Evidence for the hydrophobic cavity of heme oxygenase-1 to be a CO-trapping site

Biochemical and Biophysical Research Communications

Volumn 338, Issue 1, 2005, Pages 584-589

  Migita, Catharina T ^a   Togashi, Satoko ^a   Minakawa, Miki ^a   Zhang, Xuhong ^b   Yoshida, Tadashi ^b  

^a YAMAGUCHI UNIVERSITY   (Japan)

^b YAMAGATA UNIVERSITY   (Japan)

Author keywords

CO inhibition; CO trapping site; Heme degradation; Heme oxygenase; Kinetics; Verdoheme conversion

Indexed keywords

2 PROPANOL; CARBON MONOXIDE; FERREDOXIN NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE REDUCTASE; HEME OXYGENASE 1; HEMOPROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; UNCLASSIFIED DRUG; VERDOHEME;

ABSORPTION SPECTROSCOPY; ARTICLE; CONTROLLED STUDY; CRYSTALLOGRAPHY; ESCHERICHIA COLI; HYDROPHOBICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; SYNECHOCYSTIS;

2-PROPANOL; ANIMALS; ASCORBIC ACID; BACTERIAL PROTEINS; BINDING SITES; CARBON MONOXIDE; HEME; HEME OXYGENASE-1; HUMANS; HYDROPHOBICITY; MEMBRANE PROTEINS; RATS; SYNECHOCYSTIS;

CYANOBACTERIA; ESCHERICHIA COLI; SYNECHOCYSTIS; SYNECHOCYSTIS SP. PCC 6803;

EID: 27544506562     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2005.08.045     Document Type: Article

References (29)

1. R. Tenhunen, H.S. Marver, and R. Schmid The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase Proc. Natl. Acad. Sci. USA 61 1968 748 755
2. T. Yoshida, M. Noguchi, and G. Kikuchi The step of carbon monoxide liberation in the sequence of heme degradation catalyzed by the reconstituted microsomal heme oxygenase system J. Biol. Chem. 257 1982 9345 9348
3. P. Vigne, E. Feolde, A. Ladoux, D. Duval, and C. Frelin Contributions of NO synthase and heme oxygenase to cGMP formation by cytokine and hemin-treated brain capillary endothelial cells Biochem. Biophys. Res. Commun. 214 1995 1 5
4. L. Xue, G. Farrugia, S.M. Miller, C.D. Ferris, S.H. Snyder, and J.H. Szurszewski Carbon monoxide and nitric oxide as coneurotransmitters in the enteric nervous system: evidence from genomic deletion of biosynthetic enzymes Proc. Natl. Acad. Sci. USA 97 2000 1851 1855
5. M. Suematsu, S. Kashiwagi, T. Sano, N. Goda, Y. Shinoda, and Y. Ishimura Carbon monoxide as an endogenous modulator of hepatic vascular perfusion Biochem. Biophys. Res. Commun. 205 1994 1333 1337
6. R. Zakhary, K.D. Poss, S.R. Jaffrey, C.D. Ferris, S. Tonegawa, and S.H. Snyder Targeted gene deletion of heme oxygenase2 reveals neural role for carbon monoxide Proc. Natl. Acad. Sci. USA 94 1997 13853 14848
7. D.E. Barañano, and S.H. Snyder Neural roles for heme oxygenase: contrasts to nitric oxide synthase Proc. Natl. Acad. Sci. USA 98 2001 10996 11002
8. A. Wilks, and M.P. Schmitt Expression and characterization of a heme oxygenase (Hmu O) from Corynebacterium diphtheriae J. Biol. Chem. 273 1998 837 841
9. W. Zhu, A. Wilks, and I. Stojiljkovic Degradation of heme in Gram-negative bacteria: the product of the hem O gene of Neisseriae is a heme oxygenase J. Bacteriol. 182 2000 6783 6790
10. T. Muramoto, N. Tsurui, M.J. Terry, A. Yokota, and T. Kohchi Expression and biochemical properties of a ferredoxin-dependent heme oxygenase required for phytochrome chromophore synthesis Plant Physiol. 130 2002 1958 1966
11. C.T. Migita, X. Zhang, and T. Yoshida Expression and characterization of cyanobacterium heme oxygenase, a key enzyme in the phycobilin synthesis: properties of the heme complex of recombinant active enzyme Eur. J. Biochem. 270 2003 687 698
12. X. Zhang, M. Sato, M. Sasahara, C.T. Migita, and T. Yoshida Unique features of recombinant heme oxygenase of Drosophila melanogaster compared with those of other heme oxygenases studied Eur. J. Biochem. 271 2004 1713 1714
13. X. Zhang, C.T. Migita, M. Sato, M. Sasahara, and T. Yoshida Protein expressed by the ho2 gene of the cyanobacterium Synechocystis sp. PCC 6803 is a true heme oxygenase-properties of the heme and enzyme complex FEBS J. 272 2005 1012 1022
14. T. Yoshida, and C.T. Migita Mechanism of heme degradation by heme oxygenase J. Inorg. Biochem. 82 2000 33 41
15. C. Colas, and P.R. Ortiz de Montellano Autocatalytic radical reactions in physiological prosthetic heme modification Chem. Rev. 103 2003 2305 2332
16. T. Yoshida, and G. Kikuchi Purification and properties of heme oxygenase from pig spleen microsomes J. Biol. Chem. 253 1978 4224 4229
17. T. Yoshida, and G. Kikuchi Features of the reaction of heme degradation catalyzed by the reconstituted microsomal heme oxygenase system J. Biol. Chem. 253 1978 4230 4236
18. B.A. Schacter, E.B. Nelson, H.S. Marver, and B.S.S. Masters Immunochemical evidence for an association of heme oxygenase with the microsomal electron transport system J. Biol. Chem. 253 1972 3601 3607
19. R. Davydov, U. Fofman, H. Fujii, T. Yoshida, M. Ikeda-Saito, and B.M. Hoffman Catalytic mechanism of heme oxygenase through EPR and ENDOR of cryoreduced oxy-heme oxygenase and its Asp 140 mutant J. Am. Chem. Soc. 124 2002 1798 1808
20. K. Mansfield Matera, S. Takahashi, H. Fujii, H. Zhou, K. Ishikawa, K.T. Yoshimura, D.L. Rousseau, T. Yoshida, and M. Ikeda-Saito Oxygen and one reducing equivalent are both required for the conversion of α-hydroxyhemin to verdoheme in heme oxygenase J. Biol. Chem. 271 1996 6618 6624
21. J. Cornejo, R.D. Willows, and S.I. Beale Phytobilin biosynthesis:cloning and expression of a gene encoding soluble ferredoxin-dependent heme oxygenase from Synechocystis sp. PCC 6803 Plant J. 15 1998 99 107
22. C.T. Migita, K. Mansfield Matera, M. Ikeda-Saito, J.S. Olson, H. Fujii, T. Yoshimura, H. Zhou, and T. Yoshida The oxygen and carbon monoxide reactions of heme oxygenase J. Biol. Chem. 273 1998 945 949
23. M. Sugishima, H. Sakamoto, M. Noguchi, and K. Fukuyama CO-trapping site in heme oxygenase revealed by photolysis of its CO-bound heme complex: mechanism of escaping from product inhibition J. Mol. Biol. 341 2004 7 13
24. M. Sugishima, C.T. Migita, X. Zhang, T. Yoshida, and K. Fukuyama Crystal structure of heme oxygenase-1 from cyanobacterium Synechocystis sp. PCC 6803 in complex with heme Eur. J. Biochem. 271 2004 4517 4525
25. S. Yamano, O.W. McBride, J.P. Hardwick, H.V. Gelboin, and F.J. Gonzalez Human NADPH-P450 oxidoreductase: complementary DNA cloning, sequence and vaccina virus-mediated expression and localization of the CYPOR gene to chromosome 7 Mol. Pharmacol. 36 1989 83 88
26. K. Mansfield Matera, H. Zhou, C.T. Migita, S.E. Hobert, K. Ishikawa, K. Katakura, H. Maeshita, T. Yoshida, and M. Ikeda-Saito Histidine-132 does not stabilize a distal water ligand and is not an important residue for the enzyme activity in heme oxygenase-1 Biochemistry 36 1997 4909 4915
27. T. Hase, S. Mizutani, and Y. Mukohata Expression of maize ferredoxin cDNA in Escherichia coli Plant Physiol. 97 1991 1395 1401
28. + oxidoreductase with photosynthetic and non-photosynthetic ferredoxin isoproteins Plant Physiol. 123 2000 1037 1045
29. Y. Liu, and P.O. OrtizdeMotellano Reaction intermediates and single turnover rate constants for the oxidation of heme by human heme oxygenase-1 J. Biol. Chem. 275 2000 5297 5307