Galanin inhibits gastric acid secretion through a somatostatin-independent mechanism in mice

Peptides

Volumn 25, Issue 8, 2004, Pages 1287-1295

  Piqueras, Laura ^a   Taché, Yvette ^b   Martinez, Vicente ^a,c  

^a UNIVERSIDAD CEU CARDENAL HERRERA   (Spain)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c ASTRAZENECA R AND D   (Sweden)

Author keywords

Acid secretion; Galanin; Immunoneutralization; Pentagastrin; Somatostatin; Somatostatin receptors; SSTR2

Indexed keywords

GALANIN; MONOCLONAL ANTIBODY; PENTAGASTRIN; SOMATOSTATIN; SOMATOSTATIN ANTIBODY; URETHAN;

ANESTHESIA; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; KNOCKOUT MOUSE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; STOMACH ACID SECRETION; WILD TYPE;

ANIMALS; ANTIBODIES, MONOCLONAL; GALANIN; GASTRIC ACID; INSULIN; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PENTAGASTRIN; SOMATOSTATIN; TIME FACTORS;

ANIMALIA;

EID: 4444360115     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.peptides.2004.06.003     Document Type: Article

References (38)

1. Ekblad E., Rokaeus A., Håkanson R., Sundler F. Galanin nerve fibers in the rat gut: distribution, origin and projections. Neuroscience. 16:1985;355-363
2. Fox J.E., Brooks B., McDonald T.J., Barnett W., Kostolanska F., Yanaihara C., et al. Actions of galanin fragments on rat, guinea-pig, and canine intestinal motility. Peptides. 9:1988;1183-1189
3. Hirsch A.B., McCuen R.W., Arimura A., Schubert M.L. Adrenomedullin stimulates somatostatin and thus inhibits histamine and acid secretion in the fundus of the stomach. Regul Pept. 110:2003;189-195
4. Kato S., Korolkiewicz R., Rekowski P., Szyk A., Sugawa Y., Takeuchi K. Inhibition of gastric acid secretion by galanin in rats. Relation to endogenous histamine release. Regul Pept. 74:1998;53-59
5. Burghardt B., Balint A., Zelles T., Vizi E.S., Varga G. Antisecretory effects of galanin and its putative antagonists M15, M35 and C7 in the rat stomach. J Physiol Paris. 94:2000;37-42
6. Komasaka M., Horie S., Watanabe K., Murayama T. Antisecretory effect of somatostatin on gastric acid via inhibition of histamine release in isolated mouse stomach. Eur J Pharmacol. 452:2002;235-243
7. Kwok Y.N., Verchere C.B., McIntosh C.H., Brown J.C. Effect of galanin on endocrine secretions from the isolated perfused rat stomach and pancreas. Eur J Pharmacol. 145:1988;49-54
8. Li P., Chang T.M., Coy D., Chey W.Y. Inhibition of gastric acid secretion in rat stomach by PACAP is mediated by secretin, somatostatin, and PGE(2). Am J Physiol. 278:2000;G121-G127
9. Lindström E., Håkanson R. Neurohormonal regulation of secretion from isolated rat stomach ECL cells: a critical reappraisal. Regul Pept. 97:2001;169-180
10. Lorimer D.D., Benya R.V. Cloning and quantification of galanin-1 receptor expression by mucosal cells lining the human gastrointestinal tract. Biochem Biophys Res Commun. 222:1996;379-385
11. Madaus S., Schusdziarra V., Seufferlein T., Classen M. Effect of galanin on gastrin and somatostatin release from the rat stomach. Life Sci. 42:1988;2381-2387
12. Martinez V. Somatostatin receptors and the regulation of gastric function. In: Taché Y, Goto Y, Ohning G, Yamada T, editors. Gut-brain peptides in the new millennium. Los Angeles: CURE Foundation; 2002. p. 167-78.
13. Martinez V., Curi A.P., Torkian B., Schaeffer J.M., Wilkinson H.A., Walsh J.H., et al. High basal gastric acid secretion in somatostatin receptor subtype 2 knockout mice. Gastroenterology. 114:1998;1125-1132
14. Martinez V, Taché Y. Somatostatin. In: Johnson LR, editor. Encyclopedia of gastroenterology. Amsterdam: Elsevier; 2004. p. 426-33.
15. Martinez V., Yang H., Wong H.C., Walsh J.H., Taché Y. Somatostatin antibody does not influence bombesin-induced inhibition of gastric acid secretion in rats. Peptides. 16:1995;1-6
16. Melander T., Hokfelt T., Rokaeus A., Fahrenkrug J., Tatemoto K., Mutt V. Distribution of galanin-like immunoreactivity in the gastro-intestinal tract of several mammalian species. Cell Tissue Res. 239:1985;253-270
17. Mungan Z., Ozmen V., Ertan A., Coy D.H., Baylor L.M., Rice J.C., et al. Structural requirements for galanin inhibition of pentagastrin-stimulated gastric acid secretion in conscious rats. Eur J Pharmacol. 214:1992;53-57
18. Nagashima T., Takatsuka N., Mochizuki T., Hoshino M., Yanaihara C., Greeley G.H., et al. Effects of galanin-related peptides on gastrin and somatostatin (SRIF) release from the isolated perfused rat stomach. Biomed Res. 13(Suppl 2):1992;329-336
19. Norlen P., Bernsand M., Konagaya T., Hakanson R. ECL-cell histamine mobilization in conscious rats: effects of locally applied regulatory peptides, candidate neurotransmitters and inflammatory mediators. Br J Pharmacol. 134:2001;1767-1777
20. Pham T., Guerrini S., Wong H., Sternini C. Distribution of galanin receptor 1 immunoreactivity in the rat stomach and small intestine. J Comp Neurol. 450:2002;292-302
21. Piqueras L., Corpa J.M., Martinez J., Martinez V. Gastric hypersecretion associated to iodoacetamide-induced mild gastritis in mice. Naunyn Schmiedebergs Arch Pharmacol. 367:2003;140-150
22. Piqueras L., Taché Y., Martinez V. Somatostatin receptor type 2 mediates bombesin-induced inhibition of gastric acid secretion in mice. J Physiol (London). 549:2003;889-901
23. Piqueras L., Taché Y., Martinez V. Peripheral PACAP inhibits gastric acid secretion through somatostatin release in mice. Br J Pharmacol. 142:2004;67-78
24. Prinz C., Sachs G., Walsh J.H., Coy D.H., Wu S.V. The somatostatin receptor subtype on rat enterochromaffinlike cells. Gastroenterology. 107:1994;1067-1074
25. Rokaeus A. Galanin. In: Walsh JH, Dockray GJ, editors. Gut peptides: biochemistry and physiology. New York: Raven Press; 1994. p. 525-52.
26. Rokaeus A., Melander T., Hokfelt T., Lundberg J.M., Tatemoto K., Carlquist M., et al. A galanin-like peptide in the central nervous system and intestine of the rat. Neurosci Lett. 47:1984;161-166
27. Rossowski W.J., Cheng B.L., Jiang N.Y., Coy D.H. Examination of somatostatin involvement in the inhibitory action of GIP, GLP-1, amylin and adrenomedullin on gastric acid release using a new SRIF antagonist analogue. Br J Pharmacol. 125:1998;1081-1087
28. Rossowski W.J., Coy D.H. Inhibitory action of galanin on gastric acid secretion in pentobarbital-anesthetized rats. Life Sci. 44:1989;1807-1813. [Erratum in: Life Sci 1989; 45:105]
29. Schepp W., Prinz C., Tatge C., Hakanson R., Schusdziarra V., Classen M. Galanin inhibits gastrin release from isolated rat gastric G-cells. Am J Physiol. 258:1990;G596-G602
30. Soldani G., Mengozzi G., Della Longa A., Intorre L., Martelli F., Brown D.R. An analysis of the effects of galanin on gastric acid secretion and plasma levels of gastrin in the dog. Eur J Pharmacol. 154:1988;313-318
31. Tatemoto K., Rokaeus A., Jornvall H., McDonald T.J., Mutt V. Galanin - a novel biologically active peptide from porcine intestine. FEBS Lett. 164:1983;124-128
32. Wang Y.F., Mao Y.K., McDonald T.J., Daniel E.E. Distribution of galanin-immunoreactive nerves in the canine gastrointestinal tract. Peptides. 16:1995;237-247
33. Wong H.C., Sternini C., Yang H., Pham T., Walsh J.H. Monoclonal antibody to rat galanin: production, characterization, and in vivo immunoneutralization activity. Hybridoma. 20:2001;109-115
34. Wong H.C., Walsh J.H., Yang H., Taché Y., Buchan A.M. A monoclonal antibody to somatostatin with potent in vivo immunoneutralizing activity. Peptides. 11:1990;707-712
35. Yagci R.V., Alptekin N., Rossowski W.J., Brown A., Coy D.H., Ertan A. Inhibitory effect of galanin on basal and pentagastrin-stimulated gastric acid secretion in rats. Scand J Gastroenterol. 25:1990;853-858
36. Yang H., Wong H., Wu V., Walsh J.H., Taché Y. Somatostatin monoclonal antibody immunoneutralization increases gastrin and gastric acid secretion in urethane-anesthetized rats. Gastroenterology. 99:1990;659-965
37. Zeng N., Kang T., Wen Y., Wong H., Walsh J., Sachs G. Galanin inhibition of enterochromaffin-like cell function. Gastroenterology. 115:1998;330-339
38. Zheng H., Bailey A., Jiang M.H., Honda K., Chen H.Y., Trumbauer M.E., et al. Somatostatin receptor subtype 2 knockout mice are refractory to growth hormone-negative feedback on arcuate neurons. Mol Endocrinol. 11:1997;1709-1717