Bacterial transfer of large functional genomic DNA into human cells

Gene Therapy

Volumn 12, Issue 21, 2005, Pages 1559-1572

  Laner, A ^a   Goussard, S ^b   Ramalho, A S ^c   Schwarz, T ^a   Amaral, M D ^c,d   Courvalin, P ^b   Schindelhauer, D ^a,e   Grillot Courvalin, C ^b  

^a UNIVERSITY OF MUNICH   (Germany)

^b INSTITUT PASTEUR   (France)

^c NATIONAL INSTITUTE OF HEALTH DR RICARDO JORGE   (Portugal)

^d UNIVERSITY OF LISBON   (Portugal)

^e TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

Bacterial E. coli vector; CFTR; Gene delivery; Human artificial chromosome

Indexed keywords

DNA FRAGMENT; EPIDERMAL GROWTH FACTOR RECEPTOR; GENOMIC DNA; SATELLITE DNA; TRANSMEMBRANE CONDUCTANCE REGULATOR;

ARTICLE; ARTIFICIAL CHROMOSOME; BACTERIAL GENE; BACTERIAL STRAIN; CELL INVASION; CENTROMERE; CONTROLLED STUDY; ELECTROPORATION; ESCHERICHIA COLI; FLOW CYTOMETRY; GENE DELIVERY SYSTEM; GENE FUNCTION; GENE LOCUS; GENE THERAPY; GENE TRANSFER; GENE VECTOR; GENETIC ENGINEERING; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; MAMMAL CELL; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PLASMID; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PULSED FIELD GEL ELECTROPHORESIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SPLICING; SOUTHERN BLOTTING;

CELL LINE, TUMOR; CHROMOSOMES, ARTIFICIAL, BACTERIAL; CHROMOSOMES, ARTIFICIAL, HUMAN; CLONE CELLS; DNA, RECOMBINANT; ELECTROPORATION; ESCHERICHIA COLI; FLOW CYTOMETRY; GENE EXPRESSION; GENE THERAPY; GENETIC VECTORS; GENOME, BACTERIAL; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; LUNG NEOPLASMS; RECOMBINATION, GENETIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SARCOMA;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; MAMMALIA;

EID: 27544472925     PISSN: 09697128     EISSN: 14765462     Source Type: Journal    
DOI: 10.1038/sj.gt.3302576     Document Type: Article

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