Exposure to a 50-Hz magnetic field induces a circadian rhythm in 6-hydroxymelatonin sulfate excretion in mice

Journal of Radiation Research

Volumn 46, Issue 3, 2005, Pages 313-318

  Kumlin, Timo ^a   Heikkinen, Päivi ^a   Laitinen, Jarmo T ^a   Juutilainen, Jukka ^a  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

BODY FLUIDS; HORMONES; MAGNETIC FIELDS; PHYSIOLOGY; SENSITIVITY ANALYSIS; SULFUR COMPOUNDS;

CIRCADIAN LIGHTS; CIRCADIAN RHYTHMS; DARK PERIODS; EFFECT OF MAGNETIC FIELD; EXPOSED TO; FIELD EXPOSURE; LIGHT FIELDS; MAGNETIC-FIELD; PINEAL GLAND;

MAMMALS;

ANIMALIA;

6 HYDROXYMELATONIN; 6-HYDROXYMELATONIN; DRUG DERIVATIVE; MELATONIN;

ANIMAL; ARTICLE; BAGG ALBINO MOUSE; BIOLOGICAL RHYTHM; CIRCADIAN RHYTHM; DBA MOUSE; DRUG EFFECT; ELECTRICITY; ELECTROMAGNETIC FIELD; ENVIRONMENTAL EXPOSURE; FEMALE; METABOLISM; MOUSE; PHYSIOLOGY; RADIATION DOSE; RADIATION EXPOSURE; RADIATION RESPONSE; URINE;

ANIMALS; BIOLOGICAL CLOCKS; CIRCADIAN RHYTHM; DOSE-RESPONSE RELATIONSHIP, RADIATION; ELECTRICITY; ELECTROMAGNETIC FIELDS; ENVIRONMENTAL EXPOSURE; FEMALE; MELATONIN; MICE; MICE, INBRED BALB C; MICE, INBRED DBA; RADIATION DOSAGE;

EID: 27744439659     PISSN: 04493060     EISSN: 13499157     Source Type: Journal    
DOI: 10.1269/jrr.46.313     Document Type: Article

References (45)

1. Ahlbom, A., Day, N., Feychting, M., Roman, E., Skinner, J., Dockerty, J., Linet, M., McBride, M., Michaelis, J., Olsen, JH., Tynes, T., Verkasalo, P. K. (2000) A pooled analysis of magnetic fields and childhood leukaemia. Br. J. Cancer 83: 692-698.
2. Angelillo, I. F. and Villari, P. (1999) Residential exposure to electromagnetic fields and childhood leukaemia: a meta-analysis. Bull. World Health. Organ. 77: 906-915.
3. Greenland, S., Sheppard, A. R., Kaune, W. T., Poole, C., Kelsh, M. A. (2000) A pooled analysis of magnetic fields, wire codes, and childhood leukaemia. Childhood leukaemia-EMF study group. Epidemiology 11: 624-634.
4. Juutilainen, J., Lang, S, Rytömaa, T. (2000a) Possible cocarcinogenic effects of ELF electromagnetic fields may require repeated long-term interaction with known carcinogenic factors. Bioelectromagnetics 21: 122-128.
5. McCann, J., Kavet, R., Rafferty, C. N. (2000) Assessing the potential carcinogenic activity of magnetic fields using animal models. Environ. Health Perspect. 108 suppl 1: 79-100.
6. Lambrozo, J., Touitou, Y., Dab, W. (1996) Exploring the EMF-melatonin connection: A review of the possible effects of 50/60 Hz electric and magnetic fields on melatonin secretion. Int. J. Occup. Environ. Health 2: 37-47.
7. Stevens, R. G. (1987) Electric power use and breast cancer: a hypothesis. Am. J. Epidemiol. 125: 556-561.
8. Arendt, J. (1985) Mammalian pineal rhythms. Pineal Res. Rev. 3: 161-214.
9. Arendt, J., Bojkowski, C., Franey, C., Wright, J., Marks, V. (1985) Immunoassay of 6-hydroxymelatonin sulphate in human plasma and urine. J. Clin. Endocrinol. Metab. 60: 1166-1173.
10. Stieglitz, A., Spiegelhalter, F., Klante, G., Heldmaier, G. (1995) Urinary 6-sulphatoxymelatonin excretion reflects pineal melatonin secretion in the Dungarian hamster (Phodus sungorus). J. Pineal Res. 18: 69-76.
11. Pohjanvirta, R., Laitinen, J. T., Vakkuri, O., Linden, J., Kokkola, T., Unkila, M., Tuomisto, J. (1996) Mechanisms by which 2,3,7,8-tetrachlorodibenzo- p-dioxin (TCDD) reduces circulating melatonin levels in the rat. Toxicology 107: 85-97.
12. Reiter, R. J., Tan, D. X., Allegra, M. (2002) Melatonin: Reducing molecular pathology and dysfunction due to free radicals and associated reactants. Neuro. Endocrinol. Lett. 23 Suppl, 1: 3-8.
13. Karbownik, M. (2002) Potential anticarcinogenic action of melatonin and other antioxidants mediated by antioxidative mechanisms. Neuro. Endocrinol. Lett. 23 Suppl. 1: 39-44.
14. Sánchez-Barceló, E. J., Cos, S., Fernandez, R., Mediavilla, M. D. (2003) Melatonin and mammary cancer: a short review. Endocr. Relat. Cancer 10: 153-159.
15. Kato, M., Honma, K., Shigemitsu, T., Shiga, Y. (1994) Circularly polarized 50-Hz magnetic fields exposure reduces pineal gland and blood melatonin concentration of Long-Evans rats. Neurosci. Lett. 166: 59-62.
16. Mevissen, M., Lerchl, A., Szamel, M., Löscher, W. (1996) Exposure of DMBA-treated female rats in a 50-Hz, 50 7mu;Tesla magnetic field: effects on mammary tumor growth, melatonin levels, and lymphocyte activation. Carcinogenesis 17: 903-910.
17. Selmaoui, B., Touitou, Y. (1995) Sinusoidal 50-Hz magnetic fields depress rat pineal NAT activity and serum melatonin. Role of duration and intensity of exposure. Life Sci. 57: 1351-1358.
18. Yellon, S. M. (1994) Acute 60 Hz magnetic field exposure effects on the melatonin rhythm in the pineal gland and circulation of the adult Djungarian hamster. J. Pineal Res. 16: 136-144.
19. Bakos, J., Nagy, N., Thuróczy, G., Szabo, L. D. (2002) One week of exposure to 50 Hz, vertical magnetic field does not reduce urinary 6-sulphatoxymelatonin excretion of male Wistar rats. Bioelectromagnetics 23: 245-248.
20. John, T. M., Liu, G. Y., Brown, G. M. (1998) 60 Hz magnetic field exposure and urinary 6-sulphatoxymelatonin levels in the rat. Bioelectromagnetics 19: 172-180.
21. de Bruyn, L., de Jager, L., Kuyl, J. M. (2001) The influence of long-term exposure of mice to randomly varied power frequency magnetic fields on their nocturnal melatonin secretion patterns. Environ. Res. Section A85: 115-121.
22. Heikkinen, P., Kumlin, T., Laitinen, J.T., Komulainen, H., Juutilainen, J. (1999) Chronic exposure to 50-Hz magnetic fields or 900-MHz electromagnetic fields does not alter nocturnal 6-hydroxymelatonin sulfate secretion in CBA/S mice. Electro- Magnetobiol. 18: 33-42.
23. Burch, J. B., Reif, J. S., Noonan, C. W., Yost, M. G. (2000) Melatonin metabolite levels in workers exposed to 60-Hz magnetic fields: work in substations and with 3-phase conductors. J. Occup. Environ. Med. 42: 136-142.
24. Crasson, M., Backers, V., Pequeux, C., Claustrat, B., Legros, J. J. (2001) Daytime 50 Hz magnetic field exposure and plasma melatonin and urinary 6-sulfatoxymelatonin concentration profiles in humans. J. Pineal Res. 31: 234-241.
25. Davis, S., Kaune, W. T., Mirick, D. K., Chen, C., Stevens, R. G. (2001) Residential magnetic fields, light-at-night, and nocturnal urinary 6-sulfatoxymelatonin concentration in women. Am. J. Epidemiol. 154: 591-600.
26. Graham, C., Sastre, A., Cook, M. R., Gerkovich, M. M. (2001) All-night exposure to EMF does not alter urinary melatonin, 6-OHMS or immune measures in older men and women. J. Pineal Res. 31: 109-113.
27. Juutilainen, J., Stevens, R.G., Anderson, L. E., Hansen, N. H., Kilpeläinen, M., Kumlin, T., Laitinen, J. T., Sobel, E., Wilson, B. W. (2000b) Nocturnal 6-hydroxymelatonin sulfate excretion in female workers exposed to magnetic fields. J. Pineal Res. 28: 97-104.
28. Kumlin, T., Kosma, V.-M., Alhonen, A., Jänne, J., Komulainen, H., Lang, S., Rytömaa, T., Servomaa, K., Juutilainen, J. (1998a) Effects of 50 Hz magnetic fields on UV-induced skin tumourigenesis in ODC-transgenic mice. Int. J. Radiat. Biol. 73: 113-121.
29. Kumlin, T., Alhonen, L., Jänne, J., Lang, S., Kosma, V.-M., Juutilainen, J. (1998b) Epidermal ornithine decarboxylase and polyamines in mice exposed to 50 Hz magnetic fields and UV radiation. Bioelectromagnetics 19: 388-391.
30. Kumlin, T., Heikkinen, P., Kosma, V.-M., Alhonen, L., Jänne, J., Juutilainen, J. (2002) p53-independent apoptosis in UV-irradiated mouse skin: possible inhibition by 50 Hz magnetic fields. Radiat. Environ. Biophys. 41: 155-158.
31. Aldous, M. E., Arendt, J. (1988) Radioimmunoassay for 6-sulphatoxymelatonin in urine using an iodinated tracer. Ann. Clin. Biochem. 25: 298-303.
32. Klante, G., Brinschwitz, T., Secci, K., Wollnik, F., Steinlechner, S. (1997) Creatinine is an appropriate reference for urinary sulphatoxymelatonin of laboratory animals and humans. J. Pineal Res. 23: 191-197.
33. Valtonen, M., Laitinen, J. T., Eriksson, L. (1993) Renal melatonin excretion in sheep is enhanced by water diuresis. J. Endocrinol. 138: 445-450.
34. Conti, A., Maestroni, G. J. M. (1996) HPLC validation of a circadian melatonin rhythm in the pineal gland of inbred mice. J. Pineal Res. 20: 138-140.
35. Vivien-Roels, B., Malan, A., Rettori, M. C., Delagrange, P., Jeanniot, J. P., Pevet, P. (1998) Daily variations in pineal melatonin concentrations in inbred and outbred mice. J. Biol. Rhythms 13: 403-409.
36. Hamase, K., Tomita, T., Kiyomitsu, A., Zaitsu, K. (2000) Determination of pineal melatonin by precolumn derivatization reversed-phase high-pergormance liquid chromatography and its application to the study of circadian rhythm in rats and mice. Anal. Biochem. 279: 106-110.
37. Roseboom, P. H., Namboodiri, M. A. A., Zimonjic, D. B., Popescu, N. C., Rodriguez, I. R., Gastel, J. A., Klein, D. C. (1998) Natural melatonin 'knockdown' in C57BL/6J mice: rare mechanism truncates serotonin N-acetyltransferase. Mol. Brain. Res. 63: 189-197.
38. Ebihara, S., Hudson, D. J., Marks, T., Menaker, M. (1987) Pineal indole metabolism in the mouse. Brain Res. 416: 136-140.
39. Goto, M., Oshima, I., Tomita, T., Ebihara, S. (1989) Melatonin content of the pineal gland in different mouse strains. J. Pineal Res. 7: 195-204.
40. Olcese, J., Reuss, S., Vollrath, L. (1985) Evidence for the involvement of the visual system in mediating magnetic field effects on pineal melatonin synthesis in the rat. Brain Res 333: 382-384.
41. Olcese, J., Reuss, S., Stehle, J., Steinlechner, S., Vollrath, L. (1988) Responses of the mammalian retina to experimental alteration of the ambient magnetic field. Brain Res. 448: 325-330.
42. Reuss, S., Olcese, J. (1986) Magnetic field effects on the rat pineal gland: Role of retinal activation by light. Neurosci Lett 64: 97-101.
43. Choi Y. M., Jeong, J. H., Kim, J. S., Lee, B. C., Je, H. D., Sohn, U. D. (2003) Extremely low frequency magnetic field exposure modulates the diurnal rhythm of the pain threshold in mice. Bioelectromagnetics 24: 206-210.
44. Thoss, F., Bartsch, B., Tellschaft, D., Thoss, M. (1999) Periodic inversion of the vertical component of the Earth's magnetic field influences fluctuations of visual sensitivity in humans. Bioelectromagnetics 20: 459-461.
45. Lerchl, A., Nonaka, K. O., Stokkan, K.-A., Reiter, R. J. (1990) Marked rapid alterations in nocturnal pineal serotonin metabolism in mice and rats exposed to weak intermittent magnetic fields. Biochem. Biophys. Res. Comm. 169: 102-108.