TRP cation channels as markers for prostate carcinoma and a possible target molecules for drugs;TRP-kationenkanäle als marker für das prostatakarzinom und als mögliche zielmoleküle für medikamente

BioSpektrum

Volumn 11, Issue 5, 2005, Pages 620-622

  Flockerzi, Veit ^a,b   Wissenbach, Ulrich ^a  

^a SAARLAND UNIVERSITY   (Germany)

^b SAARLAND UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 27544470946     PISSN: 09470867     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Short Survey

References (12)

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2. Jordt, S.E., Bautista, D.M., Chuang, H., McKemy, D.D., Zygmunt, P.M., Högestätt, E.D., Meng, I.D., Julius, D. (2004): Mustard oil and cannabinoids excite sensory nerve fibres through the TRP channel ANK-TM1. Nature 427: 260-265.
3. Macpherson, L.J., Geierstanger, B.H., Viswanath, V., Bandell, M., Eid, S.R., Hwang, S., Patapoutian, A. (2005): The pungency of garlic: activation of TRPA1 and TRPV1 in response to allicin. Current Biology 15: 929-934.
4. West, R.J., Andrew, Y., Church, D.L., Lambie, E.J. (2001): The C.elegans gon-2 gene encodes a putative TRP cation channel protein required for mitotic cell cycle progression. Gene 266: 103-110.
5. Okamura, Y., Nishino, A., Murata, Y., Nakajo, K., Iwaski, H., Ohtuska, Y., Tanak-Kunishima, M., Takahasi, N., Hara, Y., Yoshida, T., Nishida, M., Okado, H., Watari, H., Meinertzhagen, I.A., Satoh, N., Takahashi, K., Satou, Y., Okada, Y., Mori, Y. (2005): Comprehensive analysis of the ascidian genome reveals novel insights into the molecular evolution of ion channel genes. Physiol. Genomics 22: 269-282.
6. Duncan, L.M., Deeds, J., Hunter, J., Shao, J., Holmgren, L.M., Woolf, E.A., Tepper, R.I., Shyjan, A.W. (1998): Down regulation of the novel gene Melastatin correlates with potential for melanoma metastasis. Cancer Research 58: 1515-1520.
7. Wissenbach, U., Niemeyer, B.A., Fixemer, T., Schneidewind, A., Trost, C., Cavalié, A., Reuss, K., Messe, E., Bonkhoff, H., and Flockerzi, V. (2001): Expression of CaT-Like, a novel calcium selective channel, correlates with the malignancy of prostate cancer. J. Biol. Chem. 276: 19461-19468.
8. Tsavaler,L., Shapero, M.H., Morkowski, S., Laus R. (2001): Trp-p8, a novel prostate-specific gene, is upregulated in prostate cancer and other malignancies and shares high homology with transient receptor potential calcium channel proteins. Cancer Research 61: 3760-3769.
9. Fixemer, T., Wissenbach, U., Flockerzi, V., and Bonkhoff, H. (2003): Expression of the Ca selective cation channel TRPV6 in human prostate cancer: a novel prognostic marker for tumor progression. Oncogene 49: 7858-7861.
10. 2+ current and TRPV6 channels in lymph node prostate cancer cells. J. Biol. Chem. 278: 50872-50879.
11. 2+ entry by protein kinase C and calmodulin. Proc. Natl. Acad. Sci U.S.A. 98: 3600-3605.
12. Voets, T., Droogmans, G., Wissenbach, U., Jannsens, A., Flockerzi, V. and Nilius, B. (2004): The principle of temperature-dependent gating in cold-and heat-sensitive TRP channels. Nature 430: 748-54.