Dual role of TRBP in HIV replication and RNA interference: Viral diversion of a cellular pathway or evasion from antiviral immunity?

Retrovirology

Volumn 2, Issue , 2005, Pages

  Gatignol, Anne ^a   Laine, Sebastien ^a   Clerzius, Guerline ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; INTERFERON; MICRORNA; PROTEIN KINASE R; RNA BINDING PROTEIN; SMALL INTERFERING RNA; TAR RNA BINDING PROTEIN; UNCLASSIFIED DRUG; VIRUS PROTEIN; VIRUS RNA; RIBONUCLEASE III; TRANS ACTIVATION RESPONSIVE RNA BINDING PROTEIN; TRANS-ACTIVATION RESPONSIVE RNA-BINDING PROTEIN;

ASTROCYTE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; IMMUNE RESPONSE; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; NOTE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN ISOLATION; RNA INTERFERENCE; RNA TRANSLATION; VIRUS EXPRESSION; VIRUS IMMUNITY; VIRUS INHIBITION; VIRUS REPLICATION; ARTICLE; HUMAN IMMUNODEFICIENCY VIRUS; IMMUNOLOGY; INNATE IMMUNITY; METABOLISM; PHYSIOLOGY;

ADENOVIRIDAE; HEXAPODA; HUMAN IMMUNODEFICIENCY VIRUS 1; MAMMALIA; PRIMATES; VACCINIA;

HIV; HUMANS; IMMUNITY, INNATE; RIBONUCLEASE III; RNA INTERFERENCE; RNA-BINDING PROTEINS; VIRUS REPLICATION;

EID: 27744458277     PISSN: 17424690     EISSN: 17424690     Source Type: Journal    
DOI: 10.1186/1742-4690-2-65     Document Type: Note

References (29)

1. Ding SW, Li H, Lu R, Li F, Li WX: RNA silencing: a conserved antiviral immunity of plants and animals. Virus Res 2004, 102:109-115.
2. Karpala AJ, Doran TJ, Bean AG: Immune responses to dsRNA: implications for gene silencing technologies. Immunol Cell Biol 2005, 83:211-216.
3. Lecellier CH, Voinnet O: RNA silencing: no mercy for viruses? Immunol Rev 2004, 198:285-303.
4. Lu R, Maduro M, Li F, Li HW, Broitman-Maduro G, Li WX, Ding SW: Animal virus replication and RNAi-mediated antiviral silencing in Caenorhabditis elegans. Nature 2005, 436:1040-1043.
5. Mak J: RNA interference: more than a research tool in the vertebrates' adaptive immunity. Retrovirology 2005, 2:35.
6. Wilkins C, Dishongh R, Moore SC, Whitt MA, Chow M, Machaca K: RNA interference is an antiviral defence mechanism in Caenorhabditis elegans. Nature 2005, 436:1044-1047.
7. Colbère-Garapin F, Blondel B, Saulnier A, Pelletier I, Labadie K: Silencing viruses by RNA interference. Microbes Infect 2005, 7:767-775.
8. Haasnoot J, Cupac D, Berkhout B: Inhibition of virus replication by RNA interference. J Biomed Sci 2003, 10:607-616.
9. Pfeffer S, Zavolan M, Grasser FA, Chien M, Russo JJ, Ju J, John B, Enright AJ, Marks D, Sander C, Tuschl T: Identification of virus-encoded microRNAs. Science 2004, 304:734-736.
10. Bennasser Y, Le SY, Benkirane M, Jeang KT: Evidence that HIV-1 encodes an siRNA and a suppressor of RNA silencing. Immunity 2005, 22:607-619.
11. Lecellier CH, Dunoyer P, Arar K, Lehmann-Che J, Eyquem S, Himber C, Saib A, Voinnet O: A cellular microRNA mediates antiviral defense in human cells. Science 2005, 308:557-560.
12. Li WX, Li H, Lu R, Li F, Dus M, Atkinson P, Brydon EW, Johnson KL, Garcia-Sastre A, Ball LA, Palese P, Ding SW: Interferon antagonist proteins of influenza and vaccinia viruses are suppressors of RNA silencing. Proc Natl Acad Sci USA 2004, 101:1350-1355.
13. Andersson MG, Haasnoot PC, Xu N, Berenjian S, Berkhout B, Akusjarvi G: Suppression of RNA interference by adenovirus virus-associated RNA. J Virol 2005, 79:9556-9565.
14. Mouland AJ, Heveker N, Gatignol A: Virus-cell interactions. In: Encyclopedia of Molecular Cell Biology and Molecular Medicine. Volume 15. 2nd edition. Edited by Meyers RA. Wiley-VCH Verlag, Germany; 2005, pp. 423-484.
15. Chendrimada TP, Gregory RI, Kumaraswamy E, Norman J, Cooch N, Nishikura K, Shiekhattar R: TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing. Nature 2005, 436:740-744.
16. Haase AD, Jaskiewicz L, Zhang H, Lainé S, Sack R, Gatignol A, Filipowicz W: TRBP, a regulator of cellular PKR and HIV-1 virus expression, interacts with Dicer and functions in RNA silencing. EMBO Rep 2005, 6:961-967.
17. Ong CL, Thorpe JC, Gorry PR, Bannwarth S, Jaworowski A, Howard JL, Chung S, Campbell S, Christensen HS, Clerzius G, Mouland AJ, Gatignol A, Purcell DF: Low TRBP levels support an innate Human Immunodeficiency Virus type 1 resistance in astrocytes by enhancing the PKR antiviral response. J Virol 2005, 79:12763-12772.
18. Gatignol A, Buckler-White A, Berkhout B, Jeang K-T: Characterization of a human TAR RNA-binding protein that activates the HIV-1 LTR. Science 1991, 251:1597-1600.
19. Duarte M, Graham K, Daher A, Battisti P-L, Bannwarth S, Segeral E, Jeang K-T, Gatignol A: Characterization of TRBP1 and TRBP2: stable stem-loop structure at the 5′ end of TRBP2 mRNA resembles HIV-1 TAR and is not found in its processed pseudogene. J Biomed Sci 2000, 7:494-506.
20. Daviet L, Erard M, Dorin D, Duarte M, Vaquero C, Gatignol A: The analysis of a binding difference between the two dsRNA binding domains in TRBP reveals the modular function of a KR-helix motif. Eur J Biochem 2000, 267:2419-2431.
21. Gatignol A, Buckler C, Jeang K-T: Relatedness of an RNA binding motif in HIV-1 TAR RNA binding protein TRBP to human P1/dsI kinase and Drosophila Staufen. Mol Cell Biol 1993, 13:2193-2202.
22. Benkirane M, Neuveut C, Chun RF, Smith SM, Samuel CE, Gatignol A, Jeang K-T: Oncogenic potential of TAR RNA-binding protein TRBP and its regulatory interaction with Protein Kinase PKR. EMBO J 1997, 16:611-624.
23. Daher A, Longuet M, Dorin D, Bois F, Segeral E, Bannwarth S, Battisti P-L, Purcell D, Benarous R, Vaquero C, Meurs EF, Gatignol A: Two dimerization domains in the Trans-activation response RNA-binding Protein (TRBP) individually reverse the Protein Kinase R inhibition of HIV-1 Long Terminal Repeat expression. J Biol Chem 2001, 276:33899-33905.
24. Park H, Davies MV, Langland JO, Chang H-W, Nam YS, Tartaglia J, Paoletti E, Jacobs BL, Kaufman RJ, Venkatesan S: TAR RNA-binding protein is an inhibitor of the interferon-induced protein kinase PKR. Proc Natl Acad Sci USA 1994, 91:4713-4717.
25. Dorin D, Bonnet MC, Bannwarth S, Gatignol A, Meurs EF, Vaquero C: The TAR RNA-binding protein, TRBP, stimulates the expression of TAR-containing RNAs in vitro and in vivo independently of its ability to inhibit the dsRNA-dependent kinase PKR. J Biol Chem 2003, 278:4440-4448.
26. Bannwarth S, Talakoub L, Letourneur F, Duarte M, Purcell DF, Hiscott J, Gatignol A: Organization of the human tarbp2 gene reveals two promoters that are repressed in an astrocytic cell line. J Biol Chem 2001, 276:48803-48813.
27. Jopling CL, Yi M, Lancaster AM, Lemon SM, Sarnow P: Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNA. Science 2005, 309:1577-1581.
28. Sheldon M, Ratnasabapathy R, Hernandez N: Characterization of the inducer of short transcripts, a human immunodeficiency virus type 1 transcriptional element that activates the synthesis of short RNAs. Mol Cell Biol 1993, 13:1251-1263.
29. Gunnery S, Rice AP, Robertson HD, Mathews MB: Tat-responsive region RNA of human immunodeficiency virus 1 can prevent activation of the double-stranded-RNA-activated protein kinase. Proc Natl Acad Sci USA 1990, 87:8687-8691.