-
1
-
-
1442274703
-
Cdc42: New roads to travel
-
Cerione RA. Cdc42: New roads to travel. Trends Cell Biol 2004; 14:127-32.
-
(2004)
Trends Cell Biol
, vol.14
, pp. 127-132
-
-
Cerione, R.A.1
-
2
-
-
0035313804
-
Multiple roles for Cdc42 in cell regulation
-
Erickson JW, Cerione RA. Multiple roles for Cdc42 in cell regulation. Curr Opin Cell Biol 2001; 13:153-7.
-
(2001)
Curr Opin Cell Biol
, vol.13
, pp. 153-157
-
-
Erickson, J.W.1
Cerione, R.A.2
-
3
-
-
2342432240
-
Cdc42 - The centre of polarity
-
Etienne-Manneville S. Cdc42 - the centre of polarity. J Cell Sci 2004; 117:1291-300.
-
(2004)
J Cell Sci
, vol.117
, pp. 1291-1300
-
-
Etienne-Manneville, S.1
-
4
-
-
0027732538
-
Proteins regulating Ras and its relatives
-
Boguski MS, McCormick F. Proteins regulating Ras and its relatives. Nature 1993; 366:643-54.
-
(1993)
Nature
, vol.366
, pp. 643-654
-
-
Boguski, M.S.1
McCormick, F.2
-
6
-
-
0035668525
-
Dbl family guanine nucleotide exchange factors
-
Zheng Y. Dbl family guanine nucleotide exchange factors. Trends Biochem Sci 2001; 26:724-32.
-
(2001)
Trends Biochem Sci
, vol.26
, pp. 724-732
-
-
Zheng, Y.1
-
7
-
-
0034213327
-
Rho GTPases and their effector proteins
-
Bishop AL, Hall A. Rho GTPases and their effector proteins. Biochem J 2000; 348:241-55.
-
(2000)
Biochem J
, vol.348
, pp. 241-255
-
-
Bishop, A.L.1
Hall, A.2
-
8
-
-
0036181428
-
The evolutionary history of effectors downstream of Cdc42 and Rac
-
REVIEWS0002
-
Cotteret S, Chernoff J. The evolutionary history of effectors downstream of Cdc42 and Rac. Genome Biol 2002; 3:(REVIEWS0002).
-
(2002)
Genome Biol
, vol.3
-
-
Cotteret, S.1
Chernoff, J.2
-
9
-
-
0007051410
-
Identification of effector residues and a neutralizing epitope of Ha-ras-encoded p21
-
USA
-
Sigal IS, Gibbs JB, D'Alonzo JS, Scolnick EM. Identification of effector residues and a neutralizing epitope of Ha-ras-encoded p21. Proc Natl Acad Sci USA 1986; 83:4725-9.
-
(1986)
Proc Natl Acad Sci
, vol.83
, pp. 4725-4729
-
-
Sigal, I.S.1
Gibbs, J.B.2
D'Alonzo, J.S.3
Scolnick, E.M.4
-
10
-
-
0028903247
-
An essential role for Rac in Ras transformation
-
Qiu RG, Chen J, Kirn D, McCormick F, Symons M. An essential role for Rac in Ras transformation. Nature 1995; 374:457-9.
-
(1995)
Nature
, vol.374
, pp. 457-459
-
-
Qiu, R.G.1
Chen, J.2
Kirn, D.3
McCormick, F.4
Symons, M.5
-
11
-
-
0030992814
-
Cdc42 regulates anchorage-independent growth and is necessary for Ras transformation
-
Qiu RG, Abo A, McCormick F, Symons M. Cdc42 regulates anchorage-independent growth and is necessary for Ras transformation. Mol Cell Biol 1997; 17:3449-58.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 3449-3458
-
-
Qiu, R.G.1
Abo, A.2
McCormick, F.3
Symons, M.4
-
13
-
-
0028800305
-
Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation
-
Khosravi-Far R, Solski PA, Clark GJ, Kinch MS, Der CJ. Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation. Mol Cell Biol 1995; 15:6443-53.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 6443-6453
-
-
Khosravi-Far, R.1
Solski, P.A.2
Clark, G.J.3
Kinch, M.S.4
Der, C.J.5
-
14
-
-
0026002058
-
p21 with a phenylalanine 28 - leucine mutation reacts normally with the GTPase activating protein GAP but nevertheless has transforming properties
-
Reinstein J, Schlichting I, Frech M, Goody RS, Wittinghofer A. p21 with a phenylalanine 28 - leucine mutation reacts normally with the GTPase activating protein GAP but nevertheless has transforming properties. J Biol Chem 1991; 266:17700-6.
-
(1991)
J Biol Chem
, vol.266
, pp. 17700-17706
-
-
Reinstein, J.1
Schlichting, I.2
Frech, M.3
Goody, R.S.4
Wittinghofer, A.5
-
15
-
-
0031260578
-
A novel Cdc42Hs mutant induces cellular transformation
-
Lin R, Bagrodia S, Cerione R, Manor D. A novel Cdc42Hs mutant induces cellular transformation. Curr Biol 1997; 7:794-7.
-
(1997)
Curr Biol
, vol.7
, pp. 794-797
-
-
Lin, R.1
Bagrodia, S.2
Cerione, R.3
Manor, D.4
-
16
-
-
0033551698
-
Specific contributions of the small GTPases Rho, Rac, and Cdc42 to Dbl transformation
-
Lin R, Cerione RA, Manor D. Specific contributions of the small GTPases Rho, Rac, and Cdc42 to Dbl transformation. J Biol Chem 1999; 274:23633-41.
-
(1999)
J Biol Chem
, vol.274
, pp. 23633-23641
-
-
Lin, R.1
Cerione, R.A.2
Manor, D.3
-
17
-
-
4444341881
-
Distinct roles for JNK1 and JNK2 in regulating JNK activity and c-Jun-dependent cell proliferation
-
Sabapathy K, Hochedlinger K, Nam SY, Bauer A, Karin M, Wagner EF. Distinct roles for JNK1 and JNK2 in regulating JNK activity and c-Jun-dependent cell proliferation. Mol Cell 2004; 15:713-725.
-
(2004)
Mol Cell
, vol.15
, pp. 713-725
-
-
Sabapathy, K.1
Hochedlinger, K.2
Nam, S.Y.3
Bauer, A.4
Karin, M.5
Wagner, E.F.6
-
18
-
-
0024121513
-
The predicted DBL oncogene product defines a distinct class of transforming proteins
-
USA
-
Eva A, Vecchio G, Rao CD, Tronick SR, Aaronson SA. The predicted DBL oncogene product defines a distinct class of transforming proteins. Proc Natl Acad Sci USA 1988; 85:2061-5.
-
(1988)
Proc Natl Acad Sci
, vol.85
, pp. 2061-2065
-
-
Eva, A.1
Vecchio, G.2
Rao, C.D.3
Tronick, S.R.4
Aaronson, S.A.5
-
19
-
-
0026114849
-
Mechanism of Activation of the vav Proto-Oncogene
-
Coppola J, Bryant S, Koda T, Conway D and Barbacid M. Mechanism of Activation of the vav Proto-Oncogene. Cell Growth & Differentiation 1991; 2:95-105.
-
(1991)
Cell Growth & Differentiation
, vol.2
, pp. 95-105
-
-
Coppola, J.1
Bryant, S.2
Koda, T.3
Conway, D.4
Barbacid, M.5
-
20
-
-
0027972531
-
Novel human oncogene lbc detected by transfection with distinct homology regions to signal transduction products
-
Toksoz D, Williams DA. Novel human oncogene lbc detected by transfection with distinct homology regions to signal transduction products. Oncogene 1994; 9:621-8.
-
(1994)
Oncogene
, vol.9
, pp. 621-628
-
-
Toksoz, D.1
Williams, D.A.2
-
21
-
-
0022368305
-
Specific growth response of ras-transformed embryo fibroblasts to tumour promoters
-
Dotto GP, Parada LF, Weinberg RA. Specific growth response of ras-transformed embryo fibroblasts to tumour promoters. Nature 1985; 318:472-5.
-
(1985)
Nature
, vol.318
, pp. 472-475
-
-
Dotto, G.P.1
Parada, L.F.2
Weinberg, R.A.3
-
22
-
-
0025320158
-
EGF receptor and erbB-2 tyrosine kinase domains confer cell specificity for mitogenic signaling
-
Di Fiore PP, Segatto O, Taylor WG, Aaronson SA, Pierce JH. EGF receptor and erbB-2 tyrosine kinase domains confer cell specificity for mitogenic signaling. Science 1990; 248:79-83.
-
(1990)
Science
, vol.248
, pp. 79-83
-
-
Di Fiore, P.P.1
Segatto, O.2
Taylor, W.G.3
Aaronson, S.A.4
Pierce, J.H.5
-
23
-
-
0026806540
-
Five PDGF B amino acid substitutions convert PDGF a to a PDGF B-like transforming molecule
-
LaRochelle WJ, Pierce JH, May-Siroff M, Giese N, Aaronson SA. Five PDGF B amino acid substitutions convert PDGF A to a PDGF B-like transforming molecule. J Biol Chem 1992; 267:17074-7.
-
(1992)
J Biol Chem
, vol.267
, pp. 17074-17077
-
-
LaRochelle, W.J.1
Pierce, J.H.2
May-Siroff, M.3
Giese, N.4
Aaronson, S.A.5
-
24
-
-
0033520458
-
Integration of Rac-dependent regulation of cyclin D1 transcription through a nuclear factor-kappaB-dependent pathway
-
Joyce D, Bouzahzah B, Fu M, Albanese C, D'Amico M, Steer J, Klein JU, Lee RJ, Segall JE, Westwick JK, Der CJ, Pestell RG. Integration of Rac-dependent regulation of cyclin D1 transcription through a nuclear factor-kappaB-dependent pathway. J Biol Chem 1999; 274:25245-9.
-
(1999)
J Biol Chem
, vol.274
, pp. 25245-25249
-
-
Joyce, D.1
Bouzahzah, B.2
Fu, M.3
Albanese, C.4
D'Amico, M.5
Steer, J.6
Klein, J.U.7
Lee, R.J.8
Segall, J.E.9
Westwick, J.K.10
Der, C.J.11
Pestell, R.G.12
-
25
-
-
0000153275
-
Transformation activity of Cdc42 requires a region unique to Rho-related proteins
-
Wu WJ, Lin R, Cerione RA, Manor D. Transformation activity of Cdc42 requires a region unique to Rho-related proteins. J Biol Chem 1998; 273:16655-8.
-
(1998)
J Biol Chem
, vol.273
, pp. 16655-16658
-
-
Wu, W.J.1
Lin, R.2
Cerione, R.A.3
Manor, D.4
-
26
-
-
0025758833
-
A region of proto-dbl essential for its transforming activity shows sequence similarity to a yeast cell cycle gene, CDC24, and the human breakpoint cluster gene, bcr
-
Ron D, Zannini M, Lewis M, Wickner RB, Hunt LT, Graziani G, Tronick SR, Aaronson SA, Eva A. A region of proto-dbl essential for its transforming activity shows sequence similarity to a yeast cell cycle gene, CDC24, and the human breakpoint cluster gene, bcr. New Biol 1991; 3:372-9.
-
(1991)
New Biol
, vol.3
, pp. 372-379
-
-
Ron, D.1
Zannini, M.2
Lewis, M.3
Wickner, R.B.4
Hunt, L.T.5
Graziani, G.6
Tronick, S.R.7
Aaronson, S.A.8
Eva, A.9
-
27
-
-
0027958423
-
Cellular transformation and guanine nucleotide exchange activity are catalyzed by a common domain on the dbl oncogene product
-
Hart MJ, Eva A, Zangrilli D, Aaronson SA, Evans T, Cerione RA, Zheng Y. Cellular transformation and guanine nucleotide exchange activity are catalyzed by a common domain on the dbl oncogene product. J Biol Chem 1994; 269:62-5.
-
(1994)
J Biol Chem
, vol.269
, pp. 62-65
-
-
Hart, M.J.1
Eva, A.2
Zangrilli, D.3
Aaronson, S.A.4
Evans, T.5
Cerione, R.A.6
Zheng, Y.7
-
28
-
-
0028967665
-
Direct involvement of the small GTP-binding protein Rho in lbc oncogene function
-
Zheng Y, Olson MF, Hall A, Cerione RA, Toksoz D. Direct involvement of the small GTP-binding protein Rho in lbc oncogene function. J Biol Chem 1995; 270:9031-4.
-
(1995)
J Biol Chem
, vol.270
, pp. 9031-9034
-
-
Zheng, Y.1
Olson, M.F.2
Hall, A.3
Cerione, R.A.4
Toksoz, D.5
-
29
-
-
20744453511
-
Cdc42 and Ras cooperate to mediate cellular transformation by intersectin-L
-
Wang JB, Wu WJ, Cerione RA. Cdc42 and Ras cooperate to mediate cellular transformation by intersectin-L. J Biol Chem 2005; 280:22883-91.
-
(2005)
J Biol Chem
, vol.280
, pp. 22883-22891
-
-
Wang, J.B.1
Wu, W.J.2
Cerione, R.A.3
-
30
-
-
0141426629
-
Activated Cdc42 sequesters c-Cbl and prevents EGF receptor degradation
-
Wu WJ, Tu S, Cerione RA. Activated Cdc42 sequesters c-Cbl and prevents EGF receptor degradation. Cell 2003; 114:715-25.
-
(2003)
Cell
, vol.114
, pp. 715-725
-
-
Wu, W.J.1
Tu, S.2
Cerione, R.A.3
-
31
-
-
0028820587
-
Rho family GTPases regulate p38 mitogen-activated protein kinase through the downstream mediator Pak1
-
Zhang S, Han J, Sells MA, Chernoff J, Knaus UG, Ulevitch RJ, Bokoch GM. Rho family GTPases regulate p38 mitogen-activated protein kinase through the downstream mediator Pak1. J Biol Chem 1995; 270:23934-6.
-
(1995)
J Biol Chem
, vol.270
, pp. 23934-23936
-
-
Zhang, S.1
Han, J.2
Sells, M.A.3
Chernoff, J.4
Knaus, U.G.5
Ulevitch, R.J.6
Bokoch, G.M.7
-
32
-
-
0029055812
-
The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway
-
Coso OA, Chiariello M, Yu JC, Teramoto H, Crespo P, Xu N, Miki T, Gutkind JS. The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway. Cell 1995; 81:1137-46.
-
(1995)
Cell
, vol.81
, pp. 1137-1146
-
-
Coso, O.A.1
Chiariello, M.2
Yu, J.C.3
Teramoto, H.4
Crespo, P.5
Xu, N.6
Miki, T.7
Gutkind, J.S.8
-
33
-
-
0028875683
-
Cdc42 and PAK-mediated signaling leads to Jun kinase and p38 mitogen-activated protein kinase activation
-
Bagrodia S, Derijard B, Davis RJ, Cerione RA. Cdc42 and PAK-mediated signaling leads to Jun kinase and p38 mitogen-activated protein kinase activation. J Biol Chem 1995; 270:27995-8.
-
(1995)
J Biol Chem
, vol.270
, pp. 27995-27998
-
-
Bagrodia, S.1
Derijard, B.2
Davis, R.J.3
Cerione, R.A.4
-
34
-
-
0029070887
-
Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs
-
Minden A, Lin A, Claret FX, Abo A, Karin M. Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs. Cell 1995; 81:1147-57.
-
(1995)
Cell
, vol.81
, pp. 1147-1157
-
-
Minden, A.1
Lin, A.2
Claret, F.X.3
Abo, A.4
Karin, M.5
-
35
-
-
0028329953
-
JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain
-
Derijard B, Hibi M, Wu IH, Barrett T, Su B, Deng T, Karin M, Davis RJ. JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain. Cell 1994; 76:1025-37.
-
(1994)
Cell
, vol.76
, pp. 1025-1037
-
-
Derijard, B.1
Hibi, M.2
Wu, I.H.3
Barrett, T.4
Su, B.5
Deng, T.6
Karin, M.7
Davis, R.J.8
-
36
-
-
0028905076
-
Transcription factor ATF2 regulation by the JNK signal transduction pathway
-
Gupta S, Campbell D, Derijard B, Davis RJ. Transcription factor ATF2 regulation by the JNK signal transduction pathway. Science 1995; 267:389-93.
-
(1995)
Science
, vol.267
, pp. 389-393
-
-
Gupta, S.1
Campbell, D.2
Derijard, B.3
Davis, R.J.4
-
37
-
-
0028609209
-
JNK2 contains a specificity-determining region responsible for efficient c-Jun binding and phosphorylation
-
Kallunki T, Su B, Tsigelny I, Sluss HK, Derijard B, Moore G, Davis R, Karin M. JNK2 contains a specificity-determining region responsible for efficient c-Jun binding and phosphorylation. Genes Dev 1994; 8:2996-3007.
-
(1994)
Genes Dev
, vol.8
, pp. 2996-3007
-
-
Kallunki, T.1
Su, B.2
Tsigelny, I.3
Sluss, H.K.4
Derijard, B.5
Moore, G.6
Davis, R.7
Karin, M.8
-
38
-
-
17144371848
-
JNK2: A negative regulator of cellular proliferation
-
Sabapathy K, Wagner EF. JNK2: A negative regulator of cellular proliferation. Cell Cycle 2004; 3:1520-3.
-
(2004)
Cell Cycle
, vol.3
, pp. 1520-1523
-
-
Sabapathy, K.1
Wagner, E.F.2
-
40
-
-
0031034469
-
Activation of the nuclear factor-kappaB by Rho, CDC42, and Rac-1 proteins
-
Perona R, Montaner S, Saniger L, Sanchez-Perez I, Bravo R, Lacal JC. Activation of the nuclear factor-kappaB by Rho, CDC42, and Rac-1 proteins. Genes Dev 1997; 11:463-75.
-
(1997)
Genes Dev
, vol.11
, pp. 463-475
-
-
Perona, R.1
Montaner, S.2
Saniger, L.3
Sanchez-Perez, I.4
Bravo, R.5
Lacal, J.C.6
-
41
-
-
0032557526
-
Multiple signalling pathways lead to the activation of the nuclear factor kappaB by the Rho family of GTPases
-
Montaner S, Perona R, Saniger L, Lacal JC. Multiple signalling pathways lead to the activation of the nuclear factor kappaB by the Rho family of GTPases. J Biol Chem 1998; 273:12779-85.
-
(1998)
J Biol Chem
, vol.273
, pp. 12779-12785
-
-
Montaner, S.1
Perona, R.2
Saniger, L.3
Lacal, J.C.4
-
42
-
-
0032479167
-
Transforming potential of Dbl family proteins correlates with transcription from the cyclin D1 promoter but not with activation of Jun NH2-terminal kinase, p38/Mpk2, serum response factor, or c-Jun
-
Westwick JK, Lee RJ, Lambert QT, Symons M, Pestell RG, Der CJ, Whitehead IP. Transforming potential of Dbl family proteins correlates with transcription from the cyclin D1 promoter but not with activation of Jun NH2-terminal kinase, p38/Mpk2, serum response factor, or c-Jun. J Biol Chem 1998; 273:16739-47.
-
(1998)
J Biol Chem
, vol.273
, pp. 16739-16747
-
-
Westwick, J.K.1
Lee, R.J.2
Lambert, Q.T.3
Symons, M.4
Pestell, R.G.5
Der, C.J.6
Whitehead, I.P.7
-
43
-
-
0031026132
-
Rac regulation of transformation, gene expression, and actin organization by multiple, PAK-independent pathways
-
Westwick JK, Lambert QT, Clark GJ, Symons, Van Aelst L, Pestell RG, Der C.J. Rac regulation of transformation, gene expression, and actin organization by multiple, PAK-independent pathways. Mol Cell Biol 1997; 17:1324-35.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 1324-1335
-
-
Westwick, J.K.1
Lambert, Q.T.2
Clark, G.J.3
Symons4
Van Aelst, L.5
Pestell, R.G.6
Der, C.J.7
-
44
-
-
0032695889
-
Dependence of Dbl and Dbs transformation on MEK and NF-kappaB activation
-
Whitehead IP, Lambert QT, Glaven JA, Abe K, Rossman KL, Mahon GM et al. Dependence of Dbl and Dbs transformation on MEK and NF-kappaB activation. Mol Cell Biol 1999; 19:7759-70.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 7759-7770
-
-
Whitehead, I.P.1
Lambert, Q.T.2
Glaven, J.A.3
Abe, K.4
Rossman, K.L.5
Mahon, G.M.6
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