Regulated expression and function of the somatodendritic catecholamine neurotransmitter transporters

Journal of Pharmacological Sciences

Volumn 99, Issue 2, 2005, Pages 121-127

  Kitayama, Shigeo ^a   Sogawa, Chiharu ^a  

^a OKAYAMA UNIVERSITY   (Japan)

Author keywords

Chloride current; Dopamine; Norepinephrine; Reverse transport; Uptake inhibitor

Indexed keywords

AMPHETAMINE; CATECHOLAMINE DERIVATIVE; COCAINE; DOPAMINE TRANSPORTER; METHYLPHENIDATE; NEUROTRANSMITTER; NORADRENALIN TRANSPORTER;

ATTENTION DEFICIT DISORDER; BRAIN REGION; CATECHOLAMINE NERVE CELL; DENDRITIC CELL; DRUG MECHANISM; HUMAN; NERVE ENDING; NEUROTRANSMITTER RELEASE; PATHOGENESIS; POSITRON EMISSION TOMOGRAPHY; PROTEIN EXPRESSION; REVIEW; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; SOMATIC CELL;

EID: 27344459145     PISSN: 13478613     EISSN: 13478648     Source Type: Journal    
DOI: 10.1254/jphs.CPJ05003X     Document Type: Review

References (43)

1. Iversen LL. Role of transmitter uptake mechanisms in synaptic neurotransmission. Br J Pharmacol. 1971;41:571-591.
2. Amara SG, Kuhar MJ. Neurotransmitter transporters: recent progress. Ann Rev Neurosci. 1993;16:73-93.
3. Kitayama S, Dohi T. Cellular and molecular aspects of monoamine neurotransmitter transporters. Jpn J Pharmacol. 1996;72:195-208.
4. Giros B, Jaber M, Jones SR, Wightman RM, Caron MG. Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter. Nature. 1996;379:606-612.
5. Xu F, Gainetdinov RR, Wetsel WC, Jones SR, Bohn LM, Miller GW, et al. Mice lacking the norepinephrine transporter are supersensitive to psychostimulants. Nature Neurosci. 2000;3:465-471.
6. Ludwig M, Pittman QJ. Talking back:dendritic neurotransmitter release. Trends Neurosci. 2003;26:255-261.
7. Cragg SJ, Rice ME. DAncing past the DAT at a DA synapse. Trends Neurosci. 2004;27:270-277.
8. Bunney BS, Aghajanian GK, Roth RH. Comparison of effects of L-DOPA, amphetamine and apomorphine on firing rate of rat dopaminergic neurons. Nature. 1973;245:123-125.
9. Svensson TH, Usdin T. Feedback inhibition of brain noradrenaline neurons by tricyclic antidepressants: α-receptor mediation. Science. 1978;202:1089-1091.
10. Levi G, Raiteri M. Carrier-mediated release of neurotransmitters. Trends Neurosci. 1993;16:415-419.
11. Falkenburger BH, Barstow KL, Mintz IM. Dendrodendritic inhibition through reversal of dopamine transport. Science. 2001;293:2465-2470.
12. Sonders MS, Amara SG. Channels in transporters. Curr Opin Neurobiol. 1996;6:294-302.
13. Ingram SL, Prasad BM, Amara SG. Dopamine transporter-mediated conductances increase excitability of midbrain dopamine neurons. Nature Neurosci. 2002;5:971-978.
14. Carvelli L, McDonald PW, Blakely RD, DeFelice LJ. Dopamine transporters depolarize neurons by a channel mechanism. Proc Natl Acad Sci U S A. 2004;101:16046-16051.
15. Sulzer D, Galli A. Dopamine transport currents are promoted from curiosity to physiology. Trends Neurosci. 2003;26:173-176.
16. Chen NH, Reith MEA. Role of Axonal and somatodendritic monoamine transporters in action of uptake blockers. In: Reith MEA, editor. Neurotransmitter transporters: structure, function, and regulation. 1st ed. Totowa, NJ: Humana Press Inc; 1997. p. 345-391.
17. 3H]mazindol autoradiography. J Neurosci. 1985;5:1513-1521.
18. Galineau L, Kodas E, Guilloteau D, Vilar MP, Chalon S. Ontogeny of the dopamine and serotonin transporters in the rat brain: an autoradiographic study. Neurosci Lett. 2004;363:266-271.
19. Sanders JD, Happe HK, Bylund DB, Murrin LC. Development of the norepinephrine transporter in the rat CNS. Neuroscience. 2005;130:107-117.
20. Gu HH, Ahn J, Caplan MJ, Blakely RD, Levey AI, Rudnick G. Cell-specific sorting of biogenic amine transporters expressed in epithelial cells. J Biol Chem. 1996;271:18100-18106.
21. Gu HH, Wu X, Giros B, Caron MG, Caplan MJ, Rudnick G. The NH2-terminus of norepinephrine transporter contains a basolateral localization signal for epithelial cells. Mol Biol Cell. 2001;12:3797-3807.
22. Torres G, Yao WD, Mohn AR, Quan H, Kim KM, Levey AI, et al. Functional interaction between monoamine plasma membrane transporters and the synaptic PDZ domain-containing protein PICK1. Neuron. 2001;30:121-134.
23. Kimmel HL, Carroll FI, Kuhar MJ. Dopamine transporter synthesis and degradation rate in rat striatum and nucleus accumbens using RTI-76. Neuropharmacology. 2000;39:578-585.
24. Daniels GM, Amara SG. Regulated trafficking of the human dopamine transporter. Clathrin-mediated internalization and lysosomal degradation in response to phorbol esters. J Biol Chem. 1999;274:35794-35801.
25. Melikian, Buckley KM. Membrane trafficking regulates the activity of the human dopamine transporter. J Neurosci. 1999;15:7699-7710.
26. Holton KL, Loder MK, Melikian HE. Nonclassical, distinct endocytic signals dictate constitutive and PKC-regulated neurotransmitter transporter internalization. Natue Neurosci. 2005;7:881-888.
27. Shomig A, Kurz T, Richardt G, Schomig E. Neuronal sodium homeostasis and axoplasmic amine concentration determine calcium-independent noradrenaline release in normoxic and ischemic rat heart. Circ Res. 1988;63:214-226.
28. Fischer JF, Cho AK. Chemical release of dopamine from striatal homogenates: evidence for an exchange diffusion model. J Pharmacol Exp Ther. 1979;208:203-209.
29. Sitte HH, Hiptmair B, Zwach J, Pifl C, Singer EA, Scholze P. Quantitative analysis of inward and outward transport rates in cells stably expressing the cloned human serotonin transporter: inconsistencies with the hypothesis of facilitated exchange diffusion. Mol Pharmacol. 2001;59:1129-1137.
30. Siedel S, Singer EA, Just H, Farhan H, Scholze P, Kudlacek O, et al. Amphetamines take two to tango: an oligomer-based counter-transport model of neurotransmitter transport explores the amphetamine action. Mol Pharmacol. 2005;67:140-151.
31. Khoshbouei H, Sen N, Guptaroy B, Johnson L, Lund D, Gnegy ME, et al. N-terminal phosphorylation of the dopamine transporter is required for amphetamine-induced efflux. PLoS Biol. 2004;2:387-393.
32. Blakely RD. Dopamine's reversal of fortune. Science. 2001;293:2407-2409.
33. Nirenberg MJ, Vaughan RA, Uhl GR, Kuhar MJ, Pickel VM. The dopamine transporter is localized to dendritic and axonal plasma membranes of nigrostriatal dopaminergic neurons. J Neurosci. 1996;16:436-447.
34. Nirenberg MJ, Chan J, Liu Y, Edwards RH, Pickel VM. Ultrastructural localization of the vesicular monoamine transporter-2 in midbrain dopaminergic neurons: potential sites for somatodendritic storage and release of dopamine. J Neurosci. 1996;16:4135-4145.
35. Nirenberg MJ, Chan J, Vaughan RA, Uhl GR, Kuhar MJ, Pickel VM. Immunogold localization of the dopamine transporter: an ultrastructural study of the rat ventral tegmental area. J Neurosci. 1997;17:5255-5262.
36. Stite N, Trendelenburg U. The outward transport of axoplasmic noradrenaline induced by a rise of the sodium concentration in the adrenergic nerve endings of the rat vas deferens. Naunyn Schmiedebergs Arch Pharmacol. 1984;327:124-132.
37. Floresco SB, West AR, Ash B, Moore H, Grace AA. Afferent modulation of dopamine neuron firing differentially regulates tonic and phasic dopamine transmission. Nature Neurosci. 2003;6:968-973.
38. Payne JA, Rivera C, Voipio J, Kaila K. Cation-chloride co-transporters in neuronal communication, development and trauma. Trends Neurosci. 2003;26:199-206.
39. Ben-Ari Y. Excitatory actions of GABA during development: the nature of the nurture. Nature Rev Neurosci. 2002;3:728-739.
40. Gulacsi A, Lee CR, Sik A, Viitanen T, Kaila K, Tepper JM, et al. Cell type-specific differences in chloride-regulatory mechanisms and GABAA receptor-mediated inhibition in rat substantia nigra. J Neurosci. 2003;23:8237-8246.
41. Sagvolden T, Sergeant JA. Attention deficit/hyperactivity disorder-from brain dysfunctions to behaviour. Behav Brain Res. 1998;94:1-10.
42. Seeman P, Madras B. Methylphenidate elevates resting dopamine which lowers the impulse-triggered release of dopamine: a hypothesis. Behav Brain Res. 2002;130:79-83.
43. Jucaite A, Fernell E, Halldin C, Forssberg H, Farde L. Reduced midbrain dopamine transporter binding in male adolescents with attention-deficit/ hyperactivity disorder: association between striatal dopamine markers and motor hyperactivity. Biol Psychiatry. 2005;57:229-238.