Puerariae radix prevents bone loss in castrated male mice

Metabolism: Clinical and Experimental

Volumn 54, Issue 11, 2005, Pages 1536-1541

  Wang, Xinxiang ^a   Wu, Jian ^a   Chiba, Hiroshige ^a   Yamada, Kazuhiko ^a   Ishimi, Yoshiko ^a  

^a NATIONAL INSTITUTE OF HEALTH AND NUTRITION   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN; ESTRADIOL; PLANT EXTRACT; PUERARIAE RADIX EXTRACT; UNCLASSIFIED DRUG;

ANDROGEN DEFICIENCY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE DENSITY; CASTRATION; CHINESE HERB; CONTROLLED STUDY; DIET SUPPLEMENTATION; DIETARY INTAKE; DOSE RESPONSE; DRUG EFFECT; DRUG MEGADOSE; DRUG POTENCY; FEMUR; LOW DRUG DOSE; MALE; METAPHYSIS; MORPHOMETRICS; MOUSE; NONHUMAN; ORCHIECTOMY; ORGAN WEIGHT; OSTEOLYSIS; OSTEOPOROSIS; PRIORITY JOURNAL; PROPHYLAXIS; PUERARIA; SEMINAL VESICLE; TRABECULAR BONE; VOLUMETRY;

AGING; ANIMALS; ANIMALS, OUTBRED STRAINS; BODY WEIGHT; DRUGS, CHINESE HERBAL; HYPOGONADISM; MALE; MICE; ORCHIECTOMY; ORGAN SIZE; OSTEOPOROSIS; PUERARIA; SEMINAL VESICLES;

EID: 27344441175     PISSN: 00260495     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.metabol.2005.05.022     Document Type: Article

References (34)

1. H. Adlercreutz, E. Hamalainen, S. Gorbach, and B. Goldin Dietary phyto-oestrogens and the menopause in Japan Lancet 339 1992 1233
2. T.V. Nguyan, J.A. Eisman, P.J. Kelly, and P.N. Sambrook Risk factors for osteoporotic fractures in elderly men Am J Epidemiol 144 1996 255 263
3. E.S. Orwoll, and R.F. Klein Osteoporosis in men Endocr Rev 16 1995 87 116
4. S. Khosla, L.J. Melton III, E.J. Atkinson, W.M. O'Fallon, G.G. Klee, and B.L. Riggs Relationship of serum sex steroid levels and bone turnover markers with bone mineral density in men and women: a key role for bioavailable estrogen J Clin Endocrinol Metab 83 1998 2266 2274
5. C.W. Slemenda, C. Longcope, L. Zhou, S.L. Hui, M. Peacock, and C.C. Johnston Sex steroids and bone mass in older men. Positive associations with serum estrogens and negative associations with androgens J Clin Invest 100 1997 1755 1759
6. A. Falahati-Nini, B.L. Riggs, E.J. Atkinson, W.M. O'Fallon, R. Eastell, and S. Khosla Relative contributions of testosterone and estrogen in regulating bone resorption and formation in normal elderly men J Clin Invest 106 2000 1553 1560
7. M.L. Brandi Natural and synthetic isoflavones in the prevention and treatment of chronic diseases Calcif Tissue Int 61 1997 S5 S8
8. S. Barnes Evolution of the health benefits of soy isoflavones Proc Soc Exp Biol Med 217 1998 386 392
9. H. Wiseman The therapeutic potential of phytoestrogens Expert Opin Investig Drugs 9 2000 1829 1840
10. H. Adlercreutz, H. Markkanen, and S. Watanabe Plasma concentrations of phyto-oestrogens in Japanese men Lancet 342 1993 1209 1210
11. M. Messina, V. Persky, K.D.R. Setchell, and S. Barnes Soy intake and cancer risk: a review of in vitro and in vivo data Nutr Cancer 21 1994 113 131
12. H. Wei, R. Bowen, Q. Cai, S. Barnes, and Y. Wang Antioxidant and antipromotional effects of the soybean isoflavone genistein Proc Soc Exp Biol Med 208 1995 124 130
13. B.H. Arjmandi, M.J. Getlinger, N.V. Goyal, C.M. Hasler, S. Juma, and M.L. Drum Role of soy protein with normal or reduced isoflavone content in reversing bone loss induced by ovarian deficiency in rats Am J Clin Nutr 68 1998 S1858 S1863
14. C.R. Draper, M.J. Edel, I.M. Dick, A.G. Randall, G.B. Martin, and R.L. Prince Phytoestrogens reduce bone loss and bone resorption in oophorectomized rats J Nutr 127 1997 1795 1799
15. S.M. Potter, J.A. Baum, H. Teng, R.J. Stillman, N.F. Shay, and J.W. Erdman Soy protein and isoflavones: their effects on blood lipids and bone density in postmenopausal women Am J Clin Nutr 68 1998 S1375 S1379
16. Y. Ishimi, C. Miyaura, M. Ohmura, Y. Onoe, T. Sato, and Y. Uchiyama Selective effects of genistein, a soybean isoflavone, on B-lymphopoiesis and bone loss caused by estrogen deficiency Endocrinology 140 1999 1893 1900
17. Y. Ishimi, N. Arai, X. Wang, J. Wu, K. Umegaki, and C. Miyaura Difference in effective dosage of genistein on bone and uterus in ovariectomized mice Biochem Biophys Res Commun 274 2000 697 701
18. J. Wu, X. Wang, M. Takasaki, A. Ohta, M. Higuchi, and Y. Ishimi Cooperative effects of exercise training and genistein administration on bone mass in ovariectomized mice J Bone Miner Res 16 2001 1829 1836
19. Y. Ishimi, M. Yoshida, S. Wakimoto, J. Wu, H. Chiba, and X. Wang Genistein, a soybean isoflavone, affects bone marrow lymphopoiesis and prevents bone loss in castrated male mice Bone 31 2002 180 185
20. J. Wu, X. Wang, H. Chiba, M. Higuchi, M. Takasaki, and A. Ohta Combined intervention of exercise and genistein prevented androgen deficiency-induced bone loss in mice J Appl Physiol 94 2003 335 342
21. J. Wu, X. Wang, M. Higuchi, K. Yamada, and Y. Ishimi High bone mass gained by exercise in growing male mice is increased by subsequent reduced exercise J Appl Physiol 97 2004 806 810
22. J. Wu, X. Wang, H. Chiba, M. Higuchi, T. Nakatani, and O. Ezaki Combined intervention of soy isoflavone and moderate exercise prevents body fat elevation and bone loss in ovariectomized mice Metabolism 53 2004 942 948
23. L.L. Fan, D.D. O'Keefe, and W.WJ. Powell Pharmacologic studies on radix puerariae: effect of puerarin on regional myocardial blood flow and cardiac hemodynamics in dogs with acute myocardial ischemia Chin Med J 98 1985 821 832
24. X. Wang, J. Wu, H. Chiba, K. Umegaki, K. Yamada, and Y. Ishimi Puerariae radix prevents bone loss in ovariectomized mice J Bone Miner Metab 21 2003 268 275
25. N. Gaumet-Meunier, V. Coxam, S. Robins, P. Pastoureau, A. Pointillart, and M.J. Davicco Gonadal steroids and bone metabolism in young castrated male rats Calcif Tissue Int 66 2000 470 475
26. Y. Onoe, C. Miyaura, M. Ito, H. Ohta, S. Nozawa, and T. Suda Comparative effects of estrogen and raloxifene on B lymphopoiesis and bone loss induced by sex steroid deficiency in mice J Bone Miner Res 15 2000 541 549
27. R.G. Erben, J. Eberle, K. Stahr, and M. Goldberg Androgen deficiency induces high turnover osteopenia in aged male rats: a sequential histomorphometric study J Bone Miner Res 15 2000 1085 1098
28. C. Miyaura, K. Toda, M. Inada, T. Ohshiba, C. Matusmoto, and T. Okada Sex- and age-related response to aromatase deficiency in bone Biochem Biophys Res Commun 280 2001 1062 1068
29. E.P. Smith, J. Body, G.R. Frank, H. Takahashi, R.M. Cohen, and B. Specker Estrogen resistance caused by a mutation in the estrogen-receptor gene in a man N Engl J Med 331 1994 1056 1061
30. C. Carani, K. Qin, M. Simoni, M. Faustini-fustini, S. Serpente, and J. Body Effect of testosterone and estradiol in a man with aromatase deficiency N Engl J Med 337 1997 91 95
31. A. Morishima, M.M. Grumbach, E.R. Simpson, C. Fisher, and K. Qin Aromatase deficiency in male and female siblings caused by a novel mutation and the physiological role of estrogens J Clin Endocrinol Metab 80 1995 3689 3698
32. T. Toda, T. Uesugi, K. Hirai, H. Nukaya, K. Tsuji, and H. Ishida New 6-O-acyl isoflavone glycosides from soybeans fermented with Bacillus subtilis (natto). I. 6-O-Succinylated isoflavone glycosides and their preventive effects on bone loss in ovariectomized rats fed a calcium-deficient diet Biol Pharm Bull 22 1999 1193 1201
33. A. Ohta, M. Uehara, K. Sakai, M. Takasaki, H. Adlercreutz, and T. Morohashi A combination of dietary fructooligosaccharides and isoflavone conjugates increases femoral bone mineral density and equol production in ovariectomized mice J Nutr 132 2002 2048 2054
34. G.G. Kuiper, J.G. Lemmen, B. Carlsson, J.C. Corton, S.H. Safe, and P.T. van der Saag Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor beta Endocrinology 139 1998 4252 4263