Immunolocalization of RANKL is increased and OPG decreased during dietary magnesium deficiency in the rat

Nutrition and Metabolism

Volumn 2, Issue , 2005, Pages

  Rude, Robert K ^a   Gruber, Helen E ^b   Wei, Livia Y ^a   Frausto, Angelica ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b CAROLINAS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

OSTEOCLAST DIFFERENTIATION FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE DEVELOPMENT; BONE MASS; CELL COUNT; CONTROLLED STUDY; DIET; DIETARY INTAKE; FEMALE; IMMUNOCYTOCHEMISTRY; IMMUNOLOCALIZATION; MAGNESIUM DEFICIENCY; NONHUMAN; NUTRIENT SUPPLY; OSTEOCLAST; OSTEOPOROSIS; PROTEIN LOCALIZATION; RAT; RISK FACTOR; STAINING; TIBIA;

ANIMALIA;

EID: 27544484519     PISSN: 17437075     EISSN: 17437075     Source Type: Journal    
DOI: 10.1186/1743-7075-2-24     Document Type: Article

References (31)

1. Nutrient Requirements of Laboratory Animals 4th edition. Washington, DC: National Academy Press; 1995:13.
2. Kenney MA, McCoy H, Williams L: Effects of magnesium deficiency on strength, mass and composition of rat femur. Calcif Tissue Int 1994, 54:44-49.
3. Boskey AL, Rimnac CM, Bansal M, et al.: Effect of short-term hypomagnesemia on the chemical and mechanical properties of rat bone. J Orthpaedic Res 1992, 10:774-783.
4. Mirra JM, Alcock NW, Shils ME, Tannenbaum P: Effects of calcium and magnesium deficiencies on rat skeletal development and parathyroid gland area. Magnesium 1982, 1:16-33.
5. Carpenter TO, Mackowiak SJ, Troiano N, Gundberg CM: Osteocalcin and its message: relationship to bone histology in magnesium-deprived rats. Am J Physiol 1992, 263:E107-E114.
6. Rude RK, Kirchen ME, Gruber HE, Meyer MH, Luck JS, Crawford DL: Magnesium deficiency-induced osteoporosis in the rat: uncoupling of bone formation and bone resorption. Magnes Res 1999, 12:257-267.
7. Rude RK, Gruber HE, Wei LY, Frausto A, Mills BG: Magnesium Deficiency: Effect on bone and mineral metabolism in the mouse. Calcif Tissue Int 2003, 72:32-41.
8. Gruber HE, Rude RK, Wei LY, Frausto A, Mills BG, Norton HJ: Magnesium deficiency: effect on bone mineral density in the mouse appendicular skeleton. BMC Musculoskeletal Disorders 2003, 4:7-11.
9. Rude RK, Gruber HE, Norton HJ, Wei LY, Frausto A, Mills BG: Bone loss induced by dietary magnesium reduction to 10% of the nutrient requirement in rats is associated with increased release of substance P and tumor necrosis factor-α. J Nutr 2004, 134:79-85.
10. Robert RK, Gruber HE, Norton HJ, Wei LY, Frausto A, Kilburn J: Dietary Magnesium Reduction to 25% of Nutrient Requirement Disrupts Bone and Mineral Metabolism in the Rat. Bone 2005, 37:211-219.
11. Dietary Reference Intakes for calcium, phosphorus, magnesium, vitamin D, and fluoride Washington, DC National Academy Press; 1997:190-249.
12. Department of Health and Human services: Dietary intake of selected minerals for the United States Population: 1999-2000 341:1-6. April 27, 2004
13. Cleveland LE, Goldman JD, Borrude LG: Data tables: results from USDA 1994 continuing survey of food intakes by individuals and 1994 diet and health knowledge survey. Beltsville, MD: Agricultural Research Service, U.S. Department of Agriculture; 1994.
14. Yano K, Heilbrun LK, Wasnich RD, Hankin JH, Vogel JM: The relationship between diet and bone mineral content of multiple skeletal sites in elderly Japanese American men and women living in Hawaii. Am J Clin Nutr 1985, 42:877-888.
15. New SA, Bolton-Smith C, Grubb DA, Reid DM: Nutritional influences on bone mineral density: a cross-sectional study in premenopausal women. Am J Clin Nutr 1997, 65:1831-1839.
16. New SA, Robins SP, Campbell MK, et al.: Dietary influences on bone mass and bone metabolism: further evidence of a positive link between fruit and vegetable consumption and bone health? Am J Clin Nutr 2000, 71:142-151.
17. Tucker KL, Hannan MT, Chen H, et al.: Potassium, magnesium and fruit and vegetable intakes are associated with greater bone mineral density in elderly men and women. Am J Clin Nutr 1999, 69:727-736.
18. Carpenter TO, Barton CN, Park YK: Usual dietary magnesium intake in NHANES III is associated with femoral bone mass. J Bone Min Res 2000, 15(Suppl 1):S292.
19. Hofbauer LC, Heufelder AE: The role of receptor activator of nuclear factor-kB ligand and osteoprotegerin in the pathogenesis and treatment of metabolic bone diseases. J Clin Endocrinol Metab 2000, 85:2355-2363.
20. Manolagas SC: Birth and death of bone cells: basic regulatory mechanisms and implications for the pathogenesis and treatment of osteoporosis. Endocrine Reviews 2000, 21:115-137.
21. Hofbauer LC, Heufelder AE: Role of receptor activator of nuclear factor-kB ligand and osteoprotegein in bone cell biology. J Mol Med 2001, 79:243-252.
22. Horowitz MC, Xi Y, Wilson K, Kacena MA: Control of osteoclastogenesis and bone resorption by members of the TNF family of receptors and ligands. Cytokine Growth Factor Reviews 2001, 12:9-18.
23. Feng X: Regulatory roles and molecular signaling of TNF family members in osteoclasts. Gene 2005, 350:1-13.
24. Mills BG, Frausto A: Cytokines expressed in multinucleated cells: Paget's disease and giant cell tumors versus normal bone. Calcif Tissue Int 1997, 61:16-21.
25. Mills BG, Frausto A, Brien E: Cytokines associated with the pathophysiology of aggressive fibromatosis. J Orthopaedic Res 2000, 18:655-662.
26. Weglicki WB, Dickens BF, Wagner TL, Chemielinska JJ, Phillips TM: Immunoregulation by neuropeptides in magnesium deficiency: ex vivo effect of enhanced substance P production on circulation T lymphocytes from magnesium-deficient mice. Magnes Res 1996, 9:3-11.
27. Rude RK, Oldham SB, Sharp CF, Singer FR: Parathyroid hormone secretion in magnesium deficiency. J Clin Endocrinol Metab 1978, 47:800-806.
28. Fatemi S, Ryzen E, Flores J, Endres DB, Rude RK: Effect of experimental human magnesium depletion on parathyroid hormone secretion and 1,25-dihydroxyvitamin D metabolism. J Clin Endocrinol Metab 1991, 73:1067-1072.
29. Liu CC, Yeh JK, Aloia JF: Magnesium directly stimulates osteoblast proliferation. J Bone Min Res 1988, 3:S104.
30. Cohen L, Laor A, Kitzes R: Bone magnesium, crystallinity index and state of body magnesium in subjects with senile osteoporosis, maturity-onset diabetes and women treated with contraceptive preparations. Magnesium 1983, 2:70-75.
31. Dorup I, Flyvbjerg A, Everts ME, Clausen T: Role of insulin-like growth factor-1 and growth hormone in growth inhibition induced by magnesium and zinc deficiencies. Brit J Nutr 1991, 66:505-521.