The regulation of veratridine-stimulated electrogenic ion transport in mouse colon by neuropeptide Y (NPY), Y 1 and Y 2 receptors

British Journal of Pharmacology

Volumn 146, Issue 5, 2005, Pages 712-722

  Hyland, Niall P ^a   Cox, Helen M ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Mouse colon; Mucosal ion transport; Neuropeptide Y receptors; Submucosal neurons; Veratridine

Indexed keywords

ATROPINE; CARBACHOL; HEXAMETHONIUM; N [2 [1,2 DIHYDRO 3,5(4H) DIOXO 1,2 DIPHENYL 1,2,4 TRIAZOL 4 YL]ETHYL] N2 [[1 [2 [4 [5,11 DIHYDRO 6(6H) OXODIBENZ[B,E]AZEPIN 11 YL] 1 PIPERAZINYL] 2 OXOETHYL]CYCLOPENTYL]ACETYL]ARGININAMIDE; N2 DIPHENYLACETYL N (4 UREIDOMETHYLBENZYL)ARGININAMIDE; NEUROPEPTIDE Y RECEPTOR; NEUROPEPTIDE Y1 RECEPTOR; NEUROPEPTIDE Y2 RECEPTOR; PEPTIDE YY; TETRODOTOXIN; VASOACTIVE INTESTINAL POLYPEPTIDE; VERATRIDINE;

ANIMAL TISSUE; ARTICLE; CHOLINERGIC RECEPTOR BLOCKING; COLON MUCOSA; CONTROLLED STUDY; ION CURRENT; ION TRANSPORT; MOUSE; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; SUBMUCOSA;

ANIMALS; CARBACHOL; COLON; ION TRANSPORT; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEUROPEPTIDE Y; RECEPTORS, NEUROPEPTIDE Y; VASOACTIVE INTESTINAL PEPTIDE; VERATRIDINE;

EID: 27644491312     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/sj.bjp.0706368     Document Type: Article

References (43)

1. ALLESCHER, H.D., KURJAK, M., HUBER, A., TRUDRUNG, P. & SCHUSDZIARRA, V. (1996). Regulation of VIP release from rat enteric nerve terminals: evidence for a stimulatory effect of NO. Am. J. Physiol., 271, G568-G574.
2. BATTERHAM, R.L., COWLEY, M.A., SMALL, C.J., HERZOG, H., COHEN, M.A., DAKIN, C.L., WREN, A.M., BRYNES, A.E., LOW, M.J., GHATEI, M.A., CONE, R.D. & BLOOM, S.R. (2002). Gut hormone PYY(3-36) physiologically inhibits food intake. Nature, 418, 650-654.
3. + depolarization. Regul. Pept., 23, 227-235.
4. CATTERALL, W.A. (1980). Neurotoxins that act on voltage-sensitive sodium channels in excitable membranes. Annu. Rev. Pharmacol. Toxicol., 20, 15-43.
5. COX, H.M. & CUTHBERT, A.W. (1988). Neuropeptide Y antagonises secretagogue evoked chloride transport in rat jejunal epithelium. Pflugers Arch., 413, 38-42.
6. COX, H.M. & CUTHBERT, A.W. (1989). Secretory actions of vasoactive intestinal polypeptide, peptide histidine isoleucine and helodermin in rat small intestine: the effects of putative VIP antagonists upon VIP-induced ion secretion. Regul. Pept., 26, 127-135.
7. COX, H.M., POLLOCK, E.L., TOUGH, I.R. & HERZOG, H. (2001). Multiple Y receptors mediate pancreatic polypeptide responses in mouse colon mucosa. Peptides, 22, 445-452.
8. 4 receptors mediate Y agonist responses in isolated human colon mucosa. Br. J. Pharmacol., 135, 1505-1512.
9. 2 receptors mediate inhibitory tone in murine and human colon mucosae. Neurogastroenterol. Motil., 15, 195-237.
10. 2-receptor-mediated selective inhibition of slow, inhibitory postsynaptic potential in submucous neurons of guinea-pig caecum. Br. J. Pharmacol., 113, 883-888.
11. 2 receptor antagonist. Eur. J. Pharmacol., 384, R3-R5.
12. EKBLAD, E. & SUNDLER, F. (2002). Distribution of pancreatic polypeptide and peptide YY. Peptides, 23, 251-261.
13. FELETOU, M., RODRIGUEZ, M., BEAUVERGER, P., GERMAIN, M., IMBERT, J., DROMAINT, S., MACIA, C, BOURRIENNE, A., HENLIN, J.M., NICOLAS, J.P., BOUTIN, J.A., GALIZZI, J.P., FAUCHERE, J.L., CANET, E. & DUHAULT, J. (1998). NPY receptor subtypes involved in the contraction of the proximal colon of the rat. Regul. Pept., 75-76, 221-229.
14. FERRIER, L., SEGAIN, J., BONNET, C., CHERBUT, C., LEHUR, P., JARRY, A., GALMICHE, J. & BLOTTIERE, H. (2002). Functional mapping of NPY/PYY receptors in rat and human gastrointestinal tract. Peptides, 23, 1765.
15. 1 receptor. J. Neuroendocrinol., 15, 754-760.
16. FURNESS, J.B. (2000). Types of neurons in the enteric nervous system. J.Auton. Nerv. Syst., 81, 87-96.
17. FURNESS, J.B., JONES, C., NURGALI, K. & CLERC, N. (2004). Intrinsic primary afferent neurons and nerve circuits within the intestine. Prog. Neurobiol., 72, 143-164.
18. GOURLET, P., DE NEEF, P., CNUDDE, J., WAELBROECK, M. & ROBBERECHT, P. (1997). In vitro properties of a high affinity selective antagonist of the VIP1 receptor. Peptides, 18, 1555-1560.
19. GRANDT, D., SCHIMICZEK, M., BEGLINGER, C., LAYER, P., GOEBELL, H., EYSSELEIN, V.E. & REEVE, J.R. (1994). Two molecular forms of peptide YY (PYY) are abundant in human blood: characterization of a radioimmunoassay recognizing PYY 1-36 and PYY 3-36. Regul. Pept., 51, 151-159.
20. GREGOR, P., FENG, Y., DECARR, L.B., CORNFIELD, L.J. & MCCALEB, M.L. (1996). Molecular characterization of a second mouse pancreatic polypeptide receptor and its inactivated human homologue. J. Biol. Chem., 271, 27776-27781.
21. HOLLIDAY, N.D., POLLOCK, E.L., TOUGH, I.R. & COX, H.M. (2000). PYY preference is a common characteristic of neuropeptide Y receptors expressed in human, rat, and mouse gastrointestinal epithelia. Can. J. Physiol. Pharmacol., 78, 126-133.
22. HOLZER-PETSCHE, U., PETRITSCH, W., HINTERLEITNER, T., EHERER, A., SPERK, G. & KREJS, G.J. (1991). Effect of neuropeptide Y on jejunal water and ion transport in humans. Gastroenterology, 101, 325-330.
23. 2 antagonism in mouse and human colonie tissues. Br. J. Pharmacol., 139, 863-871.
24. 1 receptor in enteric neurons, endothelial cells, and endocrine-like cells of the rat intestinal tract. J. Histochem. Cytochem., 45, 1643-1650.
25. 2 receptor antagonist, BIIE0246 on neuropeptide Y release. Eur. J. Pharmacol., 396, R1-R3.
26. 2 receptor antagonist BIIE0246 on sympathetic transmitter release in the pig in vivo. Naunyn Schmiedebergs Arch. Pharmacol., 365, 106-111.
27. 2 receptor evidenced by BIIE0246. Eur. J. Pharmacol., 439, 113-119.
28. 1 receptor expression in the epithelium and mucosal nerves of the human colon. Regul. Pept., 83, 11-19.
29. MEDEIROS, M.D. & TURNER, A.J. (1994). Processing and metabolism of peptide-YY: pivotal roles of dipeptidylpeptidase-IV, aminopeptidase-P, and endopeptidase-24.11. Endocrinology, 134, 2088-2094.
30. MICHEL, M.C., BECK-SICKINGER, A., COX, H., DOODS, H.N., HERZOG, H., LARHAMMAR, D., QUIRION, R., SCHWARTZ, T. & WESTFALL, T. (1998). XVI. International Union of Pharmacology recommendations for the nomenclature of neuropeptide Y, peptide YY, and pancreatic polypeptide receptors. Pharmacol. Rev., 50, 143-150.
31. 1 within human colon: evidence for NPY targeting a subpopulation of nitrergic neurons. J. Auton. Nerv. Syst., 67, 168-175.
32. PLASS, H., WACHTER, C. & TURNHEIM, K. (1994). Neurogenic chloride secretion induced by scorpion venom and veratrine in rabbit colon. Naunyn. Schmiedebergs. Arch. Pharmacol., 350, 403-409.
33. PLAYFORD, R.J., DOMIN, J., BEACHAM, J., PARMAR, K.B., TATEMOTO, K., BLOOM, S.R. & CALAM, J. (1990). Preliminary report: role of peptide YY in defence against diarrhoea. Lancet, 335, 1555-1557.
34. RAO, R.K., RIVIERE, P.J., PASCAUD, X., JUNIEN, J.L. & PORRECA, F. (1994). Tonic regulation of mouse ileal ion transport by nitric oxide. J. Pharmacol. Exp. Ther., 269, 626-631.
35. SANG, Q. & YOUNG, H.M. (1996). Chemical coding of neurons in the myenteric plexus and external muscle of the small and large intestine of the mouse. Cell Tissue Res., 284, 39-53.
36. SANG, Q. & YOUNG, H.M. (1998). The identification and chemical coding of cholinergic neurons in the small and large intestine of the mouse. Anat. Rec., 251, 185-199.
37. SERVIN, A.L., ROUYER-FESSARD, C., BALASUBRAMANIAM, A., SAINT, P.S. & LABURTHE, M. (1989). Peptide-YY and neuropeptide-Y inhibit vasoactive intestinal peptide- stimulated adenosine 3′,5′-monophosphate production in rat small intestine: structural requirements of peptides for interacting with peptide-YY-preferring receptors. Endocrinology, 124, 692-700.
38. SHELDON, R.J., MALARCHIK, M.E., BURKS, T.F. & PORRECA, F. (1990). Effects of nerve stimulation on ion transport in mouse jejunum: responses to Veratrum alkaloids. J. Pharmacol. Exp. Ther., 252, 636-642.
39. 2 receptors at peripheral neuroeffector junctions. Br. J. Pharmacol., 132, 861-868.
40. 1 receptors by BIBP3226 in rat and human epithelial preparations. Eur. J. Pharmacol., 310, 55-60.
41. 2 receptor antagonist BIIE0246 on presynaptic inhibition by neuropeptide Y in rat hippocampal slices. Eur. J. Pharmacol., 404, 133-136.
42. 1 receptor antagonist BIBO 3304 and its effect on feeding in rodents. Br. J. Pharmacol., 125, 549-555.
43. YAU, W.M., DORSETT, J.A. & YOUTHER, M.L. (1986). Calcium-dependent stimulation of acetylcholine release by substance P and vasoactive intestinal polypeptide. Eur. J. Pharmacol., 120, 241-243.