Synthesis of a novel biotin-tagged photoaffinity probe for VEGF receptor tyrosine kinases

Bioorganic and Medicinal Chemistry Letters

Volumn 16, Issue 1, 2006, Pages 129-133

  Han, Sun Young ^a   Park, Seok Soon ^a   Lee, Woo Ghil ^a   Min, Yong Ki ^a   Kim, Bum Tae ^a  

^a Korea Research Institute of Chemical Technology   (South Korea)

Author keywords

Biotin tagged photoaffinity probe; Inhibitor; Ligand protein interactions; Vascular endothelial growth factor receptors

Indexed keywords

BIOTIN; TYROSINE KINASE RECEPTOR; VASCULOTROPIN INHIBITOR; VASCULOTROPIN RECEPTOR 2;

ARTICLE; CONTROLLED STUDY; DRUG INHIBITION; DRUG POTENCY; DRUG PROTEIN BINDING; ENDOTHELIUM CELL; ENZYME INHIBITION; EVALUATION; HUMAN; HUMAN CELL; IC 50; LIGAND BINDING; MECHANICAL PROBE; PHOTOAFFINITY LABELING; SYNTHESIS; UMBILICAL VEIN;

BIOTIN; CELL PROLIFERATION; CELLS, CULTURED; CHEMISTRY, PHARMACEUTICAL; DRUG DESIGN; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; HUMANS; HYDROCARBONS, BROMINATED; INHIBITORY CONCENTRATION 50; LIGANDS; LIGHT; MODELS, CHEMICAL; PROTEIN BINDING; QUINAZOLINES; RECEPTORS, VASCULAR ENDOTHELIAL GROWTH FACTOR; SPECTROPHOTOMETRY, ULTRAVIOLET; THIAZOLES; TIME FACTORS; ULTRAVIOLET RAYS; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2;

EID: 27744519286     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.09.036     Document Type: Article

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