal. Hypertension 1997; 30:1331-1337.
24. 24 Williams GH, Hollenberg NK. Non-modulating hypertension: a subset of sodium-sensitive hypertension. Hypertension 1991 ; 17 (Suppl 1):181-185.
25. 25 Seely EW, Moore TJ, Rogacz S, Gordon MS, Gleason RE, Hollenberg NK, et al. Angiotensin-mediated renin suppression is altered in non-modulating hypertension. Hypertension 1989; 13:31-37.
26. 26 Hunt SC, Cook NR, Oberman A, Cutler JA, Hennekens CH, Allender PC, et at. Angiotensinogen genotype, sodium reduction, weight loss, and prevention of hypertension: trials of hypertension prevention, Phase II. Hypertension 1998; 32:393-401.
27. 27 Hingorani AD, Sharma P, Jia HY, Hopper R, Brown MJ. Blood pressure and the M235T polymorphism of the angiotensinogen gene. Hypertension 1996; 28:907-911.
28. 28 Bigda J, Narkiewicz K, Chrostowska M, Winnicki M, Szczech R, Pawlowski R, et al. No effect of genetic variation at the angiotensinogen locus on ambulatory blood pressure level in normotensive subjects. Am J Hypertens 1997; 10:692-695.
29. 29 Schmidt S, Sharma AM, Zilch O, Beige J, Walla Friedel M, Ganten D, et al. Association of M235T variant of the angiotensinogen gene with familial hypertension of early onset. Nephrol Dial Transplant 1995; 10:1145-1148.
30. 30 Elliott P, Stamler J, Nichols R, Dyer AR, Stamler R, Kesteloot H, et al. Intersalt revisited: further analyses of 24 hour sodium excretion and blood pressure within and across populations. BMJ 1996; 312:1249-1253.
31. 31 Weinberger MH, Fineberg NS. Sodium and volume sensitivity of blood pressure: age and pressure change over time. Hypertension 1991 ; 18:67-71.
32. 32 Ummenhofer C, Kluthe R. Definition of 'salt sensitivity'. Dtsch Med Wochenschr 1994; 119:49-57.
33. 33 Sharma AM, Schattenfroh S, Kribben A, Distler A. Reliability of salt-sensitivity testing in normotensive subjects. Klin Wochenschr 1989; 67:632-634.
34. 34 Overlack A, Ruppert M, Kolloch R, Göbel B, Kraft K, Diehl J, et al. Divergent hemodynamic and hormonal responses to varying salt intake in normotensive subjects. Hypertension 1993; 22:331-338.
35. 35 Weinberger MH. Is salt-sensitivity of blood pressure a reproducible phenomenon? J Hypertens 1996; 14:1461-1462.