Expedient synthesis of substituted imidazoles from nitriles

Tetrahedron Letters

Volumn 46, Issue 48, 2005, Pages 8369-8372

  Frutos, Rogelio P ^a   Gallou, Isabelle ^a   Reeves, Diana ^a   Xu, Yibo ^a   Krishnamurthy, Dhileepkumar ^a   Senanayake, Chris H ^a  

^a BOEHRINGER INGELHEIM PHARMACEUTICALS INC   (United States)

Author keywords

Amino acetals; Copper mediated; Heterocycles; Nitriles; Substituted imidazoles

Indexed keywords

ACETAL DERIVATIVE; COPPER CHLORIDE; IMIDAZOLE DERIVATIVE; NITRILE;

ARTICLE; CHEMICAL REACTION; CYCLIZATION; DRUG SYNTHESIS; METHODOLOGY;

EID: 27644471787     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2005.09.153     Document Type: Article

References (18)

1. For recent reviews see: V.M. Dembitsky, T.A. Gloriozova, and V.V. Poroikov Mini-Rev. Med. Chem. 5 2005 319
2. Z. Jin Nat. Prod. Reports 6 2003 584
3. M.R. Grimmett Comprehensive Heterocyclic Chemistry II Vol. 3 1996 Elsevier Oxford, UK 77
4. For recent reviews see: J.A. Murry Curr. Opin. Drug Discovery Dev. 6 2003 945
5. H. Hoffman, and T. Lindel Synthesis 12 2003 1753
6. B. Dolensky, G. Nam, W.-P. Deng, J. Narayanan, J. Fan, and K.L. Kirk J. Fluorine Chem. 125 2004 501
7. A.M. Van Leusen, J. Wildeman, and O.H. Oldenziel J. Org. Chem. 42 1977 1153
8. A. Lawson J. Chem. Soc. 1957 4225
9. A. Abbotto, S. Bradamante, and G.A. Pagani J. Org. Chem. 61 1996 1761
10. A.I. Meyers, G. Knaus, K. Kamata, and M.E. Ford J. Am. Chem. Soc. 98 1976 567
11. Kolb, H. C.; Kanamarlapudi, R. C.; Richardson, P. F.; Khan, G. U.S. Patent 0153728 A1, 2003.
12. G. Rousselet, P. Capdevielle, and M. Maumy Tetrahedron Lett. 34 1993 6395
13. N.P. Jensen, S.M. Schmitt, T.B. Windholz, and T.Y. Shen J. Med. Chem. 15 1972 341
14. A.S.B. Prasad, T.M. Stevenson, J.R. Citineni, V. Nyzam, and P. Knochel Tetrahedron 53 1997 7237
15. R. Bowman, and F. Aldabbagh Tetrahedron 55 1999 4109
16. D.H. Hua, F. Zhang, J. Chen, and P. Robinson J. Org. Chem. 59 1994 5084
17. J. Rokach, P. Hamel, N.R. Hunter, G. Reader, and C.S. Rooney J. Med. Chem. 22 1979 237
18. S. Iwasaki Helv. Chim. Acta 59 1976 2738