Anti-AIDS agents 65: Investigation of the in vitro oxidative metabolism of 3′,4′-di-O-(-)-camphanoyl-(+)-cis-khellactone derivatives as potent anti-HIV agents

Drug Metabolism and Disposition

Volumn 33, Issue 11, 2005, Pages 1588-1592

  Suzuki, Madoka ^a   Li, Yutai ^b,d   Smith, Philip C ^a   Swenberg, James A ^b   Martin, David E ^c   Morris Natschke, Susan L ^a   Lee, Kuo Hsiung ^a  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b IL   (United States)

^c Panacos Pharmaceuticals   (United States)

^d MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3',4' DI O CAMPHANOYLKHELLACTONE; 4 METHYLKHELLACTONE; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; DRUG METABOLITE; ESTER DERIVATIVE; KHELLACTONE; UNCLASSIFIED DRUG;

AEROBIC METABOLISM; ARTICLE; CONTROLLED STUDY; DRUG CLEARANCE; DRUG HALF LIFE; DRUG OXIDATION; DRUG POTENCY; DRUG STABILITY; DRUG STRUCTURE; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; ION TRAP MASS SPECTROMETRY; LIVER MICROSOME; PRIORITY JOURNAL; ULTRAVIOLET RADIATION;

ANTI-HIV AGENTS; CAMPHOR; HUMANS; LACTONES; MASS SPECTROMETRY; MICROSOMES, LIVER; OXIDATION-REDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP;

HUMAN IMMUNODEFICIENCY VIRUS;

EID: 27544451394     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.105.004218     Document Type: Article

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