Synthesis of 3-aryl-5-decapentyl-1,2,4-oxadiazoles possessing antiinflammatory and antitumor properties

Farmaco

Volumn 60, Issue 11-12, 2005, Pages 955-960

  Bezerra, Natércia M Miranda ^a   De Oliveira, Shalom P ^a   Srivastava, Rajendra M ^a   Da Silva, Joel R ^a  

^a DEPARTAMENTO DE QUÍMICA FUNDAMENTAL   (Brazil)

Author keywords

1,2,4 Oxadiazoles; Antiinflammatory activity; Antitumor property; Arylamidoximes; Spectroscopy

Indexed keywords

5 DECAPENTYL 3 (2 TOLYL) 1,2,4 OXADIAZOLE; 5 DECAPENTYL 3 (3 TOLYL) 1,2,4 OXADIAZOLE; 5 DECAPENTYL 3 (4 BROMOPHENYL) 5 DECAPENTYL 1,2,4 OXADIAZOLE; 5 DECAPENTYL 3 (4 CHLOROPHENYL) 5 DECAPENTYL 1,2,4 OXADIAZOLE; 5 DECAPENTYL 3 (4 TOLYL) 1,2,4 OXADIAZOLE; 5 DECAPENTYL 3 PHENYL 1,2,4 OXADIAZOLE; ACETYLSALICYLIC ACID; IBUPROFEN; LAPACHOL; OXADIAZOLE DERIVATIVE; PALMITIC ACID; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; BODY WEIGHT; CHEMICAL PROCEDURES; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE REGIMEN; DRUG EFFICACY; DRUG SCREENING; DRUG SYNTHESIS; MOUSE; NONHUMAN;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTINEOPLASTIC AGENTS; CARRAGEENAN; DISEASE MODELS, ANIMAL; DRUG SCREENING ASSAYS, ANTITUMOR; EDEMA; LETHAL DOSE 50; MICE; OXADIAZOLES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 27744437821     PISSN: 0014827X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.farmac.2005.08.003     Document Type: Article

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