The nucleotide sequence and a first generation gene transfer vector of species B human adenovirus serotype 3

Virology

Volumn 343, Issue 2, 2005, Pages 283-298

  Sirena, Dominique ^a   Ruzsics, Zsolt ^b   Schaffner, Walter ^a   Greber, Urs F ^a   Hemmi, Silvio ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b UNIVERSITY OF MUNICH   (Germany)

Author keywords

Bacterial artificial chromosome; Gene transfer vector; Human adenovirus type 3; Species B1 adenovirus

Indexed keywords

E1A PROTEIN; E1B PROTEIN; MEMBRANE COFACTOR PROTEIN; NUCLEOTIDE; PROTEIN SUBUNIT; RECOMBINANT PROTEIN; TRANSCRIPTION FACTOR E2; TRANSCRIPTION FACTOR E3; TRANSCRIPTION FACTOR E4; UNCLASSIFIED DRUG; VIRUS DNA; VIRUS NUCLEOPROTEIN; VIRUS PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; BACTERIAL ARTIFICIAL CHROMOSOME; DNA SEQUENCE; GENE DELETION; GENE TRANSFER; GENE VECTOR; GENETIC ANALYSIS; GENOME ANALYSIS; HUMAN ADENOVIRUS; HYPOTHESIS; NUCLEIC ACID ANALYSIS; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SEROTYPING; SPECIES; SPECIES IDENTIFICATION; VIRAL GENETICS; VIRUS GENE; VIRUS ISOLATION; VIRUS TYPING; VIRUS VIRULENCE;

ADENOVIRUSES, HUMAN; ANIMALS; ANTIGENS, CD46; BASE SEQUENCE; CELL LINE; CHROMOSOMES, ARTIFICIAL, BACTERIAL; CRICETINAE; DNA, VIRAL; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; GENOME, VIRAL; GREEN FLUORESCENT PROTEINS; HUMANS; MOLECULAR SEQUENCE DATA; OPEN READING FRAMES; RECOMBINANT PROTEINS; SEROTYPING; TRANSDUCTION, GENETIC; VIRAL PROTEINS; VIRULENCE;

ADENOVIRIDAE; BACTERIA (MICROORGANISMS); DNA VIRUSES; HUMAN ADENOVIRUS; HUMAN ADENOVIRUS TYPE 3; RODENTIA;

EID: 27744490827     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2005.08.024     Document Type: Article

References (112)

1. K. Abrahamsen, H.L. Kong, A. Mastrangeli, D. Brough, A. Lizonova, R.G. Crystal, and E. Falck-Pedersen Construction of an adenovirus type 7a E1A-vector J. Virol. 71 11 1997 8946 8951
2. T. Adrian, G. Wadell, J.C. Hierholzer, and R. Wigand DNA restriction analysis of adenovirus prototypes 1 to 41 Arch. Virol. 91 3-4 1986 277 290
3. F. Almazan, J.M. Gonzalez, Z. Penzes, A. Izeta, E. Calvo, J. Plana-Duran, and L. Enjuanes Engineering the largest RNA virus genome as an infectious bacterial artificial chromosome Proc. Natl. Acad. Sci. U.S.A. 97 10 2000 5516 5521
4. N. Avvakumov, M. Sahbegovic, Z. Zhang, M. Shuen, and J.S. Mymryk Analysis of DNA binding by the adenovirus type 5 E1A oncoprotein J. Gen. Virol. 83 Pt 3 2002 517 524
5. A. Bailey, and V. Mautner Phylogenetic relationships among adenovirus serotypes Virology 205 2 1994 438 452
6. J.M. Bergelson, J.A. Cunningham, G. Droguett, E.A. Kurt-Jones, A. Krithivas, J.S. Hong, M.S. Horwitz, R.L. Crowell, and R.W. Finberg Isolation of a common receptor for Coxsackie B viruses and adenoviruses 2 and 5 Science 275 5304 1997 1320 1323
7. J.L. Boyer, and G. Ketner Genetic analysis of a potential zinc-binding domain of the adenovirus E4 34k protein J. Biol. Chem. 275 20 2000 14969 14978
8. H.G. Burgert, and J.H. Blusch Immunomodulatory functions encoded by the E3 transcription unit of adenoviruses Virus Genes 21 1-2 2000 13 25
9. J. Carcamo, E. Maldonado, P. Cortes, M.H. Ahn, I. Ha, Y. Kasai, J. Flint, and D. Reinberg A TATA-like sequence located downstream of the transcription initiation site is required for expression of an RNA polymerase II transcribed gene Genes Dev. 4 9 1990 1611 1622
10. C. Chartier, E. Degryse, M. Gantzer, A. Dieterle, A. Pavirani, and M. Mehtali Efficient generation of recombinant adenovirus vectors by homologous recombination in Escherichia coli J. Virol. 70 7 1996 4805 4810
11. M. Chen, N. Mermod, and M.S. Horwitz Protein-protein interactions between adenovirus DNA polymerase and nuclear factor I mediate formation of the DNA replication preinitiation complex J. Biol. Chem. 265 30 1990 18634 18642
12. J. Chroboczek, F. Bieber, and B. Jacrot The sequence of the genome of adenovirus type 5 and its comparison with the genome of adenovirus type 2 Virology 186 1 1992 280 285
13. J.D. Cogan, S.N. Jones, R.K. Hall, and C. Tibbetts Functional diversity of E1A gene autoregulation among human adenoviruses J. Virol. 66 6 1992 3833 3845
14. B. Crimeen-Irwin, S. Ellis, D. Christiansen, M.J. Ludford-Menting, J. Milland, M. Lanteri, B.E. Loveland, D. Gerlier, and S.M. Russell Ligand binding determines whether CD46 is internalized by clathrin-coated pits or macropinocytosis J. Biol. Chem. 278 47 2003 46927 46937
15. R. Cuesta, Q. Xi, and R.J. Schneider Structural basis for competitive inhibition of eIF4G-Mnk1 interaction by the adenovirus 100-kilodalton protein J. Virol. 78 14 2004 7707 7716
16. S. Cusack Adenovirus complex structures Curr. Opin. Struct. Biol. 15 2 2005 237 243
17. A. Cuzange, J. Chroboczek, and B. Jacrot The penton base of human adenovirus type 3 has the RGD motif Gene 146 2 1994 257 259
18. K.A. Datsenko, and B.L. Wanner One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products Proc. Natl. Acad. Sci. U.S.A. 97 12 2000 6640 6645
19. C. Defer, M.T. Belin, M.L. Caillet-Boudin, and P. Boulanger Human adenovirus-host cell interactions: comparative study with members of subgroups B and C J. Virol. 64 8 1990 3661 3673
20. A.M. Di Guilmi, A. Barge, P. Kitts, E. Gout, and J. Chroboczek Human adenovirus serotype 3 (Ad3) and the Ad3 fiber protein bind to a 130-kDa membrane protein on HeLa cells Virus Res. 38 1 1995 71 81
21. R. Dijkema, B.M. Dekker, H. van Ormondt, A. de Waard, J. Maat, and H.W. Boyer Gene organization of the transforming region of weakly oncogenic adenovirus type 7: the E1a region Gene 12 3-4 1980 287 299
22. R. Dijkema, B.M. Dekker, and H. van Ormondt Gene organization of the transforming region of adenovirus type 7 DNA Gene 18 2 1982 143 156
23. B.A. Dudding, S.C. Wagner, J.A. Zeller, J.T. Gmelich, G.R. French, and F.H. Top Jr. Fatal pneumonia associated with adenovirus type 7 in three military trainees N. Engl. J. Med. 286 24 1972 1289 1292
24. J.A. Engler The nucleotide sequence of the polypeptide IX gene of human adenovirus type 3 Gene 13 4 1981 387 394
25. J.A. Engler, L.T. Chow, and T.R. Broker Sequences of human adenovirus Ad3 and Ad7 DNAs encoding the promoter and first leader segment of late RNAs Gene 13 2 1981 133 143
26. C.M. Fabry, M. Rosa-Calatrava, J.F. Conway, C. Zubieta, S. Cusack, R.W. Ruigrok, and G. Schoehn A quasi-atomic model of human adenovirus type 5 capsid EMBO J. 24 9 2005 1645 1654
27. F.J. Fallaux, O. Kranenburg, S.J. Cramer, A. Houweling, H. Van Ormondt, R.C. Hoeben, and A.J. Van Der Eb Characterization of 911: a new helper cell line for the titration and propagation of early region 1-deleted adenoviral vectors Hum. Gene Ther. 7 2 1996 215 222
28. S.P. Fessler, and C.S. Young The role of the L4 33K gene in adenovirus infection Virology 263 2 1999 507 516
29. C. Fleischli, S. Verhaag, M. Havenga, D. Sirena, W. Schaffner, R. Cattaneo, U.F. Greber, and S. Hemmi The distal short consensus repeats 1 and 2 of the membrane cofactor protein CD46 and their distance from the cell membrane determine productive entry of species B adenovirus serotype 35 J. Virol. 79 15 2005 10013 10022
30. K.K. Frese, S.S. Lee, D.L. Thomas, I.J. Latorre, R.S. Weiss, B.A. Glaunsinger, and R.T. Javier Selective PDZ protein-dependent stimulation of phosphatidylinositol 3-kinase by the adenovirus E4-ORF1 oncoprotein Oncogene 22 5 2003 710 721
31. A. Gaggar, D.M. Shayakhmetov, and A. Lieber CD46 is a cellular receptor for group B adenoviruses Nat. Med. 9 11 2003 1408 1412
32. J. Gall, A. Kass-Eisler, L. Leinwand, and E. Falck-Pedersen Adenovirus type 5 and 7 capsid chimera: fiber replacement alters receptor tropism without affecting primary immune neutralization epitopes J. Virol. 70 4 1996 2116 2123
33. W. Gao, P.D. Robbins, and A. Gambotto Human adenovirus type 35: nucleotide sequence and vector development Gene Ther. 10 23 2003 1941 1949
34. D. Gautheret, and A. Lambert Direct RNA motif definition and identification from multiple sequence alignments using secondary structure profiles J. Mol. Biol. 313 5 2001 1003 1011
35. U.F. Greber, P. Webster, J. Weber, and A. Helenius The role of the adenovirus protease on virus entry into cells EMBO J. 15 8 1996 1766 1777
36. S. Hardy, M. Kitamura, T. Harris-Stansil, Y. Dai, and M.L. Phipps Construction of adenovirus vectors through Cre-lox recombination J. Virol. 71 3 1997 1842 1849
37. M.J. Havenga, A.A. Lemckert, J.M. Grimbergen, R. Vogels, L.G. Huisman, D. Valerio, A. Bout, and P.H. Quax Improved adenovirus vectors for infection of cardiovascular tissues J. Virol. 75 7 2001 3335 3342
38. M.J. Havenga, A.A. Lemckert, O.J. Ophorst, M. van Meijer, W.T. Germeraad, J. Grimbergen, M.A. van Den Doel, R. Vogels, J. van Deutekom, A.A. Janson, J.D. de Bruijn, F. Uytdehaag, P.H. Quax, T. Logtenberg, M. Mehtali, and A. Bout Exploiting the natural diversity in adenovirus tropism for therapy and prevention of disease J. Virol. 76 9 2002 4612 4620
39. R.T. Hay, A. Freeman, I. Leith, A. Monaghan, and A. Webster Molecular interactions during adenovirus DNA replication Curr. Top. Microbiol. Immunol. 199 Pt 2 1995 31 48
40. S. Hemmi, R. Geertsen, A. Mezzacasa, I. Peter, and R. Dummer The presence of human coxsackievirus and adenovirus receptor is associated with efficient adenovirus-mediated transgene expression in human melanoma cell cultures Hum. Gene Ther. 9 16 1998 2363 2373
41. A. Heysen, P. Verwaerde, and J.C. D'Halluin Nucleotide sequence and regulation of the adenovirus type 3 E2A early promoter Virology 181 1 1991 241 250
42. M.M. Hitt, C.L. Addison, and F.L. Graham Human adenovirus vectors for gene transfer into mammalian cells Adv. Pharmacol. 40 1997 137 206
43. L. Holterman, R. Vogels, R. van der Vlugt, M. Sieuwerts, J. Grimbergen, J. Kaspers, E. Geelen, E. van der Helm, A. Lemckert, G. Gillissen, S. Verhaagh, J. Custers, D. Zuijdgeest, B. Berkhout, M. Bakker, P. Quax, J. Goudsmit, and M. Havenga Novel replication-incompetent vector derived from adenovirus type 11 (Ad11) for vaccination and gene therapy: low seroprevalence and non-cross-reactivity with Ad5 J. Virol. 78 23 2004 13207 13215
44. J.S. Hong, K.G. Mullis, and J.A. Engler Characterization of the early region 3 and fiber genes of Ad7 Virology 167 2 1988 545 553
45. M.S. Horwitz Function of adenovirus E3 proteins and their interactions with immunoregulatory cell proteins J. Gene Med. 6 Suppl 1 2004 S172 S183
46. A. Houde, and J.M. Weber Sequence of the human adenovirus type 3 protease Nucleic Acids Res. 16 23 1988 11374
47. J.T. Huang, and R.J. Schneider Adenovirus inhibition of cellular protein synthesis involves inactivation of cap-binding protein Cell 65 2 1991 271 280
48. R. Javier, K. Raska Jr., and T. Shenk Requirement for the adenovirus type 9 E4 region in production of mammary tumors Science 257 5074 1992 1267 1271
49. A.E. Kajon, W. Xu, and D.D. Erdman Sequence polymorphism in the E3 7.7K ORF of subspecies B1 human adenoviruses Virus Res. 107 1 2005 11 19
50. A. Kanerva, M. Wang, G.J. Bauerschmitz, J.T. Lam, R.A. Desmond, S.M. Bhoola, M.N. Barnes, R.D. Alvarez, G.P. Siegal, D.T. Curiel, and A. Hemminki Gene transfer to ovarian cancer versus normal tissues with fiber-modified adenoviruses Mol. Ther. 5 6 2002 695 704
51. A.H. Kidd, D. Garwicz, and M. Oberg Human and simian adenoviruses: phylogenetic inferences from analysis of VA RNA genes Virology 207 1 1995 32 45
52. J. Kitajewski, R.J. Schneider, B. Safer, S.M. Munemitsu, C.E. Samuel, B. Thimmappaya, and T. Shenk Adenovirus VAI RNA antagonizes the antiviral action of interferon by preventing activation of the interferon-induced eIF-2 alpha kinase Cell 45 2 1986 195 200
53. G.R. Kitchingman Sequence of the DNA-binding protein of a human subgroup E adenovirus (type 4): comparisons with subgroup A (type 12), subgroup B (type 7), and subgroup C (type 5) Virology 146 1 1985 90 101
54. S. Knaan-Shanzer, I. Van Der Velde, M.J. Havenga, A.A. Lemckert, A.A. De Vries, and D. Valerio Highly efficient targeted transduction of undifferentiated human hematopoietic cells by adenoviral vectors displaying fiber knobs of subgroup B Hum. Gene Ther. 12 16 2001 1989 2005
55. L.D. Kosturko, S.V. Sharnick, and C. Tibbetts Polar encapsidation of adenovirus DNA: cloning and DNA sequence of the left end of adenovirus type 3 J. Virol. 43 3 1982 1132 1137
56. Q.G. Li, and G. Wadell Comparison of 17 genome types of adenovirus type 3 identified among strains recovered from six continents J. Clin. Microbiol. 26 5 1988 1009 1015
57. M.D. Lubeck, A.R. Davis, M. Chengalvala, R.J. Natuk, J.E. Morin, K. Molnar-Kimber, B.B. Mason, B.M. Bhat, S. Mizutani, and P.P. Hung Immunogenicity and efficacy testing in chimpanzees of an oral hepatitis B vaccine based on live recombinant adenovirus Proc. Natl. Acad. Sci. U.S.A. 86 17 1989 6763 6767
58. W.F. Mangel, M.L. Baniecki, and W.J. McGrath Specific interactions of the adenovirus proteinase with the viral DNA, an 11-amino-acid viral peptide, and the cellular protein actin Cell. Mol. Life Sci. 60 11 2003 2347 2355
59. P. Mathias, T. Wickham, M. Moore, and G. Nemerow Multiple adenovirus serotypes use alpha v integrins for infection J. Virol. 68 10 1994 6811 6814
60. Y.F. Mei, J. Skog, K. Lindman, and G. Wadell Comparative analysis of the genome organization of human adenovirus 11, a member of the human adenovirus species B, and the commonly used human adenovirus 5 vector, a member of species C J. Gen. Virol. 84 Pt 8 2003 2061 2071
61. O. Meier, K. Boucke, S.V. Hammer, S. Keller, R.P. Stidwill, S. Hemmi, and U.F. Greber Adenovirus triggers macropinocytosis and endosomal leakage together with its clathrin-mediated uptake J. Cell Biol. 158 6 2002 1119 1131
62. O. Meier, M. Gastaldelli, K. Boucke, S. Hemmi, and U.F. Greber Early steps of clathrin-mediated endocytosis involved in phagosomal escape of Fcgamma receptor-targeted adenovirus J. Virol. 79 4 2005 2604 2613
63. O. Meier, and U.F. Greber Adenovirus endocytosis J. Gene Med. 5 6 2003 451 462
64. M. Messerle, I. Crnkovic, W. Hammerschmidt, H. Ziegler, and U.H. Koszinowski Cloning and mutagenesis of a herpesvirus genome as an infectious bacterial artificial chromosome Proc. Natl. Acad. Sci. U.S.A. 94 26 1997 14759 14763
65. H. Nagel, S. Maag, A. Tassis, F.O. Nestle, U.F. Greber, and S. Hemmi The alphavbeta5 integrin of hematopoietic and nonhematopoietic cells is a transduction receptor of RGD-4C fiber-modified adenoviruses Gene Ther. 10 19 2003 1643 1653
66. X. Nan, B. Peng, T.W. Hahn, E. Richardson, A. Lizonova, I. Kovesdi, and M. Robert-Guroff Development of an Ad7 cosmid system and generation of an Ad7deltaE1deltaE3HIV(MN) env/rev recombinant virus Gene Ther. 10 4 2003 326 336
67. R.J. Parks Adenovirus protein IX: a new look at an old protein Mol. Ther. 11 1 2005 19 25
68. P. Pring-Akerblom, F.E. Trijssenaar, and T. Adrian Sequence characterization and comparison of human adenovirus subgenus B and E hexons Virology 212 1 1995 232 236
69. A. Purkayastha, S.E. Ditty, J. Su, J. McGraw, T.L. Hadfield, C. Tibbetts, and D. Seto Genomic and bioinformatics analysis of HAdV-4, a human adenovirus causing acute respiratory disease: implications for gene therapy and vaccine vector development J. Virol. 79 4 2005 2559 2572
70. A. Purkayastha, J. Su, S. Carlisle, C. Tibbetts, and D. Seto Genomic and bioinformatics analysis of HAdV-7, a human adenovirus of species B1 that causes acute respiratory disease: implications for vector development in human gene therapy Virology 332 1 2005 114 129
71. D. Rea, M.J. Havenga, M. van Den Assem, R.P. Sutmuller, A. Lemckert, R.C. Hoeben, A. Bout, C.J. Melief, and R. Offringa Highly efficient transduction of human monocyte-derived dendritic cells with subgroup B fiber-modified adenovirus vectors enhances transgene-encoded antigen presentation to cytotoxic T cells J. Immunol. 166 8 2001 5236 5244
72. M.G. Reese, F.H. Eeckman, D. Kulp, and D. Haussler Improved splice site detection in Genie J. Comput. Biol. 4 3 1997 311 323
73. P.W. Roelvink, A. Lizonova, J.G. Lee, Y. Li, J.M. Bergelson, R.W. Finberg, D.E. Brough, I. Kovesdi, and T.J. Wickham The coxsackievirus-adenovirus receptor protein can function as a cellular attachment protein for adenovirus serotypes from subgroups A, C, D, E, and F J. Virol. 72 10 1998 7909 7915
74. M. Rosa-Calatrava, L. Grave, F. Puvion-Dutilleul, B. Chatton, and C. Kedinger Functional analysis of adenovirus protein IX identifies domains involved in capsid stability, transcriptional activity, and nuclear reorganization J. Virol. 75 15 2001 7131 7141
75. W.C. Russell Update on adenovirus and its vectors J. Gen. Virol. 81 Pt 11 2000 2573 2604
76. M.A. Ryan, G.C. Gray, B. Smith, J.A. McKeehan, A.W. Hawksworth, and M.D. Malasig Large epidemic of respiratory illness due to adenovirus types 7 and 3 in healthy young adults Clin. Infect. Dis. 34 5 2002 577 582
77. + cells by an adenovirus type 35 vector Gene Ther. 10 12 2003 1041 1048
78. C. San Martin, and R.M. Burnett Structural studies on adenoviruses Curr. Top. Microbiol. Immunol. 272 2003 57 94
79. H. Schmitz, R. Wigand, and W. Heinrich Worldwide epidemiology of human adenovirus infections Am. J. Epidemiol. 117 4 1983 455 466
80. A. Segerman, J.P. Atkinson, M. Marttila, V. Dennerquist, G. Wadell, and N. Arnberg Adenovirus type 11 uses CD46 as a cellular receptor J. Virol. 77 17 2003 9183 9191
81. P. Seshidhar Reddy, S. Ganesh, M.P. Limbach, T. Brann, A. Pinkstaff, M. Kaloss, M. Kaleko, and S. Connelly Development of adenovirus serotype 35 as a gene transfer vector Virology 311 2 2003 384 393
82. D.M. Shayakhmetov, T. Papayannopoulou, G. Stamatoyannopoulos, and A. Lieber Efficient gene transfer into human CD34(+) cells by a retargeted adenovirus vector J. Virol. 74 6 2000 2567 2583
83. T. Shenk Adenoviridae: the viruses and their replication B.N. Fields P.M. Howley D.E. Griffin Virology 4th ed. 2001 Lippincott-Raven Publisher Philadelphia 2265 2300
84. M. Shinagawa, and R. Padmanabhan Comparative sequence analysis of the inverted terminal repetitions from different adenoviruses Proc. Natl. Acad. Sci. U.S.A. 77 7 1980 3831 3835
85. C. Signas, G. Akusjarvi, and U. Pettersson Adenovirus 3 fiber polypeptide gene: implications for the structure of the fiber protein J. Virol. 53 2 1985 672 678
86. C. Signas, G. Akusjarvi, and U. Pettersson Region E3 of human adenoviruses; differences between the oncogenic adenovirus-3 and the non-oncogenic adenovirus-2 Gene 50 1-3 1986 173 184
87. D. Sirena, B. Lilienfeld, M. Eisenhut, S. Kalin, K. Boucke, R.R. Beerli, L. Vogt, C. Ruedl, M.F. Bachmann, U.F. Greber, and S. Hemmi The human membrane cofactor CD46 is a receptor for species B adenovirus serotype 3 J. Virol. 78 9 2004 4454 4462
88. T.A. Smith, N. Idamakanti, M.L. Rollence, J. Marshall-Neff, J. Kim, K. Mulgrew, G.R. Nemerow, M. Kaleko, and S.C. Stevenson Adenovirus serotype 5 fiber shaft influences in vivo gene transfer in mice Hum. Gene Ther. 14 8 2003 777 787
89. H. Stecher, D.M. Shayakhmetov, G. Stamatoyannopoulos, and A. Lieber A capsid-modified adenovirus vector devoid of all viral genes: assessment of transduction and toxicity in human hematopoietic cells Mol. Ther. 4 1 2001 36 44
90. S.C. Stevenson, M. Rollence, B. White, L. Weaver, and A. McClelland Human adenovirus serotypes 3 and 5 bind to two different cellular receptors via the fiber head domain J. Virol. 69 5 1995 2850 2857
91. S.C. Stevenson, M. Rollence, J. Marshall-Neff, and A. McClelland Selective targeting of human cells by a chimeric adenovirus vector containing a modified fiber protein J. Virol. 71 6 1997 4782 4790
92. D. Stone, A. Furthmann, V. Sandig, and A. Lieber The complete nucleotide sequence, genome organization, and origin of human adenovirus type 11 Virology 309 1 2003 152 165
93. D. Stone, S. Ni, Z.Y. Li, A. Gaggar, N. DiPaolo, Q. Feng, V. Sandig, and A. Lieber Development and assessment of human adenovirus type 11 as a gene transfer vector J. Virol. 79 8 2005 5090 5104
94. M. Suomalainen, M.Y. Nakano, S. Keller, K. Boucke, R.P. Stidwill, and U.F. Greber Microtubule-dependent plus- and minus end-directed motilities are competing processes for nuclear targeting of adenovirus J. Cell Biol. 144 4 1999 657 672
95. M. Suomalainen, M.Y. Nakano, K. Boucke, S. Keller, and U.F. Greber Adenovirus-activated PKA and p38/MAPK pathways boost microtubule-mediated nuclear targeting of virus EMBO J. 20 6 2001 1310 1319
96. B. Tauber, and T. Dobner Molecular regulation and biological function of adenovirus early genes: the E4 ORFs Gene 278 1-2 2001 1 23
97. O. Tokunaga, T. Yaegashi, J. Lowe, L. Dobbs, and R. Padmanabhan Sequence analysis in the E1 region of adenovirus type 4 DNA Virology 155 2 1986 418 433
98. A. Tolun, P. Alestrom, and U. Pettersson Sequence of inverted terminal repetitions from different adenoviruses: demonstration of conserved sequences and homology between SA7 termini and SV40 DNA Cell 17 3 1979 705 713
99. L. Tong Viral proteases Chem. Rev. 102 12 2002 4609 4626
100. W. van der Houven van Oordt, M.T. Diaz-Meco, J. Lozano, A.R. Krainer, J. Moscat, and J.F. Caceres The MKK(3/6)-p38-signaling cascade alters the subcellular distribution of hnRNP A1 and modulates alternative splicing regulation J. Cell Biol. 149 2 2000 307 316
101. R. Vogels, D. Zuijdgeest, R. van Rijnsoever, E. Hartkoorn, I. Damen, M.P. de Bethune, S. Kostense, G. Penders, N. Helmus, W. Koudstaal, M. Cecchini, A. Wetterwald, M. Sprangers, A. Lemckert, O. Ophorst, B. Koel, M. van Meerendonk, P. Quax, L. Panitti, J. Grimbergen, A. Bout, J. Goudsmit, and M. Havenga Replication-deficient human adenovirus type 35 vectors for gene transfer and vaccination: efficient human cell infection and bypass of preexisting adenovirus immunity J. Virol. 77 1 2003 8263 8271
102. D.J. Von Seggern, S. Huang, S.K. Fleck, S.C. Stevenson, and G.R. Nemerow Adenovirus vector pseudotyping in fiber-expressing cell lines: improved transduction of Epstein-Barr virus-transformed B cells J. Virol. 74 1 2000 354 362
103. G. Wadell Adenoviruses A.J. Zuckerman J.E. Banatvala J.R. Pattison Principles and Practice of Clinical Virology 4th ed. 2000 John Wiley and Sons 307 327
104. T.J. Wickham, P. Mathias, D.A. Cheresh, and G.R. Nemerow Integrins alpha v beta 3 and alpha v beta 5 promote adenovirus internalization but not virus attachment Cell 73 2 1993 309 319
105. C.M. Wiethoff, H. Wodrich, L. Gerace, and G.R. Nemerow Adenovirus protein VI mediates membrane disruption following capsid disassembly J. Virol. 79 4 2005 1992 2000
106. J. Wilson-Rawls, S.K. Saha, P. Krajcsi, A.E. Tollefson, L.R. Gooding, and W.S. Wold A 6700 MW membrane protein is encoded by region E3 of adenovirus type 2 Virology 178 1 1990 204 212
107. H. Wodrich, T. Guan, G. Cingolani, D. Von Seggern, G. Nemerow, and L. Gerace Switch from capsid protein import to adenovirus assembly by cleavage of nuclear transport signals EMBO J. 22 23 2003 6245 6255
108. W.S. Wold, and L.R. Gooding Region E3 of adenovirus: a cassette of genes involved in host immunosurveillance and virus-cell interactions Virology 184 1 1991 1 8
109. P. Yotnda, H. Onishi, H.E. Heslop, D. Shayakhmetov, A. Lieber, M. Brenner, and A. Davis Efficient infection of primitive hematopoietic stem cells by modified adenovirus Gene Ther. 8 12 2001 930 937
110. C.S. Young The structure and function of the adenovirus major late promoter Curr. Top. Microbiol. Immunol. 272 2003 213 249
111. Y. Zhang, J.P. Muyrers, G. Testa, and A.F. Stewart DNA cloning by homologous recombination in Escherichia coli Nat. Biotechnol. 18 12 2000 1314 1317
112. W. Zhang, J.A. Low, J.B. Christensen, and M.J. Imperiale Role for the adenovirus IVa2 protein in packaging of viral DNA J. Virol. 75 21 2001 10446 10454