HIV-infected progressors and long-term non-progressors differ in their capacity to respond to an A-class CpG oligodeoxynucleotide

AIDS

Volumn 19, Issue 16, 2005, Pages 1924-1925

  Saez, Raquel ^a   Echaniz, Pilar ^a   De Juan, Maria Dolores ^a   Iribarren, José Antonio ^a   Cuadrado, Emilio ^a  

^a HOSPITAL DONOSTIA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; GAMMA INTERFERON; OLIGODEOXYNUCLEOTIDE;

ARTICLE; CELL COUNT; CELLULAR IMMUNITY; CLINICAL ARTICLE; CONTROLLED STUDY; CPG ISLAND; CYTOKINE PRODUCTION; DISEASE COURSE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INNATE IMMUNITY; NATURAL KILLER CELL; PRIORITY JOURNAL; T LYMPHOCYTE SUBPOPULATION;

EID: 27544465418     PISSN: 02699370     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.aids.0000191229.52385.5f     Document Type: Article

References (15)

1. Levy JA. The importance of the innate immune system in controlling HIV infection and disease. Trends Immunol 2001; 22:312-316.
2. Scott-Algara D, Truong LX, Versmisse P, David A, Luong TT, Nguyen NV, et al. Increased NK cell activity in HIV-1 exposed but uninfected vietnamese intravascular drug users. J Immunol 2003; 171:5663-5667.
3. Young-J, Kanzler H, Soumelis V, Gilliet M. Dendritic cell lineage, plasticity and cross regulation. Nat Immunol 2002; 2:585-589.
4. Soumelis V, Scott I, Gheyas F, Bouhour D, Cozon G, Cotte L, et al. Depletion of circulating natural type interferon-producing cells in HIV-infected AIDS patients. Blood 2001; 98:906-912.
5. Vollmer J, Weeratna R, Payette P, Jurk M, Schetter C, Laucht M, et al. Characterization of three CpG oligodeoxynucleotide classes with distinct immunstimulatory activities. Eur J Immunol 2004; 34:251-262.
6. Cho HJ, Hayashi, Datta SK, Takabayashi K, Van Uden JH, Horner A, et al. IFN-type 1 promote priming of antigen-specific CD8+ and CD4+ T lymphocytes by stimulatory DNA-based vaccines. J Immunol 2002; 168:4907-4913.
7. Ayash-Rashkovsky M, Weisman Z, Diveley J, Moss RB, Bentwich Z, Borkow G. Generation of TH1 immune responses to inactivated, gp120-depleted HIV-1 in mice with a dominant Th2 biased immune profile via immunostimulatory oligonucleotides - relevance to AIDS vaccines in developing countries. Vaccine 2002; 20:2684-2692.
8. Tritel M, Stoddard AM, Flynn BJ, Darrah PA, Wu CY, Wille U, et al. Prime-boost vaccination with HIV-1 gag protein and CpG oligodeoxynucleotide, followed by adenovirus, induces sustained and robust humoral and cellular immune response. J Immunol 2003; 171:2538-2547.
9. Lore K, Betts MR, Brenchley JM, Kuruppu J, Khojasteh S, Perfetto S, et al. Toll like receptors ligands modulate dendritic cells to augment cytomegalovirus- and HIV-1-specific T cell responses. J Immunol 2003; 171:4320-4328.
10. Verthelyi D, Ishii KJ, Gursel M, Takeshita F, Klinman DM. Human peripheral blood cells differentially recognize and respond to two distnct CpG motifs. J Immunol 2001; 166:2372-2377.
11. Sivori S, Falco M, Della Chiesa M, Carlomagno S, Vitale M, Moretta L, Moretta A. CpG and double stranded RNA trigger human NK cells by toll like receptors: induction for cytokine release and cytotoxicity against tumors and dendritic cells. Proc Natl Acad Sci U S A 2004; 101:10116-10121.
12. Pan P-Y, Gu P, Li Q, Xu D, Weber K, Chen SH. Regulation of dendritic cell function by NK cells: mechanism underlying the synergism in the combination therapy of IL-12 and 4-1BB activation. J Immunol 2004; 172:4779-4789.
13. Martin MP, Gao X, Lee JH, Nelson GW, Detels R, Goedert JJ, et al. Epistatic interaction between KIR3DS1 and HLA-B delays the progression to AIDS. Nat Genet 2002; 31:429-433.
14. Alter G, Malenfant JM, Delabre RM, Burgett NC, Yu XG, Lichterfeld M, et al. Increased natural killer cell activity in viremic HIV-1 infection. J Immunol 2004; 173:5305-5311.
15. Azzoni L, Papasavvas E, Cheimi J, Kostman JR, Mounzer K, Ondercin J, et al. Sustained impairment of IFNγ secretion in suppressed HIV-infected patients despite mature NK recovery: evidence for a defective reconstitution of innate immunity. J Immunol 2002; 168:5764-5770.