A phase I/II study of oxaliplatin when added to 5-fluorouracil and leucovorin and pelvic radiation in locally advanced rectal cancer: A Colorectal Clinical Oncology Group (CCOG) study

British Journal of Cancer

Volumn 93, Issue 9, 2005, Pages 993-998

  Sebag Montefiore, D ^a   Glynne Jones, R ^b   Falk, S ^c   Meadows, H M ^d   Maughan, T ^e  

^a Northern and Yorkshire Clinical Trials and Research Unit   (United Kingdom)

^b MOUNT VERNON HOSPITAL   (United Kingdom)

^c BRISTOL HAEMATOLOGY AND ONCOLOGY CENTRE   (United Kingdom)

^d IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^e VELINDRE CANCER CENTRE   (United Kingdom)

Author keywords

5 Fluorouracil; Locally advanced rectal cancer; Oxaliplatin; Preoperative chemoradiation

Indexed keywords

FLUOROURACIL; FOLINIC ACID; OXALIPLATIN;

ADULT; ADVANCED CANCER; AGED; ANEMIA; ARTICLE; BLOOD TOXICITY; CANCER COMBINATION CHEMOTHERAPY; CANCER RADIOTHERAPY; CANCER RECURRENCE; CANCER SURGERY; CANCER SURVIVAL; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIARRHEA; DOSE CALCULATION; DRUG DOSE REDUCTION; DRUG DOSE REGIMEN; FEMALE; HISTOPATHOLOGY; HUMAN; LOW DRUG DOSE; MALE; MAXIMUM TOLERATED DOSE; METASTASIS; NAUSEA; NEUROPATHY; NEUROTOXICITY; NEUTROPENIA; PHASE 1 CLINICAL TRIAL; PHASE 2 CLINICAL TRIAL; PREOPERATIVE TREATMENT; PRIORITY JOURNAL; RECTUM CANCER; SENSORIMOTOR NEUROPATHY; THROMBOCYTOPENIA; TREATMENT OUTCOME; VOMITING;

ADULT; AGED; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; COMBINED MODALITY THERAPY; DISEASE-FREE SURVIVAL; FEMALE; FLUOROURACIL; HUMANS; LEUCOVORIN; MALE; MAXIMUM TOLERATED DOSE; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; NEOPLASM STAGING; ORGANOPLATINUM COMPOUNDS; PELVIS; RADIOTHERAPY, HIGH-ENERGY; RECTAL NEOPLASMS; TREATMENT OUTCOME;

EID: 27644493797     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/sj.bjc.6602818     Document Type: Article

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