Bacterial surface display library screening by target enzyme labeling: Identification of new human cathepsin G inhibitors

Analytical Biochemistry

Volumn 346, Issue 2, 2005, Pages 258-267

  Jose, Joachim ^a   Betscheider, Dirk ^a   Zangen, Dirk ^a,b  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b PFIZER INC   (United States)

Author keywords

Autodisplay; Cathepsin G; Drug discovery; FACS; Labeling; Peptide libraries; Screening

Indexed keywords

CELL MEMBRANES; DRUG PRODUCTS; ENZYMES; ESCHERICHIA COLI; FLOW CYTOMETRY; FLUORESCENCE; LABELING; LIBRARIES; PEPTIDES; SCREENING;

AUTODISPLAY; CATHEPSIN G; DRUG DISCOVERY; FACS; PEPTIDE LIBRARY;

CYTOLOGY;

BIOTIN; CATHEPSIN G; CATHEPSIN G INHIBITOR; CYSTEINE PROTEINASE INHIBITOR; FLUORESCEIN ISOTHIOCYANATE; PEPTIDE; PEPTIDE LIBRARY; STREPTAVIDIN; UNCLASSIFIED DRUG;

AFFINITY LABELING; ARTICLE; CELL CLONE; CELL DIFFERENTIATION; CELL SELECTION; CELL STRUCTURE; CELL SURFACE; CONTROLLED STUDY; DNA SEQUENCE; ENZYME STRUCTURE; ESCHERICHIA COLI; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN TARGETING; WHOLE CELL;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 27644435170     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2005.08.019     Document Type: Article

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