-
1
-
-
0042706375
-
HIV-1 resistance to the gp41-dependent fusion inhibitor C-34
-
M. Armand-Ugon, A. Gutierrez, B. Clotet, and J.A. Este HIV-1 resistance to the gp41-dependent fusion inhibitor C-34 Antiviral. Res. 59 2 2003 137 142
-
(2003)
Antiviral. Res.
, vol.59
, Issue.2
, pp. 137-142
-
-
Armand-Ugon, M.1
Gutierrez, A.2
Clotet, B.3
Este, J.A.4
-
2
-
-
12244286063
-
Reduced fitness of HIV-1 resistant to CXCR4 antagonists
-
M. Armand-Ugon, M.E. Quinones-Mateu, A. Gutierez, J. Barretina, J. Blanco, D. Schols, E. De Clercq, B. Clotet, and J.A. Este Reduced fitness of HIV-1 resistant to CXCR4 antagonists Antiviral Ther. 8 1 2003 1 8
-
(2003)
Antiviral Ther.
, vol.8
, Issue.1
, pp. 1-8
-
-
Armand-Ugon, M.1
Quinones-Mateu, M.E.2
Gutierez, A.3
Barretina, J.4
Blanco, J.5
Schols, D.6
De Clercq, E.7
Clotet, B.8
Este, J.A.9
-
3
-
-
0037692990
-
Anti-HIV-1 activity of enfuvirtide (T-20) by inhibition of bystander cell death
-
J. Barretina, J. Blanco, M. Armand-Ugon, A. Gutierrez, B. Clotet, and J.A. Este Anti-HIV-1 activity of enfuvirtide (T-20) by inhibition of bystander cell death Antiviral Ther. 8 2 2003 155 161
-
(2003)
Antiviral Ther.
, vol.8
, Issue.2
, pp. 155-161
-
-
Barretina, J.1
Blanco, J.2
Armand-Ugon, M.3
Gutierrez, A.4
Clotet, B.5
Este, J.A.6
-
4
-
-
4143148495
-
Immunological and virological study of enfuvirtide-treated HIV-positive patients
-
J. Barretina, J. Blanco, A. Bonjoch, A. Llano, B. Clotet, and J.A. Este Immunological and virological study of enfuvirtide-treated HIV-positive patients AIDS 18 12 2004 1673 1682
-
(2004)
AIDS
, vol.18
, Issue.12
, pp. 1673-1682
-
-
Barretina, J.1
Blanco, J.2
Bonjoch, A.3
Llano, A.4
Clotet, B.5
Este, J.A.6
-
5
-
-
0026705746
-
The V3 region of the envelope glycoprotein of human immunodeficiency virus type 1 binds sulfated polysaccharides and CD4-derived synthetic peptides
-
D. Batinic, and F.A. Robey The V3 region of the envelope glycoprotein of human immunodeficiency virus type 1 binds sulfated polysaccharides and CD4-derived synthetic peptides J. Biol. Chem. 267 10 1992 6664 6671
-
(1992)
J. Biol. Chem.
, vol.267
, Issue.10
, pp. 6664-6671
-
-
Batinic, D.1
Robey, F.A.2
-
6
-
-
0042376485
-
A new classification for HIV-1
-
E.A. Berger, R.W. Doms, E.M. Fenyo, B.T. Korber, D.R. Littman, J.P. Moore, Q.J. Sattentau, H. Schuitemaker, J. Sodroski, and R.A. Weiss A new classification for HIV-1 Nature 391 6664 1998 240
-
(1998)
Nature
, vol.391
, Issue.6664
, pp. 240
-
-
Berger, E.A.1
Doms, R.W.2
Fenyo, E.M.3
Korber, B.T.4
Littman, D.R.5
Moore, J.P.6
Sattentau, Q.J.7
Schuitemaker, H.8
Sodroski, J.9
Weiss, R.A.10
-
7
-
-
0037455580
-
Cell-surface-expressed HIV-1 envelope induces the death of CD4 T cells during GP41-mediated hemifusion-like events
-
J. Blanco, J. Barretina, K.F. Ferri, E. Jacotot, A. Gutierrez, M. Armand-Ugon, C. Cabrera, G. Kroemer, B. Clotet, and J.A. Este Cell-surface-expressed HIV-1 envelope induces the death of CD4 T cells during GP41-mediated hemifusion-like events Virology 305 2 2003 318 329
-
(2003)
Virology
, vol.305
, Issue.2
, pp. 318-329
-
-
Blanco, J.1
Barretina, J.2
Ferri, K.F.3
Jacotot, E.4
Gutierrez, A.5
Armand-Ugon, M.6
Cabrera, C.7
Kroemer, G.8
Clotet, B.9
Este, J.A.10
-
8
-
-
4744354507
-
R5 HIV gp120-mediated cellular contacts induce the death of single CCR5-expressing CD4 T cells by a gp41-dependent mechanism
-
J. Blanco, J. Barretina, B. Clotet, and J.A. Este R5 HIV gp120-mediated cellular contacts induce the death of single CCR5-expressing CD4 T cells by a gp41-dependent mechanism J. Leukocyte Biol 76 4 2004 804 811
-
(2004)
J. Leukocyte Biol
, vol.76
, Issue.4
, pp. 804-811
-
-
Blanco, J.1
Barretina, J.2
Clotet, B.3
Este, J.A.4
-
9
-
-
3142540887
-
Effect of polyanion-resistance on HIV-1 infection
-
M.D. Bobardt, M. Armand-Ugon, I. Clotet, Z. Zhang, G. David, J.A. Este, and P.A. Gallay Effect of polyanion-resistance on HIV-1 infection Virology 325 2 2004 389 398
-
(2004)
Virology
, vol.325
, Issue.2
, pp. 389-398
-
-
Bobardt, M.D.1
Armand-Ugon, M.2
Clotet, I.3
Zhang, Z.4
David, G.5
Este, J.A.6
Gallay, P.A.7
-
10
-
-
0030970693
-
Core structure of gp41 from the HIV envelope glycoprotein
-
D.C. Chan, D. Fass, J.M. Berger, and P.S. Kim Core structure of gp41 from the HIV envelope glycoprotein Cell 89 2 1997 263 273
-
(1997)
Cell
, vol.89
, Issue.2
, pp. 263-273
-
-
Chan, D.C.1
Fass, D.2
Berger, J.M.3
Kim, P.S.4
-
11
-
-
14644411674
-
Ethanol potentiates HIV-1 gp120-induced apoptosis in human neurons via both the death receptor and NMDA receptor pathways
-
W. Chen, Z. Tang, P. Fortina, P. Patel, S. Addya, S. Surrey, E.A. Acheampong, M. Mukhtar, and R.J. Pomerantz Ethanol potentiates HIV-1 gp120-induced apoptosis in human neurons via both the death receptor and NMDA receptor pathways Virology 334 1 2005 59 73
-
(2005)
Virology
, vol.334
, Issue.1
, pp. 59-73
-
-
Chen, W.1
Tang, Z.2
Fortina, P.3
Patel, P.4
Addya, S.5
Surrey, S.6
Acheampong, E.A.7
Mukhtar, M.8
Pomerantz, R.J.9
-
12
-
-
0033607028
-
Structure-based identification of small molecule antiviral compounds targeted to the gp41 core structure of the human immunodeficiency virus type 1
-
A.K. Debnath, L. Radigan, and S. Jiang Structure-based identification of small molecule antiviral compounds targeted to the gp41 core structure of the human immunodeficiency virus type 1 J. Med. Chem. 42 17 1999 3203 3209
-
(1999)
J. Med. Chem.
, vol.42
, Issue.17
, pp. 3203-3209
-
-
Debnath, A.K.1
Radigan, L.2
Jiang, S.3
-
13
-
-
0031891516
-
AMD3100, a small molecule inhibitor of HIV-1 entry via the CXCR4 co-receptor
-
G.A. Donzella, D. Schols, S.W. Lin, J.A. Esté, K.A. Nagashima, P.J. Maddon, G.P. Allaway, T.P. Sakmar, G. Henson, E. De Clercq, and J.P. Moore AMD3100, a small molecule inhibitor of HIV-1 entry via the CXCR4 co-receptor Nat. Med. 4 1 1998 72 77
-
(1998)
Nat. Med.
, vol.4
, Issue.1
, pp. 72-77
-
-
Donzella, G.A.1
Schols, D.2
Lin, S.W.3
Esté, J.A.4
Nagashima, K.A.5
Maddon, P.J.6
Allaway, G.P.7
Sakmar, T.P.8
Henson, G.9
De Clercq, E.10
Moore, J.P.11
-
14
-
-
0042924181
-
Virus entry as a target for anti-HIV intervention
-
J.A. Este Virus entry as a target for anti-HIV intervention Curr. Med. Chem. 10 17 2003 1617 1632
-
(2003)
Curr. Med. Chem.
, vol.10
, Issue.17
, pp. 1617-1632
-
-
Este, J.A.1
-
15
-
-
0030754130
-
Development of resistance of human immunodeficiency virus type 1 to dextran sulfate associated with the emergence of specific mutations in the envelope gp120 glycoprotein
-
J.A. Este, D. Schols, K. De Vreese, K. Van Laethem, A.M. Vandamme, J. Desmyter, and E. De Clercq Development of resistance of human immunodeficiency virus type 1 to dextran sulfate associated with the emergence of specific mutations in the envelope gp120 glycoprotein Mol. Pharmacol. 52 1 1997 98 104
-
(1997)
Mol. Pharmacol.
, vol.52
, Issue.1
, pp. 98-104
-
-
Este, J.A.1
Schols, D.2
De Vreese, K.3
Van Laethem, K.4
Vandamme, A.M.5
Desmyter, J.6
De Clercq, E.7
-
16
-
-
0031886388
-
Human immunodeficiency virus glycoprotein gp120 as the primary target for the antiviral action of AR177 (Zintevir)
-
J.A. Este, C. Cabrera, D. Schols, P. Cherepanov, A. Gutierrez, M. Witvrouw, C. Pannecouque, Z. Debyser, R.F. Rando, B. Clotet, J. Desmyter, and E. De Clercq Human immunodeficiency virus glycoprotein gp120 as the primary target for the antiviral action of AR177 (Zintevir) Mol. Pharmacol. 53 2 1998 340 345
-
(1998)
Mol. Pharmacol.
, vol.53
, Issue.2
, pp. 340-345
-
-
Este, J.A.1
Cabrera, C.2
Schols, D.3
Cherepanov, P.4
Gutierrez, A.5
Witvrouw, M.6
Pannecouque, C.7
Debyser, Z.8
Rando, R.F.9
Clotet, B.10
Desmyter, J.11
De Clercq, E.12
-
17
-
-
0033059948
-
Shift of clinical human immunodeficiency virus type 1 isolates from X4 to R5 and prevention of emergence of the syncytium-inducing phenotype by blockade of CXCR4
-
J.A. Este, C. Cabrera, J. Blanco, A. Gutierrez, G. Bridger, G. Henson, B. Clotet, D. Schols, and E. De Clercq Shift of clinical human immunodeficiency virus type 1 isolates from X4 to R5 and prevention of emergence of the syncytium-inducing phenotype by blockade of CXCR4 J. Virol. 73 7 1999 5577 5585
-
(1999)
J. Virol.
, vol.73
, Issue.7
, pp. 5577-5585
-
-
Este, J.A.1
Cabrera, C.2
Blanco, J.3
Gutierrez, A.4
Bridger, G.5
Henson, G.6
Clotet, B.7
Schols, D.8
De Clercq, E.9
-
18
-
-
0036896463
-
Env chimeric virus technology for evaluating human immunodeficiency virus susceptibility to entry inhibitors
-
V. Fikkert, P. Cherepanov, K. Van Laethem, A. Hantson, B. Van Remoortel, C. Pannecouque, E. De Clercq, Z. Debyser, A.M. Vandamme, and M. Witvrouw Env chimeric virus technology for evaluating human immunodeficiency virus susceptibility to entry inhibitors Antimicrob. Agents Chemother. 46 12 2002 3954 3962
-
(2002)
Antimicrob. Agents Chemother.
, vol.46
, Issue.12
, pp. 3954-3962
-
-
Fikkert, V.1
Cherepanov, P.2
Van Laethem, K.3
Hantson, A.4
Van Remoortel, B.5
Pannecouque, C.6
De Clercq, E.7
Debyser, Z.8
Vandamme, A.M.9
Witvrouw, M.10
-
19
-
-
0036196484
-
Variability in the human immunodeficiency virus type 1 gp120 Env protein linked to phenotype-associated changes in the V3 loop
-
N.G. Hoffman, F. Seillier-Moiseiwitsch, J. Ahn, J.M. Walker, and R. Swanstrom Variability in the human immunodeficiency virus type 1 gp120 Env protein linked to phenotype-associated changes in the V3 loop J. Virol. 76 8 2002 3852 3864
-
(2002)
J. Virol.
, vol.76
, Issue.8
, pp. 3852-3864
-
-
Hoffman, N.G.1
Seillier-Moiseiwitsch, F.2
Ahn, J.3
Walker, J.M.4
Swanstrom, R.5
-
20
-
-
0034595078
-
A salt bridge between an N-terminal coiled coil of gp41 and an antiviral agent targeted to the gp41 core is important for anti-HIV-1 activity
-
S. Jiang, and A.K. Debnath A salt bridge between an N-terminal coiled coil of gp41 and an antiviral agent targeted to the gp41 core is important for anti-HIV-1 activity Biochem. Biophys. Res. Commun. 270 1 2000 153 157
-
(2000)
Biochem. Biophys. Res. Commun.
, vol.270
, Issue.1
, pp. 153-157
-
-
Jiang, S.1
Debnath, A.K.2
-
21
-
-
7244253012
-
N-substituted pyrrole derivatives as novel human immunodeficiency virus Type 1 entry inhibitors that interfere with the gp41 six-helix bundle formation and block virus fusion
-
S. Jiang, H. Lu, S. Liu, Q. Zhao, Y. He, and A.K. Debnath N-substituted pyrrole derivatives as novel human immunodeficiency virus Type 1 entry inhibitors that interfere with the gp41 six-helix bundle formation and block virus fusion Antimicrob. Agents Chemother. 48 11 2004 4349 4359
-
(2004)
Antimicrob. Agents Chemother.
, vol.48
, Issue.11
, pp. 4349-4359
-
-
Jiang, S.1
Lu, H.2
Liu, S.3
Zhao, Q.4
He, Y.5
Debnath, A.K.6
-
22
-
-
0031729823
-
Potent suppression of HIV-1 replication in humans by T-20, a peptide inhibitor of gp41-mediated virus entry
-
J.M. Kilby, S. Hopkins, T.M. Venetta, B. DiMassimo, G.A. Cloud, J.Y. Lee, L. Alldredge, E. Hunter, D. Lambert, D. Bolognesi, T. Matthews, M.R. Johnson, M.A. Nowak, G.M. Shaw, and M.S. Saag Potent suppression of HIV-1 replication in humans by T-20, a peptide inhibitor of gp41-mediated virus entry Nat. Med. 4 11 1998 1302 1307
-
(1998)
Nat. Med.
, vol.4
, Issue.11
, pp. 1302-1307
-
-
Kilby, J.M.1
Hopkins, S.2
Venetta, T.M.3
Dimassimo, B.4
Cloud, G.A.5
Lee, J.Y.6
Alldredge, L.7
Hunter, E.8
Lambert, D.9
Bolognesi, D.10
Matthews, T.11
Johnson, M.R.12
Nowak, M.A.13
Shaw, G.M.14
Saag, M.S.15
-
23
-
-
0023217711
-
Functional regions of the envelope glycoprotein of human immunodeficiency virus type 1
-
M. Kowalski, J. Potz, L. Basiripour, T. Dorfman, W.C. Goh, E. Terwilliger, A. Dayton, C. Rosen, W. Haseltine, and J. Sodroski Functional regions of the envelope glycoprotein of human immunodeficiency virus type 1 Science 237 4820 1987 1351 1355
-
(1987)
Science
, vol.237
, Issue.4820
, pp. 1351-1355
-
-
Kowalski, M.1
Potz, J.2
Basiripour, L.3
Dorfman, T.4
Goh, W.C.5
Terwilliger, E.6
Dayton, A.7
Rosen, C.8
Haseltine, W.9
Sodroski, J.10
-
24
-
-
0041561415
-
Enfuvirtide, an HIV-1 fusion inhibitor, for drug-resistant HIV infection in North and South America
-
J.P. Lalezari, K. Henry, M. O'Hearn, J.S. Montaner, P.J. Piliero, B. Trottier, S. Walmsley, C. Cohen, D.R. Kuritzkes, J.J. Eron Jr., J. Chung, R. DeMasi, L. Donatacci, C. Drobnes, J. Delehanty, and M. Salgo Enfuvirtide, an HIV-1 fusion inhibitor, for drug-resistant HIV infection in North and South America N. Engl. J. Med. 13 2003 13
-
(2003)
N. Engl. J. Med.
, vol.13
, pp. 13
-
-
Lalezari, J.P.1
Henry, K.2
O'Hearn, M.3
Montaner, J.S.4
Piliero, P.J.5
Trottier, B.6
Walmsley, S.7
Cohen, C.8
Kuritzkes, D.R.9
Eron Jr., J.J.10
Chung, J.11
Demasi, R.12
Donatacci, L.13
Drobnes, C.14
Delehanty, J.15
Salgo, M.16
-
25
-
-
0037849954
-
Efficacy of enfuvirtide in patients infected with drug-resistant HIV-1 in Europe and Australia
-
A. Lazzarin, B. Clotet, D. Cooper, J. Reynes, K. Arasteh, M. Nelson, C. Katlama, H.J. Stellbrink, J.F. Delfraissy, J. Lange, L. Huson, R. DeMasi, C. Wat, J. Delehanty, C. Drobnes, and M. Salgo Efficacy of enfuvirtide in patients infected with drug-resistant HIV-1 in Europe and Australia N. Engl. J. Med. 348 22 2003 2186 2195
-
(2003)
N. Engl. J. Med.
, vol.348
, Issue.22
, pp. 2186-2195
-
-
Lazzarin, A.1
Clotet, B.2
Cooper, D.3
Reynes, J.4
Arasteh, K.5
Nelson, M.6
Katlama, C.7
Stellbrink, H.J.8
Delfraissy, J.F.9
Lange, J.10
Huson, L.11
Demasi, R.12
Wat, C.13
Delehanty, J.14
Drobnes, C.15
Salgo, M.16
-
26
-
-
2442446904
-
HIV-resistance to viral entry inhibitors
-
L. Menendez-Arias, and J.A. Este HIV-resistance to viral entry inhibitors Curr. Pharm. Des. 10 15 2004 1845 1860
-
(2004)
Curr. Pharm. Des.
, vol.10
, Issue.15
, pp. 1845-1860
-
-
Menendez-Arias, L.1
Este, J.A.2
-
27
-
-
0033920212
-
Selective interactions of polyanions with basic surfaces on human immunodeficiency virus type 1 gp120
-
M. Moulard, H. Lortat-Jacob, I. Mondor, G. Roca, R. Wyatt, J. Sodroski, L. Zhao, W. Olson, P.D. Kwong, and Q.J. Sattentau Selective interactions of polyanions with basic surfaces on human immunodeficiency virus type 1 gp120 J. Virol. 74 4 2000 1948 1960
-
(2000)
J. Virol.
, vol.74
, Issue.4
, pp. 1948-1960
-
-
Moulard, M.1
Lortat-Jacob, H.2
Mondor, I.3
Roca, G.4
Wyatt, R.5
Sodroski, J.6
Zhao, L.7
Olson, W.8
Kwong, P.D.9
Sattentau, Q.J.10
-
28
-
-
0034623005
-
T-Coffee: A novel method for fast and accurate multiple sequence alignment
-
C. Notredame, D.G. Higgins, and J. Heringa T-Coffee: a novel method for fast and accurate multiple sequence alignment J. Mol. Biol. 302 1 2000 205 217
-
(2000)
J. Mol. Biol.
, vol.302
, Issue.1
, pp. 205-217
-
-
Notredame, C.1
Higgins, D.G.2
Heringa, J.3
-
29
-
-
0028824505
-
T30177, an oligonucleotide stabilized by an intramolecular guanosine octet, is a potent inhibitor of laboratory strains and clinical isolates of human immunodeficiency virus type 1
-
J.O. Ojwang, R.W. Buckheit, Y. Pommier, A. Mazumder, K. De Vreese, J.A. Esté, D. Reymen, L.A. Pallansch, C. Lackman-Smith, T.L. Wallace, E. De Clercq, M.S. McGrath, and R. Rando T30177, an oligonucleotide stabilized by an intramolecular guanosine octet, is a potent inhibitor of laboratory strains and clinical isolates of human immunodeficiency virus type 1 Antimicrob. Agents Chemother. 39 11 1995 2426 2435
-
(1995)
Antimicrob. Agents Chemother.
, vol.39
, Issue.11
, pp. 2426-2435
-
-
Ojwang, J.O.1
Buckheit, R.W.2
Pommier, Y.3
Mazumder, A.4
De Vreese, K.5
Esté, J.A.6
Reymen, D.7
Pallansch, L.A.8
Lackman-Smith, C.9
Wallace, T.L.10
De Clercq, E.11
McGrath, M.S.12
Rando, R.13
-
30
-
-
0028824505
-
T30177, an oligonucleotide stabilized by an intramolecular guanosine octet, is a potent inhibitor of laboratory strains and clinical isolates of human immunodeficiency virus type 1
-
J.O. Ojwang, R.W. Buckheit, Y. Pommier, A. Mazumder, K. De Vreese, J.A. Este, D. Reymen, L.A. Pallansch, C. Lackman-Smith, and T.L. Wallace T30177, an oligonucleotide stabilized by an intramolecular guanosine octet, is a potent inhibitor of laboratory strains and clinical isolates of human immunodeficiency virus type 1 Antimicrob. Agents Chemother. 39 11 1995 2426 2435
-
(1995)
Antimicrob. Agents Chemother.
, vol.39
, Issue.11
, pp. 2426-2435
-
-
Ojwang, J.O.1
Buckheit, R.W.2
Pommier, Y.3
Mazumder, A.4
De Vreese, K.5
Este, J.A.6
Reymen, D.7
Pallansch, L.A.8
Lackman-Smith, C.9
Wallace, T.L.10
-
31
-
-
0035918220
-
N-linked glycosylation of the HIV type-1 gp120 envelope glycoprotein as a major determinant of CCR5 and CXCR4 coreceptor utilization
-
G. Pollakis, S. Kang, A. Kliphuis, M.I. Chalaby, J. Goudsmit, and W.A. Paxton N-linked glycosylation of the HIV type-1 gp120 envelope glycoprotein as a major determinant of CCR5 and CXCR4 coreceptor utilization J. Biol. Chem. 276 16 2001 13433 13441
-
(2001)
J. Biol. Chem.
, vol.276
, Issue.16
, pp. 13433-13441
-
-
Pollakis, G.1
Kang, S.2
Kliphuis, A.3
Chalaby, M.I.4
Goudsmit, J.5
Paxton, W.A.6
-
32
-
-
20444404968
-
Heparan sulfate targets the HIV-1 envelope glycoprotein gp120 coreceptor binding site
-
R.R. Vives, A. Imberty, Q.J. Sattentau, and H. Lortat-Jacob Heparan sulfate targets the HIV-1 envelope glycoprotein gp120 coreceptor binding site J. Biol. Chem. 280 22 2005 21353 21357
-
(2005)
J. Biol. Chem.
, vol.280
, Issue.22
, pp. 21353-21357
-
-
Vives, R.R.1
Imberty, A.2
Sattentau, Q.J.3
Lortat-Jacob, H.4
-
33
-
-
0032546844
-
The HIV-1 envelope glycoproteins: Fusogens, antigens, and immunogens
-
R. Wyatt, and J. Sodroski The HIV-1 envelope glycoproteins: fusogens, antigens, and immunogens Science 280 5371 1998 1884 1888
-
(1998)
Science
, vol.280
, Issue.5371
, pp. 1884-1888
-
-
Wyatt, R.1
Sodroski, J.2
|