Systemic inflammatory markers in acute coronary syndrome: Association with cardiovascular risk factors and effect of early lipid lowering

Coronary Artery Disease

Volumn 16, Issue 7, 2005, Pages 415-422

  Meredith, Ian T ^a   Plunkett, Julie C ^a   Worthley, Stephen G ^a   Hope, Sarah A ^a   Cameron, James D ^a  

^a MONASH MEDICAL CENTRE   (Australia)

Author keywords

Acute coronary syndrome; Early treatment; Inflammatory marker; Statin therapy

Indexed keywords

BIOLOGICAL MARKER; C REACTIVE PROTEIN; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 6; PLACEBO; PRAVASTATIN; VASCULAR CELL ADHESION MOLECULE 1;

ACUTE HEART INFARCTION; ADULT; AGED; ANGINA PECTORIS; ARTICLE; CARDIOVASCULAR RISK; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFECT; FEMALE; HUMAN; HYPERTENSION; INFLAMMATION; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RANDOMIZED CONTROLLED TRIAL; SEX DIFFERENCE; SMOKING; TREATMENT OUTCOME;

AGED; ANGINA, UNSTABLE; BIOLOGICAL MARKERS; DOUBLE-BLIND METHOD; FEMALE; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; INFLAMMATION; LOGISTIC MODELS; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; PRAVASTATIN; RISK FACTORS;

EID: 27344448150     PISSN: 09546928     EISSN: None     Source Type: Journal    
DOI: 10.1097/00019501-200510000-00001     Document Type: Article

References (47)

1. Den Hartog FR, Van Kalmthout PM, Van Loenhout TT, Schaafsma HJ, Rila H, Verheugt FW. Pravastatin in acute ischaemic syndromes: results of a randomised placebo-controlled Trial. Int J Clin Pract 2001; 55:3000-3004.
2. Sposito AC, Chapman MJ. Statin therapy in acute coronary syndromes mechanistic insight into clinical benefit. Arterioscler Thromb Vasc Biol 2002; 22:1524-1534.
3. Ross R. Atherosclerosis - an inflammatory disease [see comments]. N Engl J Med 1999; 340:115-126.
4. Rifai N, Ridker PM. High-sensitivity C-reactive protein: a novel and promising marker of coronary heart disease. Clin Chem 2001; 47:403-411.
5. Ridker PM, Hennekens CH, Buring JE, Rifai N. C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women. N Engl J Med 2000; 342:836-843.
6. Bermudez EA, Rafai N, Buring J, Manson JE, Ridker PM. Interrelationships among circulating interleukin-6, C-reactive protein, and traditional cardiovascular risk factors in women. Arteriosder Thromb Vasc Biol 2002; 22:1668-1673.
7. Ridker PM, Cushman M, Stampfer MJ, Tracy RP, Hennekens CH. Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men. N Engl J Med 1997; 336:973-979.
8. Ridker PM, Rifai N, Pfeffer MA, Sacks F, Braunwald E. Long-term effects of pravastatin on plasma concentration of C-reactive protein. Circulation 1999; 100:230-235.
9. Thompson PL. Clinical relevance of statins: instituting treatment early in acute coronary syndrome patients. Atheroscler Suppl 2001; 2:15-19.
10. Thompson PL, Meredith IT, Amerena J, Campbell TJ, Sloman TJ, Harris PJ, For the PACT Investigators. Effect of pravastatin compared with placebo initiated within 24 hours of the onset of acute myocardial infarction or unstable angina; the pravastatin acute cononary treatment (PACT) trial. Am Heart J 2004; 148:e2.
11. Hwang SJ, Ballantyne CM, Sharrett AR, Smith LC, Davis CE, Gotto AM, Jr. et al. Circulating adhesion molecules VCAM-1, ICAM-1, and E-selectin in carotid atherosclerosis and incident coronary heart disease cases: the Atherosclerosis Risk In Communities (ARIC) study. Circulation 1997; 96:4219-4225.
12. Malik I, Danesh J, Whincup P, Bhatia V, Papacosta O, Walker M, et al. Soluble adhesion molecules and prediction of coronary heart disease: a prospective study and meta-analysis. Lancet 2001; 358:971-976.
13. O'Malley T, Ludlam CA, Riemermsa RA, Fox KA. Early increase in levels of soluble inter-cellular adhesion molecule-1 (sICAM-1); potential risk factor for the acute coronary syndromes. Eur Heart J 2001; 22:1226-1234.
14. Rohde LE, Hennekens CH, Ridker PM. Cross-sectional study of soluble intercellular adhesion molecule-1 and cardiovascular risk factors in apparently healthy men. Arterioscler Thromb Vasc Biol 1999; 19:1595-1599.
15. Ridker PM, Hennekens CH, Roitman-Johnson B, Stampfer MJ, Allen J. Plasma concentration of soluble intercellular adhesion molecule 1 and risks of future myocardial infarction in apparently healthy men [see comments], Lancet 1998; 351:88-92.
16. Tomoda H, Aoki N. Plasma soluble P-selectin in acute myocardial infarction: effects of coronary recanalization therapy. Angiology 1998; 49:807-813.
17. Shimomura H, Ogawa H, Arai H, Moriyama Y, Takazoe K, Hirai N, et al. Serial changes in plasma levels of soluble P-selectin in patients with acute myocardial infarction. Am J Cardiol 1998; 81:397-400.
18. Mulvihill N, Foley JB, Ghaisas N, Murphy R, Crean P, Walsh M. Early temporal expression of soluble cellular adhesion molecules in patients with unstable angina and subendocardial myocardial infarction. Am J Cardiol 1999; 83:1265-1267.
19. Ogawa H, Yasue H, Miyao Y, Sakamoto T, Soejima H, Nishiyama K, et al. Plasma soluble intercellular adhesion molecule-1 levels in coronary circulation in patients with unstable angina. Am J Cardiol 1999; 83:38-42.
20. Miwa K, Igawa A, Inoue H. Soluble E-selectin, ICAM-1 and VCAM-1 levels in systemic and coronary circulation in patients with variant angina [see comments]. Cardiovasc Res 1997; 36:37-44.
21. Gurbel PA, Serebruany VL. Soluble vascular cell adhesion molecule-1 and E-selectin in patients with acute myocardial infarction treated with thrombolytic agents. Am J Cardiol 1998; 81:772-775.
22. Ghaisas NK, Shahi CN, Foley B, Goggins M, Crean P, Kelly A, et al. Elevated levels of circulating soluble adhesion molecules in peripheral blood of patients with unstable angina. Am J Cardiol 1997; 80:617-619.
23. Li YH, Teng JK, Tsai WC, Tsai LM, Lin LJ, Chen JH. Elevation of soluble adhesion molecules is associated with the severity of myocardial damage in acute myocardial infarction. Am J Cardiol 1997; 80:1218-1221.
24. Shyu KG, Chang H, Lin CC, Kuan P. Circulating intercellular adhesion molecule-1 and E-selectin in patients with acute coronary syndrome. Chest 1996; 109:1627-1630.
25. Suefuji H, Ogawa H, Yasue H, Sakamoto T, Miyao Y, Kaikita K, et al. Increased plasma level of soluble E-selectin in acute myocardial infarction. Am Heart J 2000; 140:243-248.
26. Ikeda H, Takajo Y, Ichiki K, Ueno T, Maki S, Noda T, et al. Increased soluble form of P-selectin in patients with unstable angina. Circulation 1995; 92:1693-1696.
27. Mulvihill NT, Foley JB, Murphy RT, Curtin R, Crean PA, Walsh M. Risk stratification in unstable angina and non-Q wave myocardial infarction using soluble cell adhesion molecules. Heart 2001; 85:623-627.
28. Parker C, III, Vita JA, Freedman JE. Soluble adhesion molecules and unstable coronary artery disease. Atherosclerosis 2001; 156:417-424.
29. Porsch-Oezcueruemez M, Kunz D, Kloer HU, Luley C. Evaluation of serum levels of solubilized adhesion molecules and cytokine receptors in coronary heart disease. J Am Coll Cardiol 1999; 34:1995-2001.
30. Abe Y, El-Masri B, Kimball KT, Pownall H, Reilly CF, Osmundsen K et al. Soluble cell adhesion molecules in hypertriglyceridemia and potential significance on monocyte adhesion. Arterioscler Thromb Vasc Biol 1998; 18:723-731.
31. Blankenberg S, Rupprecht HJ, Bickel C, Peetz D, Hafner G, Tiret L, et al. Circulating cell adhesion molecules and death in patients with coronary artery disease. Circulation. 2001; 104:1336-1342.
32. De Caterina R, Ghiadoni L, Taddei S, Virdis A, Almerigogna F, Basta G, et al. Soluble E-selectin in essential hypertension: a correlate of vascular structural changes. Am J Hypertens 2001; 14:259-266.
33. Johnson RC, Chapman SM, Dong ZM, Ordovas JM, Mayadas TN, Herz J, et al. Absence of P-selectin delays fatty streak formation in mice. J Clin Invest 1997; 99:1037-1043.
34. Tsao PS, Buitrago R, Chan JR, Cooke JP. Fluid flow inhibits endothelial adhesiveness. Nitric oxide and transcriptional regulation of VCAM-1. Circulation 1996; 94:1682-1689.
35. Chen NG, Holmes M, Reaven GM. Relationship between insulin resistance, soluble adhesion molecules, and mononuclear cell binding in healthy volunteers. J Clin Endocrinol Metab 1999; 84:3485-3489.
36. Cominacini L, Fratta Pasini A, Garbin U, Campagnola M, Davoli A, Rigoni A, et al. E-selectin plasma concentration is influenced by glycaemic control in NIDDM patients: possible role of oxidative stress. Diabetologia 1997; 40:584-589.
37. Scalia R, Appel Z Jr, Lefer AM. Leukocyte-endothelium interaction during the early stages of hypercholesterolemia in the rabbit: role of P-selectin, ICAM-1, and VCAM-1. Arterioscler Thromb Vasc Biol 1998; 18:1093-1100.
38. Smalley DM, Lin JH, Curtis ML, Kobari Y, Stemerman MB, Pritchard KA, Jr. Native LDL increases endothelial cell adhesiveness by inducing intercellular adhesion molecule-1. Arterioscler Thromb Vasc Biol 1996; 16:585-590.
39. Zhu Y, Liao HL, Lin JH, Verna L, Stemerman MB. Low-density lipoprotein augments interleukin-1-induced vascular adhesion molecule expression in human endothelial cells. Atherosclerosis 1999; 144:357-365.
40. Cockerill GW, Rye KA, Gamble JR, Vadas MA, Barter PJ. High-density lipoproteins inhibit cytokine-induced expression of endothelial call adhesion molecules. Arterioscler Thromb Vasc Biol 1995; 15:1987-1994.
41. Sardo MA, Castaldo M, Cinquegrani M, Bonaiuto M, Maesano A, Schepis F, et al. Effects of simvastatin treatment on sICAM-1 and sE-selectin levels in hypercholesterolemic subjects. Atherosclerosis 2001; 155:143-147.
42. Rauch U, Osende JI, Chesebro JH, Fuster V, Vorchheimer DA, Harris K, et al. Statins and cardiovascular diseases: the multiple effects of lipid-lowering therapy by statins. Atherosclerosis 2000; 153:181-189.
43. Murphy RT, Foley JB, Mulvihill N, Crean P, Walsh MJ. Impact of preexisting statin use on adhesion molecule expression in patients presenting with acute coronary syndromes. Am J Cardiol 2001; 87:446-448.
44. Solheim S, Seljeflot I, Arnesen H, Eritsland J, Eikvar L. Reduced levels of TNF alpha in hypercholesterolemic individuals after treatment with pravastatin for 8 weeks. Atherosclerosis 2001; 157:411-415.
45. Sbarouni E, Kroupis C, Kyriakides ZS, Koniavitou K, Kremastinos DT. Cell adhesion molecules in relation to simvastatin and hormone replacement therapy in coronary artery disease. Eur Heart J 2000; 21:975-980.
46. Koh KK, Cardillo C, Bui MN, Hathaway L, Csako G, Waclawiw MA, et al. Vascular effects of estrogen and cholesterol-lowering therapies in hypercholesterolemic postmenopausal women. Circulation 1999; 99:354-360.
47. Ridker PM, Cannon CP, Morrow D, Rifal N, Rose LM, McCabe CH, et al. C-reactive protein levels and outcomes after statin therapy. N Engl J Med 2005; 352:20-28.