SIMPLE interacts with NEDD4 and TSG101: Evidence for a role in lysosomal sorting and implications for Charcot-Marie-Tooth disease

Journal of Neuroscience Research

Volumn 82, Issue 1, 2005, Pages 43-50

  Shirk, Andrew J ^a   Anderson, Susan K ^a   Hashemi, Sayed H ^a   Chance, Phillip F ^a,b   Bennett, Craig L ^a,b  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

Author keywords

CMT1C; Golgi; Peripheral neuropathy; Protein degradation

Indexed keywords

MEMBRANE PROTEIN; SMALL INTEGRAL MEMBRANE PROTEIN OF THE LYSOSOME LATE ENDOSOME GENE; TUMOR SUSCEPTIBILITY GENE 101 PROTEIN; UBIQUITIN PROTEIN LIGASE NEDD4; UNCLASSIFIED DRUG;

ARTICLE; CELL MEMBRANE; CELL SELECTION; CELL VACUOLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; EMBRYO; GENE MUTATION; HEREDITARY MOTOR SENSORY NEUROPATHY; HUMAN; HUMAN CELL; LYSOSOME; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION;

B-LYMPHOCYTES; BLOTTING, WESTERN; CELL LINE, TRANSFORMED; CELL MEMBRANE; CHARCOT-MARIE-TOOTH DISEASE; CLONING, MOLECULAR; DNA-BINDING PROTEINS; ENDOSOMES; FLUORESCENT ANTIBODY TECHNIQUE; GOLGI APPARATUS; HUMANS; IMMUNOPRECIPITATION; LYSOSOMAL-ASSOCIATED MEMBRANE PROTEIN 1; LYSOSOMES; MODELS, BIOLOGICAL; MUTATION; NUCLEAR PROTEINS; PROTEIN BINDING; TRANSCRIPTION FACTORS; TRANSFECTION; UBIQUITIN-PROTEIN LIGASES;

EID: 27744474225     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/jnr.20628     Document Type: Article

References (28)

1. Babst M, Katzmann DJ, Estepa-Sabal EJ, Meerloo T, Emr SD. 2002. Escrt-III: an endosome-associated heterooligomeric protein complex required for mvb sorting. Dev Cell 3:271-282.
2. Bennett CL, Shirk AJ, Huynh HM, Street VA, Nelis E, Van Maldergem L, De Jonghe P, Jordanova A, Guergueltcheva V, Tournev I, Van Den Bergh P, Seeman P, Mazanec R, Prochazka T, Kremensky I, Haberlova J, Weiss MD, Timmerman V, Bird TD, Chance PF. 2004. SIMPLE mutation in demyelinating neuropathy and distribution in sciatic nerve. Ann Neurol 55:713-720.
3. Bonifacino JS, Traub LM. 2003. Signals for sorting of transmembrane proteins to endosomes and lysosomes. Annu Rev Biochem 72:395-447.
4. Chance PF, Matsunami N, Lensch W, Smith B, Bird TD. 1992. Analysis of the DNA duplication 17p11.2 in Charcot-Marie-Tooth neuropathy type 1 pedigrees: additional evidence for a third autosomal CMT1 locus. Neurology 42:2037-2041.
5. Dupre S, Volland C, Haguenauer-Tsapis R. 2001. Membrane transport: ubiquitylation in endosomal sorting. Curr Biol 11:932-934.
6. Griffith KJ, Chan EK, Lung CC, Hamel JC, Guo X, Miyachi K, Fritzler MJ. 1997. Molecular cloning of a novel 97-kd Golgi complex autoantigen associated with Sjogren's syndrome. Arthritis Rheum 40:1693-1702.
7. Horak J. 2003. The role of ubiquitin in down-regulation and intracellular sorting of membrane proteins: insights from yeast. Biochim Biophys Acta 1614:139-155.
8. Ingham RJ, Gish G, Pawson T. 2004. The Nedd4 family of E3 ubiquitin ligases: functional diversity within a common modular architecture. Oncogene 23:1972-1984.
9. Jolliffe CN, Harvey KF, Haines BP, Parasivam G, Kumar S. 2000. Identification of multiple proteins expressed in murine embryos as binding partners for the WW domains of the ubiquitin-protein ligase Nedd4. Biochem J 351:557-565.
10. Katzmann DJ, Stefan CJ, Babst M, Emr SD, Estepa-Sabal EJ, Meerloo T. 2003. Vps27 recruits ESCRT machinery to endosomes during MVB sorting Escrt-III: an endosome-associated heterooligomeric protein complex required for mvb sorting. J Cell Biol 162:413-423.
11. Liu N, Yamauchi J, Shooter EM. 2004. Recessive, but not dominant, mutations in peripheral myelin protein 22 gene show unique patterns of aggregation and intracellular trafficking. Neurobiol Dis 17:300-309.
12. Lu Q, Hope LW, Brasch M, Reinhard C, Cohen SN. 2003. TSG101 interaction with HRS mediates endosomal trafficking and receptor down-regulation. Proc Natl Acad Sci USA 100:7626-7631.
13. Ludes-Meyers JH, Kil H, Bednarek AK, Drake J, Bedford MT, Aldaz CM. 2004. WWOX binds the specific proline-rich ligand PPXY: identification of candidate interacting proteins. Oncogene 23:5049-5055.
14. Melcher K. 2004. New chemical crosslinking methods for the identification of transient protein-protein interactions with multiprotein complexes. Curr Protein Pept Sci 5:287-296.
15. Moriwaki Y, Begum NA, Kobayashi M, Matsumoto M, Toyoshima K, Seya T. 2001. Mycobacterium bovis Bacillus Calmette-Guerin and its cell wall complex induce a novel lysosomal membrane protein, SIMPLE, that bridges the missing link between lipopolysaccharide and p53-inducible gene, LITAF(PIG7), and estrogen-inducible gene, EET-1. J Biol Chem 276:23065-23076.
16. Notterpek L, Ryan MC, Tobler AR, Shooter EM. 1999. PMP22 accumulation in aggresomes: implications for CMT1A pathology. Neurobiol Dis 6:450-460.
17. Notterpek L, Shooter EM, Snipes GJ. 1997. Upregulation of the endosomal-lysosomal pathway in the trembler-J neuropathy. J Neurosci 17:4190-4200.
18. Pareek S, Notterpek L, Snipes GJ, Naef R, Sossin W, Laliberte J, Iacampo S, Suter U, Shooter EM, Murphy RA. 1997. Neurons promote the translocation of peripheral myelin protein 22 into myelin. J Neurosci 17:7754-7762.
19. Plant PJ, Yeger H, Staub O, Howard P, Rotin D. 1997. The C2 domain of the ubiquitin protein ligase Nedd4 mediates Ca2+-dependent plasma membrane localization. J Biol Chem 272:32329-32336.
20. Rotin D, Staub O, Haguenauer-Tsapis R. 2000. Ubiquitination and endocytosis of plasma membrane proteins: role of Nedd4/Rsp5p family of ubiquitin-protein ligases. J Membr Biol 176:1-17.
21. Ryan MC, Shooter EM, Notterpek L. 2002. Aggresome formation in neuropathy models based on peripheral myelin protein 22 mutations. Neurobiol Dis 10:109-118.
22. Shy M, Dyck P, Chance P, Lupski J, Klein C. 2005. Hereditary motor and sensory neuropathies: principles and classifications. In: Dyck P, Thomas P, editors. Peripheral neuropathy (4th ed.). Chap. 69; p. 1623-1659. Philadelphia: W.B. Saunders.
23. Street VA, Bennett CL, Goldy JD, Shirk AJ, Kleopa KA, Tempel BL, Lipe HP, Scherer SS, Bird TD, Chance PF. 2003. Mutation of a putative protein degradation gene LITAF/SIMPLE in Charcot-Marie-Tooth disease 1C. Neurology 60:22-26.
24. Street VA, Goldy JD, Golden AS, Tempel BL, Bird TD, Chance PF. 2002. Mapping of Charcot-Marie-Tooth disease type 1C to chromosome 16p identifies a novel locus for demyelinating neuropathies. Am J Hum Genet 70:244-250.
25. Timmins J, Schoehn G, Ricard-Blum S, Scianimanico S, Vernet T, Ruigrok RW, Weissenhorn W. 2003. Ebola virus matrix protein VP40 interaction with human cellular factors Tsg101 and Nedd4. J Mol Biol 326:493-502.
26. Vasilescu J, Guo X, Kast J. 2004. Identification of protein-protein interactions using in vivo cross-linking and mass spectrometry. Proteomics 4:3845-3854.
27. Wang G, McCaffery JM, Wendland B, Dupre S, Haguenauer-Tsapis R, Huibregtse JM. 2001. Localization of the Rsp5p ubiquitin-protein ligase at multiple sites within the endocytic pathway. Mol Cell Biol 21:3564-3575.
28. Xie W, Li L, Cohen SN. 1998. Cell cycle-dependent subcellular localization of the TSG101 protein and mitotic and nuclear abnormalities associated with TSG101 deficiency. Proc Natl Acad Sci USA 95:1595-1600.