Developmental toxicology evaluations - Issues with including neurotoxicology and immunotoxicology assessments in reproductive toxicology studies

Toxicological Sciences

Volumn 88, Issue 1, 2005, Pages 24-29

  Ladics, Gregory S ^a   Chapin, Robert E ^b   Hastings, Kenneth L ^c   Holsapple, Michael P ^d   Makris, Susan L ^e   Sheets, Larry P ^f   Woolhiser, Michael R ^g   Burns Naas, Leigh Ann ^b  

^a DUPONT COMPANY   (United States)

^b PFIZER INC   (United States)

^c CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^d ILSI HEALTH AND ENVIRONMENTAL SCIENCES INSTITUTE   (United States)

^e U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^f BAYER CORPORATION   (United States)

^g DOW CHEMICAL COMPANY   (United States)

Author keywords

Combination study; DART; Developmental and reproductive toxicology; Developmental immunotoxicology; Developmental neurotoxicology; DIT; DNT; Hazard identification; Panel discussion; Study design

Indexed keywords

TOXIN;

ARTICLE; CHEMICAL ANALYSIS; CHEMICAL TERATOGENESIS; CONSENSUS DEVELOPMENT; DEVELOPMENTAL DISORDER; DEVELOPMENTAL STAGE; DOSE RESPONSE; FEASIBILITY STUDY; GESTATION PERIOD; HAZARD ASSESSMENT; IMMUNOTOXICITY; LACTATION; NEUROTOXICITY; NONHUMAN; PREDICTION; REPRODUCTIVE TOXICITY; RISK ASSESSMENT; RISK FACTOR; TERATOGEN TESTING; TOXICOKINETICS; WEANING;

ABNORMALITIES, DRUG-INDUCED; ANIMALS; FEMALE; IMMUNE SYSTEM; MALE; MICE; NERVOUS SYSTEM; RATS; REPRODUCTION; TERATOGENS; XENOBIOTICS;

EID: 27644436848     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfi299     Document Type: Article

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