메뉴 건너뛰기




Volumn 50, Issue 2, 2001, Pages 427-434

Combined chemo- and radiotherapy vs. radiotherapy alone in the treatment of primary, nonresectable adenocarcinoma of the rectum

Author keywords

Chemoradiotherapy; Nonresectable; Radiotherapy; Randomized trial; Rectal cancer

Indexed keywords

CHEMOTHERAPY; PATIENT MONITORING; RADIOTHERAPY; SURGERY; TOXICITY; TUMORS;

EID: 17344384995     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0360-3016(01)01479-1     Document Type: Article
Times cited : (122)

References (43)
  • 1
    • 0021189218 scopus 로고
    • The effect of malignant and inflammatory fixation of rectal carcinoma on prognosis after rectal excision
    • Durdey P., Williams N.S. The effect of malignant and inflammatory fixation of rectal carcinoma on prognosis after rectal excision. Br J Surg. 71:1984;787-790.
    • (1984) Br J Surg , vol.71 , pp. 787-790
    • Durdey, P.1    Williams, N.S.2
  • 2
    • 0021957059 scopus 로고
    • Preoperative irradiation of primarily unresectable adenocarcinoma of the rectum and rectosigmoid
    • Påhlman L., Glimelius B., Ginman C., et al. Preoperative irradiation of primarily unresectable adenocarcinoma of the rectum and rectosigmoid. Acta Radiol Oncol. 24:1985;35-40.
    • (1985) Acta Radiol Oncol , vol.24 , pp. 35-40
    • Påhlman, L.1    Glimelius, B.2    Ginman, C.3
  • 3
    • 0033011156 scopus 로고    scopus 로고
    • Changed strategy in the treatment of rectal cancer improves survival: Results from a single unit series
    • Dahlberg M., Glimelius B., Pahlman L. Changed strategy in the treatment of rectal cancer improves survival Results from a single unit series . Br J Surg. 86:1999;379-384.
    • (1999) Br J Surg , vol.86 , pp. 379-384
    • Dahlberg, M.1    Glimelius, B.2    Pahlman, L.3
  • 4
    • 0018870959 scopus 로고
    • Irradiation and surgery for primarily inoperable rectal adenocarcinoma
    • Bjerkeset T., Dahl O. Irradiation and surgery for primarily inoperable rectal adenocarcinoma. Dis Colon Rectum. 23:1980;298-303.
    • (1980) Dis Colon Rectum , vol.23 , pp. 298-303
    • Bjerkeset, T.1    Dahl, O.2
  • 5
    • 0026077491 scopus 로고
    • Preoperative irradiation for cancer of the rectum with extrarectal fixation
    • Tobin R., Mohiuddin M., Marks G. Preoperative irradiation for cancer of the rectum with extrarectal fixation. Int J Radiat Oncol Biol Phys. 21:1991;1127-1132.
    • (1991) Int J Radiat Oncol Biol Phys , vol.21 , pp. 1127-1132
    • Tobin, R.1    Mohiuddin, M.2    Marks, G.3
  • 6
    • 0019992967 scopus 로고
    • Long-time survivors after preoperative pelvic radiation therapy for locally unresectable rectal and sigmoid carcinoma
    • Kopelson G. Long-time survivors after preoperative pelvic radiation therapy for locally unresectable rectal and sigmoid carcinoma. Dis Colon Rectum. 25:1982;644-647.
    • (1982) Dis Colon Rectum , vol.25 , pp. 644-647
    • Kopelson, G.1
  • 7
    • 0020513906 scopus 로고
    • Preoperative irradiation for unresectable rectal and rectosigmoid carcinomas
    • Dosoretz D.E., Gunderson L.L., Hedberg S., et al. Preoperative irradiation for unresectable rectal and rectosigmoid carcinomas. Cancer. 52:1989;814-818.
    • (1989) Cancer , vol.52 , pp. 814-818
    • Dosoretz, D.E.1    Gunderson, L.L.2    Hedberg, S.3
  • 8
    • 0021070566 scopus 로고
    • Dose-response relationship for radiation therapy of recurrent, residual, and primarily inoperable colorectal cancer
    • Overgaard M., Overgaard J., Sell A. Dose-response relationship for radiation therapy of recurrent, residual, and primarily inoperable colorectal cancer. Radiother Oncol. 1:1984;217-222.
    • (1984) Radiother Oncol , vol.1 , pp. 217-222
    • Overgaard, M.1    Overgaard, J.2    Sell, A.3
  • 9
    • 0021224286 scopus 로고
    • Radiotherapy and resection for apparently inoperable rectal carcinoma
    • Mella O., Dahl O., Horn A., et al. Radiotherapy and resection for apparently inoperable rectal carcinoma. Dis Colon Rectum. 27:1984;663-668.
    • (1984) Dis Colon Rectum , vol.27 , pp. 663-668
    • Mella, O.1    Dahl, O.2    Horn, A.3
  • 10
    • 0023871520 scopus 로고
    • The search for therapeutic gain in the combination of radiotherapy and chemotherapy
    • Steel G.G. The search for therapeutic gain in the combination of radiotherapy and chemotherapy. Radiother Oncol. 11:1988;31-53.
    • (1988) Radiother Oncol , vol.11 , pp. 31-53
    • Steel, G.G.1
  • 11
    • 0022970363 scopus 로고
    • Experimental studies on interactions of radiation and cancer chemotherapeutic drugs in normal tissues and a solid tumour
    • von der Maase H. Experimental studies on interactions of radiation and cancer chemotherapeutic drugs in normal tissues and a solid tumour. Radiother Oncol 1986;7:47-68.
    • (1986) Radiother Oncol , vol.7 , pp. 47-68
    • Von Der Maase, H.1
  • 12
    • 0020393438 scopus 로고
    • Pharmacologic requirements for obtaining sensitization of human tumor cells in vitro to combined 5-fluorouracil or ftorafur and x-rays
    • Byfield J., Calabro-Jones P., Klisak I., et al. Pharmacologic requirements for obtaining sensitization of human tumor cells in vitro to combined 5-fluorouracil or ftorafur and x-rays. Int J Radiat Oncol Biol Phys. 8:1982;1923-1933.
    • (1982) Int J Radiat Oncol Biol Phys , vol.8 , pp. 1923-1933
    • Byfield, J.1    Calabro-Jones, P.2    Klisak, I.3
  • 13
    • 0014691062 scopus 로고
    • Combined 5-fluorouracil and supervoltage radiation therapy of locally unresectable gastrointestinal cancer
    • Moertel C.G., Childs D.S. Jr, Reitemeier R.J., et al. Combined 5-fluorouracil and supervoltage radiation therapy of locally unresectable gastrointestinal cancer. Lancet. 2:1969;865-867.
    • (1969) Lancet , vol.2 , pp. 865-867
    • Moertel, C.G.1    Childs D.S., Jr.2    Reitemeier, R.J.3
  • 14
    • 0021970675 scopus 로고
    • Radiation therapy alone or in combination with chemotherapy in the treatment of residual or inoperable carcinoma of the rectum and rectosigmoid or pelvic recurrence following colorectal surgery
    • Radiation Therapy Oncology Group study (76-16)
    • Rominger CJ, Gelber RD, Gunderson LL; et al. Radiation therapy alone or in combination with chemotherapy in the treatment of residual or inoperable carcinoma of the rectum and rectosigmoid or pelvic recurrence following colorectal surgery. Radiation Therapy Oncology Group study (76-16). Am J Clin Oncol 1985;8:118-127.
    • (1985) Am J Clin Oncol , vol.8 , pp. 118-127
    • Rominger, C.J.1    Gelber, R.D.2    Gunderson, L.L.3
  • 15
    • 0027485342 scopus 로고
    • A randomized feasibility study evaluating the effect of radiotherapy alone or combined with 5-fluorouracil in the treatment of locally recurrent or inoperable colorectal carcinoma
    • Overgaard M., Bertelsen K., Dalmark M., et al. A randomized feasibility study evaluating the effect of radiotherapy alone or combined with 5-fluorouracil in the treatment of locally recurrent or inoperable colorectal carcinoma. Acta Oncol. 32:1993;547-553.
    • (1993) Acta Oncol , vol.32 , pp. 547-553
    • Overgaard, M.1    Bertelsen, K.2    Dalmark, M.3
  • 16
    • 0027180876 scopus 로고
    • The efficacy of preoperative 5-fluorouracil, high dose leucovorin and sequential radiation therapy for unresectable rectal cancer
    • Minsky B.D., Cohen A.M., Kemeny N., et al. The efficacy of preoperative 5-fluorouracil, high dose leucovorin and sequential radiation therapy for unresectable rectal cancer. Cancer. 71:1993;3486-3492.
    • (1993) Cancer , vol.71 , pp. 3486-3492
    • Minsky, B.D.1    Cohen, A.M.2    Kemeny, N.3
  • 17
    • 0029681983 scopus 로고    scopus 로고
    • Preoperative treatment of patients with locally advanced unresectable rectal adenocarcinoma utilizing continuous chronobiologically shaped 5-fluorouracil infusion and radiation therapy
    • Marsh R. de W., Chu N.M., Vauthey J.N., et al. Preoperative treatment of patients with locally advanced unresectable rectal adenocarcinoma utilizing continuous chronobiologically shaped 5-fluorouracil infusion and radiation therapy. Cancer. 78:1996;217-225.
    • (1996) Cancer , vol.78 , pp. 217-225
    • Marsh, R.D.W.1    Chu, N.M.2    Vauthey, J.N.3
  • 18
    • 0032850210 scopus 로고    scopus 로고
    • Phase II study of radiochemotherapy with UFT and low-dose oral leucovorin in patients with unresectable rectal cancer
    • De La Torre A., Ramos S., Valcárcel F., et al. Phase II study of radiochemotherapy with UFT and low-dose oral leucovorin in patients with unresectable rectal cancer. Int J Radiat Oncol Biol Phys. 45:1999;629-634.
    • (1999) Int J Radiat Oncol Biol Phys , vol.45 , pp. 629-634
    • De La Torre, A.1    Ramos, S.2    Valcárcel, F.3
  • 19
    • 0032170172 scopus 로고    scopus 로고
    • Preoperative radiation with concurrent 5-fluorouracil continuous infusion for locally advanced unresectable rectal cancer
    • Videtic G.M.M., Fisher B.J., Perera F.E., et al. Preoperative radiation with concurrent 5-fluorouracil continuous infusion for locally advanced unresectable rectal cancer. Int J Radiat Oncol Biol Phys. 42:1998;319-324.
    • (1998) Int J Radiat Oncol Biol Phys , vol.42 , pp. 319-324
    • Videtic, G.M.M.1    Fisher, B.J.2    Perera, F.E.3
  • 20
    • 0024331290 scopus 로고
    • Preoperative irradiation with and without chemotherapy (MFL) in the treatment of primary non-resectable adenocarcinoma of the rectum. Results from two consecutive studies
    • Frykholm G., Glimelius B., Påhlman L. Preoperative irradiation with and without chemotherapy (MFL) in the treatment of primary non-resectable adenocarcinoma of the rectum. Results from two consecutive studies. Eur J Cancer Clin Oncol. 25:1989;1535-1541.
    • (1989) Eur J Cancer Clin Oncol , vol.25 , pp. 1535-1541
    • Frykholm, G.1    Glimelius, B.2    Påhlman, L.3
  • 21
    • 85030353282 scopus 로고
    • ICRU report
    • International Commission on Radiation Units and Measurements. Bethesda, MD
    • ICRU report 50. Prescribing, recording and reporting photon beam therapy. International Commission on Radiation Units and Measurements. Bethesda, MD, 1993.
    • (1993) Prescribing, Recording and Reporting Photon Beam Therapy , vol.50
  • 24
    • 0026673233 scopus 로고
    • Non-resectable adenocarcinoma of the rectum assessed by MR imaging before and after chemotherapy and irradiation
    • Frykholm G., Nyman R., Glimelius B., et al. Non-resectable adenocarcinoma of the rectum assessed by MR imaging before and after chemotherapy and irradiation. Acta Radiol. 33:1992;447-452.
    • (1992) Acta Radiol , vol.33 , pp. 447-452
    • Frykholm, G.1    Nyman, R.2    Glimelius, B.3
  • 25
    • 0027520967 scopus 로고
    • Biochemical modulation of 5-fluorouracil: A randomized comparison of sequential methotrexate, 5-fluorouracil and leucovorin versus sequential 5-fluorouracil and leucovorin in patients with advanced symptomatic colorectal cancer
    • Biochemical modulation of 5-fluorouracil A randomized comparison of sequential methotrexate, 5-fluorouracil and leucovorin versus sequential 5-fluorouracil and leucovorin in patients with advanced symptomatic colorectal cancer . Ann Oncol. 4:1993;235-241.
    • (1993) Ann Oncol , vol.4 , pp. 235-241
  • 26
    • 0017365573 scopus 로고
    • Design and analysis of randomized clinical trials requiring prolonged observation of each patient. II. Analysis and examples
    • Peto R., Pike M., Armitage P., et al. Design and analysis of randomized clinical trials requiring prolonged observation of each patient. II. Analysis and examples. Br J Cancer. 35:1977;1-39.
    • (1977) Br J Cancer , vol.35 , pp. 1-39
    • Peto, R.1    Pike, M.2    Armitage, P.3
  • 27
    • 0021869546 scopus 로고
    • Combination chemoradiotherapy for residual, recurrent or inoperable carcinoma of the rectum: E.C.O.G study (EST 3276)
    • Danjoux C.E., Gelber R.D., Catton G.E., et al. Combination chemoradiotherapy for residual, recurrent or inoperable carcinoma of the rectum E.C.O.G study (EST 3276) . Int J Radiat Oncol Biol Phys. 11:1985;765-771.
    • (1985) Int J Radiat Oncol Biol Phys , vol.11 , pp. 765-771
    • Danjoux, C.E.1    Gelber, R.D.2    Catton, G.E.3
  • 28
    • 0025778030 scopus 로고
    • Preoperative high dose leucovorin/5-fluorouracil and radiation therapy for unresectable rectal cancer
    • Minsky B.D., Kemeny M., Cohen A.M., et al. Preoperative high dose leucovorin/5-fluorouracil and radiation therapy for unresectable rectal cancer. Cancer. 67:1991;2859-2866.
    • (1991) Cancer , vol.67 , pp. 2859-2866
    • Minsky, B.D.1    Kemeny, M.2    Cohen, A.M.3
  • 29
    • 0015044371 scopus 로고
    • Cumulative radiation effect. : Part I: Fractionated treatment regimes
    • Kirk J., Gray W.N., Watson E.R. Cumulative radiation effect. Part I: Fractionated treatment regimes . Clin Radiol. 22:1971;145-155.
    • (1971) Clin Radiol , vol.22 , pp. 145-155
    • Kirk, J.1    Gray, W.N.2    Watson, E.R.3
  • 30
    • 0021260046 scopus 로고
    • The influence of fraction size in radiotherapy on the late normal tissue reaction - I & II
    • Turesson I., Notter G. The influence of fraction size in radiotherapy on the late normal tissue reaction - I & II. Int J Radiat Oncol Biol Phys. 10:1984;593-606.
    • (1984) Int J Radiat Oncol Biol Phys , vol.10 , pp. 593-606
    • Turesson, I.1    Notter, G.2
  • 31
    • 0024358259 scopus 로고
    • The linear-quadratic formula and progress in fractionated radiotherapy
    • Fowler J.F. The linear-quadratic formula and progress in fractionated radiotherapy. Br J Radiol. 62:1989;679-694.
    • (1989) Br J Radiol , vol.62 , pp. 679-694
    • Fowler, J.F.1
  • 32
    • 0021792174 scopus 로고
    • Prolongation of the disease-free interval in surgically treated rectal carcinoma
    • Prolongation of the disease-free interval in surgically treated rectal carcinoma. New Engl J Med. 312:1985;1464-1472.
    • (1985) New Engl J Med , vol.312 , pp. 1464-1472
  • 33
    • 0026071185 scopus 로고
    • Effective surgical adjuvant therapy for high-risk rectal cancer
    • Krook J.E., Moertel C.G., Gunderson L.L., et al. Effective surgical adjuvant therapy for high-risk rectal cancer. New Engl J Med. 324:1991;709-715.
    • (1991) New Engl J Med , vol.324 , pp. 709-715
    • Krook, J.E.1    Moertel, C.G.2    Gunderson, L.L.3
  • 34
    • 0023836214 scopus 로고
    • Postoperative adjuvant chemotherapy or radiation therapy for rectal cancer: Results from NSABP Protocol R-01
    • Fisher B., Wolmark N., Rockette H., et al. Postoperative adjuvant chemotherapy or radiation therapy for rectal cancer Results from NSABP Protocol R-01 . J Natl Cancer Inst. 80:1988;21-29.
    • (1988) J Natl Cancer Inst , vol.80 , pp. 21-29
    • Fisher, B.1    Wolmark, N.2    Rockette, H.3
  • 35
    • 0030805013 scopus 로고    scopus 로고
    • Randomized controlled trial of postoperative radiotherapy and short-term time-scheduled 5-fluorouracil against surgery alone in the treatment of Dukes B and C rectal cancer
    • Tveit K.M., Guldvog I., Hagen S., et al. Randomized controlled trial of postoperative radiotherapy and short-term time-scheduled 5-fluorouracil against surgery alone in the treatment of Dukes B and C rectal cancer. Br J Surg. 84:1997;1130-1135.
    • (1997) Br J Surg , vol.84 , pp. 1130-1135
    • Tveit, K.M.1    Guldvog, I.2    Hagen, S.3
  • 36
    • 0028136295 scopus 로고
    • Improving adjuvant therapy for rectal cancer by combining protracted infusion fluorouracil with radiation therapy after curative surgery
    • O'Connell M.J., Martenson J.A., Wieand H.S., et al. Improving adjuvant therapy for rectal cancer by combining protracted infusion fluorouracil with radiation therapy after curative surgery. N Engl J Med. 331:1994;502-507.
    • (1994) N Engl J Med , vol.331 , pp. 502-507
    • O'Connell, M.J.1    Martenson, J.A.2    Wieand, H.S.3
  • 37
    • 0025710611 scopus 로고
    • NIH Consensus Conference. Adjuvant therapy for patients with colon and rectal cancer
    • NIH Consensus Conference. Adjuvant therapy for patients with colon and rectal cancer. JAMA 1990;264:1444-1450.
    • (1990) JAMA , vol.264 , pp. 1444-1450
  • 38
    • 0032986274 scopus 로고    scopus 로고
    • Indications for and results of combined modality treatment of colorectal cancer
    • Gunderson L.L. Indications for and results of combined modality treatment of colorectal cancer. Acta Oncol. 38:1999;7-21.
    • (1999) Acta Oncol , vol.38 , pp. 7-21
    • Gunderson, L.L.1
  • 39
    • 0033018176 scopus 로고    scopus 로고
    • Perioperative radiotherapy in rectal cancer
    • Glimelius B., Pahlman L. Perioperative radiotherapy in rectal cancer. Acta Oncol. 38:1999;23-32.
    • (1999) Acta Oncol , vol.38 , pp. 23-32
    • Glimelius, B.1    Pahlman, L.2
  • 40
    • 0030953484 scopus 로고    scopus 로고
    • Locally advanced primary colorectal cancer: Intraoperative electron and external beam irradiation ± 5-FU
    • Gunderson L.L., Nelson H., Martenson J.A., et al. Locally advanced primary colorectal cancer Intraoperative electron and external beam irradiation ± 5-FU . Int J Radiat Oncol Biol Phys. 37:1997;601-614.
    • (1997) Int J Radiat Oncol Biol Phys , vol.37 , pp. 601-614
    • Gunderson, L.L.1    Nelson, H.2    Martenson, J.A.3
  • 41
    • 0027273350 scopus 로고
    • A phase I/II study of intraoperative radiotherapy in advanced unresectable or recurrent carcinoma of the rectum: A Radiation Therapy Oncology Group (RTOG) study
    • Lanciano R.M., Calkins A.R., Wolkov H.B., et al. A phase I/II study of intraoperative radiotherapy in advanced unresectable or recurrent carcinoma of the rectum A Radiation Therapy Oncology Group (RTOG) study . J Surg Oncol. 53:1993;20-29.
    • (1993) J Surg Oncol , vol.53 , pp. 20-29
    • Lanciano, R.M.1    Calkins, A.R.2    Wolkov, H.B.3
  • 42
    • 0030871015 scopus 로고    scopus 로고
    • Combined modality treatment including intraoperative radiotherapy in locally advanced and recurrent rectal cancer
    • Tveit K.M., Wiig J.N., Olsen D.R., et al. Combined modality treatment including intraoperative radiotherapy in locally advanced and recurrent rectal cancer. Radiother Oncol. 44:1997;277-282.
    • (1997) Radiother Oncol , vol.44 , pp. 277-282
    • Tveit, K.M.1    Wiig, J.N.2    Olsen, D.R.3
  • 43
    • 0025808892 scopus 로고
    • Intraoperative electron beam radiation therapy for primary, locally advanced rectal and rectosigmoid carcinoma
    • Willet C.G., Shellito P.C., Tepper J.E., et al. Intraoperative electron beam radiation therapy for primary, locally advanced rectal and rectosigmoid carcinoma. J Clin Oncol. 9:1991;843-847.
    • (1991) J Clin Oncol , vol.9 , pp. 843-847
    • Willet, C.G.1    Shellito, P.C.2    Tepper, J.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.