Structure elucidation and antioxidant activity of (-)-isosilandrin isolated from silybum marianum L.

Chemistry and Biodiversity

Volumn 1, Issue 11, 2004, Pages 1668-1677

  Samu, Zsuzsanna ^a   Nyiredy, Szabolcs ^a   Baitz Gacs, Eszter ^b   Varga, Zsuzsa ^c   Kurtan, Tibor ^c   Dinya, Zoltan ^c   Antus, Sandor ^c  

^a Research Institute for Medicinal Plants   (United States)

^b CTRL RES INSTITUTE FOR CHEMISTRY   (Hungary)

^c UNIVERSITY OF DEBRECEN   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; DRUG DERIVATIVE; ISOSILYBIN; PLANT EXTRACT; SILYMARIN;

ARTICLE; CHEMISTRY; DRUG EFFECT; FRUIT; HUMAN; ISOLATION AND PURIFICATION; LEUKOCYTE; METABOLISM; SILYBUM MARIANUM; STRUCTURE ACTIVITY RELATION;

ANTIOXIDANTS; FRUIT; HUMANS; LEUKOCYTES; MILK THISTLE; PLANT EXTRACTS; SILYMARIN; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 27144559120     PISSN: 16121872     EISSN: 16121880     Source Type: Journal    
DOI: 10.1002/cbdv.200490125     Document Type: Article

References (40)

1. H.Wagner, in 'Plant Constituents with Antihepatotoxic Activity in Natural Products as Medicinal Agents, Ed. J. L. Beal, E. Reinhard, Hippokrates Verlag, Stuttgart, 1980, p. 217-238
2. G. Buzelli, S. Moscarella, A. Giusti, A. Duchini, C. Marena, M. Lampertico, Int. J. Clin. Pharmacol. Ther. Toxicol. 1993, 31, 456
3. R. Carini, A. Comoglio, E. Albano, G. Poli, Biochem. Pharmacol. 1992, 43, 2111
4. R. Saller, R. Meier, R. Brignoli, Drugs 2001, 61(14), 2035.
5. L. Cavallini, A. Bindoli, N. Silipandi, Pharmacol. Res. Commun. 1978, 10, 133
6. I. Altorjai, L. Dalmi, B. Sari, S. Imre, G. Balla, Acta Physiol. Hung. 1992, 80, 375
7. I. Gyrgy, S. Antus, A. Blazovics, G. Fldiak, J. Radiat. Biol. 1992, 61, 603.
8. A. Pietrangelo, F. Borella, G. Casalgrandi, Gastroenterology 1995, 109, 1941
9. K. Racz, J. Feher, G. Csomo s, I. Varga, R. Kiss, E. Glaz, J. Endocrinol. 1990, 124, 341
10. Z. Varga, A. Czompa, G. Kakuk, S. Antus, Phytother. Res. 2001, 15, 608.
11. D. K. Sharma, I. H. Hall, J. Nat. Prod. 1991, 54, 1298.
12. G. Scambia, R. DeVincenso, F. Raneletti, P. Panici, P. Benedetti, G. Ferrandina, G. DAgostino, A. Fattorossi, E. Bombardelli, S. Mancuso, Eur. J. Cancer 1996, 32A, 877
13. M. S. A. Afifi, M. M. Ahmed, J. M. Pezzuto, A. D. Kinghorn, Phytochemistry 1993, 34, 839.
14. A. Pelter R. Honsel, Tetrahedron Lett. 1968, 2911
15. H. Wagner, L. Hrhammer, R. Mnster, Arzneim.- Forsch. (Drug Res.) 1968, 18, 688.
16. A. Arnone, L. Merlini, A. Zanarotti, J. Chem. Soc., Chem. Commun. 1979, 696.
17. O. Kazuo, S. Masayoshi, S. Toshiyuki, N. Hirokazu (Taiyo Pharmaceutical Co., Ltd.), Jap. Pat. Kokai Tokkyo Koho JP 62,116,578, 1987
18. Chem. Abstr. 1988, 108, 221499v.
19. G. Stiber, I. Szilagyi, P. Tetenyi, Herba Hung. 1977, 16, 55.
20. I. Szilagyi, P. Tetenyi, S. Antus, O. Seligmann, V. M. Chari, M. Seitz, H. Wagner, Planta Med. 1981, 43, 121.
21. H. Hikino, Y. Kiso, H. Wagner, M. Fiebig, Planta Med. 1984, 50, 248.
22. S. Antus, E. Baitz-Gacs, G. Snatzke, T. S. Toth, Liebigs Ann. Chem. 1991, 633.
23. L. Merlini, A. Zanarotti, A. Pelter, M. P. Rochefort, R. Hnsel, J. Chem. Soc., Chem. Commun. 1979, 695
24. L. Merlini, A. Zanarotti, A. Pelter, M. P. Rochefort, R. Hnsel, J. Chem Soc., Perkin Trans. 1980, 3, 775
25. A. Lotter, H. Z. Wagner, Naturforsch. 1983, 38c, 339
26. D. Y.-W. Lee, Y. Liu, J. Nat. Prod. 2003, 66, 1171.
27. K. Freudenberg, A. C. Neish, 'Constitution and Biosynthesis of Lignins, Springer Verlag, New York, 1968.
28. H. Erdtman, Justus Liebigs Ann. Chem. 1933, 503, 283
29. R. Hnsel, H. Rimpler, Dtsch. Apoth. Ztg. 1968, 108, 1985
30. R. Schrall, H. Becker, Planta Med. 1977, 32, 27.
31. Deutsches Arzneibuch 10. (DAB 10.) 1991 mit 2. Nachtrag, 1993, Band 3, Monographie ber Mariendistelfrchte.
32. S. Nyiredy, K. Dallenbach-Tlke, O. Sticher, J. Planar Chromatogr. 1988, 1, 336
33. S. Nyiredy,W.Wosniok, H. Thile, O. Sticher, J. Liquid Chromatogr. 1991, 14, 3077.
34. N. R. Gruz, F. R. Stermitz, J. B. Johnson, T. D. Beeson, S.Willen, J.-F. Hsiang, K. Lewis, J.Med Chem. 2001, 44, 261.
35. N. R. Gruz, F. R. Stermitz, J. Nat. Prod. 2000, 63, 1140.
36. S. Antus, E. Baitz-Gacs, A. Gottsegen, T. Kovacs, I. Szunyog, T. S. Toth, H. Wagner, Liebigs Ann. Chem. 1993, 105.
37. S. Antus, E. Baitz-Gacs, R. Bauer,A. Gottsegen, O. Seligmann, H.Wagner, Liebigs Ann. Chem. 1989, 1147.
38. E. A. Scherif, A. Islam, M. Krishnamurti, Ind. J. Chem., Sect. B. 1982, 21, 478.
39. W. Gaffield, Tetrahedron 1970, 26, 4093.
40. A. Czompa, Z. Dinya, S. Antus, Z. Varga, Arch. Pharm. 2000, 333, 175.