Immunolocalization of estrogen receptor α and β in human fetal prostate

Journal of Urology

Volumn 174, Issue 5, 2005, Pages 2051-2053

  Shapiro, Ellen ^a   Huang, Hongying ^a   Masch, Rachel J ^a   McFadden, Deborah E ^b   Wilson, E Lynette ^a   Wu, Xue Ru ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CHILDREN S AND WOMEN S HEALTH CENTRE OF BRITISH COLUMBIA   (Canada)

Author keywords

Estrogen receptor alpha; Estrogen receptor beta; Fetus; Prostate

Indexed keywords

CYTOKERATIN 10; CYTOKERATIN 14; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA;

ARTICLE; CONTROLLED STUDY; EJACULATORY DUCT; EPITHELIUM; FETUS; HUMAN; HUMAN TISSUE; IMMUNOLOCALIZATION; MUELLERIAN DUCT; PREGNANCY; PRIORITY JOURNAL; PROSTATE; STAINING; TISSUE SECTION; UROGENITAL SYSTEM;

EID: 27544440550     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.ju.0000176472.90432.5b     Document Type: Article

References (20)

1. Prins, G. S.: Neonatal estrogen exposure induces lobe-specific alterations in adult rat prostate androgen receptor expression. Endocrinology, 130: 3703, 1992
2. Prins, G. S., Woodham, C., Lepinske, M. and Birch, L.: Effects of neonatal estrogen exposure on prostatic secretory genes and their correlation with androgen receptor expression in the separate prostate lobes of the adult rat. Endocrinology, 132: 2387, 1993
3. Prins, G. S. and Birch, L.: The developmental pattern of androgen receptor expression in rat prostate lobes is altered after neonatal exposure to estrogen. Endocinology, 136: 1303, 1995
4. Putz, O., Schwartz, C. B., LeBlanc, G. A., Cooper, R. L. and Prins, G. S.: Neonatal low- and high-dose exposure to estradiol benzoate in the male rat: II. Effects on male puberty and the reproductive tract. Biol Reprod, 65: 1506, 2001
5. Huang, L., Pu, Y., Alam, S., Birch, L. and Prins, G. S.: Estrogenic regulation of signaling pathways and homeobox genes during rat prostate development. J Androl, 25: 330, 2004
6. Jarred, R. A., Cancilla, B., Prins, G. S., Thayer, K. A., Cunha, G. R. and Risbridger, G. P.: Evidence that estrogens directly alter androgen-regulated prostate development. Endocrinology, 141: 3471, 2000
7. Risbridger, G., Wang, H., Young, P., Kurita, T., Wang, Y. Z., Lubahn, D. et al: Evidence that epithelial and mesenchymal estrogen receptor-alpha mediates effects of estrogen on prostatic epithelium. Dev Biol, 229: 432, 2001
8. Risbridger, G. P., Wang, H., Frydenberg, M. and Cunha, G.: The metaplastic effects of estrogen on mouse prostate epithelium: proliferation of cells with basal cell phenotype. Endocrinology, 142: 2443, 2001
9. Chang, W. Y. and Prins, G. S.: Estrogen receptor-beta: implications for the prostate gland. Prostate, 40: 115, 1999
10. Imamov, O., Morani, A., Shim, G. J., Omoto, Y., Thulin-Andersson, C., Warner, M. et al: Estrogen receptor beta regulates epithelial cellular differentiation in the mouse ventral prostate. Proc Natl Acad Sci USA, 101: 9375, 2004
11. Shapiro, E., Huang, H., McFadden, D. E., Masch, R. J., Ng, E., Lepor, H. et al: The prostatic utricle is not a mullerian duct remnant: immunohistochemical evidence for a distinct urogenital sinus origin. J Urol, 172: 1753, 2004
12. Zondek, T. and Zondek, L.: The fetal and neonatal prostate. In: Normal and Abnormal Growth of the Prostate. Edited by M. Goland. Springfield: C. C. Thomas, pp. 5-28, 1975
13. Huggins, C. and Hodges, C. V.: The effect of castration, of oestrogen and androgen injections on serum phosphatases in metastatic carcinoma of the prostate. Cancer Res, 1: 293, 1941
14. Rajfer, J. and Coffey, D. S.: Sex steroid imprinting of the immature prostate. Long-term effects. Invest Urol, 16: 186, 1978
15. Timms, B. G., Petersen, S. L. and vom Saal, F. S.: Prostate gland growth during development is stimulated in both male and female rat fetuses by intrauterine proximity to female fetuses. J Urol, 161: 1694, 1999
16. Adams, J. Y., Leav, I., Lau, K. M., Ho, S. M. and Pflueger, S. M.: Expression of estrogen receptor beta in the fetal, neonatal and prepubertal human prostate. Prostate, 52: 69, 2002
17. Wilson, J. D., Auchus, R. J., Leihy, M. W., Guryev, O. L., Estabrook, R. W., Osborn, S. M. et al: 5Alpha-androstane-3alpha,17beta-diol is formed in tammar wallaby pouch young testes by a pathway involving 5alpha-pregnane-3alpha, 17alpha-diol-20-one as a key intermediate. Endocrinology, 144: 575, 2003
18. Codesal, J., Regadera, J., Nistal, M., Regadera-Sejas, J. and Paniagua, R.: Involution of human fetal Leydig cells. An immunohistochemical, ultrastructural and quantitative study. J Anat, 172: 103, 1990
19. Couse, J. F. and Korach, K. S.: Estrogen receptor-alpha mediates the detrimental effects of neonatal diethylstilbestrol (DES) exposure in the murine reproductive tract. Toxicology, 205: 55, 2004
20. Horvath, L. G., Henshall, S. M., Lee, C. S., Head, D. R., Quinn, D. I., Makela, S. et al: Frequent loss of estrogen receptor-beta expression in prostate cancer. Cancer Res, 61: 5331, 2001