-
2
-
-
0032482356
-
Help for cytotoxic-T-cell responses is mediated by CD40 signalling
-
Bennett SR, Carbone FR, Karamalis F, Flavell RA, Miller JF, Heath WR. Help for cytotoxic-T-cell responses is mediated by CD40 signalling. Nature. 1998;393:478-480.
-
(1998)
Nature
, vol.393
, pp. 478-480
-
-
Bennett, S.R.1
Carbone, F.R.2
Karamalis, F.3
Flavell, R.A.4
Miller, J.F.5
Heath, W.R.6
-
4
-
-
0032482474
-
T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions
-
Schoenberger SP, Toes RE, van der Voort EI, Offringa R, Melief CJ. T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions. Nature. 1998;393:480-483.
-
(1998)
Nature
, vol.393
, pp. 480-483
-
-
Schoenberger, S.P.1
Toes, R.E.2
Van Der Voort, E.I.3
Offringa, R.4
Melief, C.J.5
-
5
-
-
0037087379
-
T cell immunity to lymphoma following treatment with anti-CD40 monoclonal antibody
-
Tutt AL, O'Brien L, Hussain A, Crowther GR, French RR, Glennie MJ. T cell immunity to lymphoma following treatment with anti-CD40 monoclonal antibody. J Immunol. 2002;168:2720-2728.
-
(2002)
J Immunol
, vol.168
, pp. 2720-2728
-
-
Tutt, A.L.1
O'Brien, L.2
Hussain, A.3
Crowther, G.R.4
French, R.R.5
Glennie, M.J.6
-
6
-
-
0032896709
-
CD40 antibody evokes a cytotoxic T-cell response that eradicates lymphoma and bypasses T-cell help
-
French RR, Chan HT, Tutt AL, Glennie MJ. CD40 antibody evokes a cytotoxic T-cell response that eradicates lymphoma and bypasses T-cell help. Nat Med. 1999;5:548-553.
-
(1999)
Nat Med
, vol.5
, pp. 548-553
-
-
French, R.R.1
Chan, H.T.2
Tutt, A.L.3
Glennie, M.J.4
-
7
-
-
0041737455
-
Anti-CD40 monoclonal antibody therapy in combination with irradiation results in a CD8 T-cell-dependent immunity to B-cell lymphoma
-
Honeychurch J, Glennie MJ, Johnson PW, Illidge TM. Anti-CD40 monoclonal antibody therapy in combination with irradiation results in a CD8 T-cell-dependent immunity to B-cell lymphoma. Blood. 2003;102:1449-1457.
-
(2003)
Blood
, vol.102
, pp. 1449-1457
-
-
Honeychurch, J.1
Glennie, M.J.2
Johnson, P.W.3
Illidge, T.M.4
-
8
-
-
0034141468
-
Induction of CTL responses by simultaneous administration of liposomal peptide vaccine with anti-CD40 and anti-CTLA-4 mAb
-
Ito D, Ogasawara K, Iwabuchi K, Inuyama Y, Onoe K. Induction of CTL responses by simultaneous administration of liposomal peptide vaccine with anti-CD40 and anti-CTLA-4 mAb. J Immunol. 2000;164:1230-1235.
-
(2000)
J Immunol
, vol.164
, pp. 1230-1235
-
-
Ito, D.1
Ogasawara, K.2
Iwabuchi, K.3
Inuyama, Y.4
Onoe, K.5
-
10
-
-
0037117542
-
CD40 stimulation leads to effective therapy of CD40(-) tumors through induction of strong systemic cytotoxic T lymphocyte immunity
-
U S A
-
van Mierlo GJ, den Boer AT, Medema JP, van et al. CD40 stimulation leads to effective therapy of CD40(-) tumors through induction of strong systemic cytotoxic T lymphocyte immunity. Proc Natl Acad Sci U S A. 2002;99:5561-5566.
-
(2002)
Proc Natl Acad Sci
, vol.99
, pp. 5561-5566
-
-
Van Mierlo, G.J.1
Den Boer, A.T.2
Van Medema, J.P.3
-
11
-
-
0037130890
-
The effects of malignant transformation on susceptibility of human urothelial cells to CD40-mediated apoptosis
-
Bugajska U, Georgopoulos NT, Southgate J, et al. The effects of malignant transformation on susceptibility of human urothelial cells to CD40-mediated apoptosis. J Natl Cancer Inst. 2002;94:1381-1395.
-
(2002)
J Natl Cancer Inst
, vol.94
, pp. 1381-1395
-
-
Bugajska, U.1
Georgopoulos, N.T.2
Southgate, J.3
-
12
-
-
0037248746
-
Differential regulation of cell survival by CD40
-
Dallman C, Johnson PW, Packham G. Differential regulation of cell survival by CD40. Apoptosis. 2003;8:45-53.
-
(2003)
Apoptosis
, vol.8
, pp. 45-53
-
-
Dallman, C.1
Johnson, P.W.2
Packham, G.3
-
13
-
-
0034097970
-
Therapeutic activity of agonistic monoclonal antibodies against CD40 in a chronic autoimmune inflammatory process
-
Mauri C, Mars LT, Londei M. Therapeutic activity of agonistic monoclonal antibodies against CD40 in a chronic autoimmune inflammatory process. Nat Med. 2000;6:673-679.
-
(2000)
Nat Med
, vol.6
, pp. 673-679
-
-
Mauri, C.1
Mars, L.T.2
Londei, M.3
-
14
-
-
0035845543
-
CD40 stimulation accelerates deletion of tumor-specific CD8(+) T cells in the absence of tumor-antigen vaccination
-
U S A
-
Kedl RM, Jordan M, Potter T, Kappler J, Marrack P, Dow S. CD40 stimulation accelerates deletion of tumor-specific CD8(+) T cells in the absence of tumor-antigen vaccination. Proc Natl Acad Sci U S A. 2001;98:10811-10816.
-
(2001)
Proc Natl Acad Sci
, vol.98
, pp. 10811-10816
-
-
Kedl, R.M.1
Jordan, M.2
Potter, T.3
Kappler, J.4
Marrack, P.5
Dow, S.6
-
16
-
-
0034095854
-
A dual function for CD40 agonists
-
Zanelli E, Toes RE. A dual function for CD40 agonists. Nat Med. 2000;6:629-630.
-
(2000)
Nat Med
, vol.6
, pp. 629-630
-
-
Zanelli, E.1
Toes, R.E.2
-
17
-
-
0036214292
-
Antigen presentation and T cell stimulation by dendritic cells
-
Guermonprez P, Valladeau J, Zitvogel L, Thery C, Amigorena S. Antigen presentation and T cell stimulation by dendritic cells. Annu Rev Immunol. 2002;20:621-667.
-
(2002)
Annu Rev Immunol
, vol.20
, pp. 621-667
-
-
Guermonprez, P.1
Valladeau, J.2
Zitvogel, L.3
Thery, C.4
Amigorena, S.5
-
18
-
-
0042696999
-
Antigen presentation to naive CD4 T cells in the lymph node
-
Itano AA, Jenkins MK. Antigen presentation to naive CD4 T cells in the lymph node. Nat Immunol. 2003;4:733-739.
-
(2003)
Nat Immunol
, vol.4
, pp. 733-739
-
-
Itano, A.A.1
Jenkins, M.K.2
-
19
-
-
0037769110
-
Dendritic cells in immunity and tolerance - Do they display opposite functions?
-
Moser M. Dendritic cells in immunity and tolerance-do they display opposite functions? Immunity. 2003;19:5-8.
-
(2003)
Immunity
, vol.19
, pp. 5-8
-
-
Moser, M.1
-
21
-
-
0033826369
-
MHC class II and CD40 play opposing roles in dendritic cell survival
-
McLellan A, Heldmann M, Terbeck G, et al. MHC class II and CD40 play opposing roles in dendritic cell survival. Eur J Immunol. 2000;30:2612-2619.
-
(2000)
Eur J Immunol
, vol.30
, pp. 2612-2619
-
-
McLellan, A.1
Heldmann, M.2
Terbeck, G.3
-
22
-
-
0035104229
-
Inhibition of glucocorticoid-mediated, caspase-independent dendritic cell death by CD40 activation
-
Kim KD, Choe YK, Choe IS, Lim JS. Inhibition of glucocorticoid-mediated, caspase-independent dendritic cell death by CD40 activation. J Leukoc Biol. 2001;69:426-434.
-
(2001)
J Leukoc Biol
, vol.69
, pp. 426-434
-
-
Kim, K.D.1
Choe, Y.K.2
Choe, I.S.3
Lim, J.S.4
-
24
-
-
0029812593
-
Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation
-
Cella M, Scheidegger D, Palmer-Lehmann K, Lane P, Lanzavecchia A, Alber G. Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation. J Exp Med. 1996;184:747-752.
-
(1996)
J Exp Med
, vol.184
, pp. 747-752
-
-
Cella, M.1
Scheidegger, D.2
Palmer-Lehmann, K.3
Lane, P.4
Lanzavecchia, A.5
Alber, G.6
-
25
-
-
0032575750
-
Caspases: Enemies within
-
Thornberry NA, Lazebnik Y. Caspases: enemies within. Science. 1998;281:1312-1316.
-
(1998)
Science
, vol.281
, pp. 1312-1316
-
-
Thornberry, N.A.1
Lazebnik, Y.2
-
26
-
-
0035340652
-
Detection of caspases activation by fluorochrome-labeled inhibitors: Multiparameter analysis by laser scanning cytometry
-
Smolewski P, Bedner E, Du L, et al. Detection of caspases activation by fluorochrome-labeled inhibitors: multiparameter analysis by laser scanning cytometry. Cytometry. 2001;44:73-82.
-
(2001)
Cytometry
, vol.44
, pp. 73-82
-
-
Smolewski, P.1
Bedner, E.2
Du, L.3
-
27
-
-
0038393124
-
The death effector domain protein family: Regulators of cellular homeostasis
-
Tibbetts MD, Zheng L, Lenardo MJ. The death effector domain protein family: regulators of cellular homeostasis. Nat Immunol. 2003;4:404-409.
-
(2003)
Nat Immunol
, vol.4
, pp. 404-409
-
-
Tibbetts, M.D.1
Zheng, L.2
Lenardo, M.J.3
-
28
-
-
0028978626
-
TRAF2-mediated activation of NF-kappa B by TNF receptor 2 and CD40
-
Rothe M, Sarma V, Dixit VM, Goeddel DV. TRAF2-mediated activation of NF-kappa B by TNF receptor 2 and CD40. Science. 1995;269:1424-1427.
-
(1995)
Science
, vol.269
, pp. 1424-1427
-
-
Rothe, M.1
Sarma, V.2
Dixit, V.M.3
Goeddel, D.V.4
-
29
-
-
0035900703
-
Molecular characterization of CD40 signaling intermediates
-
Werneburg BG, Zoog SJ, Dang TT, Kehry MR, Crute JJ. Molecular characterization of CD40 signaling intermediates. J Biol Chem. 2001;276:43334-43342.
-
(2001)
J Biol Chem
, vol.276
, pp. 43334-43342
-
-
Werneburg, B.G.1
Zoog, S.J.2
Dang, T.T.3
Kehry, M.R.4
Crute, J.J.5
-
30
-
-
0030698127
-
The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases
-
Roy N, Deveraux QL, Takahashi R, Salvesen GS, Reed JC. The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases. EMBO J. 1997;16:6914-6925.
-
(1997)
EMBO J
, vol.16
, pp. 6914-6925
-
-
Roy, N.1
Deveraux, Q.L.2
Takahashi, R.3
Salvesen, G.S.4
Reed, J.C.5
-
31
-
-
0036629347
-
Apoptotic crosstalk of TNF receptors: TNF-R2-induces depletion of TRAF2 and IAP proteins and accelerates TNF-R1-dependent activation of caspase-8
-
Fotin-Mleczek M, Henkler F, Samel D, et al. Apoptotic crosstalk of TNF receptors: TNF-R2-induces depletion of TRAF2 and IAP proteins and accelerates TNF-R1-dependent activation of caspase-8. J Cell Sci. 2002;115:2757-2770.
-
(2002)
J Cell Sci
, vol.115
, pp. 2757-2770
-
-
Fotin-Mleczek, M.1
Henkler, F.2
Samel, D.3
-
32
-
-
0036133127
-
Molecular ordering of the initial signaling events of CD95
-
Algeciras-Schimnich A, Shen L, Barnhart BC, Murmann AE, Burkhardt JK, Peter ME. Molecular ordering of the initial signaling events of CD95. Mol Cell Biol. 2002;22:207-220.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 207-220
-
-
Algeciras-Schimnich, A.1
Shen, L.2
Barnhart, B.C.3
Murmann, A.E.4
Burkhardt, J.K.5
Peter, M.E.6
-
33
-
-
0038198615
-
Actin dependent CD95 internalization is specific for type I cells
-
Algeciras-Schimnich A, Peter ME. Actin dependent CD95 internalization is specific for type I cells. FEBS Lett. 2003;546:185-188.
-
(2003)
FEBS Lett
, vol.546
, pp. 185-188
-
-
Algeciras-Schimnich, A.1
Peter, M.E.2
-
35
-
-
0033583191
-
Fas ligand-independent, FADD-mediated activation of the Fas death pathway by anticancer drugs
-
Micheau O, Solary E, Hammann A, Dimanche-Boitrel MT. Fas ligand-independent, FADD-mediated activation of the Fas death pathway by anticancer drugs. J Biol Chem. 1999;274:7987-7992.
-
(1999)
J Biol Chem
, vol.274
, pp. 7987-7992
-
-
Micheau, O.1
Solary, E.2
Hammann, A.3
Dimanche-Boitrel, M.T.4
-
36
-
-
0033548603
-
Cycloheximide-induced T-cell death is mediated by a Fas-associated death domain-dependent mechanism
-
Tang D, Lahti JM, Grenet J, Kidd VJ. Cycloheximide-induced T-cell death is mediated by a Fas-associated death domain-dependent mechanism. J Biol Chem. 1999;274:7245-7252.
-
(1999)
J Biol Chem
, vol.274
, pp. 7245-7252
-
-
Tang, D.1
Lahti, J.M.2
Grenet, J.3
Kidd, V.J.4
-
37
-
-
0031943921
-
Ultraviolet light induces apoptosis via direct activation of CD95 (Fas/APO-1) independently of its ligand CD95L
-
Aragane Y, Kulms D, Metze D, et al. Ultraviolet light induces apoptosis via direct activation of CD95 (Fas/APO-1) independently of its ligand CD95L. J Cell Biol. 1998;140:171-182.
-
(1998)
J Cell Biol
, vol.140
, pp. 171-182
-
-
Aragane, Y.1
Kulms, D.2
Metze, D.3
-
38
-
-
0035896589
-
c-Jun NH2-terminal kinase activation leads to a FADD-dependent but Fas ligand-independent cell death in Jurkat T cells
-
Chen Y, Lai MZ. c-Jun NH2-terminal kinase activation leads to a FADD-dependent but Fas ligand-independent cell death in Jurkat T cells. J Biol Chem. 2001;276:8350-8357.
-
(2001)
J Biol Chem
, vol.276
, pp. 8350-8357
-
-
Chen, Y.1
Lai, M.Z.2
-
39
-
-
0033571320
-
Dendritic cells are resistant to apoptosis through the Fas (CD95/APO-1) pathway
-
Ashany D, Savir A, Bhardwaj N, Elkon KB. Dendritic cells are resistant to apoptosis through the Fas (CD95/APO-1) pathway. J Immunol. 1999;163:5303-5311.
-
(1999)
J Immunol
, vol.163
, pp. 5303-5311
-
-
Ashany, D.1
Savir, A.2
Bhardwaj, N.3
Elkon, K.B.4
-
40
-
-
0034307531
-
Maturation of dendritic cells leads to up-regulation of cellular FLICE-inhibitory protein and concomitant down-regulation of death ligand-mediated apoptosis
-
Leverkus M, Walczak H, McLellan A, et al. Maturation of dendritic cells leads to up-regulation of cellular FLICE-inhibitory protein and concomitant down-regulation of death ligand-mediated apoptosis. Blood. 2000;96:2628-2631.
-
(2000)
Blood
, vol.96
, pp. 2628-2631
-
-
Leverkus, M.1
Walczak, H.2
McLellan, A.3
-
41
-
-
0028799935
-
Fas ligation induces apoptosis of CD40-activated human B lymphocytes
-
Garrone P, Neidhardt EM, Garcia E, Galibert L, van Kooten C, Banchereau J. Fas ligation induces apoptosis of CD40-activated human B lymphocytes. J Exp Med. 1995;182:1265-1273.
-
(1995)
J Exp Med
, vol.182
, pp. 1265-1273
-
-
Garrone, P.1
Neidhardt, E.M.2
Garcia, E.3
Galibert, L.4
Van Kooten, C.5
Banchereau, J.6
-
42
-
-
0028865583
-
CD40 ligation induces Apo-1/Fas expression on human B lymphocytes and facilitates apoptosis through the Apo-1/Fas pathway
-
Schattner EJ, Elkon KB, Yoo DH, et al. CD40 ligation induces Apo-1/Fas expression on human B lymphocytes and facilitates apoptosis through the Apo-1/Fas pathway. J Exp Med. 1995;182:1557-1565.
-
(1995)
J Exp Med
, vol.182
, pp. 1557-1565
-
-
Schattner, E.J.1
Elkon, K.B.2
Yoo, D.H.3
-
43
-
-
0037133603
-
Latent sensitivity to Fas-mediated apoptosis after CD40 ligation may explain activity of CD154 gene therapy in chronic lymphocytic leukemia
-
U S A
-
Chu P, Deforce D, Pedersen IM, et al. Latent sensitivity to Fas-mediated apoptosis after CD40 ligation may explain activity of CD154 gene therapy in chronic lymphocytic leukemia. Proc Natl Acad Sci U S A. 2002;99:3854-3859.
-
(2002)
Proc Natl Acad Sci
, vol.99
, pp. 3854-3859
-
-
Chu, P.1
Deforce, D.2
Pedersen, I.M.3
-
44
-
-
1142287412
-
Ligand-independent redistribution of Fas (CD95) into lipid rafts mediates clonotypic T cell death
-
Muppidi JR, Siegel RM. Ligand-independent redistribution of Fas (CD95) into lipid rafts mediates clonotypic T cell death. Nat Immunol. 2004;5:182-189.
-
(2004)
Nat Immunol
, vol.5
, pp. 182-189
-
-
Muppidi, J.R.1
Siegel, R.M.2
-
45
-
-
5644222552
-
Life and death decisions: Secondary complexes and lipid rafts in TNF receptor family signal transduction
-
Muppidi JR, Tschopp J, Siegel RM. Life and death decisions: secondary complexes and lipid rafts in TNF receptor family signal transduction. Immunity. 2004;21:461-465.
-
(2004)
Immunity
, vol.21
, pp. 461-465
-
-
Muppidi, J.R.1
Tschopp, J.2
Siegel, R.M.3
-
46
-
-
0036533670
-
Defining the dynamics of self-assembled Fas-receptor activation
-
Mundle SD, Raza A. Defining the dynamics of self-assembled Fas-receptor activation. Trends Immunol. 2002;23:187-194.
-
(2002)
Trends Immunol
, vol.23
, pp. 187-194
-
-
Mundle, S.D.1
Raza, A.2
-
47
-
-
0035862333
-
Antigen-specific inhibition of effector T cell function in humans after injection of immature dendritic cells
-
Dhodapkar MV, Steinman RM, Krasovsky J, Munz C, Bhardwaj N. Antigen-specific inhibition of effector T cell function in humans after injection of immature dendritic cells. J Exp Med. 2001;193:233-238.
-
(2001)
J Exp Med
, vol.193
, pp. 233-238
-
-
Dhodapkar, M.V.1
Steinman, R.M.2
Krasovsky, J.3
Munz, C.4
Bhardwaj, N.5
-
48
-
-
0036659913
-
Antigen-bearing immature dendritic cells induce peptide-specific CD8(+) regulatory T cells in vivo in humans
-
Dhodapkar MV, Steinman RM. Antigen-bearing immature dendritic cells induce peptide-specific CD8(+) regulatory T cells in vivo in humans. Blood. 2002;100:174-177.
-
(2002)
Blood
, vol.100
, pp. 174-177
-
-
Dhodapkar, M.V.1
Steinman, R.M.2
-
49
-
-
0032960197
-
Generation of tumor immunity by bone marrow-derived dendritic cells correlates with dendritic cell maturation stage
-
Labeur MS, Roters B, Pers B, et al. Generation of tumor immunity by bone marrow-derived dendritic cells correlates with dendritic cell maturation stage. J Immunol. 1999;162:168-175.
-
(1999)
J Immunol
, vol.162
, pp. 168-175
-
-
Labeur, M.S.1
Roters, B.2
Pers, B.3
-
50
-
-
0036721808
-
Activation of APCs through CD40 or Toll-like receptor 9 overcomes tolerance and precipitates autoimmune disease
-
Ichikawa HT, Williams LP, Segal BM. Activation of APCs through CD40 or Toll-like receptor 9 overcomes tolerance and precipitates autoimmune disease. J Immunol. 2002;169:2781-2787.
-
(2002)
J Immunol
, vol.169
, pp. 2781-2787
-
-
Ichikawa, H.T.1
Williams, L.P.2
Segal, B.M.3
-
51
-
-
0037093862
-
CD40 ligation in the presence of self-reactive CD8 T cells leads to severe immunopathology
-
Roth E, Schwartzkopff J, Pircher H. CD40 ligation in the presence of self-reactive CD8 T cells leads to severe immunopathology. J Immunol. 2002;168:5124-5129.
-
(2002)
J Immunol
, vol.168
, pp. 5124-5129
-
-
Roth, E.1
Schwartzkopff, J.2
Pircher, H.3
-
52
-
-
14144250884
-
Inhibition of TNF alpha during maturation of dendritic cells results in the development of semimature cells: A potential mechanism by which TNF alpha blockade exerts its beneficial effects in rheumatoid arthritis
-
van Lieshout TW, Barrera P, Smeets RL, et al. Inhibition of TNF alpha during maturation of dendritic cells results in the development of semimature cells: a potential mechanism by which TNF alpha blockade exerts its beneficial effects in rheumatoid arthritis. Ann Rheum Dis. 2005;64:408-414.
-
(2005)
Ann Rheum Dis
, vol.64
, pp. 408-414
-
-
Van Lieshout, T.W.1
Barrera, P.2
Smeets, R.L.3
|