Asbestos-induced lung inflammation and epithelial cell proliferation are altered in myeloperoxidase-null mice

Cancer Research

Volumn 65, Issue 21, 2005, Pages 9670-9677

  Haegens, Astrid ^a   Van Der Vliet, Albert ^a   Butnor, Kelly J ^a   Heintz, Nicholas ^a   Taatjes, Douglas ^a   Hemenway, David ^b   Vacek, Pamela ^a   Freeman, Bruce A ^c   Hazen, Stanley L ^d   Brennan, Marie Luise ^d   Mossman, Brooke T ^a  

^a UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

^b University of Vermont   (United States)

^c UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^d LERNER RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASBESTOS FIBER; CARCINOGEN; CHRYSOTILE; CYCLIN D1; KI 67 ANTIGEN; MYELOPEROXIDASE; OXIDIZING AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOSYNTHESIS; CELL ASSAY; CELL CYCLE; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ASSAY; EXPERIMENTAL MODEL; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; INHALATION; KNOCKOUT MOUSE; LEUKOCYTE COUNT; LEUKOCYTE DIFFERENTIAL COUNT; LUNG ALVEOLUS EPITHELIUM; LUNG ALVEOLUS MACROPHAGE; LUNG DEPOSIT; LUNG LAVAGE; LYMPHOCYTE COUNT; MALE; MOUSE; NEUTROPHIL; NONHUMAN; OXIDATIVE STRESS; PNEUMONIA; PRIORITY JOURNAL; REGULATORY MECHANISM;

ANIMALS; ASBESTOS; BRONCHOALVEOLAR LAVAGE FLUID; CELL GROWTH PROCESSES; CYCLIN D1; EPITHELIAL CELLS; INHALATION EXPOSURE; MALE; MICE; MICE, INBRED C57BL; PEROXIDASE; PNEUMONIA;

EID: 27544456354     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-05-1751     Document Type: Article

References (47)

1. Quinlan T, Marsh J, Janssen Y, et al. Dose responsive increases in pulmonary fibrosis after inhalation of asbestos. Am J Respir Crit Care Med 1994;149:795-802.
2. Zhao Q, Simpson LG, Driscoll KE, Leikauf GD. Chemokine regulation of ozone-induced neutrophil and monocyte inflammation. Am J Physiol 1998;274: L39-46.
3. Hubbard AK, Timblin CR, Shukla A, Rincon M, Mossman BT. Activation of NF-κB-dependent gene expression by silica in lungs of luciferase reporter mice. Am J Physiol Lung Cell Mol Physiol 2002;282:L968-75.
4. Mossman B, Churg A. Mechanisms in the pathogenesis of asbestosis and silicosis. Am J Respir Crit Care Med 1998;157:1666-80.
5. Craighead J, Abraham J, Churg A, et al. The pathology of asbestos-associated diseases of the lungs and pleural cavities: diagnostic criteria and proposed grading schema Report of the Pneumoconiosis Committee of the College of American Pathologists and the National Institute for Occupational Safety and Health. Arch Pathol Lab Med 1982;106:544-96.
6. Manning C, Vallyathan V, Mossman B. Diseases caused by asbestos: mechanisms of injury and disease development. Int Immunopharmacol 2002;2:191-200.
7. Eiserich JP, Hristova M, Cross CE, et al. Formation of nitric oxide-derived inflammatory oxidants by myeloperoxidase in neutrophils. Nature 1998;391:393-7.
8. Gaut JP, Byun J, Tran HD, et al. Myeloperoxidase produces nitrating oxidants in vivo. J Clin Invest 2002; 109:1311-9.
9. van der Vliet A, Eiserich JP, Shigenaga M, Cross CE. Reactive nitrogen species and tyrosine nitration in the respiratory tract epiphenomina or pathobiological mechanism of disease. Am J Respir Crit Care Med 1999;160:1-9.
10. Tanaka S, Choe N, Hemenway D, Zhu S, Matalon S, Kagan E. Asbestos inhalation induces reactive nitrogen species and nitrotyrosine formation in the lungs and pleura of the rat. J Clin Invest 1998;102:445-54.
11. Baldus S, Eiserich JP, Mani A, et al. Endothelial transcytosis of myeloperoxidase confers specificity to vascular ECM proteins as targets of tyrosine nitration. J Clin Invest 2001;108:1759-70.
12. Eiserich JP, Baldus S, Brennan ML, et al. Myeloperoxidase, a leukocyte-derived vascular NO oxidase. Science 2002;296:2391-4.
13. Mossman BT, Craighead JE, MacPherson BV. Asbestos-induced epithelial changes in organ cultures of hamster trachea: inhibition by retinyl methyl ether. Science 1980;207:311-3.
14. Miller MD, Krangel MS. Biology and biochemistry of the chemokines: a family of chemotactic and inflammatory cytokines. Crit Rev Immunol 1992;12:17-46.
15. Shukla A, Gulumian M, Hei T, Kamp D, Rahman Q, Mossman B. Multiple roles of oxidants in the pathogenesis of asbestos-induced diseases. Free Radic Biol Med 2003;34:1117-29.
16. Robledo R, Buder-Hoffmann S, Cummins A, Walsh E, Taatjes D, Mossman B. Increased phosphorylated ERK immunoreactivity associated with proliferative and morphologic lung alterations following chrysotile asbestos inhalation in mice. Am J Pathol 2000;156: 1307-16.
17. BeruBe K, Quinlan T, Moulton G, et al. Comparative proliferative and histopathologic changes in rat lungs after inhalation of chrysolite or crocidolite asbestos. Toxicol Appl Pharmacol 1996;137:67-74.
18. Smith C, Batcher S, Catanzaro A, Abraham J, Phalen R. Sequence of bronchoalveolar lavage and histopathologic findings in rat lungs early in inhalation asbestos exposure. J Toxicol Environ Health 1987;20:147-61.
19. Yang KY, Arcaroli JJ, Abraham E. Early alterations in neutrophil activation are associated with outcome in acute lung injury. Am J Respir Crit Care Med 2003; 167:1567-74.
20. Crapo J, Miller F, Mossman B, Pryor W, Kiley J. NHLBI workshop summary. Environmental lung diseases. Relationship between acute inflammatory responses to air pollutants and chronic lung disease. Am Rev Respir Dis 1992;145:1506-12.
21. Brennan M, MM A, Shih D, et al. Increased atherosclerosis in myeloperoxidase-deficient mice. J Clin Invest 2001;107:419-30.
22. Campbell W, Huggins C, Wylie A. U.S. Bureau of Mines Report of Investigations, No. 8452; 1980.
23. Hemenway D, MacAskill S. Design, development and test results of a horizontal flow, facility. Am Ind Hyg Assoc J 1982;43:874-9.
24. Scholzen T, Gerdes J. The Ki-67 protein: from the known and the unknown. J Cell Physiol 2000;182:311-22.
25. Brody A, Overby L. Incorporation of tritiated thymidine by epithelial and interstitial cells in bronchiolar-alveolar regions of asbestos-exposed rats. Am J Pathol 1989;134:133-40.
26. Mossman B, Gee J. Asbestos related disease. N Eng] J Med 1989;320:1721-30.
27. Mossman B, Bignon J, Corn M, Seaton A, Gee J. Asbestos: scientific developments and implications for public policy. Science 1990;247:294-301.
28. Brennan ML, Wu W, Fu X, et al. A tale of two controversies: defining both the role of peroxidases in nitrotyrosine formation in vivo using eosinophil peroxidase and myeloperoxidase-deficient mice, and the nature of peroxidase-generating reactive nitrogen species. J Biol Chem 2002;277:17415-27.
29. Quinlan T, BeruBe K, Hacker M, et al. Mechanisms of asbestos-induced nitric oxide production by rat alveolar macrophages in inhalation and in vitro models. Free Radic Biol Med 1998;24:778-88.
30. Punithavathi D, Venkatesan N, Babu M. Protective effects of curcumin against amiodarone-induced pulmonary fibrosis in rats. Br J Pharmacol 2003;139: 1342-50.
31. Churg A, Stevens B. Enhanced retention of asbestos fibers in the airways of human smokers. Am J Respir Crit Care Med 1995;151:1409-13.
32. Baldus S, Eiserich J, Brennan M, Jackson R, Alexander C, Freeman B. Spatial mapping of pulmonary and vascular nitrotyrosine reveals the pivotal role of myeloperoxidase as a catalyst for tyrosine nitration in inflammatory diseases. Free Radic Biol Med 2002;33: 1010-9.
33. Li J, Holbrook NJ. Common mechanisms for declines in oxidative stress tolerance and proliferation with aging. Free Radic Biol Med 2003;35:292-9.
34. Luczak K, Balcerczyk A, Soszynski M, Bartosz G. Low concentration of oxidant and nitric oxide donors stimulate proliferation of human endothelial cells in vitro. Cell Biol Int 2004;28:483-6.
35. Sesko A, Cabot M, Mossman B. Hydrolysis of inositol phospholipids precedes cellular proliferation in asbestos-stimulated tracheobronchial epithelial cells. Proc Natl Acad Sci U S A 1990;37:7385-9.
36. Van Der Vliet A, Nguyen MN, Shigenaga MK, Eiserich JP, Marelich GP, Cross CE. Myeloperoxidase and protein oxidation in cystic fibrosis. Am J Physiol Lung Cell Mol Physiol 2000;279:L537-46.
37. Quinlan T, BeruBe K, Marsh J, et al. Patterns of inflammation, cell proliferation, and related gene expression in lung after inhalation of chrysotile asbestos. Am J Pathol 1995;147:728-39.
38. Manning C, Cummins A, Jung M, et al. A mutant epidermal growth factor receptor targeted to lung epithelium inhibits asbestos-induced proliferation and proto-oncogene expression. Cancer Res 2002;62: 4169-75.
39. Buder-Hoffmann S, Palmer C, Vacek P, Taatjes D, Mossman B. Different accumulation of activated extracellular signal-regulated kinases (ERK 1/2) and role in cell-cycle alterations by epidermal growth factor, hydrogen peroxide, or asbestos in pulmonary epithelial cells. Am J Respir Cell Mol Biol 2001;24: 405-13.
40. Cummins A, Palmer C, Mossman B, Taatjes D. Persistent localization of activated extracellular signal-regulated kinases (ERK1/2) is epithelial cell-specific in an inhalation model of asbestosis. Am J Pathol 2003; 162:713-20.
41. Scapoli L, Ramos-Nino M, Martinelli M, Mossman B. Src-dependent ERK5 and Src/EGFR-dependent ERK1/2 activation is required for cell proliferation by asbestos. Oncogene 2004;23:805-13.
42. Zanella C, Timblin C, Cummins A, et al. Asbestos-induced phosphorylation of epidermal growth factor receptor is linked to c-fos expression and apoptosis. Am J Physiol Lung Cell Mol Physiol 1999;277:L684-93.
43. Ramos-Ninos M, Timblin C, Mossman B. Mesothelial cell transformation requires increased AP-1 binding activity and ERK-dependent Fra-1 expression. Cancer Res 2002;62:6065-9.
44. Midwinter R, Vissers M, Winterbourn C. Hypochlorous acid stimulation of the mitogen-activated protein kinase pathway enhances cell survival. Arch Biochem Biophys 2001;394:13-20.
45. Reddy S, Mossman B. Role and regulation of activator protein-1 in toxicant-induced responses of the lung. Am J Physiol Lung Cell Mol Physiol 2002;283:L1161-78.
46. Tamamori-Adachi M, Ito H, Sumrejkanchanakij P, et al. Critical role of cyclin D1 nuclear import in cardiomyocyte proliferation. Circ Res 2003;92:e12-9.
47. Burch PM, Yuan Z, Loonen A, Heintz NH. An extracellular signal-regulated kinase 1- and 2-dependent program of chromatin trafficking of c-Fos and Fra-1 is required for cyclin D1 expression during cell cycle reentry. Mol Cell Biol 2004;24:4696-709.