Brain activation of spider phobics towards disorder-relevant, generally disgust- and fear-inducing pictures

Neuroscience Letters

Volumn 388, Issue 1, 2005, Pages 1-6

  Schienle, Anne ^a,b   Schäfer, Axel ^a   Walter, Bertram ^a   Stark, Rudolf ^a   Vaitl, Dieter ^a  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

^b UNIVERSITY OF TRIER   (Germany)

Author keywords

Disgust; Fear; FMRI; Spider phobia; Visual stimuli

Indexed keywords

ADULT; AMYGDALOID NUCLEUS; ARTICLE; ASSOCIATION CORTEX; CLINICAL ARTICLE; CONTROLLED STUDY; FEAR; FEMALE; HIPPOCAMPUS; HUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PHOBIA; PREFRONTAL CORTEX; PRIORITY JOURNAL; SPIDER; VISUAL STIMULATION; ANIMAL; BRAIN; BRAIN MAPPING; HEMISPHERIC DOMINANCE; NERVE TRACT; PATHOPHYSIOLOGY; PHOTOSTIMULATION; PHYSIOLOGY; SEX DIFFERENCE;

ADULT; AMYGDALA; ANIMALS; BRAIN; BRAIN MAPPING; FEAR; FEMALE; FUNCTIONAL LATERALITY; HIPPOCAMPUS; HUMANS; MAGNETIC RESONANCE IMAGING; NEURAL PATHWAYS; PHOBIC DISORDERS; PHOTIC STIMULATION; PREFRONTAL CORTEX; SEX FACTORS; SPIDERS;

EID: 27244451938     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2005.06.025     Document Type: Article

References (25)

1. American Psychiatric Association (APA), Diagnostic and Statistical Manual of Mental Disorders, fourth edition, American Psychiatric Press, Washington, DC, 1994.
2. P.J. DeJong, H. Merckelbach, Blood-injection-injury phobia and fear of spiders: domain specific individual differences in disgust sensitivity, Pers. Ind. Diff. 24 (1998) 153-158.
3. S. Dilger, T. Straube, H.J. Mentzel, C. Fitzek, J. Reichenbach, H. Hecht, S. Krieschel, I. Gutberlet, W. Miltner, Brain activation to phobia-related pictures in spider phobic humans: an event-related functional magnetic resonance imaging study, Neurosci. Lett. 248 (2003) 29-32.
4. W.C. Drevets, H. Burton, T.O. Videen, A.Z. Snyder, J.R. Simpson, M.E. Raichle, Blood flow changes in human somatosensory cortex during anticipated stimulation, Nature 373 (1995) 249-252.
5. M. Fredrikson, P. Annas, H. Fischer, G. Wik, Gender and age differences in the prevalence of specific fears and phobias, Behav. Res. Ther. 34 (1996) 33-39.
6. M. Fredrikson, G. Wik, P. Annas, K. Ericson, S. Stone-Elander, Functional neuroanatomy of visually elicited simple phobic fear: Additional data and theoretical analysis, Psychophysiology 32 (1995) 43-48.
7. A. Johanson, L. Gustafson, U. Passant, J. Risberg, G. Smith, S. Warkentin, D. Tucker, Brain function in spider phobia, Psychiatr. Res: Neuroimaging 84 (1998) 101-111.
8. R. Klorman, T. Weerts, J. Hastings, B. Melamed, P. Lang, Psychometric description of some fear-specific questionnaires, Behav. Res. 5 (1974) 401-409.
9. P.J. Lang, M. Bradly, B. Cuthbert, International Affective Picture System, Gainsville, Center for Research in Psychophysiology, University of Florida, 1995.
10. L. Laux, P. Glanzmann, P. Schaffner, C.D. Spielberger, Das State-Trait-Angstinventar, Beltz, Weinhem, 1981.
11. J. Margraf, Diagnostisches Kurz-Interview bei psychischen Störungen (Mini DIPS), Springer-Verlag, Berlin, 1994.
12. S.A.N. Mulkens, P.J. DeJong, H. Merckelbach, Disgust and spider phobia, J. Abnorm. Psych. 105 (1996) 464-468.
13. V. Paquette, J. Lévesque, B. Mensour, J.-M. Leroux, G. Beaudoin, P. Bourgouin, M. Beauregard, Change the mind and you change the brain: effects of cognitive behavioral therapy on the neural correlates of spider phobia, NeuroImage 18 (2003) 401-409.
14. K.L. Phan, T. Wager, S.F. Taylor, I. Liberzon, Functional neuroanatomy of emotion: a meta-analysis of emotion activation studies in PET and fMRI, NeuroImage 16 (2002) 331-348.
15. S.L. Rauch, C.R. Savage, N.M. Alpert, E.C. Miguel, L. Baer, H.C. Breiter, A positron emission tomography study of simple phobic symptom provocation, Arch. Gen. Psychiat. 52 (1995) 20-28.
16. E.T. Rolls, The Brain and Emotion, University Press, Oxford, 1999.
17. D. Sabatinelli, T. Flaisch, M.M. Bradley, J.R. Fitzsimmons, P.J. Lang, Affective picture perception: gender differences in visual cortex, NeuroReport 15 (2004) 1109-1112.
18. A. Schienle, A. Schäfer, R. Stark, B. Walter, D. Vaitl, The relationship between disgust sensitivity, trait anxiety and brain activity during disgust induction, Neuropsychobiology 51 (2005) 86-92.
19. A. Schienle, B. Walter, R. Stark, D. Vaitl, Ein Fragebogen zur Erfassung der Ekelempfindlichkeit [A questionnaire for the assessment of disgust sensitivity], Zeitschrift für Klinische Psychologie und Psychotherapie 31 (2002) 110-120.
20. D.F. Tolin, J.M. Lohr, C.N. Sawchuck, T.C. Lee, Disgust and disgust sensitivity in blood-injection-injury and spider phobia, Behav. Res. Ther. 35 (1997) 949-953.
21. N. Tzourio-Mazoyer, B. Landeau, D. Papathanassiou, F. Crivello, O. Etard, N. Delcroix, Automated anatomical labeling of activations in SPM using a macroscopic anatomical parcellation of the MNI MRI single-subject brain, NeuroImage 15 (2002) 273-289.
22. B. Walter, C. Blecker, P. Kirsch, G. Sammer, A. Schienle, R. Stark R, MARINA: an easy to use tool for the creation of MAsks for Region of INterest Analyses, NeuroImage 19 (2003) CD-ROM.
23. G. Wik, M. Fredrikson, K. Ericson, L. Ericson, S. Stone-Elander, T. Greitz, A functional cerebral response to frightening visual stimulation, Psychiatry Res. 50 (1993) 15-24.
24. K.J. Worsley, S. Marrett, P. Neelin, A.C. Vandal, K.J. Friston, A. Evans, A unified statistical approach for determining significant voxels in images of cerebral activation, Hum. Brain Map. 4 (1996) 58-73.
25. D.H. Zald, The human amygdala and the emotional evaluation of sensory stimuli, Brain Res. Rev. 41 (2003) 88-123.